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All Journal Jurnal Fitofarmaka Indonesia As-syifaa Jurnal Farmasi JURNAL PENGABDIAN KEPADA MASYARAKAT Jurnal Ilmiah Farmako Bahari Journal of Pharmaceutical and Health Research Jurnal Kesehatan Tambusai Nusantara Hasana Journal JURNAL PENGABDIAN MASYARAKAT YAMASI Jurnal Kesehatan Cendikia Jenius MPSJ

A Hasrawati

Fakultas Farmasi Universitas Muslim Indonesia

Author-ID : 4388750

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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FORMULASI DAN EVALUASI SALEP EKSTRAK DAUN GULMA SIAM (Chromolaena odorata L.) DENGAN VARIASI BASIS SALEP Hasrawati, A.; Famir, Yasir; Aztriana, Aztriana; Mursyid, A. Mumtihanah
Jurnal Ilmiah As-Syifaa Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Siam weed leaves are one of the plants that function as wound medicine. This study aims to produce a stable ointment dosage form. Siamese weed leaf extract is formulated in the form of ointment with a variety of bases consisting of a hydrocarbon base, absorption, water soluble and emulsion. Evaluation of physical stability includes organoleptic testing, homogeneity, pH, dispersion, viscosity and flow properties carried out before and after forced conditions. Forced conditions were carried out with stock storage for 10 cycles at 50 and 350. The results of the analysis showed that the viscosity of the preparations in all formulas changed after storage at 50 and 350 for 5 days. However, the statistical results show that all formulas did not experience significant changes between before and after the stress condition treatment.

AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN KELOR (Moringa oleifera L.) DAN PENGEMBANGANNYA MENJADI BENTUK SEDIAAN GEL Asisi, Nur; Uliyah, Uliyah; Amaliyah, Nurul Fitrah; Hasrawati, A
Jurnal Ilmiah As-Syifaa Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i1.682

Antioxidants are used to prevent the oxidation of free radical compounds which have a bad impact on the body, including the skin.Â One source of antioxidants derived from natural ingredients is Moringa leaves.Â Moringa leaves have a number of benefits due to the many active chemical compounds.Â The antioxidant activity of Moringa leaves can be optimized by developing Moringa leaves into a gel dosage form.Â A literature review regarding the compound content and activity of Moringa leaves was carried out to obtain scientific data that can be used in the development of Moringa leaves as an antioxidant.Â Narrative review with data sources from Science Direct, Pubmed, CiterSeerX, and Google Scholars. The Inclusion and exclusion criteria were set to obtain literature according to the scope of the study.Â The results of the literature review showed that Moringa leaves contain the main active compounds of polyphenols and flavonoids which have strong antioxidant activity.Â Gel dosage form is one of the best choices to optimize the antioxidant activity of Moringa leaves.Â HPMC, carbopol and xanthan gum are gelling agent was produced a gel preparation with good pharmaceutical characteristics.

Pengembangan Ekstrak Etanol Limbah Biji Pepaya (Carica papaya L.) Sebagai Serum Antijerawat Andi Hasrawati; Hardianti Hardianti; Adisti Qama; Muhammad Wais
Jurnal Fitofarmaka Indonesia Vol 7, No 1 (2020): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Acne or commonly called acne vulgaris merupahkan abnormalities in the skin that almost everyone has experienced it. Acne is a problem of skin, neck, chest, and back that occurs in times of skin-the skin of the skin will be clogged by excessive fat deposits. Propionibacterium acnes is a gram-positive bacteria as part of normal flora and fauna. Papaya seeds are agricultural waste that has antibacterial activity against the bacteria Propionibacterium acnes with a very low cost. One of the proper acts for acne problem is by using serum. Serum has a very fast absorptive effect to penetrate the inner skin without the effects of sticky effects on the skin. By knowing that the bacteria Propionibacterium acnes can cause acne that can attack various circles and know the benefits of papaya seeds that inhibit the growth of acne-causing bacteria, it is necessary to formulate papaya seed estrak as antijerawat, so this process formulates the serum preparation of papaya seed estrak which can as pen prevent the growth of acne-causing bacteria. The research method that will be done is the initial processing of the sample by extraction and then proceed with formulation of the preparation. After that, the evaluation of serum preparation and antibacterial activity test are available on the preparation.

PENGEMBANGAN FORMULASI MIKROEMULSI MINYAK SEREH (Cymbopogon nardus) MENGGUNAKAN EMULGATOR SURFAKTAN NONIONIK A Hasrawati; Nursiah Hasyim; Nur Alif Irsyad
Jurnal Fitofarmaka Indonesia Vol 3, No 1 (2016): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Citronella oil (Cymbopogon nardus) is an essential oil which useful as an antibacterial that is usuallyprovided in the form of macroemulsion for topical use. absorption of macroemulsion through the skin relatively low, thermodynamically is not stable and can produce a separate phase in the storage period. The one of development emulsion system to get better characteristics is to form a microemulsion. Microemulsion is an oil and water dispersion stable thermodynamically stabilized by surfactants and in some cases a cosurfactant. The objective of this study was to formulatecitronella oil in the form of a stable microemulsion using nonionic surfactant. Optimization of the type and amount of emulsifier (surfactant) was required to formulate a stable microemulsion. In this study, microemulsion was evaluated during a month. Type and concentration of surfactant, cosurfactant, Citronella oil (Cymbopogon nardus) and water was optimized. A stable citronella oil microemulsion was successfully created with composition of 15% PEG 400 as cosurfactant, 15% tween 80 as surfactant, 2-4% Citronella oil as oil phase and 10% glycerin as humectant and distilled water as aqueous phase. From the observation, microemulsion formula has clear appearance but physically unstable during a month storage

PENGEMBANGAN GEL EKSTRAK ETANOL CABAI RAWIT (Capsicum frutescence L) A. Hasrawati; Aztriana Aztriana
As-Syifaa Jurnal Farmasi Vol 8, No 1 (2016): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Chili Pepper (Capsicum frutescence L) is a plant that can be used for the treatment of rheumatoid arthritis (RA). Chemical constituents contained in chili pepper is capsaicin, it was stimulate the nerves that can relieve pain. The purpose of this study was to determine the gel formulation of the ethanol extract of cayenne pepper which has optimal stability by using a variation of the base. In this study, the ethanol extract of cayenne pepper (2.5%) was made using synthetic gel base (carbopol) and semisynthetic gel base (sodium carboxymethylcellulose). Evaluation of the physical stability was tested using stress conditions method. The stability parameters were determined by organoleptic, viscosity and flow type. The ethanol extract of chili pepper was successfully created gel form by using 5% of sodium carboxymethylcellulose and 1% of carbopol as a gelling agent. There was no significant change of two formulas in stability evaluation before and after of the storage condition.

SEDIAAN KRIM EKSTRAK AIR BUAH AREN (Arenga pinnata) SEBAGAI ANTIOKSIDAN Riny Erfiah Rinda; A. Mumtihanah Mursyid; A. Hasrawati
As-Syifaa Jurnal Farmasi Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Palm fruit (Arenga pinnata) contains galactomannan which has the potential as an antioxidant activity with an IC50 value of 20,45 ppm. This study aims to produce cream dosage forms with antioxidant activity using the scaverry DPPH radical scavenger method from arenga pinnata water extract. Palm fruit water extract is formulated in cream form with variations in the concentration of stearic acid and triethanolamine emulgators in F1 (6:4), F2 (7:3), and F3 (8:2). Evaluation of physical stability includes organoleptic testing, homogeneity, pH, emulsion type, viscosity and type of flow carried out before and after forced conditions. In the statistical analysis of viscosity, the results of each formula showed no significant changes both before and after the conditions were forced. The results of the study obtained formula 2 and formula 3 has optimal stability. The stable formula was then tested for antioxidants using the DPPH (1,1-Diphenyl-2-Picrylhydrazyl) radical scavenger method. Formula 2 and formula 3 each yield a DPPH radical inhibition percentage of 65% and 48.04%.

AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN KELOR (Moringa oleifera L.) DAN PENGEMBANGANNYA MENJADI BENTUK SEDIAAN GEL Nur Asisi; Uliyah Uliyah; Nurul Fitrah Amaliyah; A. Hasrawati
As-Syifaa Jurnal Farmasi Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i1.757

Antioxidants are used to prevent the oxidation of free radical compounds which have a bad impact on the body, including the skin. One source of antioxidants derived from natural ingredients is Moringa leaves. Moringa leaves have a number of benefits due to the many active chemical compounds. The antioxidant activity of Moringa leaves can be optimized by developing Moringa leaves into a gel dosage form. A literature review regarding the compound content and activity of Moringa leaves was carried out to obtain scientific data that can be used in the development of Moringa leaves as an antioxidant. Narrative review with data sources from Science Direct, Pubmed, CiterSeerX, and Google Scholars. The Inclusion and exclusion criteria were set to obtain literature according to the scope of the study. The results of the literature review showed that Moringa leaves contain the main active compounds of polyphenols and flavonoids which have strong antioxidant activity. Gel dosage form is one of the best choices to optimize the antioxidant activity of Moringa leaves. HPMC, carbopol and xanthan gum are gelling agent was produced a gel preparation with good pharmaceutical characteristics.

FORMULASI GEL EKSTRAK ETANOL DAUN SIRIH CINA SERTA AKTIVITASNYA TERHADAP PERTUMBUHAN BAKTERI PENYEBAB JERAWAT Propionibacterium acne DAN Staphylococcus aureus Ulfah Ayu Ninsih; Andi Tenri Bunga Lambogo; Ernawati Ernawati; Mutiara Imaniar; A. Hasrawati
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i1.784

Pepper elder is a weed plant whose leaves contain anti-bacterial compounds such as flavonoids, tannins, triterpenoids, and saponins that can be used as acne treatment therapy. Pepper elder leaves can be made into anti-acne gel preparations by formulating the right gelling agent. This study aims to obtain a gel with good physical stability from variations in the gelling agent base and its activity against acne-causing bacteria. Formulation of Pepper elder leaf extract gel is made with variations in the base of Na.CMC, Carbopol, and HPMC, further stability evaluation includes organoleptic, homogentias, pH, viscosity, scattering power, and testing of antibacterial activity against the growth of Propionibacterium acne and Staphylococcus aureus. The results obtained from the stability test obtained by the Carbopol base and HPMC have good standards for organoleptics, homogenity, pH, viscosity, and scattering power. Antibacterial testing showed clear zone diameters formed against Propionibaceterium acne in naCMC, Carbopol, and HPMC variations of 17.7 mm, 16.3 mm, and 21.3 mm and staphylococcus aureus of 13.3 mm, 15.3 mm, and 14.3 mm, respectively. Based on the results obtained, HPMC gel has the best gel stability and can all formulas inhibit the growth of acne-causing bacteria Propionibacterium acne and Staphylococcus aureus evidenced by the diameter of the bland zone formed into the strong category.

FORMULASI KRIM ANTIHIPERPIGMENTASI EKSTRAK BIJI BUAH LENGKENG (Euphoria longan [Lour]) Vina Purnamasari; A. Hasrawati; Aztriana Toha
Jurnal Ilmiah Farmako Bahari Vol 11, No 1 (2020): Jurnal Ilmiah Farmako Bahari
Publisher : Fakultas MIPA Universitas Garut

Proses hiperpigmentasi melibatkan aktivitas suatu enzim, yaitu tirosinase. Salah satu tanaman yang berfungsi sebagai antihiperpigmentasi adalah biji buah lengkeng karena mengandung asam galat, glikosida flavon, dan hidroksinamat dengan kandungan utama flavon dimana asam galat memiliki aktivitas sebagai inhibitor enzim tirosinase. Penelitian ini bertujuan untuk mendapatkan suatu formula krim antihiperpigmentasi ekstrak biji buah lengkeng (Euphoria longan [Lour]) yang stabil dan memiliki sifat farmaseutik yang baik berdasarkan evaluasi kestabilan serta tidak mengiritasi kulit. Desain penelitian yang digunakan adalah penelitian eksperimental laboratorium. Krim antihiperpigmentasi dengan variasi konsentrasi bahan pengemulsi Triethanolamin dan Asam Stearat dibuat dalam 2 formula. Formula 1 dengan konsentrasi Triethanolamin : Asam Stearat sebesar 2% : 6% dan formula 2 sebesar 3% : 9%. Hasil penelitian pada kedua formula menunjukkan bahwa pada pengujian organoleptik tidak mengalami perubahan bau, warna dan konsistensi sebelum dan sesudah kondisi dipaksakan, pada pengukuran pH menujukkan bahwa kedua formula memiliki pH yang sama yaitu pH 7 sebelum kondisi dipaksakan dan pH 7,9 sesudah kondisi dipaksakan, pada pengujian homogenitas menunjukkan formula homogen, pada pengujian tipe emulsi menunjukkan bahwa kedua formula mempunyai tipe emulsi m/a sebelum dan sesudah kondisi dipaksakan, pada pengujian daya sebar menunjukkan peningkatan daya sebar, Reogram kedua formula menunjukkan aliran plastis dan pada pengujian iritasi menunjukkan tidak terjadi iritasi baik iritasi primer maupun iritasi sekunder. Kesimpulan dari penelitian ini bahwa ekstrak biji buah lengkeng dapat dibuat dalam bentuk krim antihiperpigmentasi yang memenuhi pengujian kestabilan farmaseutik namun formula 2 menunjukkan kestabilan yang optimal dan sifat farmaseutik yang baik dibandingkan formula 1. Selain itu penggunaan 1% esktrak tidak mengiritasi kulit sehingga aman digunakan pada kulit.

Pemberdayaan Masyarakat di Desa Pucak dalam Pemanfaatan Tanaman Herbal Sebagai Gel Antiseptik A. Hasrawati; Iskandar Zulkarnain; Aztriana Aztriana
JURNAL PENGABDIAN KEPADA MASYARAKAT Vol 12, No 1 (2022): Juli 2022
Publisher : LPPM UNINUS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30999/jpkm.v12i1.1496

Maintaining hand hygiene is one of the most important steps to minimize the spread of disease from viruses and bacteria. But in reality there are still many people who are lazy to do it. In fact, the hands are one of the entrances for germs to enter the body. The use of antiseptics is an effort made to prevent disease transmission other than washing with soap. The practical use of hand sanitizer is a solution to keep hands clean anytime and anywhere. Natural ingredients are one of the right choices in making antiseptics because of the active chemical components that can fight bacteria or viruses, including piper betel leaf and orange peel. The chemical content of piper betel leaf and orange peel has anti-bacterial activity. This service activity aims to provide knowledge about training in making antiseptic gels from herbs, namely with the main ingredients of piper betel leaf and orange peel in partner groups in Pucak village, Bontonompo sub-district, Maros district. The community service activity was carried out in the form of training by providing materials and practices for the use of natural basic ingredients as an effort to make antiseptic gels made from herbs

Co-Authors A. Mumtihanah Mursyid A. Mumtihanah Mursyid, A. Mumtihanah AA Sudharmawan, AA Adisti Qama Aliefia, Nur Amaliyah, Nurul Fitrah Andi Tenri Bunga Lambogo Asisi, Nur Aztriana Aztriana Aztriana Aztriana, Aztriana Azzahra, Jihan Bade, Iskandar Zulkarnain Mahmud Damras, Anggi Aprianti Dian Safitri Achmad Dwi Kurnia Aslam Ernawati Ernawati Famir, Yasir Hamka, Nurhafizah haq, Nasrul Hardianti Hardianti Harliman, Isrhopana Kinana Hokilia, Resky Nov Iksan, Muh. Indah Permatasari Iskandar Zulkarnain Jaya, Taufiq Mirawati Mirawati Mudafar, Wildan Muhammad Wais Muris, Dian Indri Mutiara Imaniar Nur Alif Irsyad Nur Asisi Nurlina Nurlina Nurlina Nurlina Nursiah Hasyim Nurul Fitrah Amaliyah Rahmat Kosman Reski Awalia Riny Erfiah Rinda Ririn Ririn Rusli SAFITRI, INDAH DIAN Sahira, Sahira Sitti Amirah Sri Julyani sukmawati Tengku Riza Zarzani N Ulfah Ayu Ninsih Uliyah Uliyah Uliyah, Uliyah Vina Purnamasari M Vina Purnamasari M, Vina

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