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JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)

jmpf
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Published by Universitas Gadjah Mada

ISSN : 20888139 EISSN : 24432946 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology Public Health

JMPF is the first open access journal in Indonesia specialized in both research of pharmaceutical management and pharmacy practice. Articles submitted in JMPF are peer reviewed, we accept review articles and original research articles with no submission/publication fees. JMPF receives manuscripts in both English (preferably) and Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. JMPF is also open for various fields such as pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, goverment policies related to pharmacy, and pharmaceutical care.

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Articles 8 Documents

Search results for , issue "Vol 9, No 4" : 8 Documents clear

Profil Kerapuhan dan Masalah terkait Obat pada Kelompok Lanjut Usia di Panti Jompo Kota Surabaya Verlita Evelyn Susanto; Adji Prayitno Setiadi; Bobby Presley; Steven Victoria Halim; Eko Setiawan
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 9, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Frailty and drug related problems (DRPs) are common among elderly who lives in the nursing home. There is currently limited information available regarding the profile of frailty and DRPs among elderly living in the nursing homes in Indonesia. This project aims to describe the profile of frailty and DRPs among nursing home residents in Surabaya. This cross-sectional study was conducted in three nursing homes in Surabaya. Integrated Systematic Care for older People (ISCOPE) questionnaire was used to identify the frailty profile among participants. Beers Criteria, screening tool of older person’s prescriptions (STOPP), geriatric dosage handbook and drug interactions analysis and management were used as tools to identify and analyse drug related problems in this study. Several DRPs were identified in this study including inappropriate drug choices, drugs interaction, and inappropriate dose of drugs. In total, 68 elderly were recruited in this study and 41.18% of them were classified as frail older people. There was no drugs interaction with “clinical significance” being identified, however, inappropriate dose of drugs and potentially inappropriate drug choices were found in 58.82% and 19.12% of nursing home residents, respectively. Findings regarding the profile of frailty and DRPs among elderly may indicate the needs to implement an appropriate intervention strategic in order to optimize the use of medications among nursing homes-dwelling elderly people.

Potential Incompatibility Problem of Intravenous Drugs’ Administration among Intensive Care Unit (ICU) Patients at PKU Muhammadiyah Yogyakarta Hospital Ardhanarishwari Umi Salamah; Fita Rahmawati; Fivy Kurniawati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 9, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.40930

Drugs’ administration among hospitalized patients in ICU commonly is given intravenously. Mixing the intravenous drugs may result in incompatibility problem that might affect the drugs’ stability and bioavailability. The aim of the study was to investigate the potential incompatibility problem of intravenous mixing drugs’ administration among ICU patients at PKU Muhammadiyah Yogyakarta Hospital. This study was a cross-sectional study in which design and data was obtained from ICU patients’ medical record retrospectively with purposive sampling in order to observe the pattern of intravenous drug’s combination. The potential incompatibility problem was analyzed using Handbook on Injectable Drugs. There were 79 out of 119 medical records which fulfilled sample inclusion criteria taken in this study. Parenteral dosage form was commonly used rather than non parenteral (62.06%) among ICUs’ patients. The potential incompatibility pattern consisted of incompatibility of intravenous drugs, electrolyte solutions/parenteral nutritions in mixture form, and the electrolyte solutions/parenteral nutritions, which are administrated simultaneously. Potential incompatibility of intravenous dosage was found in 50 events out of 79 patients (0.63 events per patients), which consisted of 8 events (8.51%) in using of drugs administrated simultaneously, 10 events (19.23%) in using of electrolyte solutions/parenteral nutritions in mixture form, and 32 events (11.72%) in using of electrolyte solutions/parenteral nutritions administrated simultaneously. Common potential incompatibilities types were precipitation of drugs and drug’s adsorption to packaging materials.

Analisis Perencanaan dan Ketersediaan Obat di Kabupaten dan Kota Provinsi Jawa Timur Digdo Suryagama; Satibi Satibi; Sumarni Sumarni
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 9, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

The problem of drug availability always occurs in District/Municipality every year. Research related to drug management, especially those related to the evaluation of drug availability and the value of damaged/expired drugs, has been carried out in the last ten years. Almost all the research found problems with the availability of the drugs. The Director General of Pharmacy and Medical Devices reported that the percentage of the availability of National Medicines in East Java in 2017 had reached 96.55%, but had not yet described the condition of the availability of medicines in real terms because the calculation did not use data on drug quantity. This study aims to explain the real conditions for the availability of 17 items of national indicator drugs in East Java in 2017, as well as identify problems and information about management that has been running in 2017. This research is an observational research that is descriptive quantitative. The research instrument was in the form of data collection sheets for the availability of 17 drug items in 2017 and interview guidelines. The results showed that the availability of drugs was in excess conditions with an average of 22.5 months. Drug programs held directly by the Central Government often experience excess inventory at the Regency/City Pharmacy Department level but the average percentage of drugs damaged/expired is still in a fairly good range (0-3%). It can be concluded that the availability of drugs in East Java Province in 2017 is influenced by the planning system, procurement system, availability of drugs at the provider level (supply), availability of management information systems and respective regional policies.

Development of Cost Analysis Guidance for Indonesian Hospitals Ragil Setia Dianingati; Arthorn Riewpaiboon
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 9, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Health technology assessment is important in the process of national health insurance system development. On the other hand, health technology assessment study needs a cost analysis as a basic, which is a troublesome if there is not any guidance. To help performing the cost analysis study, this study describes the development of a costing manual book and template as a guide for costing analysis in Indonesian hospitals. This management tool developed in stages, from tool drafting, testing in the real life environment, to approval from stakeholders. Costing templates were developed using Microsoft Excel formulas, such as IF, SUMIF and TRANSPOSE. The costing manual book and template were designed for the Indonesian hospital context. The costing template successfully assessed the unit costs of healthcare services in the study hospital. It can calculate the unit costs of healthcare services for 3 main objectives: hospital internal management, reimbursement rate setting and economic evaluation. The costing analysis tool was reviewed and approved by the study hospital staff and stakeholders. Even the model test was only tested in one district hospital, but it was designed to be flexible enough to adapt to different hospital organization structures. The cost analysis guidance is relevant and applicable to district hospitals in Indonesia. It is well accepted by stakeholders and helpful in calculating the hospital unit costs in a practical way. Hopefully, there will be further hospital cost analyses in the future. These cost analyses can then be used as inputs for universal health coverage development.

Analisis Kualitas Hidup Pasien Diabetes Melitus Tipe 2 Berdasarkan Pola Peresepan Antidiabetik dan Komplikasi Pande Made Desy Ratnasari; Tri Murti Andayani; Dwi Endarti
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 9, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that requires lifelong therapy to control blood glucose. The long term use and different mechanism of action antidiabetic have the potential cause side effects and discomfort that affects the quality of life. This study aimed to determine differences in the quality of life of patients with T2DM based on antidiabetic prescribed and complications at the Outpatient of Panembahan Senopati Bantul Yogyakarta Hospital in September 2017. This research is observational with a cross-sectional design. Quality of life data is taking concurrently using the Diabetes Quality of Life Clinical Trial Questionnaire and patient's medical record. This study involved 200 T2DM patients who received antidiabetic at least 3 months before study, aged ≥18 years and agreed to inform concent. Sociodemographic data, antidiabetic prescribed and complications were described descriptively. Differences in the quality of life based on antidiabetic prescribed and complications using the Kruskal Wallis test which was further analyzed using the post hoc by Mann Whitney test. The results showed the majority of patients received oral combination with insulin (48.5%) and dominated by macrovascular complications (19.5%). The average value of patient's quality of life is 65.7. There was difference quality of life based on antidiabetic prescribed in the domain of treatment satisfaction (p=0.000) between oral monotherapy with combination of oral and insulin (p=0.000) and insulin monotherapy with combination of oral and insulin (p=0.002). There were differences in quality of life based on complications in the mental health domain (p=0.003) between macrovascular and microvascular (p=0.011) and between microvascular and without complications (p=0.001).

Insidensi dan Faktor Risiko Infeksi Luka Operasi pada Bedah Obstetri dan Ginekologi di Rumah Sakit Farahdina Chairani; Ika Puspitasari; Rizka Humardewayanti Asdie
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 9, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Surgical Site Infection (SSI) is a type of Healthcare-associated infections (HAIs) which caused postoperative morbidity. SSI is widely reported in developing countries with a combined incidence of 11.8 episodes per 100 surgical procedures. This study aimed to identify risk factors for SSI in patients undergoing obstetric and gynecological surgeries at Dr. Sardjito General Hospital Yogyakarta. Data collection was conducted retrospectively using patient’s medical records during the period of January 1, 2017 to December 31, 2018. A total of 102 patients underwent obstetric and gynecological surgeries in the study period. The incidence of SSI in the cross sectional study was 9.80%. Obstetric surgeries had a lower SSI incidence compared to gynecological surgeries (1.96% versus 7.84% respectively). The risk factors for SSI identified in the bivariate analysis were comorbidity (P= 0.03), concomitant surgery (OR 8.25), intraoperative blood loss (OR 0.51), perioperative blood transfusion (OR 18.6), and duration of prophylactic antibiotics (OR 1.22). The results of multivariate analysis showed a significant relationship between intraoperative blood loss and SSI (OR 0.038, CI 95% 0.002-0.761; P= 0.032). Incidence and risk factors from our retrospective study on obstetric and gynecological surgeries can be reported simultaneously. Some of the risk factors identified in this study can be helpful for SSI risk stratification in hospital.

Luaran Penggunaan Analgesik Opiat pada Pasien Kanker Salma Fajar Puspita; Zullies Ikawati, Apt.; Retno Muliawati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 9, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Cancer pain might reduce the quality of life of cancer patients. Opioids are the drug of choice in cancer pain management. Fentanyl and other opioids are often prescribed. This study was aimed to compare the pain intensity reduction and quality of life of patients with cancer pain using transdermal fentanyl and other opioids. This prospective cohort study Oinvolved cancer outpatients with pain at the Tulip International Cancer Center of RSUP Dr. Sardjito, Yogyakarta fulfilling inclusion and exclusion criteria. Follow-up was carried out 2 weeks after recruitment. Pain intensity and quality of life were obtained through interview process using Numerical Rating Scale (NRS) and EORTC QLQ-C30 questionnaire. Patient demographic and disease status were obtained from medical records. Clinical outcomes (reduction in pain intensity and achievement of pain targets) and quality of life in the transdermal fentanyl and oral opioid groups were presented descriptively because of the low research power. Total respondents involved were 111 patients, 13 (11.71%) patients used transdermal fentanyl and 98 (88.29%) patients used oral opiates. The effect of opioid on reduction of pain intensity, achievement of pain targets and quality of life cannot be justified even though descriptively transdermal fentanyl shows better outcomes than oral opioid. The reduction of pain intensity was influenced by age (p = 0,000) and global health status was influenced by the stage of the cancer (p = 0.045).

Hubungan Penyakit Diabetes Melitus dan Penggunaan Antidiabetes terhadap Rekurensi pada Pasien Kanker Payudara Fitri Wulandari; Kartika Widayati; Fita Rahmawati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 9, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Breast cancer is the cancer with the most prevalence of 43.3% and the mortality rate that reaches 12.9%. The prognosis of breast cancer can be affected by diabetes mellitus (DM), so that efforts to control DM through antidiabetic therapy are very necessary, but antidiabetic therapy is also reported to be associated with the prognosis of breast cancer. The purpose of this study was to determine the relationship of diabetes and antidiabetic use to recurrence in breast cancer patients. This study used a retrospective cohort design, involving 176 female non-metastatic breast cancer patients who received chemotherapy, consisting of 88 patients with DM and 88 non-DM patients. The exposures in the study were diabetes mellitus and the types of antidiabetic drugs (metformin and non metformin based therapy), while the study output was the recurrence of breast cancer. The research data was obtained from the patient’s medical records at RSUP Dr. Sardjito Yogyakarta. Research analysis used Chi-square, Kaplan Meier method and Cox-regression to estimate Hazard Ratio with 95% confidence interval. The results showed DM in breast cancer patients was associated with increased the risk of recurrence (HR 2,458; 95% CI 1,571-3,846, log rank test P=0,000), while the use of antidiabetic types (metformin and nonmetformin) to control DM in breast cancer patients was not associated with the risk of recurrence (HR 1.391; 95% CI 0.816 - 2.370, log rank test P=0.210). Further research is warranted by monitoring blood glucose levels regularly.

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