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Contact Name
Raymond Pranata
Contact Email
raymond_pranata@hotmail.com
Phone
+6282112918892
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ijc@inaheart.org
Editorial Address
Editorial Office: Heart House, Jalan Katalia Raya No. 5, Kota Bambu Utara West Jakarta, 11430 - Indonesia Telephone: +62 21 5681149, Fax: +62 21 5684220 Email: ijc@inaheart.org
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Dki jakarta
INDONESIA
Indonesian Journal of Cardiology
ISSN : 28303105     EISSN : 29647304     DOI : -
Core Subject : Health,
Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other health professionals for scientific articles in the cardiovascular field. All articles (research, case report, review article, and others) should be original and has never been published in any magazine/journal. Prior to publication, every manuscript will be subjected to double-blind review by peer-reviewers. We consider articles on all aspects of the cardiovascular system including clinical, translational, epidemiological, and basic studies. Subjects suitable for publication include but are not limited to the following fields: Acute Cardiovascular Care Arrhythmia / Cardiac Electrophysiology Cardiovascular Imaging Cardiovascular Pharmacotherapy Cardiovascular Public Health Policy Cardiovascular Rehabilitation Cardiovascular Research General Cardiology Heart Failure Hypertension Interventional Cardiology Pediatric Cardiology Preventive Cardiology Vascular Medicine
Articles 9 Documents
Search results for , issue "Vol. 36, No. 4 Oktober - Desember 2015" : 9 Documents clear
Kontroversi peran studi elektrofisiologi pada sindrom brugada Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 36, No. 4 Oktober - Desember 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i4.500

Abstract

Sindrom Brugada adalah suatu abnormalitas sistem listrik jantung yang merupakan predisposisi terjadinya takikardia ventrikel dan hilang kesadaran. Takikardia ventrikel dapat berhenti spontan dan pasien pulih dari sinkop lalu berobat dengan keluhan sinkop, atau takikardia berdegenerasi menjadi fibrilasi ventrikel (FV)dan menyebabkan kematian jantung mendadak. Oleh karena itu sangat penting mengenal gambaran EKG sindrom Brugada lalu melakukan stratifikasi risiko yang cermat.Salah satu yang menjadi perdebatan hangat adalah stratifikasi risiko sindrom Brugada melalui tindakan studi elektrofisiologi (SEF). Nilai prediktif induksi aritmia ventrikel saat SEF masih kontroversial. Studi yang melibatkan 408 pasien sindrom Brugada tanpa riwayat henti jantung menunjukkan bahwa pasien dengan indusibilitas FV memiliki risiko kematian jantung mendadak karena FV enam kali lipat dalam pengamatan 2 tahun.1 Akan tetapi studi multisenter dari Eropa,2, 3 Jepang4, 5 dan beberapa metaanalisis6, 7 tidak menunjukkan hasil yang positif sehingga indikasi SEF untuk stratifikasi risiko sindrom Brugada hanya IIb pada tahun 2013 (Gambar 1). Metaanalisis8 yang lain memperlihatkan hasil yang positif yaitu ketika presentasi klinis pasien sindrome Brugada dipisahkan antara sinkop dan asimtomatik dalam analisanya.
Peranan Mitral Leaflet Separation Index (Mlsi ) dalam Menentukan Severitas Stenosis Mitral I Made Junior Rina Artha; Amiliana M Soesanto; Indriwanto Sakidjan; Ganesja M Harimurti
Jurnal Kardiologi Indonesia Vol. 36, No. 4 Oktober - Desember 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i4.501

Abstract

Objective. To Correlate MLSI with 3-D mitral valve area (MVA) planimetry in determining mitral stenosis (MS) severity.Background. Mitral Stenosis (MS) is still a major problem in cardiology, and causes of morbidity dan mortality worldwide. Echocardiogrphy plays an important role in assessing mitral stenosis severity. Mitral leaflet separation index (MLSI) is one of simple method that can be used in peripheral by using common ultrasound to assess the severity mitral stenosis.Methods. We employed a cross sectional study. Mitral stenosis patients who referred for evaluation echocardiography in National Cardiac Center Harapan Kita from April to September 2011. MLSI was obtained by averaging the maximal leaflet separation distance at the tips in diastole in parasternal long-axis and apical four- chamber views. 3-Dimensional (3-D) mitral valve area (MVA) planimetry as a reference. The only exclusion criteria was severe calcification and poor echo window. Echocardiography examination using Philips E33i.Results. Seventy six consecutive patients were enrolled, 5 subjects were excluded from study because of severe calcification and poor echo window. Proportion of woman is 73.2 % and mostly in age group < 40 years old (43.7 %). Severe mitral stenosis was dominate the subject, 47 subject (66.2 %), moderate was 19 subject (26.8 %), and mild only 5 subjects (7.0 %). Analysis with Spearman correlations obtained a good correlation with r = 0.70, p < 0.001, good correlation was found in sinus rhythm with r = 0.78, p < 0.001 and atrial fibrillation with r = 0.79, p < 0.001. MLSI less than 0.69 cm predicted severe MS with 85 % sensitivity and 82.4 % specificity.Conclusions. Mitral leaflet separation index (MLSI) has a good correlation with 3-D MVA planimetry. MLSI less than 0.69 cm can estimate severe SM.
Pemanfaatan Indole-3-Carbinol Sebagai Inhibitor Flavin Monooxygenase 3 (Fmo 3) Dalam Upaya Prevensi Aterosklerosis Bagus Indra Kusuma; Brenda Desy Romadhon; Silvi Ahmada Chasya; Hazmi Dwinanda Nurqistan; Lusi Padma Sulistianingsih Mata
Jurnal Kardiologi Indonesia Vol. 36, No. 4 Oktober - Desember 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i4.502

Abstract

Cardiovascular disease is the leading cause of death in the world, reaching 30% of all mortality. The most common cause of cardiovascular disease is the formation of atherosclerotic plaque in blood vessels. Treatment has been done to overcome atherosclerosisonly curative and still no preventive. Processes that play a role in the formation of atherosclerotic plaque is very complex and one of the causes deposition of plaques is the formation of the compound trimethylamine oxide (TMAO) in the body. TMAO that has produced can increase the accumulation of cholesterol in macrophages so that increasing the formation of foam cells in the arterial wall. These compounds are derived from trimethylamine (TMA), which is converted into TMAO by enzyme flavin monooxygenase (FMO). FMO enzyme that is able to make an impact in the formation of TMAO is flavin monooxygenase 1 (FMO1) and flavin monooxygenase 3 (FMO3). However, FMO3 showed activity ten times greater than FMO1 in turning TMA into TMAO. Indole-3-carbinol can be a role for this enzyme inhibitor so that the therapeutic use of indole-3-carbinol is expected to inhibit TMAO. Therefore, the authors propose the use of research in the form of indole-3-carbinol as an inhibitor of flavin monooxygenase 3 (FMO3) in atherosclerosis prevention efforts. The study design used was pure experimental research design (true experimental design) with post test only randomized control group design. Mice (Mus musculus) males were treated indole-3-carbinol and then is given atherogenic diet for the provision of intravenous adrenaline 0.00084 mg / 20 gBW and egg yolks 0.2 cc / day. The treatment group consisted of a positive control, negative control, treatment A (10 mg / kg BW of indole-3-carbinol), B (200 mg / kg BW I3C), and C (500 mg / kg BW I3C). The data observed in the form of cholesterol, foam cell histopathological picture of the aorta and the density of the band FMO3 activity. Blood cholesterol levels showed a decrease in accordance with increase in dose. Cholesterol control of negative group, positive, A, B and C respectively of 119.4 ± 28.94 mg / dL, 246 ± 8.52 mg / dL, 224 ± 15.30 mg / dL, 170.6 ± 12.54 mg / dL, and 154.8 ± 14.46 mg / dL (p <0.05). Histopathologic features foam cell in the aorta of mice showed an improvement with the increase in dose. FMO3 enzyme activity also showed a decrease when compared to the positive control in the optical density relative scale along with rising doses of indole-3-carbinol given. This shows that the use of indole-3-carbinol is very effective in atherosclerosis prevention efforts.
Pengaruh Trimetazidine Terhadap Jumlah Netrofil Pasca IKPP Taka Mehi; Yoga Yuniadi; Nur Haryono
Jurnal Kardiologi Indonesia Vol. 36, No. 4 Oktober - Desember 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i4.503

Abstract

Background: Reperfusion strategy, either with thrombolytic or Primary Percutaneous Coronary Intervention (PPCI), is the core treatment for Acute ST-Segment Elevation Myocardial Infarct (STEMI). The goal of PPCI is to restore the patency of infarcted epicardial artery and establish microvascular reperfusion as soon as possible so that necrotic myocardial area can be reduced. However, successful restoration of infarcted epicardial artery is not always followed by enough reperfusion to the microvascular part. Trimetazidine can reduce neutrophil which was mediated by tissue trauma during ischemic heart condition. Unfortunately, its influence over neutrophil accumulation in acute STEMI patients which undergo PPCI is not well understood.Method: There were 68 consecutive-selected acute STEMI patients which undergo PPCI since January 2015 until Juni 2015. They were admitted in emergency department. Peripheral vein blood sampling was taken to measure neutrophil before PPCI was performed. Six hour after PPCI was conducted, another peripheral vein blood sampling was taken for another neutrophil measurement. Neutrophil measurement was performed with Sysmex 2000i. Statistical analysis was performed by using SPSS 17.Result: Among 68 patients, divided in two groups, trimetazidine 28 patients and plasebo 40 patients. There were no differences amount of neutrophils in trimetazidine or plasebo group, before or after PPCI. Neutrophil pre PPCI in trimetazidine vs plasebo group 10.71 ± 3.263 vs 10.99 ± 3.083, p:0,341. Neutrophil post PPCI in trimetazidine vs plasebo group 9.49 ± 3.135 vs 9.92 ± 3.463, p:0,664.Conclusion: There were no reducing amount of neutrophils after trimetazidine was given in patients STEMI which underwent PPCI
Fistula Arteri Koroner, Penyebab Nyeri Dada yang Jarang Ditemukan pada Dewasa : Peran Computed Tomography Angiografi Prima Almazini; Andy Rahman; Dian Yaniarti; Elen Sahara; Celly Anantaria; Manoefris Kasim
Jurnal Kardiologi Indonesia Vol. 36, No. 4 Oktober - Desember 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i4.504

Abstract

Coronary artery fistula, usually congenital in origin, is an abnormal communication between a coronary artery and a cardiac chamber or great vessel. A coronary artery fistula can produce myocardial ischemia from coronary steal phenomenon. First case, a 54-year-old man was found to have a fistula from the left anterior descending coronary artery and right coronary artery to the main pulmonary artery, a rare anomaly. This patient developed chest pain due to myocardial ischemia in the left anterior descending coronary artery distribution for several months before evaluation. The patient was suggested to close the fistula but rejected. Second case, a-57 year-old woman was found to have fistula from left anterior descending coronary artery to main pulmonary artery. Patient presented with chest pain since 6 years ago. The patient was planned to close the fistula transcutaneously. Coronary artery fistulas, though rare, should be considered in the differential diagnosis when an adult patient presents with chest pain. Although coronary angiography is the gold standar diagnostic test for detection of coronary artery fistula, computed tomography angiography may be an alternative test through its good spatial resolution.
Farmakoterapi pada Upaya Berhenti Merokok Diyan Ekawati; Basuni Radi; Feni Fitriani Taufik
Jurnal Kardiologi Indonesia Vol. 36, No. 4 Oktober - Desember 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i4.505

Abstract

Nicotine dependence is a main role in tobacco dependence. Its physiological and psychological effect make smoker difficult to quit, making low success rate in smoking cessation. Combination of different method and continuity will increase smoking cessation success rate. Evidence shown that pharmacotherapy will increase success rate. Guideline’s for smoking cessation endorse physician to use first line pharmacotherapy, but it’s clinical application still limited. Physician should be aware about possibility for side effect. Some randomized controlled trial report major cardiovascular event in first line pharmacotherapy. Recent systematic review report no correlation between first line pharmacotherapy in smoking cessation and major cardiovascular event.
Terapi Resinkronisasi Jantung pada Penanganan Gagal Jantung Hilman Zulkifli Amin; Siska Suridanda Danny
Jurnal Kardiologi Indonesia Vol. 36, No. 4 Oktober - Desember 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i4.506

Abstract

Heart failure (HF) is a worldwide health problem with high prevalence rate. The prevalence is over 23 million worldwide. It is a chronic disease characterized by the inability of the heart to pump an adequate amount of blood to achieve the demand of the different organ systems and/or doing so at increased filling pressures. Despite many recent advances in medication, the rate of people with HF is rising. This health challenges need to be answered properly. One of the new important treatment for HF is cardiac resynchronization therapy (CRT). Many patients with HF also have an abnormality of the heart’s electrical system resulting in asynchronous contraction pattern of heart muscle.The ultimate goal of CRT is to restore synchrony of the heart rhythm in HF patients. CRT implantation in heart failure patients with proper indications like wide QRS complexes, low left ventricular ejection fraction (LVEF), and left bundle branch block (LBBB) has been proved to reduce morbidity, mortality, and also improve symptoms and quality of life (QoL).
Parameter Pengukuran Ventrikel Kiri menggunakan Ekokardiografi Bagian 2 Ario Suryo
Jurnal Kardiologi Indonesia Vol. 36, No. 4 Oktober - Desember 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i4.507

Abstract

1. Fungsi regional ventrikel kiriModel pembagian segmen Vki digunakan dalam praktek klinis sehari-hari. Model pembagian menjadi 17 segmen direkomendasikan untuk menilai perfuso miokardial dengan menggunakan ekokardiografi dan teknik atau modalitas pencitraan lainnya . ( PET Scan atau Cardiac MRI). Model ini dapat dilihat pada gambar 4Model 16 segmen direkomendasikan dipakai secara rutin untuk menilai gerakan dinding Vki karena gerakan endokardial dan penebalan pada bagian apeks Vki sulit untuk bisa dideteksi. Untuk menilai gerakan dinding ini , setiap segmen sebaiknya di dievaluasi menggunakan berbagai pandangan dan 4 tingkatan penilaian digunakan yaitu (1) normal atau hiperkinetik, (2) hipokinetik, (3) akinetik (tidak adanya penebalan miokard atau penebalan minimal), dan diskinetik (penipisan saat sistolik atau penipisan).
Intermitten PR Interval Changes Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 36, No. 4 Oktober - Desember 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i4.508

Abstract

Seorang anak perempuan usia 10 tahun dikonsulkan ke Divisi Aritmia dengan keluhan palpitasi berulang. Ekokardiografi menunjukkan anatomi dan fungsi jantung yang normal. Rekaman EKG diperlihatkan pada gambar 1.Takikardia QRS sempit dengan pola P-QRS-T yang menetap dapat merupakan suatu atrial atau sinus takikardia. Perhatikan bahwa gelombang P pada saat takikardia sama sekali berbeda dengan morfologi gelombang P saat irama sinus. Hal ini lebih menunjukkan suatu atrial takikardia daripada suatu irama sinus.Atrial takikardia bisa merupakan suatu fokal atau makroreentri. Suatu atrial makroreentri atau atrial flutter umumnya mempunyai panjang siklus antara 200–150 mdet, sedangkan pasien ini mempunyai panjang siklus (interval PP) sekitar 380 mdet sehingga suatu atrial takikardia yang fokal lebih memungkinkan. Di antara mekanisme atrial takikardia fokal dapat berupa otomatisasi, mikroreentri atau bahkan triggered activity. Perhatikan pola terminasi dan induksi

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