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Contact Name
Ajuk Sapar
Contact Email
ajuk.sapar@chemistry.untan.ac.id
Phone
+6281282990575
Journal Mail Official
anthoni.b.aritonang@chemistry.untan.ac.id
Editorial Address
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Tanjungpura University Jl. Prof. Dr. Hadari Nawawi, Pontianak, Kalimantan Barat, Indonesia
Location
Kota pontianak,
Kalimantan barat
INDONESIA
Indonesian Journal of Pure and Applied Chemistry
ISSN : 26208571     EISSN : 2620858X     DOI : -
Core Subject : Science,
Indonesian Journal of Pure and Applied Chemistry (IJoPAC) was first established in 2018 as a scientific journal that accommodates researchers and education practitioners to publish scientific work and research results which are the results of experiments or literature studies in the field of chemistry. Publications are carried out periodically with three issues (January-April, May-August, September-December) in one volume per year. Published scientific work can be in the form of original articles, short communications and review results covering the fields of Physical chemistry, Organic chemistry, Analytical chemistry, Inorganic chemistry, Biochemistry / Biological Chemistry, Applied Chemistry. Focus and Scope of Indonesian Journal of Pure and Applied Chemistry covering the fields : Physical chemistry Organic chemistry Analytical chemistry Inorganic chemistry Biochemistry/Biological Chemistry Applied Chemistry
Articles 7 Documents
Search results for , issue "Vol 6, No 3 (2023)" : 7 Documents clear
KARAKTERISASI DAN STUDI SINERGI ANALOG KURKUMIN DARI SENYAWA 4-METOKSIBENZALDEHIDA SEBAGAI ANTIDIABETES DENGAN METODE IODIN (CHARACTERIZATION AND SYNERGY STUDY OF CURCUMIN ANALOGS FROM 4-METHOXYBENZALDEHYDE COMPOUND AS AN ANTIDIABETIC USING IODINE METHOD) Khoirotun Nafillah; Chairil Anwar
Indonesian Journal of Pure and Applied Chemistry Vol 6, No 3 (2023)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v6i3.67301

Abstract

Curcumin is the main component of turmeric with various biological activities, one of which is antidiabetic. However, curcumin has low bioavailability and fast metabolism, so repeated doses are required if used as a medicine. Curcumin analogs have better bioavailability than curcumin. This study aims to synthesize curcumin analog from 4-methoxybenzaldehyde and monoketone (cyclohexanone and cyclopentanone), and their synergism effect using iodine method. The compounds A and B have been synthesized using Claisen-Schmidt condensation from benzaldehyde derivatives using KOH 8% and ethanol as solvent. The results showed that the curcumin analogs A and B were yellow solids with yields of 31,13% and 31,87%, respectively. The structure of products was characterized by FTIR, DI-MS, 1H- and 13C-NMR, showed that curcumin analogs A is 2,6-bis(4-methoxybenzylidene)cyclohexanone and curcumin analogs B is 2,6-bis(4-methoxybenzylidene)cyclopentanone. α-amylase inhibition assay of curcumin analogs A and B were performed by formation of amylum-iodine complex with UV-vis spectrophotometer at wavelength of 600 nm, showed that 33,03% and 91,5% at concentration 1 mM. Synergy studies with ferulic acid indicated that compound A 99,23% at a concentration ratio (1:8) and B 99,14% (1:4). This indicates a synergy between curcumin analogs and ferulic acid as an inhibitor of the α-amylase.
DAYA HAMBAT EKSTRAK DAUN MANGROVE (Rhizophora apiculata) ASAL PESISIR SUKADANA TERHADAP BAKTERI Escherichia coli (INHIBITION THE LEAF EXTRACT OF Rhizophora apiculata FROM THE SUKADANA COAST AGAINST Escherichia coli) Muhamad Agus Wibowo; Ninda Kumala Sari; Puji Ardiningsih; Afghani Jayuska
Indonesian Journal of Pure and Applied Chemistry Vol 6, No 3 (2023)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v6i3.69965

Abstract

Rhizophora apiculata is a plant that is widely found in mangrove forests in Sukadana subdistrict, and has the potential to inhibit of Escherichia coli. This research aims to determine the activity of R. apiculata which grows in the Sukadana mangrove forest in inhibiting E. coli. The leaves of R. apiculata were macerated with methanol solvent, partitioned into three fractions (n-hexane fraction, dichloromethane fraction, and methanol fraction), and tested for phytochemical screening. The results of phytochemical screening of R. apiculata leaves were positive for flavonoids, alkaloids, phenolics, terpenoids, tannins, and saponins. The potential of R. apiculata leaf samples in inhibiting bacterial growth was measured by the size of the clear zone in the antibacterial test with the agar well diffusion method that uses variations in concentration, namely 250 mg/mL, 125 mg/mL, and 62.5 mg/mL. Based on the research results, it is known that R. apiculata leaves can inhibit the growth of the test bacteria with a minimum inhibitory concentration for methanol extract of 250 mg/mL. The methanol and dichloromethane fractions had minimum inhibitory concentrations of 125 mg/mL and 250 mg/mL respectively, while the n-hexane fraction did not inhibit at all test concentrations. So it can be concluded that the leaves of R. apiculata have the potential as an alternative for antibacterial active compounds
SYNTHESIS OF MAGNETITE-MODIFIED NATURAL ZEOLITE USING COPRECIPITATION AND PHYSICAL MIXING TECHNIQUES Teguh Pambudi; Hilman Imadul Umam
Indonesian Journal of Pure and Applied Chemistry Vol 6, No 3 (2023)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v6i3.66363

Abstract

The synthesis of magnetite-modified natural zeolite has been carried out using two techniques, namely coprecipitation and physical mixing. The characteristics (crystallinity, pore characteristics, and recovery capabilities) of the resulting composites are compared. In addition, the effect of the Fe3O4 fraction (25.0% w/w, 33.3% w/w, and 50.0% w/w) on the composite characteristics was also evaluated. The results showed that the natural zeolite/Fe3O4 prepared using the coprecipitation technique showed better distribution of Fe3O4 than the physical mixing technique. It was observed that the natural zeolite's XRD peak intensity decreased as the Fe3O4 content increased. In accordance with the N2 adsorption-desorption isotherm, the pore spaces of the natural zeolite have been found to be filled by suspended Fe3O4 particles. Therefore, both natural zeolite/Fe3O4 prepared by coprecipitation and physical mixing had smaller pore diameters than washed natural zeolite. Then, in terms of recovery ability, natural zeolite/Fe3O4 prepared using the coprecipitation technique has greater recovery ability than natural zeolite/Fe3O4 prepared by physical mixing, with an increase in the Fe3O4 percentage typically enhancing the composite's recovery ability.
PENETAPAN KADAR FLAVONOID, FENOLIK DAN AKTIVITAS ANTIOKSIDAN EKSTRAK BUAH Tabernaemontana Macrocarpa JACK ASAL KALIMANTAN BARAT (DETERMINATION OF FLAVONOID, PHENOLIC, AND ANTIOXIDANT ACTIVITY OF Tabernaemontana Macrocarpa JACK FRUIT EXTRACT FROM WEST KALIMANTAN) Andi Hairil Alimuddin; Rudiyansyah Rudiyansyah; Masriani Masriani
Indonesian Journal of Pure and Applied Chemistry Vol 6, No 3 (2023)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v6i3.63749

Abstract

Tabernaemontana macrocarpa Jack is one of the plants from the Tabernaemontana genus in the Apocynaceae family. Some compounds from the genus Tabernaemontana have shown interesting biological activities. Unfortunately, information about secondary metabolites and the bioactivity of T. macrocarpa Jack is limited. This study was conducted to determine the total phenolics and flavonoids contents of seeds flesh and fruit of T. montana together with their antioxidant activity. The seeds flesh and fruit of T. macrocarpa were extracted by maceration using methanol. Phytochemical tests showed that methanol extracts of seeds flesh and fruit contain alkaloids, flavonoids, and polyphenols. Total phenols and flavonoids were determined quantitatively by spectrometry and it showed that the seeds flesh contained more polyphenolics and flavonoids than the fruit. The results of the antioxidant activity showed that the seeds flesh and fruit extracts did not have antioxidant activity since their IC50 values were > 500 mg/L.
METABOLIT SEKUNDER DARI FRAKSI AKTIF AKAR PANDAN (Pandanus amaryllifolius roxb.) YANG BERSIFAT ANTIFEEDANT TERHADAP Epilachna sparsa (SECONDARY METABOLITES OF THE ACTIVE FRACTION OF PANDAN ROOT (Pandanus amaryllifolius roxb.) AS ANTIFEEDANT AGAINST Epilachna sparsa) Ari Widiyantoro; Harlia Harlia; Annisa Dyah Astari Putri
Indonesian Journal of Pure and Applied Chemistry Vol 6, No 3 (2023)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v6i3.71213

Abstract

Pandan wangi (Pandanus amaryllifolius Roxb.) contains flavonoids, terpenoids, steroids, saponins, alkaloids and tannins which can be used as antifeedant compounds. This study aims to determine the antifeedant activity and to identify of secondary metabolites from pandan roots extract against Epilachna sparsa. The antifeedant activity test was carried out on the methanol extract and the partition yeild fraction. The research was carried out by maceration of pandan root which had been mashed into powder with methanol solution to obtain a methanol extract of 86.51 g. The extract was then separated by partitioning to obtain methanol fraction, ethyl acetate fraction, dichloromethane fraction and n-hexane fraction. The methanol extract and fraction from partition results were then tested for antifeedant activity against Epilachna sparsa. The results showed that at a concentration of 6% the methanol extract had an antifeedant activity of 59.37 ± 2.11 % against Epilachna sparsa. The fractions resulting from the partition included methanol, ethyl acetate, dichloromethane and n-hexane fractions at a concentration of 6% respectively showing antifeedant activity of 81.25 ± 3.56 %; 75.00 ± 2.99 %; 37.50 ± 3.77 % and 21.18 ±1.23 %. Based on the antifeedant activity test results, the methanol fraction showed the best activity. Furthermore, the methanol fraction was separated and purified by chromatographic techniques. The isolate obtained was 53.11 mg in the form of white needle crystals and had a melting point of 135-138oC. The isolate based on the phytochemical test showed positive for flavonoid
VARIATION OF SINTERING TEMPERATURE IN THE SYNTHESIS OF FLUORAPATITE FROM SNAIL SHELLS (Achatina fulica) USING THE SOL-GEL METHOD Charlena Charlena; Yessie Widya Sari; Wulan Islamia
Indonesian Journal of Pure and Applied Chemistry Vol 6, No 3 (2023)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v6i3.67697

Abstract

Dental caries can cause porous cavities and even broken teeth, necessitating natural teeth extraction and replacement with implants. Fluorapatite, a dental implant material, can be synthesized from snail shells containing 98% calcium carbonate. This study aims to identify the characteristics of fluorapatite and determine the effect of variations in sintering temperature on the synthesis of fluorapatite made from snail shells using the sol-gel method. Variations of sintering temperature used are 700, 900, and 1100 °C. The results showed that fluorapatite synthesized with the sintering temperature of 900 °C demonstrates the highest crystallinity, according to the diffractogram results, there is an 83% presence of the apatite phase at an angle of 31.8126°, with a crystal size of 79 nm and a particle size of 0.5 µm. Fourier-transform infrared spectroscopy analysis on the sample showed the presence of OH, OH−F, and PO43− functional groups. The sample showed a spongy surface morphology with hexagonal-shaped flowers—a Ca/P molarity ratio 1.67
EFFECT OF POTASSIUM HYDROXIDE CONCENTRATION AS A CATALYST ON THE YIELD OF COCONUT OIL (Cocos nucifera) TRANSESTERIFICATION Chaleb Paul Maanari; Sanusi Gugule; Feti Fatimah; Aisyiah Restutiningsih Putri Utami; Mustapa Mustapa; Stefan Marco Rumengan; Miftahul Jannah; Jakub Saddam Akbar; Djois Sugiaty Rintjap
Indonesian Journal of Pure and Applied Chemistry Vol 6, No 3 (2023)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v6i3.65513

Abstract

Research has been carried out on the effect of potassium hydroxide catalyst concentration on the yield of coconut oil (Cocos nucifera) transesterification and continued to characterize the reaction results. The concentration of potassium hydroxide used was 1, 2, and 3% by weight of coconut oil with ethanol as the reactant. The data processing used was the one-way analysis of variation and its characterization from a physicochemical perspective, followed by the analysis of gas chromatography-mass spectroscopy (GCSM) and infrared spectrophotometry. Based on the data processing results, potassium hydroxide concentrations of 1, 2, and 3% did not affect the yield of the transesterification reaction of coconut oil, and the results were 74.5264%, 71.9330%, and 69.0420%. The characterization results show that the physicochemical properties of the reaction products, such as acid number, density, and viscosity, comply with the Indonesian National Standard (SNI) for biodiesel. The results of the GCMS analysis showed that nine peaks were dominated by ethyl laurate.

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