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All Journal Jurnal Fitofarmaka Indonesia As-syifaa Jurnal Farmasi Jurnal Review Pendidikan dan Pengajaran (JRPP) Pharmaceutical Sciences and Research (PSR) Jurnal Farmasi Indonesia Celebes Journal of Community Services Jurnal Sains dan Kesehatan Makassar Natural Product Journal MPSJ
Virsa Handayani
Universitas Muslim Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Social Sciences Other

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IDENTIFIKASI MAKROSKOPIK DAN MIKROSKOPIK SEDIAAN JAMU ASAM URAT YANG BEREDAR DI KOTA MAKASSAR Handayani, Virsa
Jurnal Ilmiah As-Syifaa Vol 3, No 1 (2011): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v3i1.125

Abstract

Was done research about pharmacognostic identification from muscle acid medicinal herbs that circulating at Makassar city., with aim to get pharmacognostic’s data from medicinal herbs of muscle acid that circulating at Makassar, for security in consuming. This research covers macroscopic and microscopic. On microscopic test medicinal herbs powder A, B dan C there are endosperm, parenkim with sekresi cell, fiber and calsium oksalat. From both offabove sample,really contains Zingiberis Rhizoma, Phaleria macrocarpa andyy `Piper nigrumKey word : Makroskopic, mikroskopic, muscle acid medicinal herbs
STUDI KOMPARASI AKTIVITAS ANTIOKSIDAN DAUN JERUK PURUT (Citrus hystrix DC) DAN DAUN JERUK NIPIS (Citrus aurantifolia (christm) Swingle) ASAL KOTA TERNATE MENGGUNAKAN METODE PEREDAMAN RADIKAL BEBAS DPPH Handayani, Virsa; Naid, Tadjuddin; Umasangaji, Ria Fitriani
Jurnal Ilmiah As-Syifaa Vol 12, No 1 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (102.36 KB) | DOI: 10.33096/jifa.v12i1.621

Abstract

Citrus (Citrus hystrix DC) and lime leaves (Citrus aurantifolia (christm) Swingle) are a Rutaceae family which contain flavonoids with antioxidant activity. The aim of this study is to compare the antioxidant activity of the citrus and lime leaves using DPPH free radical suppression method. The extraction of citrus and lime leaves by maceration method using ethanol 96 %. The antioxidant assay qualitatively by Thin Layer Chromatography (TLC) used the eluent n-hexane : ethyl acetat (7:3). The antioxidant assay quantitatively used DPPH free radical suppression method measured the absorption at the wavelength 515 nm. The results showed that the IC50 value of the citrus is 228.695 µg/mL. This showed that the potential of the antioxidant activity of the sample is weak; however, the IC50 value of the lime leaves is 335.064 µg/mL. this showed that the antioxidant activity of thev sample is not active.
STANDARISASI EKSTRAK AIR DAUN JATI BELANDA DAN TEH HIJAU Ahmad Najib; Abd. Malik; Aktsar Roskiana Ahmad; Virsa Handayani; Rezki Amriati Syarif; Risda Waris
Jurnal Fitofarmaka Indonesia Vol 4, No 2 (2017): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (891.618 KB) | DOI: 10.33096/jffi.v4i2.268

Abstract

Teh hijau memiliki nama spesies Camellia sinensis (L.) Kuntze, family Theaceae dan Jati belanda (Guazuma ulmifolia Lam.) termasuk kedalam family sterculiaceae Tujuan Penelitian ini adalah melakukan standarisasi ekstrak air daun jati belanda dan ekstrak air the hijau. Ekstrak distandardisasi dengan beberapa dua parameter yaitu parameter spesifik dan parameter non spesifik. Kadar sari larut air pada jati belanda 12,88 % dan teh hijau 40,88, sedangkan kadar sari larut etanol pada jati belanda 4, 23 % dan pada teh hijau 4,23 %. Hasil pengujian kandungan kimia menunjukkan pada ekstrak jati belanda mengandung saponin dan flavonoid sedangkan pada teh hijau mengandung tanin dan flavonoid. Kadar air ekstrak daun jati belanda 0,95 % dan teh hijau 2,79%. Hasil kadar abu total jati belanda sebesar 37,61% dan teh hijau 36,84%. Kadar abu tidak larut asam yaitu pada jati belanda sebesar 3,54% dan teh hijau 3,77%. Hasil dari penetapan susut pengeringan pada ekstrak jati belanda yaitu 0,46 % dan teh hijau 0,46 %. Ekstrak jati belanda maupun teh hijau berdasarkan pengujian standarisasi meliputi parameter spesifik dan non-spesifik memenuhi standarisasi mutu bahan baku.
Spectrophotometric Determination of Total Flavonoid Content in Biancaea Sappan (Caesalpinia sappan L.) Leaves Nurlinda Nurlinda; Virsa Handayani; Faradiba Abdul Rasyid
Jurnal Fitofarmaka Indonesia Vol 8, No 3 (2021): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v8i3.712

Abstract

AbstractBiancaea sappan  (BS) is traditionally used to treat anticonvulsants, anti-inflammatory, antiproliferative, anticoagulant, antiviral, immunostimulant, antioxidant, and antimicrobial treatments. Flavonoids are found in Secang; flavonoids are secondary metabolites that have antioxidant activity. This study aims to identify the flavonoids using TLC and determination of flavonoids content in BS leaves. Initially, The methanol extract of BS was obtained by maceration with ethanol. The qualitative analysis of flavonoid was using TLC and visualization by sprayed with AlCl3. The determination of total flavonoid content is conducted based on the AlCl3 method with total flavonoids expressed in QE (Quercetin equivalent) at the maximum wavelength of 431 nm. The research results showed that BS leaves contain flavonoids and the total flavonoid content of BS leaf extract is 1.0318 mg QE / g extract.Keywords: Caesalpinia sappan; Flavonoid content, Spectrophotometric
UJI TOKSISITAS EKSTRAK ETANOL TERPURIFIKASI BIJI MAHONI (Switenia mahagoni) Virsa Handayani; Ahmad Najib; Rezki Amriati Syarif; Abdullah Mahmud; La Hamidu; Aktsar Roskiana Ahmad
Jurnal Fitofarmaka Indonesia Vol 6, No 2 (2019): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (613.207 KB) | DOI: 10.33096/jffi.v6i2.511

Abstract

Mahoni is a medical plant which have the potential as drug. The aims of this research were to analysis phytochemical content and to test the toxicity of ethanol extract of seed from Mahoni. The Phytochemicals that analyzed were total phenolic, total flavonoid and condensed tannin. Toxicity test was assessed using BSLT method. Extraction was done by maseration method using ethanol as the solvent. In BSLT method, the shrimp larvae were placed in a series of test solution of varied concentration. The value of LC50 were obtained based on calculation of shrimp larvae lethality percentage using probit analysis. LC50 values of ethanol extract were 0,95 ppm.
KAJIAN FARMAKOGNOSTIK HERBA MENIRAN HIJAU (Phyllanthus niruri L.) dan HERBA MENIRAN MERAH (Phyllanthus urinaria L.) Virsa Handayani; Nurfadillah Nurfadillah
Jurnal Fitofarmaka Indonesia Vol 1, No 1 (2014): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (492.213 KB) | DOI: 10.33096/jffi.v1i1.196

Abstract

Herba meniran secara empiris telah lama digunakan oleh masyarakat sebagai obat tradisional. Ditinjau dari prospek yang sangat potensial sebagai bahan obat maka perlu dilakukan kajian farmakognostik sampel untuk pengendalian mutu dan keaslian simplisia. Penelitian ini bertujuan memberikan dasar ilmiah mengenai gambaran farmakognostik secara kualitatif dan kuantitatif. Hasil penelitian secara kualitatif dan kuantitatif telah dideskripsikan. Kajian morfologi  pada daun  herba meniran hijau (Phyllanthus niruri L.) dan daun  herba meniran merah (Phyllanthus urinaria L.) memiliki bentuk yang  sama. Pada batang memiliki perbedaan, meniran hijau percabangannya monopodial dan berwarna hijau sedang meniran merah percabangannya simpodial dan berwarna merah. Pada akar sama-sama berakar tunggang serta berwarna putih kekuningan. Berdasarkan kajian anatomi pada meniran hijau (Phyllanthus niruri L.) dan Meniran merah (Phyllanthus urinaria L.) memiliki bentuk yang sama baik dari daun, batang maupun akarnya. Berdasarkan kajian identifikasi kandungan kimianya pada meniran hijau (Phyllanthus niruri L.) mengandung tanin (katekol), saponin dan karbohidrat, sedangkan pada meniran merah (Phyllanthus urinaria L.) hanya mengandung tanin (katekol) dan saponin.
PENGUJIAN AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) TERHADAP BAKTERI PENYEBAB JERAWAT Virsa Handayani
Jurnal Fitofarmaka Indonesia Vol 2, No 1 (2015): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (606.628 KB) | DOI: 10.33096/jffi.v2i1.186

Abstract

Daun kersen (Muntingia calabura L) merupakan tanaman yang banyak tumbuh di Indonesia,tidak mengenal musim dan digunakan sebagai obat karena memiliki banyak khasiat salah satunya sebagai obat jerawat. Komponen senyawa kimia flavonoid, tannin dan saponin yang terdapat pada daun kersen diduga sebagai antibakteri. Tujuan penelitian ini untuk mengetahui apakah ekstrak etanol daun kersen mempunyai aktivitas antibakteri terhadap Staphylococcus epidermidis. Uji aktivitas antibakteri diakukan dengan metode difusi agar. Hasil penelitian menunjukkan bahwa ekstrak etanol daun kersen memiliki kemampuan menghambat pertumbuhan Staphylococcus epidermidis pada konsentrasi 1ppm, 3ppm, 5ppm, 9ppm, ekstrak etanol daun kersen efektif menghambat pertumbuhan Staphylococcus epidermidis.
ISOLASI DAN IDENTIFIKASI KOMPONEN KIMIA EKSTRAK N-HEKSAN DAUN PALA (Myristica fragrans) Virsa Handayani
As-Syifaa Jurnal Farmasi Vol 6, No 2 (2014): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (122.756 KB) | DOI: 10.33096/jifa.v6i2.43

Abstract

Nutmeg plant is a multi-purpose plant because each part can be utilized in the industry. Nutmeg  leaves contain essential oils and phenolic compounds. Essential oils are used as traditional medicine ingredients and as raw material for the manufacture of cosmetics, soaps, perfumes and others. This study aimed to isolate and identify the chemical components in the leaves of nutmeg (Myristica fragrans). Have done isolation and Identification of chemical components of the methanol extract of leaves pala (Myristica fragrans.) of 500 grams to determine the class of chemical components caontained in the leaf pala (Myristica fragrans.). The methanol extract which obtained by maseartion method 9,45 grams continued by solid liquid partition with n-hexane 4,61 grams extract. N-hexan extract isolated by column chromatography method obtained 37 bottles vials. Fraction D of the merger based on the appearance of spotting the chromatograms isolated by preparative thin-layer chromatography method, obtained 3 band. D.1 fractions isolated by TLC obtained a stain. In fractions spotting D.1 is obtained by testing a single two-dimentional TLC ang the elution system of multi eluen. Interpretation UV-Visible spectra data showed maximum  absorption at a wavelength 0f 273 nm and showed infrared fungtional group (OH) on the wave number (3927.78 cm-1, 3828.59 cm-1, 3743.30 cm-1, 3387.93 cm-1), group (CH) on the wave number (2925.93 cm-1, 2859.02 cm-1, 2364.17 cm-1), alken group (C = C) aromatik on the wave number (1642.54 cm-1, 1565.88 cm-1, 1516.65 cm-1, 1458.92 cm-1, 1114.33 cm-1), benzene group on the wave number ( 698.24 cm-1). Single spots obtained gave a positive reaction to spotting visualizer class of  flavonoids. Key words : Nutmeg , Isolation, Essential Oils.
STUDI ETNOFARMASI TANAMAN OBAT TRADISIONAL PADA MASYARAKAT DI KECAMATAN PENRANG, KABUPATEN WAJO, PROVINSI SULAWESI SELATAN Virsa Handayani; Andi Amaliah Dahlia; Andi Fenny Nurvadillah
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i1.841

Abstract

Indonesian community have been utillsing medicinal plants for years as an alternative treatment of a disease. Penrang is one of the areas located in Wajo Regency, South Sulawesi Province whre the majority is Buginese tribe. They use plants as a traditional medicine to cure various diseases. This research aimed to find out the types of plants used by local people in treating plants through shamans, community leaders and people who have knowledge about medicinal plants. The research method was purposive sampling. The research included 33 families and 54 species of ethnopharmacy still remains in the community to treat disesases that are used single-use or concoction, called jappi-jappi
Uji Aktivitas Antioksidan Ekstrak Metanol Bunga dan Daun Patikala (Etlingera elatior (Jack) R.M.Sm) Menggunakan Metode DPPH Handayani, Virsa; Ahmad, Aktsar Roskiana; Sudir, Miswati
Pharmaceutical Sciences and Research Vol. 1, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Patikala (Etlingera elatior (Jack) R.M.Sm) is a plant of the Zingiberaceae family. Patikala (E. elatior (Jack) R.M.Sm) have bioactive compounds are flavonoids that act as antioxidants. The purpose of this study was to measure free radical activity in the methanol extract of the fruit and leaves Patikala (E. elatior (Jack) R.M.Sm). Extraction of flowers and leaf samples by maceration method using methanol. Qualitative analysis of chemical compounds with certain eluent using Thin Layer Chromatography (TLC) to determine the group of active compounds in the extract. Antioxidant activity assay using the immersion method of DPPH (1,1-Diphenyl-2-picryl Hidrazil) measured absorption at a wavelength of 517 nm and compared with the power of antioxidant quersetin. The results showed that the methanol extract rendemen is at 1.935% for flowers and leaves at 5.17%. Antioxidant activity of the methanol extract of the flowers patikala (E. elatior (Jack) R.M.Sm) have low antioxidant activity with the value IC50 101.84 mg / mL and methanol extracts of leaves Patikala (E. elatior (Jack) R.MSm) have strong antioxidant activity with value IC50 30,65 mg / mL. This potential is lower than that of quercetin IC50 value of 5.35 mg / mL.
Co-Authors -, Auliawati A Amaliah Dahlia Abd. Malik Abd. Malik Abd. Malik ABD. MALIK Abdul Rasyid, Faradiba Abdullah Mahmud Ahamd, Aktsar Roskiana Ahmad Najib Ahmad, Akstar Roskiana Ahmad, Aktsar Roskiana Alfirah Angraeni AMINAH Andi Afifah Amdar Andi Amaliah Dahlia Andi Fenny Nurvadillah Andi Nur Alam Amaliah Anisa, Rianti Asfar, Akbar Asni Amin Asriani Suhaenah Dedy Putra Wahyudi Dwiyanti Puspitasari Fadliyah, Nurfadhilah Fauzan, Muh. Alif Noor Ganoko, Marwan Ahmad Gazali, Anggun Hamidu, La Hamsinah Harti Widiastuti Hasnaeni hasnaeni, Hasnaeni HM, Nur Rahmah Isti Aprilyanie Kamase, Jeni Miswati Sudir, Miswati Murfat, Moh Zulkifli Murfat, Zulkifli Nadya, Alifah Rifa Nur Rezky Khairun Nisaa Nurfadillah Nurfadillah Nurlinda Nurlinda Nurul Hasanah Nurul Ilmi Mufidah PRAHAYU, ADE CAHYA Putri, Andra Audina Rais Razak, Rais Reski Amriati Syarif Rezki Amriati Syarif Rezki Amriati Syarif Rezki Amriati Syarif Risda Waris Risda Waris Risda Waris, Risda Safriani Rahman Safriani Rahman, Safriani Selpida Handayani Selpida Handayani, Selpida Sudarman Suriyanti Tadjuddin Naid Tonang, Maswa Ruslan Umasangaji, Ria Fitriani Zainal Abidin