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International Journal of Cardiovascular Practice
ISSN : 24767174     EISSN : 2476468X     DOI : -
Core Subject : Health,
International Journal of Cardiovascular Practice(IJCP) is an international quarterly journal dedicated to a broad spectrum of topics in cardiology. All manuscripts must be prepared in English, and are subject to a rigorous and fair peer-review process. Accepted papers will immediately appear online followed by printed hard copy.
Arjuna Subject : -
Articles 198 Documents
The Correlation between Serum Level of N-Terminal Pro-B-type Natriuretic Peptide and Gensini Score in Patients with Acute Coronary Syndrome Mohammad Hassan Namazi; Hossein Vakili; Mahsa Charkhkar; Latif Gachkar; Isa Khaheshi
International Journal of Cardiovascular Practice Vol. 1 No. 2 (2016)
Publisher : Publisher: Shahid Beheshti University of Medical Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20286/ijcp-010205

Abstract

Introduction: N-terminal pro-B-type natriuretic peptide (NT-proBNP) has emerged as an important biomarker for developing the diagnosis and prognosis of cardiovascular diseases, as several studies have shown that serum levels of NT-proBNP elevate in acute coronary syndrome (ACS) and coronary artery disease (CAD). We performed this study to find any possible correlation between serum levels of NT-proBNP and Gensini score in patients diagnosed with ACS.Methods: In a cross-sectional study, 100 consecutive patients with ACS who were candidates of angiography were recruited and their serum levels of NT-proBNP, Gensini scores, lipid profiles and troponin I levels were measured.Results: Sixty six male and 34 female patients with a mean age of 57.5 years, including 44 with unstable angina, 33 with ST-elevation myocardial infarction, and 23 with non-ST-elevation myocardial infarction were enrolled. The mean serum NT-proBNP level and the Gensini score were 1987.16 pg/mL (17.9-8841) and 31.09 (6-92.5), respectively. The serum NT-proBNP levels and Gensini scores were significantly correlated with a Spearman correlation coefficient of 0.953 (P < 0.001). Serum levels of NT-proBNP were not different in patients with single-vessel disease, 2-vessel disease and 3-vessel disease (P = 0.257). NT-Pro-BNP levels were also correlated positively with troponin I levels (correlation coefficient = 0.779) and negatively with left ventricular ejection fraction (correlation coefficient = -0.55). Smoker patients had higher NT-proBNP levels (P = 0.047). Neither Gensini scores nor NT-Pro-BNP levels had significant correlation with lipid profile or blood sugar.Conclusions: NT-proBNP is directly correlated with Gensini score in patients with ACS and might be used as an important marker for risk stratification in those patients.
Effect of Nocturnal Oxygen Therapy on Electrocardiographic Changes Among Patients with Congestive Heart Failure Mehdi Pishgahi; Rama Bozorgmehr; Masoud Rastgari; Mohammad Amin Abbasi
International Journal of Cardiovascular Practice Vol. 1 No. 2 (2016)
Publisher : Publisher: Shahid Beheshti University of Medical Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20286/ijcp-010204

Abstract

Introduction: Nocturnal hypoxia is an important factor in increasing the risk of mortality in patients with chronic heart failure and is associated with atrial and ventricular arrhythmias. In addition, QT dispersion (QTd) is used as a prognostic sign in determining future malignant arrhythmias and sudden cardiac death. In the current study, we investigated the effect of nocturnal oxygen therapy (NOT) on electrocardiographic changes among patients with chronic heart failure.Methods: In this study, a consecutive of 154 patients (87 males and 67 females) known with chronic heart failure (EF ≤ 40%) were enrolled. The patients were administered NOT (oxygen flow of 2 L/min for 8 hours during sleeping). Electrocardiography was takenbefore and after the NOT, and RR interval, PR interval and QTd were measured each time.Results: The mean age of the participants was 61.3 ± 11.4 years. Our results revealed significant reduction in QTd (55.8 ± 7.5 vs. 61.4± 9.1 msec, P = 0.001) and heart rate (79.6 ± 4.7 vs. 76.8 ± 4.3, P = 0.001) in a patient’s electrocardiogram after NOT.Conclusions: In this study, NOT decreased heart rate and QTd in patients with chronic heart failure, but not PR interval, which could consequently decrease the risk of malignant arrhythmias and sudden cardiac death.
Acute Compartment Syndrome of the right lower extremity following Autologous Blood transfusion: A Case report Feridun Sabzi; Aghigh Heidari; Fataneh Ghasemi; Abbas Ahmadi
International Journal of Cardiovascular Practice Vol. 1 No. 3 (2016)
Publisher : Publisher: Shahid Beheshti University of Medical Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21859/ijcp-010302

Abstract

Compartment syndrome (CS) is an extremely rare complication during cardiac surgery and rare case reports have been linked to coronary artery bypass surgery.We report one case of right lower extremity compartment syndrome (CS) following inadvertent blood transfusion through a catheter which was inserted into a vein in the related extremity. Forceful pushing of blood through a delicate vein led to rupture of the vein wall and subsequent extravasation of blood into the perivascular tissue as into an intra-compartment portion of the lower extremity.Late detection of this complication led to compartment syndrome. The patient underwent emergency fasciotomy and concomitant removal of intra compartment and subcutaneous blood and fluids. After fasciotomy, the normal color of skin and pulse were recovered.
One- and Six-month Outcomes of Patients with Non-ST Elevation Myocardial Infarction Hossein Vakili; Roxana Sadeghi; Neda Toofaninejad; Tooba Akbari; Naser Kachoueian
International Journal of Cardiovascular Practice Vol. 1 No. 3 (2016)
Publisher : Publisher: Shahid Beheshti University of Medical Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21859/ijcp-010303

Abstract

Introduction: Use of risk scoring systems in patients with acute coronary syndrome helps with summarizing important prognostic data of the disease and facilitates calculating confidence limits and comparing survival rates between different treatments. In the present study, the researchers first aimed at assessing mid-term outcome of patients with non-ST elevation myocardial infarction (NSTEMI), and then determining main predictors of this outcome to improve definitive criteria for designing a risk scoring system in the population.Methods: In a prospective cohort study, 124 patients with NSTEMI, diagnosed according to ACC/AHA guidelines and hospitalized in an academic hospital in 2013, were consecutively assessed. Baseline characteristics were collected via interviewing, physical examination, and reviewing the recorded files. All the patients were followed for one and six months to assess mid-term outcomes regarding mortality and major adverse cardiac events (MACE). MACE is defined as the occurrence of at least one of the events of death, myocardial infarction, repeated revascularization, or re-hospitalization.Results: One-month death occurred in 3.2%, re-hospitalization in 4.0%, and myocardial infarction in none of the patients. In addition, regarding the six-month outcomes status, mortality rate was determined in 6.4%, re-hospitalization in 22.6%, and myocardial infarction in 4.8% of patients. Hence, one- and six-month MACE rates were 7.3% and 27.4%, respectively. Furthermore, three- and six-month survival rates were estimated to be 96.8% and 93.6%, respectively. According to the Cox-proportion hazard modeling, only reduced left ventricular ejection fraction (LVEF) (HR = 0.909, P = 0.017), history of chronic kidney injury (HR = 8.884, P = 0.005), and Inotrope use (HR = 35.759, P = 0.012) could predict the six-month MACE. None of the other indexes including general coronary risk factors, echocardiography parameters, and level of cardiac enzymes could predict mortality rate.Conclusions: Patients with NSTEMI may face high six-month MACE which can be predicted by low LVEF, history of renal injury and use of inotrope. Therefore, to define risk stratification system, these indicators should be considered as well.
Cardiac failure secondary to hypocalcemia Mohammad Hasan Namazi; Isa Khaheshi; Mahsa Charkhkar; Shooka Esmaeeli; Habib Haybar
International Journal of Cardiovascular Practice Vol. 1 No. 3 (2016)
Publisher : Publisher: Shahid Beheshti University of Medical Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21859/ijcp-010304

Abstract

Hypocalcemic cardiomyopathy due to hypoparathyroidism is a very atypical and rare circumstance, which is usually intractable to conventional therapy for cardiac failure, but responds satisfactorily to restoration of normocalcemia.We describe a young woman who developed clinical signs of hypocalcemia due to hypoparathyroidism, reduced left ventricular ejection fraction and polymorphic ventricular tachycardia as consequences of hypocalcemia.This case underscores the importance of biochemical abnormalities like hypocalcemia as a rare cause of secondary cardiomyopathy and emphasizes on the need for effective and immediate treatment of hypocalcemia and its related causes.
Updates on Advanced Therapies for Acute Pulmonary Embolism Bavand Bikdeli; Behnood Bikdeli
International Journal of Cardiovascular Practice Vol. 1 No. 3 (2016)
Publisher : Publisher: Shahid Beheshti University of Medical Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21859/ijcp-010301

Abstract

Venous thromboembolism is the third common vascular disease after acute myocardial infarction and stroke, and acute pulmonary embolism (PE) remains as the most common preventable cause of in-hospital mortality. In addition to routine anticoagulant therapy, several advanced treatment options have been introduced over the past three decades. We provide a succinct and contemporary summary of the evidence base and important indications for inferior vena caval filter placement, systemic and catheter-based thrombolytic therapy, as well as percutaneous and surgical thrombectomy. Appropriate case selection for advance therapies for PE could minimize the adverse effects and costs, while optimizing the outcomes.
Aerobic Exercise and Eucalyptus Globulus: Cardio-affective effects on recovery and stress Alfredo Anderson Teixeira-Araujo; Jackson R.G.S. Almeida; Loumaíra Carvalho da Cruz; Xirley P Nunes; Sérgio Rodrigues Moreira
International Journal of Cardiovascular Practice Vol. 2 No. 1 (2017)
Publisher : Publisher: Shahid Beheshti University of Medical Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21859/ijcp-020101

Abstract

Introduction: It is necessary to investigate the interrelation between physical exercise and aromatherapy, regarding cardiovascular and affective functions of human. Thus, the aim of this study was to evaluate the effects of aerobic exercise (AE) and eucalyptus essential oil (EO) in cardiovascular and affective responses.Methods: Twelve adults (19-39 years) performed in a randomized order in different days: 1. AE session; 2. Inhalation of EO session; 3. AE + EO session and; 4. Control session. In each session remained at rest over 15min plus 5min to inhaling EO or blank air in Control session. The AE was 15 min run/walk at 80-85% of maximum heart rate. After recovery (30 min) the Cold Pressor Test (CPT) was applied. At rest, recovery and during CPT were measured cardiovascular and affective variables.Results: The variation of systolic blood pressure in the CPT was attenuated by AE +EO (12.3 ± 14.9 mmHg) and EO (12.6 ± 6.7 mmHg) compared to Control (17.3 ± 6.5 mmHg; P < 0.05). AE + EO increased pleasure in recovery (1′ = 1.2 ± 1.9 pts and 30′= 0.6 ± 1.1 pts) and reduced displeasure in stress (-3.4 ± 1.7 pts) when compared to Control in recovery (1′= -0.5 ± 1.4 pts and 30′= -0.7 ± 1.5 pts, respectively; P < 0.05) and stress (-4.6 ± 1.8 pts; P < 0.05).Conclusions: We conclude that aerobic exercise and eucalyptus essential oil attenuated cardiovascular responses and modulated the affect on recovery and stress.
ST–Segment elevation: Not always an acute coronary syndrome Érico Costa; Elsa Meireles; Catarina Rodrigues; Tiago Godinho Teixeira; Dulce Silva
International Journal of Cardiovascular Practice Vol. 2 No. 1 (2017)
Publisher : Publisher: Shahid Beheshti University of Medical Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21859/ijcp-020102

Abstract

Cardiac tumors can be primary or metastatic, the latter being more frequent and usually of pulmonary or hematologic origin. These patients’ clinical signs are non-specific and the electrocardiogram (ECG) can assume many patterns, among which, ST-segment elevation. Nevertheless, associated occlusion of the coronary arteries is rare in these situations.We present a 79-year-old woman with a history of pulmonary neoplasia who was admitted to the emergency department due to atypical chest pain, cough and worsening dyspnea in the previous 3 days. The ECG revealed an ST-segment elevation in the anterolateral and inferolateral leads, despite normal blood work, namely normal troponin. Due to the disparity between the patient’s symptoms and the ECG findings, a decision was made not to proceed to primary angioplasty, but to further investigate with echocardiography, which revealed a mass localized in the anterolateral and inferolateral left ventricle walls, confirmed by computed tomography. The patient was admitted in the medical ward for symptomatic management. Her clinical condition gradually deteriorated due to the disease’s natural evolution and she died two weeks later.This case highlights the importance to keep in mind differential diagnoses to acute coronary syndromes, when a ST-segment elevation is encountered on an ECG.
The Effect of Hyperuricemia on the Rate of Contrast-Induced Nephropathy in Patients with Coronary Angiography Hossein Vakili; Sara Chaghazardi; Isa Khaheshi; Mohammadreza Naderian
International Journal of Cardiovascular Practice Vol. 1 No. 3 (2016)
Publisher : Publisher: Shahid Beheshti University of Medical Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21859/ijcp-010305

Abstract

Introduction: There is little information about the relationship between hyperuricemia and contrast induced nephropathy. The present study aimed to evaluate the relationship between hyperuricemia and contrast induced nephropathy among patients, who had undergone coronary angiography.Methods: In the current study, 200 consecutive patients with coronary artery disease, who underwent coronary angiography in Modarres hospital, were enrolled. According to the available data, the upper limit normal level of uric acid was defined as 7 mg/dl in males and 6.5 mg/dl in females. By increasing level of serum creatinine to 0.5 mg/dl (or 25% enhancement) from basic level of creatinine during 48 hours of introduction of contrast agent, diagnosis of Contrast Induced Nephropathy (CIN) was established. The relationship between hyperuricemia and CIN was then assessed.Results: There is a significant difference between normouricemic patients and hyperuricemic patients, in aspect of weight (P = 0.011) and uric acid (P = 0.001); however, other quantitative and qualitative variables including age, volume of contract agent, creatinine level after angiography, hemoglobin level, gender, arterial access type, number of involved vessels, were insignificant between the two groups (P > 0.05). Moreover, as an essential finding, CIN was shown in 9% of normouricemic patients and 10% of hyperuricemic  patients with no significant difference between the two groups (P = 0.6).Conclusions: Our study suggests that hyperuricemia may not significantly increase the rate of the contrast-induced nephropathy in patients, who had undergone angiography
Chronic Total Occlusion-Angioplasty with Antegrade Approach: A two-Year Experience in “Modarres Hospital”, A Tertiary University Hospital, Tehran, Iran Morteza Safi; Mohammad Hasan Namazi; Hamid Sadeghi; Habibollah Saadat; Hossein Vakili; Saeed Alipour Parsa; Isa Khaheshi; Bahar Ataeinia
International Journal of Cardiovascular Practice Vol. 1 No. 3 (2016)
Publisher : Publisher: Shahid Beheshti University of Medical Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21859/ijcp-010307

Abstract

Introduction: New techniques for the percutaneous treatment of coronary chronic total occlusions (CTO) have had a high success rate since a few years ago, so the interest for this treatment has been increasing these days.Methods: The current observational study was performed in Modarres hospital as a tertiary referral center. All the patients with documented stable angina who had failed to response to full guideline-mediated medical therapy, referred to our hospital, were candidates for coronary angiography. Antegrade strategy was applied for all these patients. The length of the lesion, the fluoroscopy time of the CTO angioplasty, consumed contrast volume, the number of guide wires used, whether a corsair or tornus micro-catheter was used or not, and the success rate of the angioplasty were documented for further analysis.Results: A total of 47 patients with documented stable angina were finally included. The median age was 59 (45-78) and 70.2% were male. The mean length of the lesion was 34.0 ± 1.1 .The mean fluoroscopy time and contrast volume were 57.9 ± 3.2 minutes and 525.9 ± 20.9 mL, respectively. In average, 2.2 guide wires were used. Corsair and tornus micro-catheters were applied in 30 (63.8%) and 5 (10.6%) of the cases, respectively. Seven complications (all including coronary dissection) occurred. In-hospital major adverse cardiac events (MACE) rate was 10.6%, all of which were non-Q wave myocardial infarction. The success rate was 85.1%. The higher number of used wires, use of corsair, and tornus micro-catheter were not significantly concordant with success rate (P-value > 0.05); in addition, longer lesion was not concordant with unsuccessfulness rate (P-value > 0.05).Conclusions: Patient selection for CTO-angioplasty should be performed more carefully. Patients’ quality of life and risk of probable procedural complications and future cardiac events should be assessed to decide the best treatment approach. Radiation exposure, contrast consumption and fluoroscopy time are recommended to be monitored during the procedure and thresholds should be defined to enhance safety and efficacy.