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INDONESIA
Jurnal Fitofarmaka Indonesia
Published by Universitas Muslim Indonesia
ISSN : 23560398     EISSN : 25412329     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology
Jurnal Fitofarmaka Indonesia merupakan salah satu jurnal yang dikelola oleh Laboratorium Farmakognosi-Fitomikia Fakultas Farmasi Universitas Muslim Indonesia yang terbit pertama kali pada bulan Januari 2014. Jurnal Fitofarmaka Indonesia merupakan jurnal ilmiah yang terbit secara on-line dan cetakan serta menerbitkan artikel atau karya ilmiah hasil penelitian dalam bidang obat bahan alam.
Arjuna Subject : -
Articles 5 Documents
 1 
Search results for , issue "Vol 9, No 2 (2022): JURNAL FITOFARMAKA INDONESIA" : 5 Documents clear
Formulasi Sediaan Serum Anti Aging dengan Kombinasi dari Ekstrak Buah Tomat (Lycopersicum esculentum L.) dan Ekstrak Kulit Buah Semangka (Citrullus lanatus Thunb.) Rima Apria Purwanti; Yunahara Farida; Shelly Taurhesia
Jurnal Fitofarmaka Indonesia Vol 9, No 2 (2022): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i2.864

Abstract

Aging is a problem for everyone, especially those who have entered middle age and above. Aging can be caused by various factors, namely factors that come from within the body and from outside the body. One of the extrinsic factors were sun exposure, temperature / humidity and free radicals. Skin aging is mostly caused by free radicals, one of which is sunlight radiation. This study aims to produce a serum preparation that functions as an antioxidant with a combination of tomato extract and watermelon rind. The antioxidant activity of tomato extract, watermelon rind extract and combination extract was carried out using the DPPH method, then the anti aging serum was formulated using hydroxy ethyl cellulose, glycerin, DMDM hydantoin, ethoxy diglycol and aqua DM. Evaluation of serum preparations includes physical evaluation (organoleptic examination, dispersibility, homogeneity, viscosity, irritation test), chemistry (pH), and microbiology. Data were analyzed using one way Anova, the results differed significantly when the p-value was less than 0.05 (p <0.05). The results showed that the combination extract had a better IC50 value of 59.19 ppm, tomato extract 69.89 ppm, watermelon rind extract 79.29 ppm. Combined serum preparation at F1 (T: S / 1: 1) IC50 value was 97.37 ppm, F2 (T: S / 1: 2) 80.70 ppm, F3 (T: S / 2: 1) 69.81 ppm so it is included in the category of strong antioxidants.
Aktivitas Penyembuhan Luka Infeksi Krim Kombinasi Daun Sirsak (Annona muricata L.) Dan Daun Sirih (Piper betle L.) Dengan Bakteri Staphylococcus aureus Pada Punggung Kelinci New Zealand White Secara In Vivo Indah Ana Resti; Dwi Ningsih
Jurnal Fitofarmaka Indonesia Vol 9, No 2 (2022): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i2.879

Abstract

Several types of tropical plants in Indonesia that contain anti-bacterial chemical compounds such as tannins, flavonoids and saponins, namely betel (Piper betle L.) leaves and soursop (Annona muricata L.) leaves. Objectives of the research was to determine activity of cream from soursop (Annona muricata L.) leaves ethanol extract and betel (Piper betle L.) leaves ethanol extract on the backs of rabbits infected with Staphylococcus aureus bacteria. In addition, the research conducted could also determine the stability of cream that produced and its pharmacological effects. Data analysis technique using ANOVA method, significance value did not reach 0.05. Extraction process using 70% ethanol as solvent with extraction method, namely maceration. Parameters of cream preparation were from level of storage duration for 0 days and concentration used. Then the level of cream preparation effectiveness in wounds healing could be seen from observations of wounds and pus drying time as well as edema and erythema loss. Cream preparation from combination of soursop (Annona muricata L.) leaves ethanol extract and betel (Piper betle L.) ethanol extract in formula 6 with concentration ratio of 10%: 12.5%, resulted better and faster healing rate against Staphylococcus aureus infection than other formulas. Required recovery time interval was 10 days and cream preparation had good stability.
Standarisasi Ekstrak Etanol Buah Bintaro (Cerbera odollam Gaertn.) Sebagai Obat Tradisional Rezki Amriati Syarif; Virsa Handayani; Alfirah Angraeni
Jurnal Fitofarmaka Indonesia Vol 9, No 2 (2022): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i2.592

Abstract

This research was conducted with the aim of examining the utilization of bintaro fruit extract (Cerbera odollam Gaertn.) as a traditional medicine that meets quality standards, so that the extract standardization process was carried out by determining specific and non-specific parameters.Based on the enormous potential of the Bintaro plant as a natural ingredient that can be used as traditional medicine, it is necessary to standardize the Bintaro fruit extract to determine the quality and safety of the extract raw materials used to support health. The research was conducted by determining the standardization of data on the determination of specific and non-specific parameters. The specific parameters that have been carried out include the identity of the extract, organoleptic test, the content of water soluble compounds 19.7%, the content of ethanol soluble compounds 6.96%, the content of positive extract compounds containing alkaloids, flavonoids, terpenoids, tannins and saponins. Non-specific parameters that have been carried out include drying shrinkage of 0.197%, moisture content of 2.124%, total ash content of 3.65%, acid soluble ash content of 1.3%, metal contamination of Pb and Cd 0.02 µg/g, microbial contamination of ALT bacteria. 0 colonies and 20 colonies of yeast. The results of the study met the standardization of extract quality.The data that will be obtained is expected to be additional information about the ethanolic extract of bintaro fruit (Cerbera odollam Gaertn.) that meets quality standards as traditional medicine, so as to maintain consistency and uniformity of efficacy and keep active compounds consistently measurable between treatments, and can maintain safety on consumers.
Aktivitas Iron Chelator Ekstrak Etanol Dan Fraksi Daun Putri Malu (Mimosa pudica L) Terhadap Pasien Thalasemia Menggunakan Metode Fic (Ferrous Ion Chelating) M. Wahyu Ariawan; Ana Indrayati; Supriyadi Supriyadi
Jurnal Fitofarmaka Indonesia Vol 9, No 2 (2022): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i2.838

Abstract

Thalasemia merupakan penyakit genetik yang disebabkan oleh defisiensi rantai globin α dan β yang menyusun hemoglobin. Penelitian ini bertujuan untuk mengetahui adanya kandungan senyawa mimosin dan konsentrasi optimum mimosin pada tanaman Mimosa pudica L sebagai agen pengkhelat besi pada pasien thalasemia secara in-vitro. Penelitian diawali dengan melakukan ekstraksi dan fraksinasi daun putri malu selanjutnya menguji kadar feritin menggunakan uji Ferrous Ion Chelating (FIC). Pengujian dilakukan sebanyak tiga kali. Selanjutnya dihitung kadar feritin dengan ELISA reader. Tahap akhir, yaitu mengukur kadar mimosin. Mimosin dengan konsentrasi 500 ppm memiliki aktivitas pengkhelat besi dengan persentase penurunan kadar feritin sebesar 84,48%.  Fraksi n-heksan dengan  konsentrasi  500 ppm memiliki aktivitas pengkhelat besi dengan penurunan aktivitas feritin sebesar 81,27%.
Uji Aktivitas Antibateri Ekstrak Etanol Daun Kenikir (Cosmos caudatus kunth.) Terhadap Staphylococcus aureus Maulana Tegar AdityaNugraha; Kiki Siti Fatimah; Dwi Larasati; Ferli Eko Kurniantoro
Jurnal Fitofarmaka Indonesia Vol 9, No 2 (2022): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i2.861

Abstract

Infeksi bakteri dapat terjadi pada manusia dan menyerang berbagai sistem organ pada tubuh, antara lain infeksi saluran pernapasan, infeksi kulit, infeksi saluran pencernaan, dan infeksi saluran urinarius. Bakteri penyebab infeksi kulit antara lain disebabkan oleh Staphylococcus aureus. Salah satu tanaman yang berkhasiat sebagai antibakteri yaitu daun kenikir (Cosmos caudatus Kunth.) karena mengandung senyawa aktif berupa minyak atsiri, steroid, tanin, flavonoid, dan alkaloid. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri dan konsentrasi minimum ekstrak etanol daun kenikir (Cosmos caudatus Kunth.) yang menunjukkan aktivitas antibakteri terhadap Staphylococcus aureus. Jenis penelitian ini adalah penelitian eksperimental, dengan menggunakan  metode difusi sumuran dan diameter zona hambat. Konsentrasi ekstrak etanol daun kenikir yang digunakan pada penelitian ini adalah 20%, 30%, dan 40%. Uji dilakukan untuk mengamati ada tidaknya zona hambat dari ekstrak daun kenikir (Cosmos caudatus Kunth.) terhadap Staphylococcus aureus, setelah 24 jam inkubasi. Analisis yang digunakan adalah analisis deskriptif. Hasil penelitian menunjukkan ekstrak etanol daun kenikir (Cosmos caudatus Kunth.) dengan konsentrasi 20%, 30%, dan 40% dapat menghambat pertumbuhan bakteri Staphylococcus aureus dengan rerata masing-masing 14,11mm, 14,86mm, dan 16,05mm dari hasil peneltian konsentrasi 40% esktrak etanol daun kenikir memiliki aktivitas terbaik dalam penghambatan pertumbuhan bakteri Staphylococcus aureus

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