cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota adm. jakarta timur,
Dki jakarta
INDONESIA
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian
Published by Universitas Muhammadiyah Prof. Dr. Hamka
ISSN : 20866968     EISSN : 26219816     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Farmasains: Jurnal Ilmiah Ilmu Kefarmasian is an national journal published by Faculty of Pharmacy and Science University of Muhammadiyah Prof. DR. HAMKA. Farmasains: Jurnal Ilmiah Ilmu Kefarmasian is aimed at being a medium for research results dissemination and scientific paper exchanges on the pharmaceutical field among academics, practitioners, regulators, and public. Farmasains: Jurnal Ilmiah Ilmu Kefarmasian is issued two times annually, i.e., in April, and October.The Editor receives rigorous research manuscripts that have not been offered for publication elsewhere. Since its first issue published in 2010. Farmasains: Jurnal Ilmiah Ilmu Kefarmasian has become a CrossRef Member since 2019. Therefore, all articles published by Farmasains: Jurnal Ilmiah Ilmu Kefarmasian will have unique DOI number with p-ISSN 2086-6968 dan e-ISSN 2621-9816
Arjuna Subject : -
Articles 5 Documents
 1 
Search results for , issue "Vol. 13 No. 1 (2026)" : 5 Documents clear
Proteksi Ekstrak Daun Pacing Terhadap Resistensi Insulin dan Studi Keamanannya terhadap Fungsi Hati dan Ginjal Nurfazri Istiqomah, Aulia; Lestari, Kharina Septi; Aligita, Widhya; Rahmah, Farizkah; Novianti, Tamia Rizqi; Raveani, Vina Julia
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 13 No. 1 (2026)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v13i1.17593

Abstract

Insulin resistance is one of the primary causes of diabetes mellitus, leading to reduced tissue sensitivity to insulin and an increased risk of metabolic complications. The Ethanol Extract of Pacing leaves (EEPL) was evaluated for its potential to prevent insulin resistance in a rat model of diabetes induced by a high-fat, high-fructose diet. The rats were administered EEPL at doses of 150, 300, and 450 mg/kg Body Weight (BW) for 42 days. In addition, a 90-day subchronic toxicity study was conducted to assess potential adverse effects on the liver and kidneys. The results demonstrated that a dose of 300 mg/kg BW significantly improved insulin sensitivity. Biochemical parameters, including creatinine, urea, Serum Glutamic Oxaloacetic Transaminase (SGOT), and Serum Glutamic Pyruvic Transaminase (SGPT), remained within normal ranges, indicating preserved liver and kidney function. However, mild histopathological changes were observed in the kidneys, such as glomerular congestion and tubular necrosis, while the hepatic structure remained normal, with no significant hepatocellular damage. In conclusion, EEPL at a dose of 300 mg/kg BW provides an effective protective effect against insulin resistance, with relatively good safety for long-term use. Nevertheless, further studies are required to confirm its safety in humans.
Bibliometric Analysis of Two Decades of Global Research on the Ethnopharmacological Value of Pimpinella pruatjan Kashuri, Mohamad
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 13 No. 1 (2026)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v13i1.19400

Abstract

Research on Pimpinella pruatjan (Apiaceae, locally known as purwoceng), an Indonesian medicinal plant valued for its aphrodisiac properties and cultural significance, remains limited in terms of global visibility and scientific recognition. To address this gap, a bibliometric assessment spanning two decades (2005–2025) was conducted using the Scopus database and a PRISMA-based screening approach, with VOSviewer applied to map publication trends, collaboration networks, institutional productivity, and thematic density using Callon centrality profiling. Findings reveal a fragmented yet progressively growing research landscape, dominated by non-endemic countries such as Iran and Japan, whereas contributions from Indonesia remain limited. Existing studies predominantly focus on reproductive pharmacology and phytochemical characterisation, while toxicological validation, clinical testing, and ecological sustainability remain largely underexplored. Thematic mapping also exposes weak research collaboration, methodological inconsistency, and limited engagement with indigenous knowledge holders. Advancing P. pruatjan as a credible phytomedicine necessitates standardised cultivation practices, comprehensive toxicological and clinical investigations, and inclusive international collaborations that strengthen local institutional capacity. Strengthening interdisciplinary collaboration and institutional commitment will enhance Indonesia’s role in global ethnopharmacology and promote sustainable innovation in evidence-based herbal medicine.
Eco-friendly Powder Sunscreen Combining Kaolin and Zinc Oxide with Determination of Sun Protection Factor Aspadiah, Vica; Sahumena, Muhammad Handoyo; Suryani, Suryani; Muliadi, Rahmat; Sinta, Dwi
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 13 No. 1 (2026)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v13i1.19626

Abstract

Excessive exposure to UV radiation can cause skin damage, making sunscreen use necessary. However, chemical ingredients may have negative impacts on marine ecosystems. Therefore, an eco-friendly powder sunscreen combining kaolin and zinc oxide was developed. This study aimed to determine the formulation, evaluate the physical characteristics, and assess the effectiveness of UV protection by determining the SPF value. The study used a mixing method followed by physical characteristic testing, including organoleptic evaluation, pH measurement, homogeneity, adhesion, moisture content, fineness degree, and SPF determination using a UV-Vis spectrophotometer. The results showed that the combination of kaolin and zinc oxide produced a formula with good physical characteristics, including a light brown colour, a distinctive odour, a smooth and homogeneous texture, a pH ranging from 6.78 to 7.29, adhesion ranging from 82% to 90%, moisture content ranging from 0.05% to 0.25%, a powder fineness of 95%, and SPF values ranging from 13.69 to 16.01. The best formulation was Formula 5, containing 25% kaolin and 25% zinc oxide, which met the required characteristics and showed the highest SPF value of 16.01. This combination of ingredients can be utilised to produce an effective and environmentally friendly loose powder sunscreen.
Uji Aktivitas Tabir Surya Ekstrak Etanol Kulit Markisa Ungu secara In Vitro dengan Spektrofotometri Uv-Vis Agtri, Nisa Aulia; Ariastuti, Reni; Qonitah, Fadilah
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 13 No. 1 (2026)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v13i1.20601

Abstract

Excessive exposure to Ultraviolet (UV) radiation can cause skin damage, including erythema, premature ageing, and skin cancer. Sunscreen is commonly used to protect the skin from UV radiation. The peel of purple passion fruit (Passiflora edulis) contains phenolic and flavonoid compounds that may provide UV-absorbing activity. This study aimed to evaluate the sunscreen activity of the ethanol extract of purple passion fruit peel in vitro based on the Sun Protection Factor (SPF), Erythema Transmission Percentage (%Te), and Pigmentation Transmission Percentage (%Tp). The extract was obtained by maceration with 96% ethanol. Qualitative identification of phenolic compounds was performed using a FeCl3 reagent, while flavonoids were detected using concentrated HCl and magnesium powder. Sunscreen activity was evaluated using UV-Vis spectrophotometry at concentrations of 400, 600, 800, 1,000, and 1,200 ppm. The results showed that the extract contained phenolic and flavonoid compounds. At the highest concentration (1,200 ppm), the SPF value was 20.086±1.696 (ultra-protection), %Te was 0.697±0.149, and %Tp was 4.413±0.594, all of which were categorised as sunscreen. One-way ANOVA analysis indicated significant differences among concentration variations (p<0.05). In conclusion, the ethanol extract of purple passion fruit peel has potential as a natural active ingredient for sunscreen.
Pengaruh Minyak Sacha Inchi (Plukenetia volubilis L.) terhadap Kadar MDA Plasma Tikus Wistar Diinduksi Klorpirifos Rahayu, Putri; Tajudin, Tatang; Pertiwi, Yuniariana
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 13 No. 1 (2026)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v13i1.20756

Abstract

The use of chlorpyrifos remains prevalent in Indonesia, and excessive exposure can trigger oxidative stress, as indicated by increased Malondialdehyde (MDA) levels. Sacha inchi oil (Plukenetia volubilis L.) contains antioxidant compounds that may mitigate oxidative stress. This study investigated the effect of sacha inchi oil on plasma MDA concentrations, Body Weight (BW), and clinical parameters in male Wistar rats exposed to chlorpyrifos. Thirty rats were allocated to five groups (n=6 per group): a normal control, a negative control (chlorpyrifos 10 mg/kg BW/day), and three treatment groups receiving sacha inchi oil orally at doses of 1, 2, and 4 mL/kg BW/day for 28 days. Plasma MDA levels were measured using the TBARS method with spectrophotometric detection at 532 nm, and data were analysed by One-Way ANOVA followed by Tukey’s HSD test. Chlorpyrifos exposure increased MDA levels (18.83 nmol/mL) compared with the normal control, whereas sacha inchi oil reduced MDA levels in a dose-dependent manner to 11.32, 8.98, and 3.90 nmol/mL (p<0.05). Supplementation promoted BW gain and ameliorated clinical manifestations, including lethargy, alopecia, and increased respiratory rate, with no mortality observed in treated groups. Sacha inchi oil exhibited protective effects against chlorpyrifos-induced oxidative stress, demonstrating maximal efficacy at 4 mL/kg BW/day.

Page 1 of 1 | Total Record : 5

 1 

Filter by Year

2026 2026


Reset
Filter By Issues
All Issue Vol. 13 No. 1 (2026) Vol. 12 No. 2 (2025) Vol. 12 No. 1 (2025) Vol. 11 No. 2 (2024) Vol. 11 No. 1 (2024) Vol. 10 No. 2 (2023) Vol. 10 No. 1 (2023) Vol. 9 No. 2 (2022) Vol. 9 No. 1 (2022) Vol. 8 No. 2 (2021) Vol. 8 No. 1 (2021) Vol. 7 No. 2 (2020) Vol. 7 No. 1 (2020) Vol. 6 No. 2 (2019) Vol 6 No 1 (2019) Vol. 6 No. 1 (2019) Vol 5 No 2 (2018) Vol. 5 No. 2 (2018) Vol. 5 No. 1 (2018) Vol 5 No 1 (2018) Vol 4 No 2 (2017) Vol. 4 No. 2 (2017) Vol. 4 No. 1 (2017) Vol 4 No 1 (2017) Vol. 3 No. 2 (2016) Vol 3 No 2 (2016) Vol 3 No 1 (2016) Vol. 3 No. 1 (2016) More Issue