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Universa Medicina
Published by Universitas Trisakti
ISSN : 19073062     EISSN : 24072230     DOI : -
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Universa Medicina (univ.med) is a four-monthly medical journal that publishes new research findings on a wide variety of topics of importance to biomedical science and clinical practice. Universa Medicina Online contains both the current issue and an online archive that can be accessed through browsing, advanced searching, or collections by disease or topic
Arjuna Subject : -
Articles 3 Documents
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Search results for , issue " Vol 30, No 1 (2011)" : 3 Documents clear
Day-care patients and inpatients have similar visual acuity Kartadinata, Erlani
Universa Medicina Vol 30, No 1 (2011)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2011.v30.22-28

Abstract

Cataract is a cause of avoidable blindness and its prevalence increases with age. Cataract surgery is the only possible therapeutic modality for improving visual function in cataract patients. The rising numbers of cataract patients require a type of cataract surgery with minimal side effects and without hospitalization. In this connection the day care cataract surgery has been introduced, with excellent results. Therefore the aim of the present study was to compare the visual acuity of day-care patients and inpatients after extracapsular cataract extraction (ECCE). A comparative observational study was carried out on 30 mature senile cataract patients with regard to type of care after ECCE surgery. The study subjects were allocated to two groups of 15 subjects each, i.e. the day-care group and the in-patient group. The patients were observed postoperatively on the first day, first week, fourth week, and eighth week. They subsequently were corrected for best visual acuity. Hypothesis testing was done using independent t-test and the Mann-Whitney test. The study results indicated that the visual acuity of the subjects after the eighth postoperative week did not differ significantly between both groups (p>0.05). There was no significant difference in outcome or risk of postoperative complications between day care and in-patient cataract surgery.This study therefore presents evidence that both post-ECCE day-care as well as post-ECCE inpatients had similar visual acuity levels.
Prognosis and management of polymyalgia rheumatica Samara, Diana
Universa Medicina Vol 30, No 1 (2011)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2011.v30.63-70

Abstract

Polymyalgia rheumatica (PMR) is commonly found in Northern Europe and in persons of Scandinavian extraction in the US, with an annual incidence of around 50 per 100,000 population over 50 years of age, in whom it should be           considered in the differential diagnosis of musculoskeletal disorders. The     disorder is twice more common in women than in men. PMR is closely related to giant cell arteritis and both disorders are considered to have a common    pathogenesis, associated with genetic and environmental factors (viral and   bacterial infections). There is no gold diagnostic standard for PMR and the diagnosis rests on a high index of suspicion in persons older than 50 years with musculoskeletal symptoms. As an aid in diagnosis, several sets of diagnostic criteria have been used, usually related to age at onset, duration, symptoms, inflammatory markers, and response to corticosteroids. Patients with PMR   usually present with acute onset of stiffness and pain in the shoulder and pelvic musculature, which may be accompanied by fever, malaise, and weight loss. The symptoms of PMR seem to be related to synovitis of proximal joints and extra-articular synovial structures. PMR may occur as an isolated syndrome or accompany other diseases, mainly giant cell arteritis. It usually responds quickly to once-daily, low-dose prednisone, but some patients require treatment for  several years. Monitoring for corticosteroid-associated side effects such as   osteoporosis and diabetes, as well as for relapses and flare-ups, is key to chronic management.
Analgesic activity of ethanolic extract of Manihot esculenta Crantz leaves in mice Miladiyah, Isnatin
Universa Medicina Vol 30, No 1 (2011)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2011.v30.3-10

Abstract

Cassava (Manihot esculenta Crantz) leaves have long been used as a vegetable in many countries and empirically as a febrifuge. The aim of the present study was to evaluate the analgesic activity of an ethanolic extract of cassava leaves in mice. Thirty Balb/c mice (20-30 g, 2-3 months old) were randomly divided into 6 groups. Group I was given distilled water 1 mL as negative control, group II paracetamol 65 mg/kgBW as positive control, and group III-VI received an ethanolic extract of cassava leaves in 4 doses, i.e. 12.8 mg/kgBW, 25.6 mg/kgBW, 51.3 mg/kgBW, and 102.6 mg/kgBW, respectively. All interventions were administered as a single dose by oral route on a given day. Acetic acid 0.6% (w/v) was used as a pain inductor. Analgesic activity was measured by counting the percentage of writhing movements as a measure of the analgesic effect  produced by each intervention. Data were analyzed with one-way Anova to compare analgesic activity between treatment groups. The results showed that groups treated with ethanolic extract of cassava leaves at dosages of 12.8 mg/kgBW, 25.6 mg/kgBW, 51.3 mg/kgBW, and 102.6 mg/kgBW had an analgesic activity of 59.2%; 73.9%; 62.1%; and 55.9%, respectively. On statistical analysis there were significant differences (p=0.00) between these treatments compared to the negative control, but no significant differences (p>0.05) with the positive control (paracetamol). It may be concluded that the analgesic effect of an ethanolic extract of cassava (Manihot esculenta Crantz) leaves in mice was of similar potency as paracetamol.

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