Jurnal Gizi Klinik Indonesia
Vol 13, No 4 (2017): April

Pengaruh pemberian yogurt sinbiotik tepung pisang tanduk terhadap profil lipid tikus sindrom metabolik

Zana Fitriana Octavia (Program Studi Magister Ilmu Gizi, Fakultas Kedokteran Universitas Diponegoro)
Kis Djamiatun (Bagian Biomedik, Fakultas Kedokteran Universitas Diponegoro)
Nyoman Suci (Bagian Patologi Klinik, Fakultas Kedokteran Universitas Diponegoro / Rumah Sakit Umum Pusat Dr. Karyadi)



Article Info

Publish Date
28 Apr 2017

Abstract

Background: The metabolic syndrome, which is characterized by hyperglycemia, obesity, dyslipidemia, hypertension, prothrombic and proinflamatory state, is a risk factor for cardiovascular disease and diabetes mellitus. The synbiotic yogurt of tanduk banana (Musa paradisiaca fa. corniculata) flour contains lactic acid bacteria, fructooligosaccarides, flavonoids, and vitamin C which all of them play role in improving the lipid profile.Objective: The aim of this study was to prove the effect of synbiotic yogurt of tanduk banana flour on lipid profile of metabolic syndrome rats.Method: This study was an true experimental with pre-post test  control group design. The subject of this study were 18 metabolic syndrome male Wistar rats divided into 3 groups,i.e control group (standart diet), intervention group I (standart diet and synbiotic yogurt of banana flour 0,009 ml/g weight/day), and intervention group II (standart diet and synbiotic yogurt of banana flour 0,018 ml/g weight/day). The intervention period was 2 weeks. Different test before and after intervention used paired t-test. The difference test between groups used One-Way ANOVA and Kruskal wallis.Results: The result showed that both of intervention group improved lipid profile significantly (p<0,05). The intervention group II showed more effective improvement of lipid profile significantly (p<0,05) than intervention group I. The intervention group II decreased triglycerides level 41,56%; total cholesterol level 41,39%; LDL-cholesterol level 57,5%; and increased HDL-cholesterol level 139,62%.Conclucion: The intervention of synbiotic yogurt of  tanduk banana flour can decrease triglyceride level, total cholesterol level, LDL-cholesterol level, and increase HDL-cholesterol level.

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Journal Info

Abbrev

jgki

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Nursing Public Health

Description

Jurnal Gizi Klinik Indonesia merupakan jurnal ilmiah nasional terakreditasi yang memuat artikel penelitian (research article) di bidang gizi dan kesehatan, yang terkait aspek gizi klinis, gizi masyarakat, gizi olahraga, gizi molekular, biokimia gizi, pangan fungsional, serta pelayanan dan manajemen ...