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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
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Articles 16 Documents
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Search results for , issue "Volume 7 No. 3 July 2019" : 16 Documents clear
Accuracy of Fetal Weight Estimation Using Hadlock II Formula: Keakuratan Taksiran Berat Janin Menggunakan Rumus Hadlock II Dwi P. Anjarwati; Yudhistya N.I. Ksyatria; Widardo Widardo
Indonesian Journal of Obstetrics and Gynecology Volume 7 No. 3 July 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (56.549 KB) | DOI: 10.32771/inajog.v7i3.556

Abstract

abstract Objective: to investigate the accuracy of estimated fetal weight using Hadlock II formula in RSUD Dr Moewardi. Methods: This cross-sectional study was conducted at RSUD Dr Moewardi in June 2017. Subjects were women who gave birth at RSUD Dr Moewardi from August 2014 to March 2017. The method of collecting data by quoting the medical record as required. Data analysis was done by using linear regression statistic test. Result: By distribution, the number of samples that, according to the standard, is 81.67 %. With the value of R = 0.706 which means that the relationship between two research variables are strong and the value of R Square = 0.499 which means that estimated fetal weight using Hadlock II formula has contribution 49.9 % on fetal birth weight and 50.1 % others by other factors. Conclusion: Fetal weight estimation using Hadlock II formula in RSUD Dr Moewardi has low accuracy. Operator skills training is required to improve the accuracy of estimated fetal weight. Keywords: fetal birth weight, fetal weight estimation, Hadlock II abstrak Tujuan : Mengetahui keakuratan taksiran berat janin menggunakan rumus Hadlock II di RSUD Dr Moewardi. Metode : Penelitian ini adalah penelitian observasional analitik. Penelitian ini dilaksanakan di RSUD Dr Moewardi pada Juni 2017. Subjek penelitian ini adalah data rekam medis dari ibu hamil yang mengalami partus di RSUD Dr Moewardi pada Agustus 2014 – Maret 2017. Metode pengumpulan data dengan mengutip data rekam medis pasien sesuai ketentuan. Analisis data dilakukan dengan uji statistik regresi linier. Hasil : Secara distribusi, jumlah sampel yang memenuhi standar yaitu 81,67 %. Dengan nilai R = 0,706 yang artinya bahwa hubungan kedua variabel penelitian ada dalam kategori kuat dan nilai R Square = 0,499 yang berarti taksiran berat janin menggunakan rumus Hadlock II memiliki pengaruh kontribusi sebesar 49,9% terhadap berat bayi lahir sedangkan 50.1 % lainnya dipengaruhi oleh faktor lain. Kesimpulan : Taksiran berat janin menggunakan rumus Hadlock II di RSUD Dr Moewardi kurang akurat. Perlu dilakukan pelatihan ketrampilan operator sehingga diharapkan dapat meningkatkan keakuratan taksiran berat janin. Kata kunci: berat bayi lahir , Hadlock II, , taksiran berat janin
The risk of sensorineural hearing impairment in preeclampsia: Risiko Gangguan Pendengaran Sensorineural pada Pasien Preeklamsia Achmad Taufan; Nuswil Bernolian; Yusuf Efendi; Alba G.E. Bahar
Indonesian Journal of Obstetrics and Gynecology Volume 7 No. 3 July 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (56.948 KB) | DOI: 10.32771/inajog.v7i3.585

Abstract

Abstract Objective: To determine the risk of sensorineural hearing impairment in preeclampsia patients and to in Obstetric and Gynecology Department in Dr. Mohammad Hoesin Hospital Palembang. Method: An analytic observational case-control study was held in Dr. Mohammad Hoesin Hospital Palembang from January 1st to December 31st 2016. Subjects were obtained through consecutive sampling. Hypothetical tests used were unpaired t-test, Chi-square test and Fisher test for expected deviation standard <5, significance determined based on p-value if p<0.05. Data progressing and analysis were done using SPSS version 17.0 for windows. Results: Characteristics distribution of the subjects were overall homogenous. With the Chi-square test, no significant difference was found in hearing function examination with OAE and tympanometry in both groups (p>0.05). From unpaired t-test, there was no significant difference between mean Air Conducting (AC) and Bone Conducting (BC) of the right ear in severe preeclampsia group and healthy pregnancy group (p=0.340), as well as mean AC and BC of the left ear in severe preeclampsia group and healthy pregnancy group (p=0.059). Based on the Fisher's Exact test, no significant relation was found between severe preeclampsia and sensorineural hearing impairment (p=0.999). Conclusion:There was no significant relation between severe preeclampsia and sensorineural hearing impairment in Obstetric and Gynecology Department in Dr. Mohammad Hoesin Palembang. Keywords: otoacoustic emission, preeclampsia, sensorineural hearing impairment. Abstrak Tujuan: Mengetahui risiko gangguan pendengaran sensorineural pada pasien dengan preeklamsia di Departemen Obstetri dan Ginekologi RSUP Mohammad Hoesin Palembang. Metode: Penelitian analitik observasional dengan disain kasus kontrol pada wanita hamil di RSMH sejak 1 Januari – 31 Desember 2016. Subjek dipilih secara consecutive sampling. Analisis dengan uji t tak berpasangan, Chi-square, dan uji Fisher untuk ekspektasi sd<5, kemaknaan ditentukan berdasarkan (p) jika p<0.05. Proses mengolah dan analisis data ini dilakukan menggunakan SPSS 17.0 for windows. Hasil: Distribusi karakteristik umum subjek secara keseluruhan adalah homogen. Berdasarkan uji Chi Square, tidak didapatkan perbedaan bermakna hasil pemeriksaan fungsi pendengaran dengan OAE dan Timpanometri pada kedua kelompok (p>0,05). Dengan uji T tidak berpasangan, tidak didapatkan perbedaan bermakna rerata Air Conducting (AC) dan Bone Conducting (BC) telinga kanan kelompok PEB dan kelompok hamil normal (p=0,340), begitu juga dengan rerata Air Conducting (AC) dan Bone Conducting (BC) telinga kiri kelompok PEB dan kelompok hamil normal (p=0,059). Berdasarkan uji statistik Fisher, tidak didapatkan hubungan bermakna antara preeklamsia berat dengan gangguan pendengaran sensorineural (p=0,999). Simpulan:Tidak terdapat hubungan yang bermakna antara preeklamsia berat dengan gangguan pendengaran sensorineural berdasarkan pemeriksaan audiometri di Departemen Obstetrik dan Ginekologi RSUP Dr. Mohammad Hoesin Palembang. Kata kunci: gangguan pendengaran sensorineural, otoacoustic emission, preeklamsia
Factors Affecting the Drop Out Rate of Family Planning Intrauterine Device: Hubungan Faktor-Faktor yang Mempengaruhi Drop Out Peserta Akseptor Keluarga Berencana IUD dengan Tingkat Kepatuhan Mariana Afiati; Azhari Azhari; Firmansyah Basir; Theodorus Theodorus
Indonesian Journal of Obstetrics and Gynecology Volume 7 No. 3 July 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (61.344 KB) | DOI: 10.32771/inajog.v7i3.606

Abstract

Abstract Objective: to assess the association between risk factors related to IUD acceptors' compliance at RSMH Palembang. Methods: This cross-sectional study was conducted in the Department of Obstetrics and Gynecology Dr. Mohammad Hoesin Hospital/Faculty of Medicine Sriwijaya University Palembang since May - December 2017. Subjects were women who use IUD contraceptives in the Department of Obstetrics and Gynecology Dr.MohammadHoesin Hospital Palembang and meet our inclusion and exclusion criteria. Medical counselling, knowledge, and side effects were assessed using a questionnaire. Data were analyzed by Chi-square test using SPSS software version 17. Results: There was a significant relationship between side effects and compliance of IUD use. There was no significant correlation between knowledge and medical counselling with compliance of IUD. Conclusions: Side effects associated with compliance of IUD. Keywords:compliance, contraception, IUD Abstrak Tujuan: mengetahui hubungan faktor-faktor resiko yang bermakna dalam mempengaruhi kepatuhan peserta akseptor IUD di RSMH Palembang. Metode: Penelitian potong lintang ini dilakukan di Departemen Obstetri dan Ginekologi Rumah Sakit Dr. Mohammad Hoesin/Fakultas Kedokteran Universitas Sriwijaya Palembang sejak Mei – Desember 2017. Sampel penelitian ini adalah perempuan yang menggunakan kontrasepsi IUD di Departemen Obstetri dan Ginekologi Rumah Sakit Dr. Mohammad Hoesin/Fakultas Kedokteran Universitas Sriwijaya Palembang dan memenuhi kriteria inklusi dan eksklusi. Konseling medik, pengetahuan, dan efek samping dinilai dengan menggunakan kuesioner. Data dianalisis dengan uji Chi square menggunakan SPSS versi 17. Hasil: Ada hubungan bermakna antara efek samping IUD dengan kepatuhan pemakaian IUD. Tidak ditemukan hubungan bermakna antara tingkat pengetahuan dan konseling medic dengan kepatuhan akseptor IUD. Kesimpulan: Efek samping IUD mempengaruhi kepatuhan pemakaian IUD. Kata kunci: IUD, kontrasepsi, kepatuhan.
Knowlegde, Atittude and Behaviour of Midwifes torwards Emergency Contraception: Tingkat Pengetahuan, Sikap dan Perilaku Bidan terhadap Kontrasepsi Darurat Eka R. Gunardi; Leonanta M. Ginting
Indonesian Journal of Obstetrics and Gynecology Volume 7 No. 3 July 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (53.315 KB) | DOI: 10.32771/inajog.v7i3.641

Abstract

Abstract Objective: To investigatethe level of knowledge, attitude, and behaviour of midwives to emergency contraception in Indonesia. Methods: This study used a cross-sectional design. Subjects were midwives who worked in the District CipondohTangerang, Banten, Indonesia until the number of subjects is met at least 100 people. The data were collected by using written questionnaires made by researchers based on previous studies with similar themes. The data obtained will be reported descriptively for categorical variables. The analysis results are presented in the form of sum (n) and percentage (%) (proportion). Results: Of the 100 respondents who answered the questionnaire, 83% of the midwives had a good knowledge of the condition. Good midwife attitude toward EC in public health care and private practices were 84.62% and 85.06%, respectively. Accordingly, the good behaviour shown by midwives in public health care and private practice is 100% and 94.25%. However, from the question qualitatively the level of knowledge, attitude and behaviour of midwives is still classified as less. Conclusion: The level of knowledge, attitude and behaviour of midwives towards emergency contraception is said to be lacking. Training on EC on midwives is still needed for practical use in the community. Keywords: emergency contraception, midwife, unwanted pregnancy, uterine contraception Abstrak Tujuan:Mengetahui tingkat pengetahuan, sikap, dan perilaku bidan terhadap kondar di Indonesia. Metode:Penelitian ini menggunakan desain potong lintang dengan pengambilan sampel berturut-turut. Peneliti mengambil semua subjek yaitu bidan yang bekerja di wilayah Kecamatan Cipondoh Kabupaten Tangerang sampai jumlah subjek minimal terpenuhi sebanyak 100orang. Pengambilan data dilakukan dengan menggunakan kuesioner tertulis yang dibuat oleh peneliti berdasarkan penelitian-penelitian terdahulu dengan tema serupa. Data yang diperoleh akan dilaporkan secara deskriptif untuk variable kategorik. Hasil analisis disajikan dalam bentuk jumlah (n) dan persentase (%) (proporsi). Hasil: Dari 100 responden, 83% bidan mempunyai pengetahuan yang baik terhadap kontraspsi darurat. Sikap bidan yang baik terhadap kondar di puskesmas dan di praktik swasta adalah 84,62% dan 85,06%, berturut-turut. Sejalan dengan itu, perilaku yang baik ditunjukkan oleh bidan di puskesmas dan di praktik swasta adalah sebesar 100% dan 94,25%. Namun dari pertanyaan secara kualitatif tingkat pengetahuan , sikap dan prilaku bidan masih tergolong kurang. Kesimpulan:Tingkat pengetahuan, sikap dan perilaku bidan terhadap kontrasepsi darurat dikatakan masih kurang. Masih dibutuhkan pelatihan tentang kondar pada bidan agar penggunaannya efektif di masyarakat. Kata kunci: alat kontrasepsi dalam rahim, bidan, kehamilan tidak diinginkan, kontrasepsi darurat.
Old Perineal Rupture - From Diagnosis to Reparation: Ruptur Perineum Lama: Diagnosis sampai Perbaikan Budi I. Santoso; Nadir Chan; Leonardo Leonardo
Indonesian Journal of Obstetrics and Gynecology Volume 7 No. 3 July 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (62.549 KB) | DOI: 10.32771/inajog.v7i3.664

Abstract

Abstract Objective: To describe and discuss the technique to diagnose, preparing the reparation and postoperative management in old perineal rupture case.Methods: A 28-year-old primipara woman was referred to YPK Mandiri Hospital after having incontinence to flatus, to urinate and passive soiling. Three months before admission, she had her first child through vaginal delivery.Discussion: She was diagnosed with a third-degree obstetric anal sphincter injury (OASIS). Rectal examination with digital palpation (pill-rolling motion) and ultrasound examination, revealed a distinct gap anteriorly (10 – 2 o'clock). End to end technique was preferred to repair the defect.Conclusion: A good understanding of perineal and anal sphincter anatomy is essential to diagnose OASIS. The aim of reconstructive surgery is to restore the continuity of both the external and internal anal sphincters. Ideally, the repair should be performed as soon as possible after the injury.Keywords:obstetric anal sphincter injuries, OASIS, third-degree tear, perineum, perineal trauma. Abstrak Tujuan:Untuk mendeskripsikan dan diskusi tentang tehnik dalam mendiagnosa, mempersiapkan operasi reparasi dan manajemen pasca operasi pada kasus rupture perineum lama.Metode:Sebuah laporan kasus yang diambil dari pasien perrempuan 28 tahun primipara yang dirujuk ke RS YPK Mandiri setelah mengeluhkan inkontinensia flatus, urin, dan keluarnya feses tanpa disadari. Tiga bulan sebelumnya, pasien melahirkan anak pertama melalui persalinan pervaginam.Diskusi: Diagnosa pasien adalah cedera sfingter ani obstetrik derajat tiga. Pemeriksaan rektal dengan palpasi digital (gerakan pill-rolling) dan pemeriksaan ultrasonografi, memperlihatkan adanya penipisan di daerah anterior (arah jam 10 – 2). Teknik end to end dipilih untuk memperbaiki defek.Kesimpulan:Pengetahuan yang baik mengenai anatomi perineum dan sfingter ani penting untuk mendiagnosis OASIS. Tujuan utama dari operasi rekonstruksi adalah untuk memperbaiki kontinuitas dari sfingter ani eksternal dan internal. Idealnya, reparasi dilakukan secepat mungkin setelah terjadinya cedera. Kata kunci: cedera sfingter ani obstetrik, OASIS, perineum, trauma perineum, robekan derajat tiga
Pap Smear Cytology Results in Patients Under Visual Inspection of Acetic Acid (VIA) at Primary Health Care: Hasil Sitologi Pap Smear pada Pasien di Bawah Inspeksi Visual Asam Asetat (IVA) di Pusat Perawatan Kesehatan Utama Ivan M. Sondakh; Bismarck J. Laihad; Eddy Suparman
Indonesian Journal of Obstetrics and Gynecology Volume 7 No. 3 July 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (54.305 KB) | DOI: 10.32771/inajog.v7i3.834

Abstract

Abstract Objective: we compared the results of Pap Smear and VIA in Primary Healthcare Centres (PHCs). Methods: This was a descriptive study that investigated Pap smear cytology results in patients who underwent visual inspection of acetic acid in PHC for early detection of cervical cancer. This research was done in three PHCs (Tikala Baru, Tuminting and Paniki), which appointed by Manado Health Department as they have certified general practitioner, midwives, and nurse for VIA examination. The Pap smear examination was performed by researchers and VIA performed by certified PHC VIA Team using tools, equipment, available at the PHCs without intervention. Results: Of 55 subjects, 15 and 40 subjects were VIA positive and negative, respectively. Fifteen samples with positive VIA there were only three subjects with dysplasia (LSIL) results in Pap smear, and 40 samples with VIA negative there were two samples with dysplasia (LSIL) results in Pap smear. Conclusion: The result of VIA examination in primary health care with VIA positive was only 20% had dysplasia (LSIL) on pap smears, and negative VIA sample was 5% with dysplasia (LSIL) on Pap smear. Keywords:cervical cancer, pap smear, VIA. Abstrak Tujuan: membandingkan hasil pemeriksaan gambaran sitologi Pap Smear dengan hasilpemeriksaan IVA di Puskesmas. Metode:Penelitian ini merupakan penelitian deskriptif untuk mengetahui hasil sitologi Pap Smear pada pasien yang telah dilakukan pemeriksaan inspeksi visual asam asetat di fasilitas kesehatan tingkat I untuk deteksi dini kanker serviks. Penelitian ini dilakukan di tiga Puskesmas (Puskesmas Tikala Baru, Tuminting, dan Paniki) yang telah diberikan pelatihan IVA yang ditunjuk oleh Dinas Kesehatan Kota Manado. Pemeriksaan Pap Smear dilakukan oleh penelitidan IVA dilakukan oleh petugas kesehatan tingkat I dengan menggunakan alat, perlengkapan, yang tersedia di Puskesmas tanpa intervensi. Hasil :Dari 55 subyek, didapatkan 15 subyek dengan IVA positif, dan 40 subyek dengan IVA negatif. Dari 15 subyek dengan IVA positif hanya terdapat 3 orang diantara dengan hasil displasia pada Pap Smear, dan 40 subyek dengan IVA negatif terdapat 2 orang dengan hasil displasia pada Pap Smear. Kesimpulan: Hasil pemeriksaan IVA di fasilitas kesehatan tingkat I dengan IVA positif hanya 20% memliki gambaran displasia (LSIL) pada hasil Pap smear dan sampel dengan IVA negative terdapat 5% dengan gambaran displasia (LSIL) pada hasil Pap Smear. Kata Kunci: IVA, kanker serviks, pap smear.
Diagnostic Value of Transvaginal Ultrasonography to Determined Degree of Myometrium Invasion in Endometrial Cancer: Nilai Diagnostik Ultrasonografi Transvaginal dalam Menilai Kedalaman Invasi ke Miometrium pada Kanker Endometrium Kartiwa H. Nuryanto; Selly Fransiska
Indonesian Journal of Obstetrics and Gynecology Volume 7 No. 3 July 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (64.839 KB) | DOI: 10.32771/inajog.v7i3.836

Abstract

Abstract Objectives: To show transvaginal ultrasound accuracy in determining the degree of myometrial invasion of endometrial cancer within five years in RSCM. Also, to know histopathology characteristics of endometrial cancer according to cell type, degree of invasion, and degree of differentiation of endometrial cancer, within the last five years in RSCM. Methods: This study is a cross-sectional study with a sample of 82 subjects in January 2011 – December 2016 at RSCM. The data were collected by total sampling from cancer registry oncology and gynaecology division of Obstetrics and Gynecology FKUI-RSCM. Results: Transvaginal USG diagnostic test in detection invasion has sensitivity, specificity, PPV, and NPV as 78.79%, 50%, 86.67%, 36.36% respectively. For determine degree of myometrial invasion it has sensitivity, specificity, PPV, and NPV as 81.40%, 76.92%, 79.55%, and 78.90% respectively. Conclusions: Transvaginal ultrasound has better accuracy in determining the degree of invasion compared to detecting myometrial invasion in endometrial cancer. In determining the degree of invasion, its sensitivity and specificity are 81.4% and 76.92%. For detecting any invasion its sensitivity and specificity was only 79.41% and 57.14%. Our study showed that transvaginal ultrasound was an efficient diagnostic tool fo determine further treatment and prognosis in endometrial cancer Keywords: accuracy test, HPV DNA, liquid-based cytology, pre-cervical cancer lesion. Abstrak Tujuan : Mengetahui akurasi USG transvaginal dalam menilai invasi miometrium pada kanker endometrium dalam 5 tahun terakhir di RSCM. Serta karakteristik histopatologi berdasarkan tipe, invasi, dan derajat diferensiasi kanker endometrium dalam 5 tahun terakhir di RSCM Metode :Penelitian potong lintang dengan jumlah sampel 82 subjek pada Jan 2011 – Des 2016 di RSCM. Data dikumpulkan secara total sampling dari registrasi kanker divisi Onkologi Ginekologi FKUI RSCM dan dilakukan uji diagnostik Hasil: Uji diagnostik USG transvaginal menilai ada tidaknya invasi memiliki sensitivitas, spesifisitas, NPP, NPN sebesar 78,79%, 50%, 86,67%, 36,36%. Sedangkan hasil uji diagnostik usg transvaginal dalam menilai derajat invasi memiliki sensitivitas, spesifisitas, NPP, NPN sebesar 81.40%, 76.92%, 79.55%, dan 78.90% Kesimpulan :USG transvaginal dalam menilai derajat invasi lebih baik dibanding menentukan ada tidaknya invasi. Sensitivitas, spesifisitasnya 81,4-% dan 76,92% dibanding 79,41% dan 57,14%. Dalam hal ini USG transvaginal dapat digunakan sebagai alat bantu diagnostik efisien dalam menentukan tata laksana dan prognosis kanker endometrium Kata kunci : kanker endometrium, kedalaman invasi, uji diagnostik, USG transvaginal.
Microscopic Examination of Urine Samples as the Early Detection of Asymptomatic Urinary Tract Infection in Pregnant Women: A Cross-Sectional Study: Uji Mikroskopik Spesimen Urin sebagai Deteksi Dini Infeksi Saluran Kemih tidak Bergejala pada Perempuan Hamil: Sebuah Studi Potong Lintang Yeva Rosana; Dwiana Ocviyanti; Rahmah Amran
Indonesian Journal of Obstetrics and Gynecology Volume 7 No. 3 July 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (71.937 KB) | DOI: 10.32771/inajog.v7i3.899

Abstract

Abstract Objectives:To investigate the role of microscopic examination of urine sample in supporting early diagnosis of asymptomatic urinary tract infection (UTI) in pregnant women. To compare correspondence between microscopic examination and urine culture result as a gold standard diagnostic modality to support the diagnosis of UTIs and as an evidence-based to start empirical therapy. Methods: Microscopic analysis was conducted in 74 centrifuged and non-centrifuged urine samples from 317 pregnant who came to six healthcare centres in Jakarta, which showed a positive result of nitrite examination. The results of the microscopic examination of bacteriuria and leukocyturia were compared with a urine culture. Results: Sensitivity of centrifuged bacteriuria was the highest among the other microscopic parameters, which was 74% with the p-value of 0.009. Combination of bacteriuria and leukocyturia≥3/HPF dan≥5/HPF have increased the specificity with the value of 91.5% and 93.6% in non-centrifuged urine. Conclusion: This result showed that the best method of microscopic examination for early diagnosis of asymptomatic urinary tract infection in pregnant women is the detection of bacteriuria in centrifuged urine. Combination of bacteriuriaandleukocyturiatest, as well as leukocyturia≥3/HPF and≥5/HPF, can be used to rule out the diagnosis of UTI at an early stage. Keywords: asymptomatic urinary tract infection, bacteriuria, leukocyturia,microscopic examination, urine culture. Abstrak Tujuan: Mengetahui peran pemeriksaan mikroskopis sampel urin dalam mendukung diagnosis dini infeksi saluran kemih asimptomatik (ISK) pada perempuan hamil. Membandingkan kesesuaian antara pemeriksaan mikroskopis dan hasil kultur urin sebagai modalitas diagnostik standar emas untuk mendukung diagnosis ISK dan sebagai dasar bukti untuk memulai terapi empiris. Metode: Penelitian uji mikroskopik dilakukan pada 74 sampel urin disentrifugasi dan tidak sentrifugasi, dari 317 sampel urin perempuan hamil yang berobat ke-enam puskesmas di Jakarta dengan uji nitritpositif. Hasil uji mikroskopik bakteri uria dan leukosit uria dibandingkan dengan hasil kultururin. Hasil: Sensitivitas bakteriuria yang disentrifugasi menunjukan hasil yang paling baik dibandingkan dengan parameter uji mikroskopik lain, yaitu 74% dengan nilai p yang bermakna sebesar 0,009. Kombinasi bakteri uria dan leukosituria ≥3/LPB dan ≥5/LPB dapat meningkatkan spesifisitas uji dengan nilai 91,5% dan 93,6% pada urin yang tidak disentrifugasi. Kesimpulan: Hasil menunjukkan bahwa bakteri uria pada urin yang disentrifugasi, merupakan metode yang paling baik untuk membantu diagnosis dini ISK tidak bergejala pada perempuan hamil. Uji kombinasi bakteri uria dan leukosituria, serta uji leukosituria ≥3/LPB dan ≥5/LPB dapat dimanfaatkan untuk membantu secara dini menyingkirkan orang yang tidak mengalami ISK. Kata kunci: bakteriuria, infeksi saluran kemih tidak bergejala, kultur urin,leukosituria, uji mikroskopik
The Accuracy of Modified Risk Malignancy Index (RMI) in Predicting Malignancy of Epithelial Type Ovarian Cancer: Akurasi Modifikasi Risk of Malignancy Index dalam Memprediksi Keganasan Tumor Ovarium Tipe Epitel Esfi Triana; Defrin Defrin; Joserizal Serudji; Adriswan Adriswan
Indonesian Journal of Obstetrics and Gynecology Volume 7 No. 3 July 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (70.75 KB) | DOI: 10.32771/inajog.v7i3.900

Abstract

Abstract Objective:To investigate the accuracy of modified Risk of Malignancy Index (RMI) in predicting malignancy of epithelial type ovarian tumour. Method: This research was comparative research using cross-sectional study design, which compared RMI modification and RMI method in predicting malignancy of epithelial type ovarian tumour. The sampling technique was consecutive sampling. This research was conducted on October 2017 until samples were fulfilled in Obstetrics and Gynecology Division of RSUP Dr. M. Djamil and Laboratory of RSUP Dr. M Djamil in Padang. Chi-square test was used to compare specificity, sensitivity, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (PLR), negative likelihood ratio (NLR, and accuracy of RMI modification and RMI with 95% CI (p≤0,05). Results: A total of 61 subjects were recruited in this study. Sensitivity, specificity, PPV, NPV, PLR, NLR, and accuracy RMI modification scoring was 90.5%, 82.5%, 73.1%, 94.3%, 5.1, 0.1, dan 85.2%. Sensitivity, specificity, PPV, NPV, PLR, NLR, and accuracy RMI scoring was 66.7%, 70%, 53.8%, 80%, 2.2, 0.4, and 70% Conclusions:Modified RMI scoring method was more accurate in predicting the malignancy of ovarian type epithelial tumours than RMI. Keywords: CA125, malignancy, ovarian tumor,pelvic mass, RMI, Abstrak Tujuan: Mengetahui akurasi Risk of Malignancy Index (RMI) dalam prediksi keganasan tumor ovarium tipe epitel. Metode: Penelitian ini merupakan penelitian komparatif dengan desain penelitian potong lintang yang membandingkan metode RMI modifikasi dan RMI dalam prediksi keganasan tumor ovarium tipe epitel. Jumlah sampel sebanyak 61 orang. Teknik pengambilan sampel berurutan. Penelitian di mulai pada bulan Oktober 2017 hingga jumlah sampel terpenuhi di Departemen Obstetri dan Ginekologi RSUP Dr. M Djamil dan Laboratorium RSUP Dr. M Djamil Padang. Untuk membandingkan spesifisitas, sensitivitas, nilai duga positif (NDP), nilai duga negatif (NDN), rasio kemungkinan positif (RKP), rasio kemungkinan negatif (RKN), dan akurasi RMI modifikasi dan RMI digunakan uji chi-square dengan 99% CI (p≤0,01). Hasil: Sensitivitas, spesifisitas, NDP, NDN, RKP, RKN, dan akurasi skoring RMI modifikasi adalah 90,5%, 82,5%, 73,1%, 94,3%, 5,1, 0,1, dan 85,2%. Sensitivitas, spesifisitas, NDP, NDN, RKP, RKN, dan akurasi skoring RMI adalah 66,7%, 70%, 53,8%, 80%, 2,2, 0,4, dan 70%. Kesimpulan: Metode skoring RMI modifikasi lebih akurat dalam memprediksi keganasan tumor ovarium tipe epitel dibandingkan RMI. Kata kunci: CA125, keganasan, massapelvik, RMI, tumor ovarium
Neurofibrillary Pathology in the Infundibular Nucleus in Relation to Age and Abnormal Hormone Levels: Patologi Neurofibrilar pada Nukleus Infundibularis Terkait Usia dan Kadar Hormon Abnormal Andon Hestiantoro; Dick F. Swaab
Indonesian Journal of Obstetrics and Gynecology Volume 7 No. 3 July 2019
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (214.826 KB) | DOI: 10.32771/inajog.v7i3.962

Abstract

Abstract Objective: to determine whether the decline of testosterone during ageing would make this nucleus more vulnerable for NF changes (i.e. hyperphosphorylated-tau) in men, or that the decline of estrogens in the postmenopausal period would protect the infundibular nucleus in women. Methods: We investigated the infundibular nucleus in postmortem subjects. Brain materials obtained from 29 subjects in the Netherlands Brain Bank were further classified as control subjects and subjects with abnormal hormone conditions. Procedures consisted of tissue collection, immunochemical staining, and analysis of the staining intensity. Results then were collected and concluded using observational methods. Results: Elderly male subjects with low testosterone conditions showed more severe NF changes in the infundibular nucleus than postmenopausal women. The occurrence of NF changes in elderly subjects was generally accompanied by the presence of basket-like nerve terminals staining for ERβ. Conclusion: The sex difference in NF changes in the infundibular nucleus in the elderly is due to hyperphosphorylated-tau induction in low testosterone and ageing condition in men, while in postmenopausal women the declining estrogen levels seem to protect against NF changes in this brain area. Keywords: ageing, estrogen, hyperphosphorylated-tau, infundibular nucleus, testosterone Abstrak Tujuan: untuk menentukan apakah penurunan level testosteron selama proses penuaan menyebabkan nukleus infundibularis menjadi lebih rentan terhadap perubahan neurofibrilar (NF) (misalnya hyperphosphorylated-tau) pada laki-laki atau apakah penurunan level estrogen selama masa pasca-menopause memiliki efek protektif terhadap nukleus infundibular pada perempuan. Metode: Peneliti memeriksa nukleus infundibular pada subjekpost-mortem. Materi berupa jaringan otak dari 29 subjek dari Netherlands Brain Bank lebih lanjut diklasifikasikan sebagai subjek kontrol dan subjek dengan kondisi hormon abnormal. Prosedur terdiri dari pengumpulan jaringan, pewarnaan dengan teknik imunohistokimia, dan analisis dari intensitas pewarnaan. Hasil yang didapat kemudian dikumpulkan dan disimpulkan sesuai dengan metode observasional. Hasil: Subjek laki-laki lanjut usia dengan testosteron rendah menunjukkan perubahan NF yang lebih buruk pada nukleus infundibular dibandingkan dengan wanita postmenopause. Kejadian perubahan NF pada subjek lanjut usia secara umum diikuti oleh munculnya pewarnaan pada ujung saraf berbentuk basket-like yang positif untuk Erβ. Kesimpulan:Perbedaan jenis kelamin terkait perubahan NF pada nukleus infundibular pada subjek lanjut usia terjadi akibat induksi hiperfosforilasi taupada kondisi testosteron yang rendah yang dikombinasi oleh proses penuaan pada pria. Sedangkan pada perempuan pascamenopause, penurunan level estrogen menunjukkan efek protektif terhadap perubahan NF pada area otak ini. Kata kunci: estrogen, hiperfosforilasi protein tau, nukleus infundibularis, penuaan, testosteron

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