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Journal of Medicine and Health
ISSN : 24425227     EISSN : -     DOI : -
Core Subject : Health, Science,
Journal of Medicine and Health (JMH) is an open access journal (OAJ), a periodic scientific publication biannually online published on February and August; using review and screening system by peer group reviewer. JMH receives original research articles which related to medicine, health, new developing therapy from traditional medicine or herbs and developing clinical therapy. JMH also receives otiginal review articles, case report, continuing medicine and health study. Articles should be written in good English or Indonesian language.
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Articles 9 Documents
Search results for , issue "Vol 5 No 1 (2023)" : 9 Documents clear
A Case of Giant Dermoid Cyst at Sacrococcygeal in Adult at “X” Hospital in Bandung Farid Yudoyono; Christian Ade; Dilli MA Pratama; Hasan Baraqbah; Adhitya R Yudhadi
Journal of Medicine and Health Vol 5 No 1 (2023)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v5i1.2473

Abstract

Dermoid cysts are benign tumors that can be found anywhere in the body. There is no dermoid cysts clear data yet in Indonesia. In the spine, these tumors generally occur in the lumbar region and are often accompanied by congenital spinal dysrafism and/or dermal sinus passages. Dermoid cysts arise from abnormal growth of the ectodermal folds during pregnancy. Its incidence is 0.7 – 1.8% of all central nervous system tumors. The aim of reported this case is to highlight the role of a diagnostic and evaluate the surgical outcome. A 47 year old female patient with a lump in the sacrococcygeal area measuring 20 x 18 x 16 cm, with hard and soft consistency. MRI images show a hypo and hyperintense mass without spinal deformity. After the tumor was removed, the patient was allowed to go home for the 2nd day without complications. In conclusion, extraspinal dermoid cyst is a rare case that requires special diagnostic and surgical modalities to provide better clinical results.
Correlation between Family Support with Sexual Behavior and Antiretroviral Adherence on HIV/AIDS Patients in “A” Community Bandung Siska Febriyanti; July Ivone; Limdawati Kwee
Journal of Medicine and Health Vol 5 No 1 (2023)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v5i1.3398

Abstract

Family support is the attitude, action, and acceptance of the family towards its members. One of the functions of the family is to support the health care of other family members. HIV (Human Immunodeficiency Virus) is a retrovirus that attacks the immune system of CD4+ cells, and if not treated immediately, the patient will fall into an AIDS (Acquired Immunodeficiency Syndrome) condition. HIV/AIDS patients need support from both social and family. The incidence of HIV/AIDS in West Java during 2019 was ranked third in Indonesia, which was 6,066 patients. The aim of this study was to determine the relationship between family support with patient’s sexual behavior and adherence to taking antiretroviral drugs. The research method used is an analytical method with a cross-sectional design. The sample of this study was HIV patients who are members of Community "A" Bandung, with a total of 51 respondents. Statistical analysis showed that there was a correlation between family support and sexual behavior of HIV/AIDS patients (p=0.013), however, there was no correlation between family support and antiretroviral adherence (p= 0.12). In conclusion, family support is related to sexual behavior, but not related to adherence to taking antiretrovirals in HIV/AIDS patients.
microRNA: Sebuah panduan pemula untuk klinisi dan peneliti Ardo Sanjaya
Journal of Medicine and Health Vol 5 No 1 (2023)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v5i1.3540

Abstract

MicroRNA (MiRNA) adalah RNA pendek (sekitar 22 nukleotida) yang tidak mengkode pembentukan protein tetapi mengatur banyak fungsi penting dalam tubuh manusia. MiRNA pertama ditemukan pada tahun 1993 dan sekarang telah ditemukan mempengaruhi hampir semua penyakit manusia. MiRNA menjalani jalur pemrosesan terpisah dengan beberapa langkah di dalam nukleus dan sitoplasma. Proses ini juga dikontrol dengan ketat di banyak titik, menciptakan jalur regulasi yang sangat kompleks. Gangguan jalur ini dapat menyebabkan fenotipe penyakit seperti yang ditunjukkan oleh banyak pola ekspresi MiRNA yang terkait dengan keadaan penyakit. Namun, perkembangan mikroRNA masih relatif baru, dan ada banyak hal yang masih belum kita ketahui. Oleh karena itu, artikel reviu ini bertujuan untuk memberikan pendahuluan mengenai MiRNA mulai dari sejarahnya hingga perkembangan terbaru bagi para klinisi dan peneliti. Dalam pembuatan reviu ini dilakukan pencarian dengan kata kunci MiRNA melalui sistem pencarian PubMed pada pangkalan data MEDLINE. Hasil pencarian yang relevan akan dipilih oleh peneliti untuk diikutsertakan dalam artikel ini. Berdasarkan pencarian didapatkan bahwa MiRNA memiliki regulasi yang sangat kompleks dengan efek yang luas pada tubuh manusia. Efek dari MiRNA ini dapat ditemukan pada kondisi infark myokard, diabetes, hingga kanker. Suatu hari nanti, terapi berbasis RNA mungkin menjadi hal yang umum sehingga peneliti dan klinisi harus terbiasa dengan subjek yang berkembang pesat ini.
Vitiligo: Update of Pathogenesis and Treatment Erico L Yonathan
Journal of Medicine and Health Vol 5 No 1 (2023)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v5i1.3954

Abstract

Vitiligo merupakan kelainan pigmentasi kronis dengan prevalensi sekitar 1% populasi dunia. Vitiligo ditandai dengan lesi makula depigmentasi, tidak berskuama, berwarna putih seperti kapur, dan biasanya asimtomatik. Hipotesis terjadinya vitiligo pertama kali dilaporkan sekitar tahun 1950 berupa hipotesis genetik. Artikel ini bertujuan membahas mengenai patogenesis, diagnosis dan tatalaksana vitiligo terbaru. Artikel reviu ini ditulis berdasarkan sumber pustaka berupa buku teks kedokteran dan jurnal-jurnal yang dipublikasikan dalam 10 tahun terakhir. Penelitian terbaru mengenai patogenesis vitiligo banyak diteliti, di antaranya adalah genetik, stres oksidatif, proses autoimun, gangguan adhesi melanosit, neurohumoral, autositotoksisitas, defisiensi vitamin D, hiperhomosisteinemia, dan teori konvergensi. Diagnosis vitiligo ditegakkan berdasarkan pemeriksaan fisik, serta pemeriksaan penunjang sesuai indikasi. Terapi vitiligo konvensional meliputi terapi farmakologi, fototerapi, dan pembedahan. Terapi vitiligo konvensional tidak berfokus pada patogenesis terjadinya vitiligo. Simpulan, Terapi vitiligo terbaru memiliki tiga prinsip, yaitu mengurangi stres pada melanosit, mengatur autoimunitas, dan stimulasi regenerasi melanosit sedang dilakukan. Terapi vitiligo terbaru diharapkan dapat meningkatkan efektivitas terapi. Penelitian efektifitas terapi terbaru pada vitiligo perlu dilakukan lebih lanjut.
Karakteristik Klinis dan Tatalaksana Pasien Glaukoma Sudut Terbuka Primer di Pusat Mata Nasional, Rumah Sakit Mata Cicendo, Bandung, Indonesia Azmi I Salsabila; Andika P Gandasubrata; Maula Rifada
Journal of Medicine and Health Vol 5 No 1 (2023)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v5i1.4265

Abstract

Glaucoma is the largest cause of permanent blindness globally. Primary open-angle glaucoma (POAG) is one of chronic glaucoma and is asymptomatic in the early stage. This study was performed to identify the clinical characteristics and management of POAG patients at the Cicendo Eye Hospital, Bandung, Indonesia. This retrospective, descriptive study was conducted on medical records of POAG patients in Cicendo Eye Hospital in January-December 2020 using whole sampling method. Sociodemographic, clinical characteristics, and management data were collected. From 147 subjects obtained, the largest age group of POAG patients was 60-69 years old (30.6%), with most of the patients being male (68.0%). Most of the patients experienced blindness (37.6%) and had cup-to-disc ratio (CDR) 0.9-1.0 (36.8%). The mean of pre-treatment IOP was 29.1±13.1 mmHg, and the mean of post-treatment was 19.3±7.7 mmHg. The mean of anti-glaucoma medication in the first and the last control were 1.93±0.59 and 1.48±0.70, respectively. The most common treatments were medication only (69.8%), with combined surgery as the most performed surgery. In conclusion, most POAG patients were 60 years old or older and male, with most eyes being blind. The POAG treatments were mostly anti-glaucoma medication only to lower IOP as the goals of the treatment.
THE INHIBITION EFFECT OF MORINGA (Moringa oleifera L.) LEAVES AND RED GINGER RHIZOME (Zingiber officinale Rosc.) PT. "P" ETHANOL EXTRACT ON ENHANCEMENT SERUM CREATININE LEVELS OF MALE WISTAR RATS DYSLIPIDEMIA MODEL Juliana Wijaya; Penny S Martioso; Sugiarto Puradisastra
Journal of Medicine and Health Vol 5 No 1 (2023)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v5i1.4528

Abstract

Elevation of serum creatinine levels is a biomarker of decreased kidney function. Dyslipidemia can decrease kidney function. Long-term consuming statins can increase creatinine levels. Moringa leaves (Moringa oleifera L.) and red ginger rhizomes (Zingiber officinale Rosc.) have antioxidant effects. Aim of study is to determine the inhibitory effect on increasing serum creatinine levels of concoction Moringa Leaves and Red Ginger Rhizome ethanol extract (CML-RGRE). True laboratory experimental study with completely randomized design was conducted on 30 male Wistar rat dyslipidemia models, induced by high-fat feeding (HFF)-Propylthiouracil (PTU) 0.01% for 21 days. Subjects were divided into six groups (n=5), Group I, II, III were treated CML-RGRE 135, 202.5, 270 mg/kg BW, IV dyslipidemia control, V Rosuvastatin 1.8 mg/kg BW, and VI fenofibrate 5.4 mg/kg BW, all still given HFF-PTU for 21 days. Serum creatinine levels (mg/dL) were measured 3 times, after acclimatization, created dyslipidemia models, and treatment using spectrophotometer, colorimetric kinetic methods. Data were analysed with paired t-test, ANOVA test, and Fischer's LSD, α = 0.05. All doses of CML-RGRE have effectively inhibited the increase serum creatinine levels (p < 0.01). Conclusion, Moringa Leaves and Red Ginger Rhizome ethanol extract effectively inhibited the increased serum creatinine levels of animal dyslipidemia models.
Uji Validitas Eosinopenia Pada Pasien Sepsis Berdasarkan Kriteria Konsensus Sepsis-3 Adrian Suhendra; Ida Parwati; Adhi K Sugianli
Journal of Medicine and Health Vol 5 No 1 (2023)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v5i1.5351

Abstract

Sepsis remains a major global healthcare problem, indicate as most frequently cause of morbidity and mortality worldwide. The last consensus of sepsis in 2016 defined sepsis as life threatening organ dysfunction caused by a dysregulated host response to infection. Dysfunction of organs can be represented by Sequential [Sepsis-Related] Organ Failure Assessment (SOFA) score. Score2 points or more consequent to the infection. Nowadays, there is ideal biomarkers of sepsis such as procalcitonin (PCT). However, the use of that markers in developing countries are hardly accessible. Eosinopenia is an prepossess biomarker because eosinophil count is always measured in daily practice and considered as a forgotten marker. The study purpose is to determine the validity of absolute eosinopenia in bacterial sepsis patients. This study is a descriptive observational study, collecting 118 patient’s medical record data from the past, diagnosed as sepsis using consensus criteria of Sepsis-3 between January 1st 2018–December 31st 2019. Eosinopenia validity test in sepsis patients showed 92.7% specificity and 71.4% sensitivity. This study also showed significant differences of absolute eosinophil count between positive sepsis patients and negative group with p value <0.001. Eosinopenia had high specificity so it could be used as a marker of diagnostic in septic patients.
Hubungan antara Durasi Penggunaan Gawai Selama Masa Pandemi COVID-19 dengan Computer Vision Syndrome pada Mahasiswa FK Unika Atma Jaya Jakarta Julia R Tanjung; Cornelia T Tantra; Nelson Sudiyono
Journal of Medicine and Health Vol 5 No 1 (2023)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v5i1.5688

Abstract

Pandemi COVID-19 berimbas pada peningkatan durasi penggunaan gawai untuk kegiatan pendidikan daring yang berdampak buruk bagi kesehatan mata, salah satunya, Computer Vision Syndrome (CVS). Penelitian ini bertujuan untuk mengetahui hubungan durasi penggunaan gawai dengan CVS pada mahasiswa kedokteran Fakultas Kedokteran dan Ilmu Kesehatan Universitas Katolik Indonesia Atma Jaya. Metode penelitian potong lintang dengan 98 responden (76 perempuan, 22 laki-laki) berusia 17-21 tahun, menggunakan Modified computer vision syndrome questionnaire dan aplikasi pengukur durasi penggunaan gawai. Rerata durasi penggunaan gawai adalah 610 menit per hari. Sebanyak 70% responden menggunakan gawai dengan rerata durasi >8,9 jam per hari. Prevalensi CVS ditemukan sebesar 47,9%, dimana 25,5% responden mengalami CVS derajat ringan dan 22,4% responden mengalami CVS derajat sedang hingga berat. Analisis Bivariat dengan uji Chi-square memperlihatkan hubungan yang bermakna antara durasi penggunaan gawai dengan derajat keparahan CVS (p<0,05). Simpulan penelitian ini, terdapat hubungan antara durasi penggunaan gawai dengan derajat keparahan Computer Vision Syndrome pada mahasiswa Fakultas Kedokteran Unika Atma Jaya Jakarta selama masa pandemi Covid-19.
Kontribusi Kepatuhan Konsumsi Obat Antihipertensi dan Terkendalinya Tekanan Darah Pasien Hipertensi di Puskesmas Cisauk, Kabupaten Tangerang, Banten Shirley I Moningkey; Iegreat Aprilyanri; I Gusti AN Hirania; Lidia Arita; Wahyuni L Atmodjo
Journal of Medicine and Health Vol 5 No 1 (2023)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v5i1.6097

Abstract

Hipertensi merupakan masalah kesehatan dengan tingkat prevalensi tertinggi di dunia. WHO mencatat bahwa terdapat 1 dalam 5 orang dengan hipertensi yang terkontrol disebabkan kepatuhan penderita hipertensi dalam mengonsumsi obat yang masih kurang. Walaupun beberapa penelitian melaporkan mengenai pengaruh kepatuhan mengonsumsi obat antihipertensi dengan terkendalinya tekanan darah tinggi, namun masih terdapat perbedaan pada kebermaknaan pada hasil penelitiannya. Tujuan penelitian ini adalah untuk membuktikan kontribusi kepatuhan konsumsi obat antihipertensi dengan terkendalinya tekanan darah pada penderita hipertensi. Penelitian ini menggunakan metode studi potong lintang terhadap 78 penderita tekanan darah tinggi di Puskesmas Cisauk yang memenuhi kriteria penelitian. Data kepatuhan meminum obat antihipertensi diamati dengan kuesioner Morrisky Medication Adherence Scale 8 (MMAS-8). Hasil penelitian menunjukkan 47 (60,3%) subyek hipertensi tidak patuh terhadap pengobatan hipertensi, sedangkan 56 (71,8%) subyek memiliki tekanan darah yang tidak terkendali yaitu >140/90. Hubungan antara kedua variabel pada penderita hipertensi di Puskesmas Cisauk yang dianalisa dengan metode chi-square menunjukkan kebermaknaan dengan p<0,0001 dan OR=5,35. Penelitian ini menyimpulkan apabila pasien tidak patuh minum obat antihipertensi maka kemungkinan akan mengalami hipertensi 5,35 kali lebih besar.

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