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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Biomedika Indonesian Journal of Cardiology Narra J Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute
Basuni Radi
Departemen Kardiologi Dan Kedokteran Vaskuler, Fakultas Kedokteran, Universitas Indonesia- Pusat Jantung Nasional Harapan Kita
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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PHASE II CARDIAC REHABILITATION PROGRAM IMPROVES FUNCTIONAL CAPACITY IN ATRIAL FIBRILLATION AND NON-ATRIAL FIBRILLATION PATIENTS AFTER MITRAL VALVE SURGERY Risalina Myrtha; Ignatius Faizal Yuwono; Andi Mahavira; Ade Meidian Ambari; Basuni Radi; Anwar Santoso; Budhi Setianto
Biomedika Vol 13, No 2 (2021): Biomedika Agustus 2021
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v13i2.13451

Abstract

ABSTRAKPenurunan kapasitas fungsional banyak ditemukan pada pasien fibrilasi atrium (FA) dengan berbagai kelainan jantung termasuk pasien yang menjalani operasi dan intervensi katup. Penelitian ini bertujuan untuk mengevaluasi pengaruh FA terhadap kapasitas fungsional pasien pasca operasi katup mitral yang menjalan program rehabilitasi jantung fase II. Penelitian ini merupakan penelitian potong lintang yang dilakukan pada pasien-pasien yang mengikuti program rehabilitasi jantung pasca operasi katup mitral di Pusat Jantung X Jakarta pada Januari hingga Desember 2013. Kapasitas fungsional pada pasien FA dibandingkan dengan pasien non-FA. Kapasitas fungsional diukur dengan menggunakan six-minute walking test distance (6MWD). Sejumlah 134 pasien yang diikutkan dalam penelitian ini, terdiri dari 61 pasien AF dan 73 pasien Non AF. am Hasil penelitian ini menyatakan bahwa program rehabilitasi jantung fase II meningkatkan kapasitas total pada kelompok AF dan Non AF, secara signifikan (p 0,001) pada kedua kelompok. Analisis regresi linear didapatkan bahwa 6MWD berkorelasi negatif dengan usia (p=0.001). Simpulan: Pasien-pasien pasca operasi katup mitral dengan FA mempunyai kapasitas fungsional awal yang lebih rendah, tetapi program rehabilitasi jantung dapat meningkatkan kapasitas fungsional dan peningkatan yang terjadi sebanding dengan kelompok dengan non-FA. Kata Kunci: Fibrilasi Atrium, 6MWD, Kapasitas Fungsional. ABSTRACTReduced functional capacity is commonly found in atrial fibrillation patients (AF) with various pathological cardiac disorders including patients undergoing valve surgery and intervention. This study aimed to investigate the effect of phase II cardiac rehabilitation program in functional capacity among AF and non-AF patients undergoing mitral valve surgery. We conducted a cross sectional research among AF and non-AF patients undergoing mitral valve surgery from January to December 2013 in X Cardiovascular Center Jakarta. We assessed functional capacity in both groups before and after phase II cardiac rehabilitation program. We used six minutes walking distance (6MWD) to evaluate the functional capacity. There were 134 subjects involved in this study.The AF group consisted of 61 subjects, and 73 subjects of Non-AF group. The results of this study were the phase II cardiac rehabilitation program enhanced the functional capacity of AF and Non AF groups, with significantly difference (p 0,001) on both groups. In linear regression analysis, age was negatively related with 6MWD (p=0.001). We concluded that phase II cardiac rehabilitation program could enhancefunctional capacityof AF and  non-AF group. Keywords: Atrial Fibrillation, 6MWD, Functional Capacity.
Pengaruh Latihan Fisik Dan Respon Molekuler Pembuluh Darah Arteri Dyana Sarvasti; Basuni Radi; Budhi Setianto; Andang H Joesoef
Jurnal Kardiologi Indonesia Vol. 32, No. 4 Oktober - Desember 2011
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v32i4.87

Abstract

Regular physical activity (exercise training, ET) has a strong positive link with cardiovascular health. The beneficial effects of ET on the endothelium arteries are believed to result from increased vascular shear stress during ET bouts. A number of mechanosensory mechanisms have been elucidated that may contribute to the effects of ET on vascular function. Exercise training also consistently improves the nitric oxide bioavailability, and the number of endothelial progenitor cells, and diminishes the level of inflammatory markers, namely pro inflammatory cytokines and C-reactive protein. This review summarizes current understanding of control of vascular adaptation by exercise and how these processes lead to improved cardiovascular health.
Disfungsi Autonom pada Pasien Penyakit Jantung Hipertensi Asimptomatik: Hasil evaluasi pemulihan laju jantung Yasmin Tadjoedin; Ismoyo Suni; Basuni Radi
Jurnal Kardiologi Indonesia Vol. 29, No. 3 September - Desember 2008
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v29i3.180

Abstract

Background.Imbalance of the autonomic nervous system has been known to have an important role in the pathophysiology of chronic heart failure (CHF). How early this imbalance occurs in CHF patients has not much been studied. We hypothesized that imbalance of the autonomic function evaluated with heart rate recovery (HRR) already occur in asymptomatic hypertensive patients with left ventricular hypertrophy (LVH) as subset of an early stage of CHF patients . Methods.Sixty two hypertensive patients (31 with LVH by echocardio-graphic criteria and 31 patients without LVH ) underwent treadmill exercise testing using the Bruce protocol and immediate supine on the recovery phase. Heart rate recovery was evaluated on minute 1 and 2 of the recov-ery phase and considered abnormal if = 18x/min in minute-1(HRR1) and = 42x/min in minute-2 (HRR2).Results.The mean HRR was significantly lower in hypertensive patients with LVH then the ones without LVH (19,48 ± 7,21 vs 26,45 ± 8,03) in minute-1, and (38,35 ± 11,19 vs 45,35 ± 9,97) in minute-2. An abnormal-ity in HRR1 percentage was found in 48.4% in patients with HHD and in 12.9% in patients without HHD. An inverse weak correlation (r = 0.329, p = 0.009) was found between LV mass index and HRR1.Conclusions.Abnormality of the HRR has already been found in hyper-tensive patients with LVH without signs or symptom of CHF suggesting an early occurrence of imbalance of the autonomic nervous system in early stage of CHF.
Profil Pemulihan Laju Jantung Orang Terlatih Adhantoro Rahadyan; Yasmin Tajoedin; Basuni Radi
Jurnal Kardiologi Indonesia Vol. 29, No. 1 Januari - April 2008
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v29i1.198

Abstract

Background. A faster recovery of heart rate after exercise has long been associated with higher level of fitness and prognosis. Recent studies have suggested that the rate in which heart rate recovers from exercise or heart rate recovery (HRR) is mediated by autonomic factors, particularly the rate at which vagal tone is reactivated. Several studies were published addressing the diagnostic and prognostic utility of HRR in patients with cardiac disease. This study was to obtain the value of HRR of well-trained men. Methods. It was an observational study that involved well-trained men who underwent medical examination included treadmill stress test in Saryanto Institute of Aerospace Medicine Jakarta.The value of the HRR was defined as the decrease of heart rate from peak exercise to second minute of recovery period. Results. One hundred and twenty eight subjects participated in the study. Thirty five were excluded due to incomplete data. The mean age was 22 ± 1.0 years. Mean heart rate recovery at 2 minutes was 57 ± 10 beat per minute. No different between those with resting heart rate of less than 60 and more than 60 (55 ± 10 vs 58±10 bpm; p:0.1) and amongs different fitness levels (Q1 vs Q4 : 56 ± 11 vs 59 ± 7 bpm, p:0.3)Conclusion. Heart rate recovery at 2 minutes in well-trained men was 57 ± 10 beat per minute.
Faktor-faktor Yang Mempengaruhi Heart Rate Recovery Pada Pasien Yang Menjalani Uji Latih Jantung Dengan Beban Henry A.P. Pakpahan; Andria Priyana; Adnil Basha; Basuni Radi
Jurnal Kardiologi Indonesia Vol. 28, No. 5 September 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i5.219

Abstract

Background. Heart rate recovery (HRR) has been recognized as an inde-pendent predictor of mortality.Objective.To identify factors that may affect HRR in patient with un-known coronary artery disease (CAD).Methods. This cross sectional study was performed in National Cardiac Center Harapan Kita. We reviewed the chart of patients with unknown CAD who underwent symptom-limited exercise stress testing for medical check up between January – December 2006. Factors that may influence HRR were recorded including current medications, peak exercise heart rate (HR), HR after 3-minute recovery, and the ischemic response to exer-cise. HRR was defined as the change in HR from peak exercise to 3-minute recovery. We further categorized patients to normal or abnormal HRR by using mean HRR as cut off value. All factors related to HRR and normal/abnormal categories were analyzed.Results. There were 188 patients aged 48 + 11 years. HRR significantly influenced by male sex (p=0.003), hypertension (p=0.028), â-blocker (p=0.03), calcium channel blocker (p=0.008), aspirin (p<0.001), and pro-voked ischemia (p=0.005). Using mean HRR (57x) as cut off, patients were classified as having normal (HRR <57x) or abnormal (HRR ? 57x). On fur-ther analysis, there was significant association between age (p=0.003), male sex (p=0.02), hypertension (p=0.02), use of â-blocker (p=0.026) and aspirin (p<0.005).Conclusion. In patients with unknown CAD who underwent symptom-limited exercise stress testing, HRR was influenced by age, male sex, hy-pertension, the presence of provoked ischemia, use of â-blocker, calcium channel blocker, and aspirin.
Penilaian Kualitas Hidup Pasien Pasca Bedah Pintas Koroner Yang Menjalani Rehabilitasi Fase III Kiki Abdurachim; Harmani Kalim; Basuni Radi
Jurnal Kardiologi Indonesia Vol. 28, No. 3 Mei 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i3.240

Abstract

Background. Coronary artery bypass graft surgery (CABG) is one of the management for coronary artery disease. Cardiovascular rehabilitation usually conducted for recovery and improved quality of life. Questionnaire was used to evaluate quality of life. One of the quality of life instrument most commonly used is Questionnaire SF-36. So far there isn’t any study to evaluate quality of life in patients post CABG who wish to follow rehabilitation program phase III in Indonesia.Methods and results.This is a cross sectional study conducted in the National Cardiovascular Centre (NCC) - Rehabilitation Division to patients post CABG in phase III rehabilitation program during 2004-2005. Subject was taken in consecutive sampling manner. Questionnaire SF-36 was handed directly or via mail. Validity and reliability test was done for the questionnaire form in Indonesia language. There were 112 patients, 34 patients did rehabilitation program in hospital and 78 were home-based. The characteristics between two groups were similar. Validity test using r product moment from Pearson to every questions in SF-36 showed r = 0,53-0.83 > 0,51 (r table) and Cronbach a= 0,855. SF-36 scoring was not significantly different among the two groups (in hospital rehab vs home-based rehab) and also control group (healthy). Conclusions. There were no difference in quality of life and aerobic ca-pacity in patients who performed rehabilitation program phase III in hospi-tal and home-based.
Farmakoterapi pada Upaya Berhenti Merokok Diyan Ekawati; Basuni Radi; Feni Fitriani Taufik
Jurnal Kardiologi Indonesia Vol. 36, No. 4 Oktober - Desember 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i4.505

Abstract

Nicotine dependence is a main role in tobacco dependence. Its physiological and psychological effect make smoker difficult to quit, making low success rate in smoking cessation. Combination of different method and continuity will increase smoking cessation success rate. Evidence shown that pharmacotherapy will increase success rate. Guideline’s for smoking cessation endorse physician to use first line pharmacotherapy, but it’s clinical application still limited. Physician should be aware about possibility for side effect. Some randomized controlled trial report major cardiovascular event in first line pharmacotherapy. Recent systematic review report no correlation between first line pharmacotherapy in smoking cessation and major cardiovascular event.
Era Jaminan Kesejahteraan Nasional: Tantangan dan Kesempatan untuk Standarisasi Pelayanan Kardiovaskular Basuni Radi
Jurnal Kardiologi Indonesia Vol. 37, No. 4 Oktober - Desember 2016
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v37i4.581

Abstract

Cerita dimulai dengan terbitnya Sistem Jaminan Sosial Nasional (SJSN) yang merupakan salah satu bentuk perlindungan sosial untuk menjamin seluruh rakyat agar dapat memenuhi kebutuhan dasar hidup yang layak.1 Sistem ini tentu saja ditunggu oleh berbagai pihak yang mengharapkan peningkatan kesejahteraan masyarakat dengan jaminan sosial dari negara.
Kembali Beraktivitas Seksual Pasca Bedah Pintas Arteri Koroner Dwita R Desandri R Desandri; AH Raynaldo; Basuni Radi; Siti F Supari F Supari; Budhi Setianto; Dede Kusmana
Jurnal Kardiologi Indonesia Vol. 37, No. 4 Oktober - Desember 2016
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v37i4.584

Abstract

Surgical coronary revascularization can affect the quality of life and psychosocial functions, including the return of sexual activity. A 43-year-old male patient underwent four graft coronary artery bypass (CABG) surgery at National Cardiovascular Center Harapan Kita. The second phase of rehabilitation results showed patient’s functional capacity is 9.75 METs and ischemic negative response. Before surgery, patient often experienced chest pain during intercourse. The patient must consume sublingual isosorbide dinitrate (ISDN). Currently the patient is no longer feel chest pain during intercourse, but he was still afraid to do intercourse and reduce the activity frequency.Return to sexual activity after undergoing CABG surgery is a common concern. Cardiac rehabilitation program and sexual counseling can help patients to return to their sexual function and activity.
Improvement of exercise capacity after early phase II cardiac rehabilitation in patients who undergo rheumatic mitral valve surgery Ade Meidian Ambari; Budhi Setianto; Anwar Santoso; Basuni Radi; Bambang Dwiputra; Eliana Susilowati; Fadila Tulrahmi; Pieter A Doevendans; Maarten Jan Cramer
Jurnal Kardiologi Indonesia Vol 41 No 3 (2020): Indonesian Journal of Cardiology: July - September 2020
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1038

Abstract

Background: Rheumatic heart disease still become a major concern in developing countries. Recent studies showed the benefits of early phase II cardiac rehabilitation (CR) on improving the exercise capacity but the evidence in patients after rheumatic mitral valve surgery due to rheumatic heart disease is limited. This study aims to investigate the effects of early phase II CR program on increasing exercise capacity in the rheumatic mitral valve surgery patients. Methods: This is a cohort retrospective study. A review of medical records identified 254 patients who underwent early phase II CR after rheumatic mitral valve surgery between July 2009 – June 2019. Effects of CR was assessed by 6 Minutes Walking Distance (6MWD) pre and post early phase II CR and peak oxygen uptake (VO2 peak) calculated by Cahallin formula. In this study, we observed and analyzed the increasing of 6MWD and VO2 peak. Results: Our findings showed that 6MWD and VO2 peak increased significantly in these patients after early phase II CR program (p = 0.001). Mean of 6MWD increased from 316.3 ± 71.7 meters to 378.6 ± 60.3 meters and VO2 peak increased from 7.7 ±2.4 mL/kg/min to 8.9 ± 2.2 mL/kg/min. The mean difference of 6MWD was 62.3 meters and VO2 peak was 1.2 mL/kg/min. There was a strong correlation between VO2 peak and 6MWD (r = 71%; R2 = 51%; p = 0.001). Conclusion: Early phase II CR in patients with Rheumatic Mitral Stenosis after mitral valve surgery improved the exercise capacity. Based on 6MWD, we can predict the value of VO2 peak patients with rheumatic mitral stenosis surgery patients. Keywords: Cardiac rehabilitation, rheumatic mitral stenosis, 6MWD, VO2 peak
Co-Authors Ade Meidian Ambari Ade Meidian Ambari Ade Meidian Ambari Ade Meidian Ambari Adhantoro Rahadyan Adnil Basha AH Raynaldo Ambari, Ade Meidian Amiliana M Soesanto Amiliana Mardiani Soesanto Amir Aziz AlKatiri Andang H Joesoef Andi Mahavira Andria Priyana Anggoro Budi Hartopo Anwar Santoso Anwar Santoso Anwar Santoso Aria Kekalih Ario Suryo Kuncoro Bambang Budi Siswanto Bambang Dwiputra Bambang Dwiputra Bima Suryaatmaja Budhi Setianto Budhi Setianto Budhi Setianto Dede Kusmana Desandri, Dwita Rian Diyan Ekawati Dwiputra, Bambang Dwita R Desandri R Desandri Dyana Sarvasti Eliana Susilowati Fadila Tulrahmi Harahap, Alida R. Harahap, Alida Rosita Harmani Kalim Henry A.P. Pakpahan Ignatius Faizal Yuwono Irsad Andi Arso Ismoyo Suni Katsukawa, Hajime Kiki Abdurachim Maarten Jan Cramer Pieter A Doevendans Risalina Myrtha Siti F Supari F Supari Solly Aryza Surya marthias Tambunan, Tresia Fransiska Ulianna Tambunan, Tresia FU. Taufik, Feni Fitriani Teuku Heriansyah, Teuku Triangto, Kevin Yasmin Tadjoedin Yasmin Tajoedin