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Jurnal Farmasi Sains dan Komunitas

JFSK
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Published by Universitas Sanata Dharma

ISSN : 16935683 EISSN : 25277146 DOI : https://doi.org/10.24071/

Core Subject : Health,

Medicine & Pharmacology

Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community / J Pharm Sci Community) firstly published in 2003, is a peer-reviewed, open access scientific journal that publishes research articles, review articles, as well as short communication in various pharmaceutical fields, including Pharmaceutical Technology and Pharmaceutics, Pharmaceutical Analysis, Medicinal Chemistry, Pharmacology and Toxicology, Pharmaceutical Biology, Community Pharmacy, and Clinical Pharmacy.

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 7 Documents

Search results for , issue "Vol 15, No 2 (2018)" : 7 Documents clear

FORMULATION OF SUNSCREEN CREAM OF PARIJOTO FRUIT EXTRACT (Medinilla speciosa Blume) AND IN VITRO SPF VALUE TEST Elsa Tamara Geraldine; Ema Dwi Hastuti
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 15, No 2 (2018)
Publisher : Sanata Dharma University

Sunscreen preparations are cosmetic preparations used as a protection to reduce the impact of sun exposure whose formulations contain active ingredients to absorb or diffuse sunlight, especially in areas of ultraviolet and infrared wave emissions. One of the potential natural ingredients for a sunscreen is parijoto fruit (Medinilla speciosa Blume). It contains flavonoid compounds that are able to prevent the harmful effects of UV rays. The objective of this research is to find out the formula of sunscreen cream of parijoto extract that meets the good physical quality of cream and to find out the result of SPF value test of parijoto fruit extract as sunscreen cream preparation in Vitro. The design of the study was experimental research conducted in the laboratory. The sample used in this research was parijoto made into thick extract by maceration method. Further, the viscous extract obtained was made to be a sunscreen cream and then tested either its physical evaluation or calculation of SPF value. The results of this study indicate that the preparation of sunscreen cream of parijoto fruit extract included in the extra protection category with the value is 6.66 and can be made into the good and stable preparations. The sunscreen cream of parijoto fruit extract has good physical properties and also has activity as UV protection in vitro.

COMPOUNDING STERILE PREPARATIONS FOR INTENSIVE CARE UNIT PATIENTS (ICU) IN ONE PRIVATE HOSPITAL IN SEMARANG Sara Septi Widayani; Sri Hartati Yuliani; Dina Christin Ayuning Putri
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 15, No 2 (2018)
Publisher : Sanata Dharma University

Sterile preparations for intravenous injection probably cause greater risk of errors than other preparation treatment routes due to their complex preparation steps. Errors in preparation and compounding stage will affect the quality and stability of the pharmaceutical product obtained. The aim of this study was to evaluate the process of compounding and assess both quality and stability of the parenteral preparations products that resulted from the compounding process for ICUs patients in one private hospital in Semarang, Central Java, Indonesia. This observational analytic study was conducted using accidental sampling technique. The descriptive study results showed that sterile preparation in hospital X was not performed according to the Guidelines for Drug Injection and Handling of Cytostatic Preparations. In order to evaluate the quality of the sterile preparations, three different drugs with the highest prevalence of use: namely ceftriaxone, meropenem and omeprazole were evaluated. It was found that the pH value of omeprazole was not acceptable due to the use of an appropriateness solvent. The sterility tests showed that the preparation products prepared by the nurses were free from microorganisms.

SPRAY DRIED AQUEOUS EXTRACT OF LEMONGRASS (Cymbopogon citratus) EXHIBITS IN VITRO AND IN VIVO ANTI HYPERGLYCEMIC ACTIVITIES Maria Dewi Puspitasari Tirtaningtyas Gunawan-Puteri; Felicia Rustandi; Phebe Hendra
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 15, No 2 (2018)
Publisher : Sanata Dharma University

Lemongrass was found to be a promising herb for anti-hyperglycemia treatment due to its activities to inhibit alpha glucosidase and alpha amylase in vitro activities and ability to improve blood glucose profile. Lemongrass potency through its anti-hyperglycemic ingredients requires evaluation of the functional stability during processing. In this study, the in vitro anti-hyperglycemic activities of spray-dried aqueous extract of lemongrass were determined by its inhibitory activity against rat intestinal glucosidase enzymatic hydrolysis of sucrose. In vivo activity was observed based on its ability to prevent blood glucose elevation in oral glucose, sucrose and maltose tolerance tests (OGTT, OSTT and OMTT). The in vitro evaluation showed that aqueous extraction, which involved stirring at 70 C for 40 min, successfully increased the glucosidase inhibitory activity of lemongrass extract, while spray drying with inlet 130 C had no significant impact to the activity tested in vitro. Spray-dried lemongrass powder was found to be effective for lowering blood glucose level in OGTT, OSTT and OMTT. This study provides support for further development of lemongrass extracts as functional ingredients for hyperglycemia treatment.

THE EFFECT OF EDUCATIONAL SELF-MEDICATION FOR DYSMENORRHEA TREATMENT USING OVER THE COUNTER DRUGS Betti Dwi Kartikasari; Yustina Emi Setyobudi
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 15, No 2 (2018)
Publisher : Sanata Dharma University

Self-medication is an attempt to treat the disease felt by using the over-the-counter drug (OTC) which is based on knowledge about the safe and rational treatment. The implementation of the self-medication drug use tends to be misused. The ease in self-medication treatment in community shows the importance of education in the use of medications safely and rationally. Education is carried out appropriately with effective methods and media. This research used quasi-experimental design approach with one group pretest posttest design. The sample of this research was 34 female students from Frateran High School Malang selected using a purposive sampling. The data was analyzed using Paired T-Test. The results of comparison of self-medication treatment using OTC drugs before (pre) and after (post) education provided the significance value obtained 0.000 which is smaller than alpha 0.05. The null hypothesis (H0) can be rejected and concluded that there is a different score in the self-medication treatment using OTC drugs before (pre) and after (post) education. It can be concluded that the education can affect the improvement of knowledge of the students for effectiveness of lowering OTC drugs abuse.

THE EFFECT OF HEALTH INSURANCE ON ASTHMA CONTROL IN RESPONDENTS WITH ASTHMA IN YOGYAKARTA, INDONESIA Rita Suhadi; Fenty Fenty; Dita Maria Virginia; Christianus Heru Setiawan
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 15, No 2 (2018)
Publisher : Sanata Dharma University

Asthma is a chronic disease with recurrent breath shortness. Until now, there is no particular therapy to cure the disease and long-term treatment is needed to control the disease. Health insurance has the benefit to support the asthma therapy. This study aimed to assess the effect of health insurance on the asthma control based on Asthma Control Test (ACT) score. The study was done with a cross-sectional design on respondents with asthma who agreed to sign informed consent forms in Yogyakarta. The asthma respondents (n=36) were selected non-randomly, consisting of 23 respondents with health insurance, including universal health coverage or UHC (n=15), UHC and private insurance (n=7), and private insurance only (n=1). The ratio and categorical data were analyzed with the independent T-test or Mann-Whitney test and chi-square statistics, respectively. The study demonstrated that the profiles and number of medicines were similar between groups, except for lower smoking proportion among health insurance groups; the respondents with and without health insurance had the median ACT score at 22 (partial control) and 15 (bad control) respectively, though the scores were not statistically different. Conclusion: the asthma respondents with and without health insurance were not statistically different in the asthma control.

THE EFFECT OF NaOH CONCENTRATION IN DELIGNIFICATION PROCESS ON MICROCRYSTALLINE CELLULOSE FROM GREEN ALGAE (Cladophora sp.) AS THE RENEWABLE MARINE PRODUCT I Gusti Ngurah Jemmy Anton Prasetia; Shelia Deviana; Trisna Damayanti; Angga Cahyadi; I Made Agus Gelgel Wirasuta
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 15, No 2 (2018)
Publisher : Sanata Dharma University

Research on marine natural resources as an excipient material of pharmaceutical product is still rare. One of the marine products is the green algae, Cladophora sp. High cellulose content causes Cladophora sp. which can be used as an alternative material of microcrystalline cellulose (SM). There are two stages to produce SM, namely delignification and hydrolysis. Delignification is the process of removing the lignin of complex compounds. The delignification process is carried out chemically in alkaline situation using a NaOH solution which dissolves lignin, carbohydrates, organic acids, and resins so that cellulose is released from its bonds. This is important because the presence of lignin may inhibit acid penetration prior to hydrolysis. Therefore, the purpose of this study is to investigate the effect of delignification by using NaOH solution at various concentrations (2, 4, and 6%) to cellulose content and physical character of microcrystalline cellulose from Cladophora sp. (SMC). In the hydrolysis process, 5% HCl solution was used. SMCs of various concentrations of NaOH were observed and the cellulose levels included alpha, beta and gamma levels. While the physical character observation is done on Scanning Electron Microscopy (SEM) test. Based on the cellulose content, the higher the concentration of NaOH used, the higher the alpha cellulose will increase. The opposite result occurs on the measurement of beta and gamma cellulose. Based on SEM test, it appears that there is no effect of increasing NaOH concentration on physical character of SMC.

STANDARDIZATION OF EXTRACT AND CHARACTERIZATION OF EMULGEL FORMULA OF LENGKUAS (Alpinia galanga (L.) Willd) RHIZOME EXTRACT Widyasari Putranti; Novia Ariani Dewi; Lina Widiyastuti
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 15, No 2 (2018)
Publisher : Sanata Dharma University

The lengkuas rhizome has an antifungal activity. The non-specific parameters for extracts of lengkuas rhizome need to be standardized to obtain the extracts with consistent good quality. The lengkuas rhizome extract emulgel topical preparations are easily mixed with active substances that are hydrophobic or hydrophilic. This study aims to obtain a lengkuas rhizome extract emulgel formula that has good quality and good physical properties. Extraction of lengkuas rhizome was obtained using a maceration method with 96% ethanol solvent. The extract is standardized by non-specific parameters. After that, the extract was formulated in the form of emulgel preparation with 10% concentration. The physical properties of emulgel were evaluated. The results of the study showed that the extract yield is of (14.660.056)%; powder drying shrinkage (8.630.134)%; extract water rate (50)%; powder total ash rate (3.240.017)%; and extract (1.300.035)%; acid-insoluble ash rate powder (2.660.10)%; and extract (0.870.031)%; extract type weight 1.01; and the physical properties of emulgel preparations were homogeneous emulgel, semisolid form, light brown color, distinctive smell of lengkuas rhizome extract, stable at 5oC and 25oC for 24 hours; pH 7; spreadability (2.450.03) g.cm.s-1; stickiness (8.800.72) seconds; o/w emulsion type; and viscosity (1.370.22) Pa.s. This study obtained extracts of lengkuas rhizomes that meet the requirements of non-specific parameter standardization in general and the formulation of lengkuas rhizome extract emulgel had good physical properties.

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Florentinus Dika Octa Riswanto

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Faculty of Pharmacy, Universitas Sanata Dharma, Indonesia

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Kab. sleman,

Daerah istimewa yogyakarta

INDONESIA

Abstract

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Florentinus Dika Octa Riswanto

Contact Email editorial.jpsc@usd.ac.id

Phone -

Journal Mail Official editorial.jpsc@usd.ac.id

Editorial Address Faculty of Pharmacy, Universitas Sanata Dharma, Indonesia

Location Kab. sleman, Daerah istimewa yogyakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Florentinus Dika Octa Riswanto

Contact Email
editorial.jpsc@usd.ac.id

Phone
-

Journal Mail Official
editorial.jpsc@usd.ac.id

Editorial Address
Faculty of Pharmacy, Universitas Sanata Dharma, Indonesia

Location
Kab. sleman,

Daerah istimewa yogyakarta

INDONESIA