Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Jurnal Fitofarmaka Indonesia

fitofarmakaindo
Website

Published by Universitas Muslim Indonesia

ISSN : 23560398 EISSN : 25412329 DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology

Jurnal Fitofarmaka Indonesia merupakan salah satu jurnal yang dikelola oleh Laboratorium Farmakognosi-Fitomikia Fakultas Farmasi Universitas Muslim Indonesia yang terbit pertama kali pada bulan Januari 2014. Jurnal Fitofarmaka Indonesia merupakan jurnal ilmiah yang terbit secara on-line dan cetakan serta menerbitkan artikel atau karya ilmiah hasil penelitian dalam bidang obat bahan alam.

Arjuna Subject : -

Articles 5 Documents

Search results for , issue "Vol 7, No 1 (2020): JURNAL FITOFARMAKA INDONESIA" : 5 Documents clear

Pengembangan Mikrogranul Mukoadhesif Ekstrak Kayu Manis Dengan Kombinasi Polimer Karbopol Dan Gelatin Sri Wardatun; Erni Rustiani; Opi Damahyanti
Jurnal Fitofarmaka Indonesia Vol 7, No 1 (2020): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Senyawa bahan alam umumnya memiliki kelarutan yang rendah dan absorpsi yang lemah dalam tubuh. Pengembangan formula mikrogranul mukoadhesif dari ekstrak kayu manis dengan polimer karbopol dan gelatin bertujuan untuk meningkatkan kelarutan dan absorpsi ekstrak kayu manis dalam tubuh. Pada penelitian ini, mikrogranul mukoadhesif diformulasikan menggunakan ekstrak kayu manis dengan tiga formulasi yang berbeda yaitu penggunaan karbopol 934 P 5%: gelatin tipe B 4% (F1), karbopol 934P 5%: gelatin tipe B 5% (F2) dan karbopol 934 5%: gelatin tipe B 6% (F3). Hasil penelitian menunjukkan bahwa kombinasi karbopol 934P 5%: gelatin tipe B 5% (F2)merupakan formulasi mikrogranul mukoadhesif yang menghasilkan kadar asam sinamat paling tinggi setelah uji wash off menggunakan jaringan lambung (6,48%) dan usus tikus (55,21%). Hasil evaluasi fisik terhadap mikrogranul meliputi uji sudut diam, kadar air, laju alir granul, uji wash off, morfologi dan ukuran partikel menunjukkan bahwa mikrogranul mukoadhesif dari F2 menghasilkan kualitas granul paling baik.

Uji Aktivitas Antiplasmodium Dari Isolat Kulit Batang Kayu Tammate (Lannea coromandelica Houtt. Merr.) Secara In-Vitro Karlina Amir Tahir; Haeria Haeria; Alifia Putri Febriyanti; St. Chadijah; Nursalam Hamzah
Jurnal Fitofarmaka Indonesia Vol 7, No 1 (2020): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

One of the main causes of death and a major public health problem is malaria. Some drug resistance and the limited number of effective drugs have given the community a sense of worry. This makes the discovery of new antimalarial compounds very necessary. Based on the results of exploration of natural materials, Javanese wood is one of the plants that is efficacious as an antimicrobial and is thought to be efficacious as antiplasmodium. This study was then conducted to find hexan and ethyl acetate isolates from the Java wood fraction (Lannea coromandelica Houtt. Merr.) Which effectively inhibited the development of Plasmodium falciparum in vitro. This research is a follow-up study from previous studies in testing the fraction of Javanese bark against antioxidant activity. The procedure starts from hexan and ethyl acetate isolates with five concentrations of 10 (µg / ml), 1 (µg / ml), 0.1 (µg / ml), 0.01 (µg / ml) and 0.001 (µg / ml) 3D7 strain of Plasmodium falciparum was measured based on the average percent resistance. The results of this study indicate that etil asetat isolate have IC50 2,727 µg/ml, its mean moderate activity as antiplasmodium. While hexan isolate have IC50 >10 µg/ml its mean not have or low antiplasmodium activity.

Pengembangan Sediaan Serbuk Antidiabetes dari Kombinasi Ekstrak Kulit Buah Manggis (Garcinia Mangostana L.) dan Ekstrak Daun Salam (Syzygium polyanthum (Wight) Walp.) Rizki Yulianti; Partomuan Simanjuntak; Anny Victor Purba
Jurnal Fitofarmaka Indonesia Vol 7, No 1 (2020): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Diabetes mellitus is a metabolic disease characterized by hyperglicemic. Mangosteen (Garcinia mangostana L.) and Salam (Syzygium polyanthum (Wight) Walp.) are plants which recognized as blood glucose controller. The study aims to determine the effectiveness of the combination of the two extract in decreasing blood sugar levels of diabetic rats. The rats divided into 6 groups: group I (normal control) without treatment, group II (negative control), group III (positive control), group IV (extract of mangosteen with dose of 400 mg), group V (extract of salam leaf with dose of 400 mg) and group VI (combination of mangosteen 200 mg and salam leaf 200 mg). Data were analyzed by One-Way Anova, followed by PostHoc Bonferroni analysis. Then the combination of the extract was formulated in powder dosage form blended with PVP, Sucralose and Lactose. The evaluation included physical test are organoleptic, water content and flowability time. The results showed that the combination of the extracts of mangosteen and salam leaf comprising half doses of eact extract could lower blood glucose levels significantly (P<0.05) with better efficacy than each single extract and the combination of extracts able to produce powder dosage form with the requirement (organoleptic, water content and flowability time).

Potensi Ekstrak Buah Buni (Antidesma bunius (L) Spreng) Sebagai Inhibitor Enzim α-Glukosidase La Hamidu; Partomuan Simanjuntak; Rizna Triana Dewi
Jurnal Fitofarmaka Indonesia Vol 7, No 1 (2020): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Diabetes mellitus is still a global health problem that continues to increase rapidly and become one of the major metabolic diseases throughout the world. This study aims to determine the potential of Buni fruit as an α-glucosidase inhibitor. α-glucosidase inhibition test is carried out on a blank solution (test solution without sample/standard), acarbose solution as a comparison standard and samples are carried out in accordance with the optimization conditions obtained. The rendemen percent of green and red buni fruit extract yields are 6.35% and 3.09%, respectively. The results of the identification of secondary metabolites using TLC showed that green and red buni fruit extract contains flavonoid, phenolic and alkaloid compounds. The results of the α-glucosidase enzyme inhibition test showed that the red buni fruit extract had the highest activity compared to green buni fruit extract with an IC50 value of 85.27 ppm.

Pengembangan Ekstrak Etanol Limbah Biji Pepaya (Carica papaya L.) Sebagai Serum Antijerawat Andi Hasrawati; Hardianti Hardianti; Adisti Qama; Muhammad Wais
Jurnal Fitofarmaka Indonesia Vol 7, No 1 (2020): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Acne or commonly called acne vulgaris merupahkan abnormalities in the skin that almost everyone has experienced it. Acne is a problem of skin, neck, chest, and back that occurs in times of skin-the skin of the skin will be clogged by excessive fat deposits. Propionibacterium acnes is a gram-positive bacteria as part of normal flora and fauna. Papaya seeds are agricultural waste that has antibacterial activity against the bacteria Propionibacterium acnes with a very low cost. One of the proper acts for acne problem is by using serum. Serum has a very fast absorptive effect to penetrate the inner skin without the effects of sticky effects on the skin. By knowing that the bacteria Propionibacterium acnes can cause acne that can attack various circles and know the benefits of papaya seeds that inhibit the growth of acne-causing bacteria, it is necessary to formulate papaya seed estrak as antijerawat, so this process formulates the serum preparation of papaya seed estrak which can as pen prevent the growth of acne-causing bacteria. The research method that will be done is the initial processing of the sample by extraction and then proceed with formulation of the preparation. After that, the evaluation of serum preparation and antibacterial activity test are available on the preparation.

Page 1 of 1 | Total Record : 5

Filter by Year

2020 2020

Filter By Issues

All Issue Vol 12, No 1 (2025): JURNAL FITOFARMAKA INDONESIA Vol 11, No 3 (2024): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION) Vol 11, No 2 (2024): JURNAL FITOFARMAKA INDONESIA Vol 11, No 1 (2024): JURNAL FITOFARMAKA INDONESIA Vol 10, No 3 (2023): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION) Vol 10, No 2 (2023): JURNAL FITOFARMAKA INDONESIA Vol 10, No 1 (2023): JURNAL FITOFARMAKA INDONESIA Vol 9, No 3 (2022): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION) Vol 9, No 2 (2022): JURNAL FITOFARMAKA INDONESIA Vol 9, No 1 (2022): JURNAL FITOFARMAKA INDONESIA Vol 8, No 3 (2021): JURNAL FITOFARMAKA INDONESIA Vol 8, No 2 (2021): JURNAL FITOFARMAKA INDONESIA Vol 8, No 1 (2021): JURNAL FITOFARMAKA INDONESIA Vol 7, No 3 (2020): JURNAL FITOFARMAKA INDONESIA (English Edition) Vol 7, No 2 (2020): JURNAL FITOFARMAKA INDONESIA Vol 7, No 1 (2020): JURNAL FITOFARMAKA INDONESIA Vol 6, No 2 (2019): JURNAL FITOFARMAKA INDONESIA Vol 6, No 1 (2019): JURNAL FITOFARMAKA INDONESIA Vol 5, No 2 (2018): JURNAL FITOFARMAKA INDONESIA Vol 5, No 1 (2018): JURNAL FITOFARMAKA INDONESIA Vol 4, No 2 (2017): JURNAL FITOFARMAKA INDONESIA Vol 4, No 1 (2017): JURNAL FITOFARMAKA INDONESIA Vol 3, No 2 (2016): JURNAL FITOFARMAKA INDONESIA Vol 3, No 2 (2016): JURNAL FITOFARMAKA INDONESIA Vol 3, No 1 (2016): JURNAL FITOFARMAKA INDONESIA Vol 2, No 2 (2015): JURNAL FITOFARMAKA INDONESIA Vol 2, No 1 (2015): JURNAL FITOFARMAKA INDONESIA Vol 1, No 2 (2014): JURNAL FITOFARMAKA INDONESIA Vol 1, No 1 (2014): JURNAL FITOFARMAKA INDONESIA More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota makassar,

Sulawesi selatan

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

Contact Email -

Phone -

Journal Mail Official -

Editorial Address -

Location Kota makassar, Sulawesi selatan INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota makassar,

Sulawesi selatan

INDONESIA