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INDONESIA
Universa Medicina
Published by Universitas Trisakti
ISSN : 19073062     EISSN : 24072230     DOI : -
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Universa Medicina (univ.med) is a four-monthly medical journal that publishes new research findings on a wide variety of topics of importance to biomedical science and clinical practice. Universa Medicina Online contains both the current issue and an online archive that can be accessed through browsing, advanced searching, or collections by disease or topic
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Articles 2 Documents
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Search results for , issue " Vol 37, No 3 (2018)" : 2 Documents clear
Duration of dialysis increases risk of hepatitis C virus infections among hemodialysis patients in Anambra state, Nigeria Chizoba, Okeke Okechukwu; Chibuogwu, Ajulu A
Universa Medicina Vol 37, No 3 (2018)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1271.876 KB) | DOI: 10.18051/UnivMed.2018.v37.173-180

Abstract

Background Sexually transmitted infections and syphilis are a major public health concern. Hemodialysis patients are at an increased risk of acquiring hepatitis B virus (HBV) and hepatitis C virus (HCV) infection. The aim of this study was to determine the seroprevalence of HBV, HCV, syphilis, and the association between these infections and hemodialysis among hemodialysis patients.MethodsA cross-sectional study was conducted involving 90 hemodialysis patients. Blood samples were collected and analysed for HBV, HCV and syphilis using immunochromatographic test kits. All subjects completed a questionnaire on demographic characteristics and other risk factors. A chi-square test was used to analyse the data.ResultsThe prevalence of HBV, HCV and syphilis infections was 4.4%, 6.7% and 2.2% respectively. Highest prevalence of HBV, HCV and syphilis were found in patients whose duration of dialysis were >1 year, >1 year, and 4 months to 1 year, respectively. Similarly, those who had undergone dialysis for > 10 times had the highest prevalence of these infections. The major risk factor the patients was exposed to was blood transfusion (100%), with those who had been transfused for 5 times having the highest prevalence of HBV and HCV and those transfused twice for syphilis. A significant association was seen between duration of dialysis and HCV infection (p<0.05).ConclusionThis study has demonstrated that duration of dialysis increased HCV infection in hemodialysis patients. The prevalence of HBV, HCV and syphilis in the hemodialysis unit is a warning that universal precautions will be the next challenge for decentralised hemodialysis services.
Later age at menopause was associated with higher cognitive function in post-menopausal women Rachmiyani, Irmiya; Surjadi, Lily Marliany; Nirmalasari, Rully Ayu; Imran, Yudhisman
Universa Medicina Vol 37, No 3 (2018)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (736.075 KB) | DOI: 10.18051/UnivMed.2018.v37.203-208

Abstract

BACKGROUND Menopause is a condition in which the menstrual periods have stopped for the last 12 months due to cessation of ovarial functions causing estrogen hormones to decrease. Various studies find that many factors affect cognitive function at post-menopausal age among others the decrease in estrogens, age at menopause, duration of menopause, and education. However, the effects have been subject to controversy. The aim of this study was to determine the relationship of age, age at menopause, estradiol level, and education with cognitive function among healthy post-menopausal women. METHODS A cross-sectional study was conducted involving 31 post-menopausal women between 50 to 75 years old. Data on age, age at menopause, and education were collected using a questionnaire. The estradiol levels were measured using an electrochemiluminescent immunoassay (ECLIA). The Indonesian version of the Montreal Cognitive Assessment (MoCA INA) was used to assess the cognitive function. Multiple linear regression was used to analyze the data. A p<0.05 was considered statistically significant.RESULTS Age (b=-0.086; 95% C.I.=-0.263-0.090; p=324) and estradiol levels (b=0.106; 95% C.I.=-0.018 -0.230; p=0.092) were not significantly associated with cognitive function. However, education (b=1.537; 95% C.I.=0.176-2.898; p=0.028) and age at menopause (b=0.364;0.056-0.671; p=0.022) were significantly associated with cognitive function. Age at menopause was the most influential factor of cognitive function (Beta=0.402) compared to education (Beta=0.394).CONCLUSION Later age at menopause could increase cognitive function in post-menopausal women. Our findings are that modifiable factors that delay age at menopause should receive attention, in order to promote cognitive function. Keywords: Age at menopause, estrogens, cognitive function, post-menopausal women

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