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Prevalence and Characteristics of Low Back Pain among Productive Age Population in Jatinangor Novitasari, Dini Diwayani; Sadeli, Henny Anggraini; Soenggono, Arifin; Sofiatin, Yulia; Sukandar, Hadyana; Roesli, Rully M. A.
Althea Medical Journal Vol 3, No 3 (2016)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (174.123 KB)

Background: Low back pain is one of the global health issues which prevalence is high among productive ages. It oftentimes corresponds with oneâs physical activity during work . The purpose of this study was to determine theprevalence and characteristics of low back pain among productive age population in Jatinangor, West Java, Indonesia.Methods: This study was a cross-sectional descriptive study conducted during the period of August to October 2014 in the three villages in Jatinangor, West Java, Indonesia. In order to determine the demographic data and history of low back pain in the last three months, about 1075 productive age populations were selected through validated questionnaire as the secondary data. These data consisting of 310 subjects were then described according to the pain characteristics and physical activity during work.Results: During three months of examination, s the prevalence of low back pain was 38.4%, with the average age 50â59 years old. Furthermore, about 22.3% subjects were indicated chronic low back pain. The most prevalent qseverity of the pain was dull pain (29.4%), followed with pins and needles pain (23.1%), As the intensity of the pain increased, there was a tendency of increasing interference in daily activities. Static posture was also the most frequent physical activity during work (53.2%).Conclusions: The prevalence of low back pain is more than one third (38.4%) among productive age populations in Jatinangor, West Java, Indonesia.[AMJ.2016;3(3):468â75]DOI: 10.15850/amj.v3n3.863

Familial Analysis of Patients with Hypertension in Jatinangor, West Java, Indonesia Hayati, Keumala; Sofiatin, Yulia; Rahayuningsih, Sri Endah; Roesli, Rully M.A.
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (740.112 KB)

Background: Hypertension is a disease that is influenced by genetic factors, although the single gene affecting the occurrence of the disease has not been yet discovered. Genetic analysis and familial analysis on hypertension are needed to be done but genetic analysis needs substantial fund, and familial analysis on hypertension has been never done in community. Besides sharing the genetic factors, family also shares similar environment and life style. Latest study showed that the association between genetic and environmental factors can affect the phenotype of chronic disease suchas hypertension. The study was aimed to explore the family history contribution of patients with hypertension in Jatinangor.Methods: This was a descriptive-quantitave study. The subjects were 283 hypertensive patients in Jatinangor with complete data of family history. The data was retrospectively obtained from secondary data of a previous study conducted in Community Health and Well-ness Study Center, Faculty of Medicine, Universitas Padjadjaran titled Epidemiology of Hypertension and Albuminuria in Jatinangor 2014. Familial analysis conducted in this study was modified trios analysis.Results: In this modified trios analysis, there was only 20% of total patients with hypertension who have history of hypertension in two generations of their family. The proportion of patients with hypertension who have history of hypertension in one generation of their family was greater. More than 45% from the total 283 patients with hypertension analyzed in this study have family history of hypertension.Conclusions: Familial analysis using modified trios analysis showed similar results with the study conducted using other genetical analysis.

Cardiovascular Risk Profile in Health Cadres in Jatinangor, West Java Badai Bhatara Tiksnadi; Rien Afrianti; Yulia Sofiatin; Arif Ridha; Faris Yuflih Fihaya; Rully M. A. Roesli; Mohammad Rizki Akbar
Althea Medical Journal Vol 6, No 2 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran

Background: Cardiovascular disease has very high morbidity and mortality, therefore, prevention of this disease becomes a national priority in the health programs. Health cadres, as an agent in community primary prevention, should have a good health condition. This study aimed to describe the cardiovascular risk profile in health cadresin Jatinangor, West Java.Methods: This was a cross-sectional study, conducted in Cilayung Village, Jatinangor, in September 2018. Consecutive sampling was performed on 20 health cadres aged 25 - 64 years old who did not have previous cardiovascular events such as coronary heart disease or stroke. Clinical data were collected consisting of blood pressure, body mass index (BMI), random blood glucose, history of diabetes mellitus, physical activity and active smoking habits. Cardiovascular risk was assessed using Jakarta cardiovascular scores and European Relative Risk Score.Results: Only 17 of 20 health cadres fulfilled the inclusion criteria with a systolic and diastolic blood pressure of 133.5±27.8 mmHg and 81.1±14.8 mmHg, respectively, and BMI of 27.4±5.3 kg/m2.The risk of cardiovascular disease in healthy cadres was at low (47.1%), moderate (41.2%) and high risk (11.7%). The average of the European Relative Risk score was 1.88±0.9. BMI >30 has a 40% high risk of cardiovascular disease.Conclusions: Most of the health cadres in Jatinangor, West Java have a low and moderate risk of cardiovascular disease, even though there is a small percentage that is at a high risk. The awareness for prevention and management programs for risk factors needs to be raised among health cadres. .

Sweet Taste Threshold among Medical Students with Family History of Diabetes Mellitus Nasya Aisah Latif; Yulia Sofiatin; Maya Kusumawati; Rully Marsis Amirullah Roesli
Althea Medical Journal Vol 7, No 4 (2020)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v7n4.1940

Background: Diabetic patients have low sensitivity towards sweet taste, thus consuming more sugar. A young adult with family history of diabetes mellitus (FHD) who lives with diabetic parents may have an increased risk of overconsumption of sugar due to a similar dietary pattern, leading to diabetes. This study aimed to explore the difference in the sweet taste threshold (STT) between students with and without a family history of diabetes mellitus.Methods: This cross-sectional study was conducted in October –November 2018 on Class 2018 medical students living in a student dormitory who were divided into those with family history of diabetes (FHD) and those without it (non-FHD). Family history of diabetes and other known diseases were self-reported. The three-Ascending Forced Choice method was used to determine the sweet recognition threshold. Mann-Whitney analysis was used to compare the sweet taste thresholds between the two groups.Result: A total of 183 subjects participated in this study. The non-FHD group had a higher rank of sweet taste threshold than subjects in the FHD group (94.21 vs 81.16), albeit insignificant (p=0.192). Interestingly, the modes of best estimation threshold (BET) for non-FHD group was than the FHD group (0.067 M vs 0.043 M).Conclusion: The BET for students without family history of diabetes is higher than those with family history of diabetes. It is imperative that low sugar consumption campaign should also aim young people without FHD.

Qualitative Analysis of Establishing Diagnosis and Management of Hypertension from Patient’s Perspective in Jatinangor Yulia Sofiatin; Nazmun Lailah; Trully Deti Rose Sitorus; Rully M. A. Roesli
Althea Medical Journal Vol 5, No 4 (2018)
Publisher : Faculty of Medicine Universitas Padjadjaran

Background: Blood pressure control is necessary to prevent complications in patients with hypertension. A previous study in Jatinangor showed the failure of controlling blood pressure even with pharmacological treatment. Proper diagnosis and effective management are considered to influence the condition. This study was performed to describe the process of establishing diagnosis and management for hypertension from the patient’s perspective in Jatinangor.Methods: A phenomenological approach was used. Data were collected through semi-structured questions in focus group discussions (FGDs) led by a moderator. Participants of FGDs were patients with hypertension who had undergone antihypertensive drugs therapy based on a previous study, and were invited by the local health cadres. The study was held in two villages in Jatinangor, namely Hegarmanah and Cilayung in the period of July to August 2015. Data were presented as narration and figures.Results: There were five and eight hypertensive participants for Hegarmanah and Cilayung villages FGD, respectively. Diagnosis of hypertension in FGD participants was not only confirmed by doctors but also other health professionals, due to various accessibilities to health care facilities. Diagnosis establishment and management of hypertension were not following the protocol. Education on pharmacological and non-pharmacological management was provided by health professionals, however still lacked details and was not reviewed on every visit, resulting in a lack of compliance. Conclusions: Process of establishing diagnosis and management of hypertension from the patient’s perspective in Jatinangor is unfortunately not following the protocol, thus may influence the blood pressure control outcome.

Familial Analysis of Patients with Hypertension in Jatinangor, West Java, Indonesia Keumala Hayati; Yulia Sofiatin; Sri Endah Rahayuningsih; Rully M.A. Roesli
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (740.112 KB)

Background: Hypertension is a disease that is influenced by genetic factors, although the single gene affecting the occurrence of the disease has not been yet discovered. Genetic analysis and familial analysis on hypertension are needed to be done but genetic analysis needs substantial fund, and familial analysis on hypertension has been never done in community. Besides sharing the genetic factors, family also shares similar environment and life style. Latest study showed that the association between genetic and environmental factors can affect the phenotype of chronic disease suchas hypertension. The study was aimed to explore the family history contribution of patients with hypertension in Jatinangor.Methods: This was a descriptive-quantitave study. The subjects were 283 hypertensive patients in Jatinangor with complete data of family history. The data was retrospectively obtained from secondary data of a previous study conducted in Community Health and Well-ness Study Center, Faculty of Medicine, Universitas Padjadjaran titled Epidemiology of Hypertension and Albuminuria in Jatinangor 2014. Familial analysis conducted in this study was modified trios analysis.Results: In this modified trios analysis, there was only 20% of total patients with hypertension who have history of hypertension in two generations of their family. The proportion of patients with hypertension who have history of hypertension in one generation of their family was greater. More than 45% from the total 283 patients with hypertension analyzed in this study have family history of hypertension.Conclusions: Familial analysis using modified trios analysis showed similar results with the study conducted using other genetical analysis.

Prevalence and Characteristics of Low Back Pain among Productive Age Population in Jatinangor Dini Diwayani Novitasari; Henny Anggraini Sadeli; Arifin Soenggono; Yulia Sofiatin; Hadyana Sukandar; Rully M. A. Roesli
Althea Medical Journal Vol 3, No 3 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (184.32 KB)

Background: Low back pain is one of the global health issues which prevalence is high among productive ages. It oftentimes corresponds with one’s physical activity during work . The purpose of this study was to determine theprevalence and characteristics of low back pain among productive age population in Jatinangor, West Java, Indonesia.Methods: This study was a cross-sectional descriptive study conducted during the period of August to October 2014 in the three villages in Jatinangor, West Java, Indonesia. In order to determine the demographic data and history of low back pain in the last three months, about 1075 productive age populations were selected through validated questionnaire as the secondary data. These data consisting of 310 subjects were then described according to the pain characteristics and physical activity during work.Results: During three months of examination, s the prevalence of low back pain was 38.4%, with the average age 50–59 years old. Furthermore, about 22.3% subjects were indicated chronic low back pain. The most prevalent qseverity of the pain was dull pain (29.4%), followed with pins and needles pain (23.1%), As the intensity of the pain increased, there was a tendency of increasing interference in daily activities. Static posture was also the most frequent physical activity during work (53.2%).Conclusions: The prevalence of low back pain is more than one third (38.4%) among productive age populations in Jatinangor, West Java, Indonesia.[AMJ.2016;3(3):468–75]DOI: 10.15850/amj.v3n3.863

Survival Analysis of Chronic Kidney Disease Patients with Hemodialysis in West Java. Indonesia, Year 2007 - 2018 Afiatin Afiatin; Dwi Agustian; Kurnia Wahyudi; Pandu Riono; Rully M. A. Roesli
Majalah Kedokteran Bandung Vol 52, No 3 (2020)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v52n3.2124

The prevalence of chronic kidney disease on dialysis or CKD5D is increasing with a significant impact on disease burden in many countries. Patients are usually listed in the national renal registries, which report demographic data, incidence, prevalence, and outcome. The survival rate is an important outcome measure to characterize the impact of treatment in the CKD5 patient population in the national and international renal registries. Indonesian Society of Nephrology (InaSN) has the Indonesian Renal Registry program to collect data that was endorsed to monitor dialysis treatment quality in Indonesia. IRR releases an annual report, but there is no survival analysis yet. This study aimed to discover the five-year survival rate of CKD5D patients in West Java between 2007–2018 and its factor based on the IRR database. A retrospective cohort study was performed by gaining all patients' data from the IRR database, then data on all of the patients from West Java province who completed a 5-year follow-up on December 31, 2018. Kaplan-Meier analysis and Cox proportional hazard's model were used to analyze the risk factors. There were 3,199 data included in this study. In total, the 1, 2, 3, 4, and 5 year survival rates are 82%, 70%, 62%, 58%, and 55 %, respectively. Patients whose age is above 55 years and with unknown underlying kidney disease have a worse survival rate with a hazard ratio of 1.28 and 1.50, respectively. Further exploration of IRR data will provide better information on dialysis treatment in Indonesia. Ketahanan Hidup Pasien Penyakit Ginjal Kronis dengan Hemodialisis di Jawa Barat Indonesia tahun 2007-2018Prevalensi penyakit ginjal kronis pada dialisis atau PGK5D meningkat dan memberi beban penanganan penyakit di banyak negara. Pasien biasanya terdaftar dalam register ginjal nasional yang melaporkan data demografis, insiden, prevalensi dan luaran klisis. Tingkat ketahanan hidup merupakan parameter penting dalam registrasi ginjal untuk menggambarkan kualitas terapi pada populasi pasien PGK stadium 5. Perhimpunan Nefrologi Indonesia (Pernefri) memiliki program Registri Ginjal Indonesia yang disebut Indonesian Renal Registry (IRR) untuk mengumpulkan data pasien PGK5D untuk memantau kualitas pengobatan dialisis di Indonesia. IRR merilis laporan tahunan tetapi belum dilengkapi dengan analisis ketahanan hidup. Tujuan penelitian ini adalah mengetahui angka ketahanan hidup lima tahun pasien PGK5D di Jawa Barat antara tahun 2007-2018 dan faktor risikonya berdasarkan basis data dari IRR. Studi kohort retrospektif dengan mengambil semua data pasien dari basis data IRR kemudian ditentukan data pasien Jawa Barat yang lengkap dan di follow up selama 5 tahun pada 31 Desember 2018. Analisis Kaplan-Meier dan model proporsional hazard Cox digunakan untuk menganalisis faktor risiko. Subjek berjumlah 3199 data yang dimasukkan dalam penelitian ini. Kesimpulannya, angka harapan hidup satu, 2, 3, 4, dan 5 tahun berturut-turut adalah 82%, 70%, 62%, 58%, dan 55%. Usia lebih dari 55 tahun dan penyakit ginjal yang mendasari memiliki kelangsungan hidup yang lebih buruk dengan hazard ratio 1,28 dan 1,50. Eksplorasi lebih lanjut dari data IRR akan memberikan informasi yang lebih baik tentang perawatan dialisis di Indonesia.

Kesiapan Masyarakat dalam Melaksanakan dan Memanfaatkan Posyandu Penyakit Tidak Menular di Desa Cilayung dan Cipacing, Kecamatan Jatinangor Yulia Sofiatin; Rully M.A. Roesli
Global Medical & Health Communication (GMHC) Vol 5, No 2 (2017)
Publisher : Universitas Islam Bandung

Pengendalian hipertensi dan penyakit tidak menular (PTM) memerlukan kerja sama pasien karena pilar utama pengendalian PTM adalah pengetahuan penderita dan kepatuhan dalam menjalankan upaya pengendaliannya. Sampai saat ini pemberian edukasi di sarana kesehatan tidak efektif sehingga diperlukan upaya lain seperti kelompok dukungan pasien dan peningkatan kemampuan masyarakat. Pos pelayanan terpadu (posyandu) PTM merupakan salah satu alternatif. Penelitian ini bertujuan menggali kesiapan kader posyandu dan pasien hipertensi mengenai kemungkinan pelaksanaan posyandu khusus PTM. Telah dilakukan diskusi kelompok terarah (DKT) terhadap dua kelompok (kader dan penderita) di Desa Cilayung dan Cipacing serta 1 (satu) sesi wawancara mendalam terhadap Kepala Puskesmas Kecamatan Jatinangor, Sumedang pada Maret–April 2017 dengan tingkat partisipasi peserta cukup baik. Keempat kelompok menyatakan kebutuhan terhadap posyandu PTM dengan aktivitas selain pemantauan tekanan darah dan berat badan yang dibutuhkan adalah penyuluhan mengenai perbaikan gaya hidup dan kepatuhan berobat. Kader Desa Cipacing siap melaksanakan penyuluhan jika telah mendapat pelatihan, tetapi kader Desa Cilayung menginginkan penyuluh dari luar lingkungan mereka. Terdapat kebutuhan kemudahan mendapatkan obat karena pengambilan obat di puskesmas dirasakan membutuhkan biaya transportasi yang cukup tinggi. Dapat disimpulkan bahwa masyarakat dan kader merasakan kebutuhan terhadap posyandu PTM, tetapi kesiapan mereka berbeda-beda.COMMUNITY READINESS TO RUN AND UTILIZE INTEGRATED HEALTH POST FOR NON-COMMUNICABLE DISEASE IN CILAYUNG AND CIPACING VILLAGES, JATINANGORThe main pilars of non-communicable diseases (NCDs) management are patient’s awareness, knowledge and compliance. At present, education by health provider in health facilities has been proven to be not effective that other measures such as patient support group and community empowerement are needed. The options is through integrated health post (posyandu) for NCD. The aim of this research was to explore the readiness of the community to run and utilize such post. Four sessions of focus group discussions with two groups of health cadres and two groups of people with high blood pressure in Cilayung and Cipacing villages and 1 (one) session of indepth interview towards the Head of Public Health Center (Puskesmas) at Jatinangor, Sumedang, Indonesia were held on March–April 2017 with high participations. Each group expresses the needs of patient support group and community empowerement through regular integrated health post for NCDs. Schedulled screening and mass education especially for life style modification and drug used are urgent. Health cadres of urban community are ready to lead the activities, while those from rural area ask for formal educators. Drug dispensing at public health center is favourable due to expensive transportation to primary health care. In conclusion, communities in Jatinangor need integrated health post for NCD to assist them to manage their blood pressure and other NCDs although their readinesses were vary.

Dynamic Interaction Between Organellas In the Management of Cytosolic Calcium Huvecs Exposed to 22 mM Glucose With Different Period Exposure Olly Indrayani PWM; Djanggan Sargowo; Mochammad Aris Widodo; Rully MA Roesli; S Sumarno
Jurnal Kardiologi Indonesia Vol. 28, No. 6 November 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i6.205

Background.In our previous research, when cell culture were exposed to high glucose, this will cause the increase of H2O2. At the exposure to 22 mM glucose on 3rd day, the increase of H2O2 that induced the activation of Phospholipase C (PLC) have caused 1P3 (Inositol tri-phosphate) mobilizing the release of Ca²+ from the depo Endoplasmic reticulum (ER). Thus, causing the increase of cytosolic Ca²+. Giving thapsigargin (TG) will cause significant increase in Cytosolic Ca²+ so that the most contribution to the increasing of Cytosolic Ca²+ derives from the ER . On the 7th day exposure, H2O2 played the same role as TG, causing direct incease in Cytosolic Ca²+ and an addition of Ca²+ free/buffer ethyleneglyco bis (ßaminoethyl ether).&NNN’N’– tetraacetic acid (EGTA) caused significant decrease of cytosolic Ca²+ basal and the greatest contribution to the increase of cytosolic Ca²+ on the 7th day, comes from extracellular. Administrating Cyclosporin A (CSA) 10 µM on the 9th day, caused significant decreasing on cytosolic Ca²+ basal, the ability of CSA in decreasing Ca²+ basal concentration was less than the 3rd and 7th days. At a high glucose condition with different length of exposure, a change of new cytosolic Ca²+ homeostatic regulation occurred and this enable a change in the dynamic interaction among ER, extracellular and mitochondria.Method.HUVECs culture exposed to 22 mM glucose for 3, 7 and 9 days. The cells were incubated with FURA2-AM. The evaluation of fluorescence cytosolic Ca²+ was done by epifluorescence Nikon digital camera-computerized analyser. To measure the cytosolic Ca²+ concentration we use Histogram Image Corel Draw Photo Paint 12.Result. Exposure to glucose 22mM on the 3rd day (65.4 ± 12.2) it showed the increase of cytosolic Ca²+ by giving Ca²+ free/EGTA 1 mM and CSA 10 mM caused the decrease of cytosolic Ca²+ (33.2 ± 4.47) TG1µM and CSA caused the decrease of cytosolic Ca²+ basal (53.07 ± 2.75) and Ca²+ -free/EGTA, TG and CSA (68.59 ± 5.71). On the 7th day exposure (92.74 ± 7.66) the decrease of cyto -solic Ca²+ basal occurred at the giving of Ca²+ -free/EGTA, TG (50.52 ± 9.23). EGTA and CSA (45.59 ±6.2). TG and CSA (73.55 ± 7.30), Ca²+ -free/EGTA and TG much more decrease the concentrate of cytosolic Ca²+ basal (17.58 ±4.5). On the 9th day of exposure to glucose (72.32 ±7.46), the giving of Ca²+ -free/EGTA, TG and CSA(35.76 ± 5.25) have caused the decrease of cytosolic Ca²+ basal. Conclusion.HUVECs culture exposed to 22mM glucose will cause the increase in H2O2and cytosolic Ca²+ basal. ER, mitochondria and extracellular regulate the Cytosolic Ca²+ and a dynamic interaction occurred among them to obtain a new homeostatic.

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