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All Journal Universa Medicina Jurnal Biomedika dan Kesehatan Jurnal Penelitian dan Karya Ilmiah Lembaga Penelitian Universitas Trisakti Jurnal Pengabdian Masyarakat Trimedika
Surjadi, Lily Marliany
Faculty of Medicine, Trisakti University
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Later age at menopause was associated with higher cognitive function in post-menopausal women Rachmiyani, Irmiya; Surjadi, Lily Marliany; Nirmalasari, Rully Ayu; Imran, Yudhisman
Universa Medicina Vol 37, No 3 (2018)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (736.075 KB) | DOI: 10.18051/UnivMed.2018.v37.203-208

Abstract

BACKGROUND Menopause is a condition in which the menstrual periods have stopped for the last 12 months due to cessation of ovarial functions causing estrogen hormones to decrease. Various studies find that many factors affect cognitive function at post-menopausal age among others the decrease in estrogens, age at menopause, duration of menopause, and education. However, the effects have been subject to controversy. The aim of this study was to determine the relationship of age, age at menopause, estradiol level, and education with cognitive function among healthy post-menopausal women. METHODS A cross-sectional study was conducted involving 31 post-menopausal women between 50 to 75 years old. Data on age, age at menopause, and education were collected using a questionnaire. The estradiol levels were measured using an electrochemiluminescent immunoassay (ECLIA). The Indonesian version of the Montreal Cognitive Assessment (MoCA INA) was used to assess the cognitive function. Multiple linear regression was used to analyze the data. A p<0.05 was considered statistically significant.RESULTS Age (b=-0.086; 95% C.I.=-0.263-0.090; p=324) and estradiol levels (b=0.106; 95% C.I.=-0.018 -0.230; p=0.092) were not significantly associated with cognitive function. However, education (b=1.537; 95% C.I.=0.176-2.898; p=0.028) and age at menopause (b=0.364;0.056-0.671; p=0.022) were significantly associated with cognitive function. Age at menopause was the most influential factor of cognitive function (Beta=0.402) compared to education (Beta=0.394).CONCLUSION Later age at menopause could increase cognitive function in post-menopausal women. Our findings are that modifiable factors that delay age at menopause should receive attention, in order to promote cognitive function. Keywords: Age at menopause, estrogens, cognitive function, post-menopausal women
HUBUNGAN USIA MENARCHE DENGAN KEJADIAN GEJALA PREMENSTRUAL PADA REMAJA Surjadi, Lily Marliany; Inshira, Feysha Nazla
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Volume 10, Nomor 2, Juli 2025
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v10i2.16425

Abstract

Menarche atau menstruasi pertama merupakan suatu tahap yang menandai kematangan seorang remaja puteri. Kumpulan keluhan fisik, emosional maupun perilaku yang terjadi dalam waktu 7-10 hari sebelum menstruasi, dan hilang seiring terjadinya menstruasi disebut sebagai sindroma pramenstruasi, yang kadang-kadang dapat mengganggu produktivitas. Penyebab kondisi ini belum jelas diketahui, namun terdapat berbagai faktor yang mempengaruhi, diantaranya adalah usia menarche. Penelitian-penelitian sebelumnya menyimpulkan belum sempurnanya proses pematangan fisiologis dan psikologis sebagai faktor yang berperan. Penelitian ini ditujukan unuk mencari hubungan antara usia menarche dengan munculnya sindroma pramenstruasi pada remaja. Metode penelitian yang dilakukan adalah metode observasional analitik dengan desain potong lintang pada 191 siswi Sekolah Menengah Pertama yang sudah mengalami menstruasi, dengan menggunakan kuesioner usia menarche dan Shortened Premenstrual Assessment Form. Subyek penelitian berusia 11-15 tahun dan mengalami menarche pada usia 8-14 tahun, dibagi menjadi 2 kelompok yaitu usia menarche dini (< 10 tahun) dan usia menarche normal (> 10 tahun). Hasil menunjukkan bahwa menarche umunya terjadi pada usia 10-11 tahun (rerata 10.92). Sejumlah 62 subyek (32.5%) subyek masuk dalam kelompok usia menarche dini dan sisanya (67.5%) termasuk usia menarche normal. Gejala sindroma pramenstruasi sedang – berat (dari hasil pengisian kuesioner) didapatkan pada kelompok usia menarche dini. Uji chi kuadrat menunjukkan adanya hubungan bermakna antara usia menarche dengan munculnya sindroma pramenstruasi. Kesimpulan dari penelitian ini adalah terdapat hubungan antara usia menarche dengan sindroma pramenstruasi pada remaja.
KEJADIAN ANEMIA DAN GANGGUAN SIKLUS HAID PADA REMAJA DI CIANGSANA - NAGRAK Nirmalasari, Rully Ayu; Surjadi, Lily Marliany; Mario, Mario; Maharani, Laksmi
Jurnal Pengabdian Masyarakat Trimedika Vol. 2 No. 2 (2025)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/abdimastrimedika.v2i2.22921

Abstract

Background: Anemia in adolescents is a public health problem in Indonesia.  Based on the 2018 Basic Health Research (Riskesdas) report, Based on the 2018 Basic Health Research (Riskesdas) report, 32% of teenagers aged 15-24 years experienced anemia. The majority of teenagers who experience anemia are in the age range 10 – 18 years. Adolescent girls experiencing ongoing anemia can increase morbidity during pregnancy and childbirth. Level of knowledge, diet, nutritional status and menstrual cycle are factors that are said to influence anemia. Method: This activity was carried out in Desember 2023 and was attended by 30 young women aged 10-19 years in the Nagrak and Ciangsana district. The activity consists of several stages, namely interviews about the menstrual cycle, checking hemoglobin levels, checking nutritional status, and education about body mass index. Results: From this activity, it was found that 53.3% of teenagers had a normal body mass index, 96.7% had a normal waist/hip ratio, 50% of teenagers had irregular menstrual cycles, 80% had dysmenorrhea. Meanwhile, regarding the prevalence of anemia, 50% of adolescent girls have mild anemia and 13.3% have moderate anemia. Conclusion: The prevalence of anemia in adolescent girls in Nagrak and Ciangsana subdistricts is still high (63.3%), as are adolescents who experience irregular menstrual cycles and dysmenorrhea.
Relationships of age of menarche, frequency and duration of kunyit asam consumption and dysmenorrhea Prasetyowati, Sebrina Andri; Surjadi, Lily Marliany
Jurnal Biomedika dan Kesehatan Vol 5 No 2 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.109-115

Abstract

BACKGROUNDPuberty is intimately associated with adolescence, one of which is the first menstrual period. Young women frequently have dysmenorrhea as a result of menarche. Dysmenorrhea that isn't medicated appropriately might make it difficult for young women to go about their daily lives. Consuming kunyit asam is one solution to relieve the intensity of dysmenorrhea pain. This study aims to determine whether the consumption of kunyit asam and its regularity during menstruation can lower abdominal pain in dysmenorrhea. METHODSIn October 2021, a cross-sectional survey was conducted at the Yayasan Indocement Middle School in Bogor, West Java. Cluster random sampling was used to collect data from 108 junior high school students who completed the Form Frequency Questionnaire (FFQ) questionnaire to determine the frequency and duration of kunyit asam consumption and the Numeric Rating Scale (NRS) questionnaire to reduce the severity of dysmenorrhea pain. The Chi-Square test was used to examine the data, with the level of <0.05 as the significance level. RESULTSOf 108 respondents, most of them experienced menarche at >11 years old (90.74%), always take kunyit asam solution (57.41%) with duration >3 months (74.07%) and did not have menstrual pain (88.89%). In junior high school adolescents, a significant correlation was discovered between the frequency and the duration of kunyit asam consumption and dysmenorrhea (p=0.016, p=0.007). CONCLUSIONIn junior high school students, there is a correlation between the frequency and duration of kunyit asam consumption and dysmenorrhea. KEYWORDS: Regularity, Length, Kunyit Asam Solution, Dysmenorrhea, Teenage Girls
Pengaruh Kontrol Glikemik dengan Konversi Sputum BTA pada Pasien Diabetes Melitus dengan Tuberkulosis Septa, Della; Surjadi, Lily Marliany
Jurnal Biomedika dan Kesehatan Vol 6 No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.62-70

Abstract

Background Diabetic people have a 2-3 times higher risk of tuberculosis than non-diabetic people. Immunocompromised conditions due to diabetes increase the risk of therapeutic failure and delayed sputum conversion, which may cause by poor glycemic control. This study was conducted to determine the glycemic control effect on AFB conversion in diabetic patients with tuberculosis. Methods A cross-sectional study has been conducted on 100 diabetic patients with the new emergence of pulmonary tuberculosis. All patients were in intensive phase treatment of tuberculosis for two months at Bhayangkara R. Said Sukanto's Hospital. Data collected from medical records were random blood glucose level, percentage of random blood glucose decrement, HbA1C, and the microscopic AFB sputum smear. Fisher exact test analysis was conducted to determine the effect of random blood glucose level, percentage of blood glucose decrement and HbA1C to AFB smear results using SPSS V25.0 software for Windows with a significance level of 0.05. Results The analysis between glycemic control and AFB sputum smear conversion using random blood glucose, percentage of random blood glucose decrement and HbA1C showed a p-value of 0.000, indicating a significant relationship (p<0.05), so it showed that glycemic control affects AFB sputum smear conversion. Conclusions A significant relationship exists between glycemic control and AFB-negative conversion in patients with DM and TB. RBG showed the best sensitivity and specificity as a glycemic control parameter compared to others.
Hubungan Parameter Laboratorium dengan Derajat Klinis COVID-19 pada Kehamilan Nirmalasari, Rully Ayu; Surjadi, Lily Marliany; Maharani, Laksmi; Lisnawati, Yuyun; Mangun, Dhea
Jurnal Biomedika dan Kesehatan Vol 6 No 3 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.291-299

Abstract

Background Pregnant women were one of the most susceptible groups because they are vulnerable to respiratory infection. They may get more severe symptoms due to their physiological changes during pregnancy including the immunological response. This study was performed to find whether there is an association between laboratory parameters (Hb, leukocytes, platelet, neutrophils, lymphocyte, monocyte, NLR, PLR and CRP) and the severity of Covid-19 infection in pregnant women. Methods This study is a retrospective cohort study using secondary data from patient’s medical records at Persahabatan General Hospital, Jakarta from March to June 2021. Results Pregnancy cases with COVID-19 in this study were in the mean of 29 year age. Most of them are in the third trimester of pregnancy. 80.5% from 67 patients have no- mild symptom while 19.5% have moderate to severe symptom. There are no difference in vital sign nor oxygen saturation at first admission. Lower level was found in the parameter of leukocyte, lymphocyte and monocyte.  Neutrophil, neutrophil-to-lymphocyte ratio and C-reactive Protein increase as the degree of severity increase.  The mean neutrophil in pregnant women with moderate to severe COVID-19 symptom was 80.49±7.47 while median NLR value was of 6.76 (2.73-18.71) . Conclusions Neutrophil, neutrophil-to-lymphocyte ratio and C-reactive Protein has associate significantly to severity symtomps of COVID-19 in pregnancy.
Hubungan Usia Menarche dengan Kejadian Kanker Payudara pada Wanita Dewasa Balgahoom, Najwa; Surjadi, Lily Marliany; Kurniawan, Febriyanto
Jurnal Biomedika dan Kesehatan Vol 8 No 3 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Breast cancer is a non-communicable disease that is a health problem worldwide. Based on breast cancer prevalence data according to the World Health Organization (WHO) in 2020, 2.3 million women have been diagnosed, and 685,000 of them have died from breast cancer. There are several factors that can increase the risk of possible breast cancer incidence, some of which are age of menarche, nulliparity (never giving birth), and obesity. The purpose of this study was to determine the relationship between age at menarche, body mass index (BMI), and nulliparity with the incidence of breast cancer in adult women. Methods: This cross-sectional study was conducted at Dharmais Cancer Hospital, Jakarta, with 104 respondents aged 19-59 years with breast complaints in the period March-May 2024. By excluding respondents with consecutive non-random sampling techniques. Data analysis using the Mann-Whitney test with a probability level (p < 0.05). Results: The results showed that 98 respondents had breast cancer, and >80% of them had the no special type (NST) breast cancer. While 6 other respondents were not diagnosed with breast cancer. There were 62 respondents with normal menarche age (>12 years), with a p-value = 0.979. There were 91 respondents with multiparity, with a p-value = 0.891. In addition, 74 respondents had excessive body mass index (BMI), with a p-value = 0.336. Conclusions Based on statistical analysis, it can be concluded that there is no significant relationship between menarche age, body mass index (BMI), and parity with breast cancer in adult women. Keywords: Breast cancer, menarche age, body mass index (BMI), nulliparity.
Co-Authors Balgahoom, Najwa Inshira, Feysha Nazla Kurniawan, Febriyanto Laksmi Maharani Lisnawati, Yuyun Mangun, Dhea Mario Mario Prasetyowati, Sebrina Andri Rachmiyani, Irmiya Rully Ayu Nirmalasari, Rully Ayu Septa, Della Yudhisman Imran, Yudhisman