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Contact Name
Raymond Pranata
Contact Email
raymond_pranata@hotmail.com
Phone
+6282112918892
Journal Mail Official
ijc@inaheart.org
Editorial Address
Editorial Office: Heart House, Jalan Katalia Raya No. 5, Kota Bambu Utara West Jakarta, 11430 - Indonesia Telephone: +62 21 5681149, Fax: +62 21 5684220 Email: ijc@inaheart.org
Location
Kota adm. jakarta barat,
Dki jakarta
INDONESIA
Indonesian Journal of Cardiology
ISSN : 28303105     EISSN : 29647304     DOI : -
Core Subject : Health,
Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other health professionals for scientific articles in the cardiovascular field. All articles (research, case report, review article, and others) should be original and has never been published in any magazine/journal. Prior to publication, every manuscript will be subjected to double-blind review by peer-reviewers. We consider articles on all aspects of the cardiovascular system including clinical, translational, epidemiological, and basic studies. Subjects suitable for publication include but are not limited to the following fields: Acute Cardiovascular Care Arrhythmia / Cardiac Electrophysiology Cardiovascular Imaging Cardiovascular Pharmacotherapy Cardiovascular Public Health Policy Cardiovascular Rehabilitation Cardiovascular Research General Cardiology Heart Failure Hypertension Interventional Cardiology Pediatric Cardiology Preventive Cardiology Vascular Medicine
Articles 12 Documents
Search results for , issue "Vol. 28, No. 6 November 2007" : 12 Documents clear
Penilaian Disinkroni Kardiak Dengan Pemeriksaan Ekokardiografi Amiliana M Soesanto
Jurnal Kardiologi Indonesia Vol. 28, No. 6 November 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i6.204

Abstract

Penilaian disinkroni kardiak merupakan salah satu aspek penting dari pemeriksaan ekokardiografi dalam menilai fungsi jantung. Disinkroni (disinkroni mekanik) adalah suatu gerakan yang tidak sinkron atau tidak seragam dari otot jantung. Bila ditinjau dari periode dalam siklus jantung, disinkroni bisa terjadi pada saat sistolik maupundiastolik. Walaupun demikian, sampai saat ini baru disinkroni sistolik yang banyak diteliti dan diketahui implikasi klinisnya pada beberapa kelainan jantung.
Dynamic Interaction Between Organellas In the Management of Cytosolic Calcium Huvecs Exposed to 22 mM Glucose With Different Period Exposure Olly Indrayani PWM; Djanggan Sargowo; Mochammad Aris Widodo; Rully MA Roesli; S Sumarno
Jurnal Kardiologi Indonesia Vol. 28, No. 6 November 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i6.205

Abstract

Background.In our previous research, when cell culture were exposed to high glucose, this will cause the increase of H2O2. At the exposure to 22 mM glucose on 3rd day, the increase of H2O2 that induced the activation of Phospholipase C (PLC) have caused 1P3 (Inositol tri-phosphate) mobilizing the release of Ca²+ from the depo Endoplasmic reticulum (ER). Thus, causing the increase of cytosolic Ca²+. Giving thapsigargin (TG) will cause significant increase in Cytosolic Ca²+ so that the most contribution to the increasing of Cytosolic Ca²+ derives from the ER . On the 7th day exposure, H2O2 played the same role as TG, causing direct incease in Cytosolic Ca²+ and an addition of Ca²+ free/buffer ethyleneglyco bis (ßaminoethyl ether).&NNN’N’– tetraacetic acid (EGTA) caused significant decrease of cytosolic Ca²+ basal and the greatest contribution to the increase of cytosolic Ca²+ on the 7th day, comes from extracellular. Administrating Cyclosporin A (CSA) 10 µM on the 9th day, caused significant decreasing on cytosolic Ca²+ basal, the ability of CSA in decreasing Ca²+ basal concentration was less than the 3rd and 7th days. At a high glucose condition with different length of exposure, a change of new cytosolic Ca²+ homeostatic regulation occurred and this enable a change in the dynamic interaction among ER, extracellular and mitochondria.Method.HUVECs culture exposed to 22 mM glucose for 3, 7 and 9 days. The cells were incubated with FURA2-AM. The evaluation of fluorescence cytosolic Ca²+ was done by epifluorescence Nikon digital camera-computerized analyser. To measure the cytosolic Ca²+ concentration we use Histogram Image Corel Draw Photo Paint 12.Result. Exposure to glucose 22mM on the 3rd day (65.4 ± 12.2) it showed the increase of cytosolic Ca²+ by giving Ca²+ free/EGTA 1 mM and CSA 10 mM caused the decrease of cytosolic Ca²+ (33.2 ± 4.47) TG1µM and CSA caused the decrease of cytosolic Ca²+ basal (53.07 ± 2.75) and Ca²+ -free/EGTA, TG and CSA (68.59 ± 5.71). On the 7th day exposure (92.74 ± 7.66) the decrease of cyto -solic Ca²+ basal occurred at the giving of Ca²+ -free/EGTA, TG (50.52 ± 9.23). EGTA and CSA (45.59 ±6.2). TG and CSA (73.55 ± 7.30), Ca²+ -free/EGTA and TG much more decrease the concentrate of cytosolic Ca²+ basal (17.58 ±4.5). On the 9th day of exposure to glucose (72.32 ±7.46), the giving of Ca²+ -free/EGTA, TG and CSA(35.76 ± 5.25) have caused the decrease of cytosolic Ca²+ basal. Conclusion.HUVECs culture exposed to 22mM glucose will cause the increase in H2O2and cytosolic Ca²+ basal. ER, mitochondria and extracellular regulate the Cytosolic Ca²+ and a dynamic interaction occurred among them to obtain a new homeostatic.
Hipertrofi Ventrikel Kiri Disertai Dengan Pembesaran Diameter Osteum Vena Pulmonal Radityo Prakoso; Erika Maharani; Mohammad Syaifur Rohman; Budiyanto Nagawidjaja; Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 28, No. 6 November 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i6.206

Abstract

Background:Hypertensive heart disease, characterized with left ventricular hypertrophy (LVH), which is usually accompanied with left ventricular dysfunction, is prevalent in the community and associated with increased of ostial pulmonary vein diameter. We investigate pulmonary vein diameter in its relationship to left ventricular hypertrophy.Methods and Results: Ostial pulmonary veins divided into four parts, left superior (LS), right superior (RS), left inferior (LI), and right inferior (RI), were assessed by spiral multisliced computed tomography (MSCT) in 46 sinus rhythm subjects. LVH was analyzed by measuring the thickness of interventricular septum by MSCT. There were 23 patients with LVH, and the rest were normal. According to Pearson correlation analysis, we found a significant positive correlation between the degree of LVH and ostial diameter of RS, RI, and LS (p<0.05).Conclusion:Left ventricular hypertrophy is associated with right superior, right inferior and left superior pulmonary veins dilatation.
Sensitivitas Barorefleks pada Penderita Penyakit Jantung Koroner yang Menjalani Intervensi Koroner Perkutan Cholid Tri Tjahjono; Muhammad Munawar; RWM Kaligis; Idris Idham
Jurnal Kardiologi Indonesia Vol. 28, No. 6 November 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i6.207

Abstract

Background.Autonomic dysfunction contributes to incidence of ventricular arrhythmias and sudden cardiac death in patients with coronary artery disease (CAD). Revascularization, for example percutaneous coronary intervention (PCI), is intended to improve myocardial perfusion. Besides that, PCI is considered to improve autonomic dysfunction. This study is aimed at assessing baroreflex sensitivity (BRS) in patients with CAD before and after PCI.Methods. Patients with angiographically having coronary stenoses = 50% who underwent coronary angioplasty at the catheterization laboratorium of National Cardiovascular Center Harapan Kita, Jakarta, were included in this study. Baroreflex sensitivity was calculated by administering nitroglycerin 300 µg intra aortic before and after PCI.Results.Subjects comprise of 8 (42%) male and 11 (58%) female, aged 57.5 ± 9.3 year old. Most of subjects had dyslipidemia (57%), were smoker (42%), had hypertension (42%) and only 3 (16%) had diabetes mellitus. Nine (47%) of subjects had previous history of myocardial infarction. Medications suspected affecting baroreflex sensitivity, which were used by the time of study included nitrate (63%), beta-blockade (58%), and calcium antagonist (32%). Mean value of baroreflex sensitivity pre-PCI and post-PCI were 2,51+3,23 ms/mmHg and 1,96+1,61 ms/mmHg (p=0,412), subsequently. Multivariate analysis with logistic regression showed that nitrate has significant effect on decreased BRS soon after PCI (p=0,023; CI 95% 1,496-216,62;OR 18,00).Conclusion. In patients with Coronary Artery Disease, immediately after percutaneous coronary intervention, barorefelex sensitivity was decreased. Nitrate has significant effect on alteration of barorefelex sensitivity.
Disinkroni Ventrikel Pada Pacu Jantung Permanen Dengan Elektroda di Apex dan Alur Keluar Ventrikel Kanan: Evaluasi Menggunakan Tissue Doppler Imaging Wisnoe Pribadi; Manoefris Kasim; Iwan Dakota
Jurnal Kardiologi Indonesia Vol. 28, No. 6 November 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i6.208

Abstract

Background : Pacemaker lead implantation at right ventricular apex (RVA) or right ventricular outflow tract (RVOT) have different haemodynamic consecuences, due to ventricular dyssynchrony difference. Tissue Dop-pler Imaging (TDI) clearly shown ventricle dyssynchrony, this modality is better than convensional echo. This research was performed using TDI to describe ventricle dyssynchrony in RVA and RVOT pacing.Method and Result: Twenty four patients with VVI/VVIR pacemaker in-serted at the Catheterization Laboratory National Cardiac Centre Harapan Kita Hospital were evaluated using TDI modality for ventricle dyssynchrony. Subject characteristic consist of 13 men (54,8%) and 11 (45,8%) women, with average of age were 61,38 ± 12,41 years. Base rhythm were Sick Sinus Syndrome/SSS (37,5%) and Total Atrioventricular Block/TAVB (62,5%). The duration of implantation was 24,83 ± 16,88 months, with minimal duration of pacing 1 month and maximal duration 63 months. The average of ventricular ejection fraction was 0,45±0,15. Chi Square ana-lyze have shown that there were no difference dyssynchrony between RVA and RVOT pacing, p=0,408 for inter ventricular delay and p=0,423. for intra ventricular delay. QRS duration after pacing have shown signifi-cant difference between the two groups (p=0.01).Conclusion : There were no difference in ventricular dyssynchrony be-tween RVA and RVOT pacing, but QRS duration at the RVOT pacing is significantly shorter than RVA pacing.
Adiponektin Pada Sindrom Koroner Akut Studi di Pusat Jantung Nasional ”Harapan Kita” Bagus Ari Pradnyana; Nani Hersunarti; Santoso Karo Karo
Jurnal Kardiologi Indonesia Vol. 28, No. 6 November 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i6.209

Abstract

Objective.The association of hypoadiponectinemia and the development of obesity-related condition, including dislipidemia and coronary heart dis-ease (CHD) has been known. The results of some studies on hypoadiponectinemia as a predictor of coronary artery disease is still con-troversial. The aim of this study is to examine whether the hypo-adiponectinemia can be used as a predictor of total MACE among patients with acute coronary syndrome (ACS).Patients and methods. This a cohort study recruits 80 patients with Acute Coronary Syndrome in Emergency Department of National Car-diovascular Center Harapan Kita, Jakarta. They were followed for a me-dian follow-up of 81.48 days; the end points are re-infarct, recurrent is-chemia, heart failure and all causes of mortality. The mean age is 54.51 ± 9.02 year. Sixty-three patient is male (78.8%) and 17 is female (21.3%). The mean total cholesterol is 202.14 ± 45.10 mg/dl, mean HDL is 36.75 ± 13.56 mg/dl, mean LDL is 125.42 ± 39.26 mg/dl and mean triglycerides is 182.61 ± 104.40 mg/dl. The most common risk factors are hyperten-sion (51,3%) and smoker (53,8%). The mean adiponectin level is 8.15 ± 3.67 ug/ml. On multivariate analysis, hypoadiponectinemia (< 5.34 ug/ml) tends to associates with total MACE, though statistically insignificant, with RR of 4.33 (95% CI: 0.86 – 21.8; P = 0.075).Conclusions. These results suggest that hypoadipoadiponectinemia is not significantly associates with total MACE in those ACS patients.
Pericardial Cyst in a Neonate Dicky A Hanafy; Puti Sarah Saus; Poppy S Roebiono; Ganesja M Harimurti
Jurnal Kardiologi Indonesia Vol. 28, No. 6 November 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i6.210

Abstract

Pericardial cyst is a rare entity, often discovered incidentally on routine chest radiographs. Some studies reported an incidence of about 1:100.000. Symptomatic cysts presenting in the neonatal period are very rare. Most of the patients are asymptomatic, but can cause symptoms when they undergo complications or on account of their large size. We describe the case of a neonate presenting with tachypneau where a pericardial cyst was diagnosed with echocardiography and computer tomography, the cyst was successfully resected with open heart surgery.
Total Anomalous Pulmonary Venous Drainage Sunu Budhi Raharjo; Poppy S Roebiono; Vickry Wahidji; Anna Ulfah Rahajoe
Jurnal Kardiologi Indonesia Vol. 28, No. 6 November 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i6.211

Abstract

Total Anomalous Pulmonary Venous Drainage (TAPVD) pertama kali dilaporkan oleh Friedkowsky pada tahun 1868, namun baru pada tahun 1942 TAPVD dikenal sebagai sebuah entitas penyakit. Penyakit ini jarang terjadi, insidensinya sekitar 1-3% dari semua penyakit jantung bawaan (PJB) atau sekitar 0,008% dari seluruh bayi lahir hidup.Di Pusat Jantung Nasional Harapan Kita (PJN-HK), selama tahun 2006 terdapat 8 kasus (5 laki-laki dan 3 perempuan) atau sekitar 0,7% dari total kasus PJB. Pasien dengan TAPVD sebagian besar akan menunjukkan gejala pada usia <1 tahun, dan bila tidak segera dikoreksi maka 80% kemungkinan akan meninggal pada usia 1 tahun. Sementara pasien yang tidak menunjukkan gejala pada umur <1 tahun biasanya mempunyai prognosis yang relatif lebih baik, dan operasi koreksi bisa dilakukan elektif saat usia kanak-kanak.Terapi medikamentosa, terutama ditujukan untuk mengatasi gagal jantung, dan umumnya cukup membantu. Namun pada kasus TAPVD dengan obstruksi atau dengan hipertensi pulmonal, terapi medikamentosa ini tidak meningkat-kan angka survival. Kami sajikan tiga kasus TAPVD sebagai ilsutrasi kasus.
Infark Miokard Ventrikel Kanan Starry H Rampengan; Eko Antono
Jurnal Kardiologi Indonesia Vol. 28, No. 6 November 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i6.212

Abstract

Infark miokard merupakan penyebab utama kematian pada orang dewasa di seluruh dunia. Infark ventrikel kanan (right ventricle, RV) biasanya menyertai infark inferior pada 30-50% kasus, dan infark anterior pada 10% kasus. Beberapa komplikasi dapat menyertai infark inferior yang disertai infark RV, komplikasi ini dapat menimbulkan kematian. Berikut akan disampai-kan contoh kasus dengan permasalahnya, dan pembahasan tentang tatalaksana yang benar.
Efusi Perikardium Tuberkulosis Budiyanto Nagawidjaya
Jurnal Kardiologi Indonesia Vol. 28, No. 6 November 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i6.213

Abstract

Tuberkulosis merupakan salah satu penyebab perikarditis, yang gejala awalnya hanya demam. Tetapi dalam perjalanan penyakitnya, perlahan-lahan menjadi progresif karena timbulnya efusi perikardium yang dapat mengakibatkan tamponade jantung. Karena proses ini berlangsung perlahan, acap kali diagnosisnya terlambat. Terapi dengan anti tuberkulosis memberikan prognosis yang baik. Insidensi efusi perikardium tuberkulosis sekitar 1% dari jumlah kasus tuberkulosis, dengan angka kematian berkisar 3–40%. Efusi perikardium yang berlanjut menjadi tamponade jantung dan perikarditis konstriktif merupakan 2 penyebab kematian tersering. Oleh karenanya, semua pasien perikarditis tuberkulosis dianjurkan dirawat di rumah sakit, untuk observasi kemungkinan terjadi efusi perikardium atau tamponade jantung yang mengancam kehidupan.

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