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Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)

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Published by Perkumpulan Obstetri dan Ginekologi Indonesia

ISSN : 23386401 EISSN : 23387335 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology Public Health

The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.

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Articles 39 Documents

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Search results for , issue "Volume. 5, No. 4, October 2017" : 39 Documents clear

The Accuration of LiquidBased Cytology and HPV DNA Test Combination as Precervical Cancer Lesion Screening Indarti, Junita; Pratama, Yuven S
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the accuracy of liquid-based cytology, HPV DNA test, and the combination of liquid-based cytologyband HPV DNA test, compared to histopathology as the gold standard of precervical cancer lesion screening. Methods: This was a cross-sectional study. The medical records of patients who came to the Women’s Health Clinic of Dr. Cipto Mangunkusumo Hospital during the period of July 2013 to December 2015 were evaluated. Results: The high risk type HPV DNA is detected in 76% CIN 1, 88.46% CIN 2, and 84.21 CIN 3 in histopathology results. The accuracy of liquid-based cytology; sensitivity 88.54%, specificity35.71%, PPV 75.89%, and NPV 57.69%. The accuracy of HPV DNA; sensitivity 81.25%, specificity 78.57%, PPV 89.66%, and NPV 64.71%. The accuracy of combination: sensitivity 94.79%, specificity 35.71%, PPV 77.12%, and NPV 75%. Conclusion: The addition of HPV DNA test increased the sensitivity from 88.54% to 94.79% because of decreasing of false negative of liquid-based cytology. This thing has showed that the combination of liquid-based cytology and HPV DNA test could the one of the option of precervical cancer lesion screening method, especially in secondary or tertier health center in Indonesia. Keywords: accuracy test, HPV DNA, liquid-based cytology, precervical cancer lesion, precervical cancer lesion screening

The Role of Tumor Necrosis Factor  (TNF ) and Matrix Metalloproteinase9 (MMP9) Serum in Preterm Premature Rupture of Membranes Ardiles, Ardiles; Desmiwarti, Desmiwarti; Bachtiar, Hafni
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the role of TNF- and MMP-9 serum in preterm premature rupture of membranes (PPROM). Methods: We used cross-sectional study design. Subjects were all pregnant women with and without PPROM who underwent checkup at Obstetrics and Gynecology Functional Medical Staff General Hospital Dr. M. Djamil and networking hospital. Results: A total of 48 subjects were enrolled in this study. The mean serum levels of TNF- in patients with PPROM 17.43 ng/ml  12.4 ng/ml and without PPROM 8.45 ng/ml  6.86 ng/ml. The mean serum levels of MMP-9 in patients with PPROM 8.77 ng/ml  4.41 ng/ml, and without PPROM 4.46 ng/ml  3.04 ng/ml. Statistical test result p value <0.05, it can be conclude there are differences in the levels of TNF- and MMP-9 serum in premature rupture of membranes and without premature rupture of membranes pregnancy of preterm. Conclusion: There are differences in the levels of TNF- and MMP-9 serum in PPROM and without PPROM.Keywords: MMP-9, premature rupture of membranes, TNF-

Radiotherapy Response of Cervical Cancer Patients at a Tertiary Referral Hospital in Indonesia Winarto, Hariyono; Supriana, nana
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the response of radiotherapy and related clinicopathologic characterictics on cervical cancer patients. Methods: This was a retrospective study. Subjects were patients diagnosed with cervical cancer stage IIA-IIIB who had undergone radiation therapy based on standard protocol in our hospital, during the period of January 2014 to December 2015. The clinical factors ofthose patients, such as age, Body Mass Index, blood pressure, hemoglobin level, blood leucocyte count, serum albumin, largest tumor diameter, the International Federation of Gynecology and Obstetrics (FIGO) staging, as well as pathologic characteristic, i.e histopathology and grading were recorded. During radiation protocol until 3months post radiation, we also noted any side effects of gastrointestinal tract, genitourinary tract, and hematologic. Evaluation of radiotherapy response was based on Response Evaluation Criteria in Solid Tumors (RECIST).  Results: A total of 123 subjects were enrolled in this study. 84 cases or 68.29% was complete response, 30 cases or 24.39% was partial response, 6 cases or 4.88% was stabile response, and 3 cases or 2.44% was progressive. Based on gastrointestinal side effect, there was no side effect or grade 0 on 99 cases (80.49%), grade 1 on 20 cases (16.26%), grade 2 on 4 cases (3.25%), grade 3 on 0 case (0%). Based on side effect of genitourinary, there was no side effect or grade 0 on 105 cases (85.37%), grade 1 on 17 cases (13.82%), grade 2 on 1 case (0.81%), grade 3 on 0 case (0%). Based on hematologic side effects, there was no side effecton 108 cases (87.80%), grade 1 on 15 cases (12.20%), grade 2 on 0 case (0%), grade 3 on 0 case (0%). Largest tumor diameter was statistically significant, with p=0.036 (RR 2.64 (1.07-6.56)). Conclusion: The majority of definitive-curative radiotherapy response on cervical cancer stage IIA-IIIB was complete (68.29%). Acute side effects involving the gastrointestinal, genitourinary, and hematologic system were commonly can be tolerable during and 3 months post radiation therapy. Clinicopathologic characteristics significantly associated with the complete response of radiotherapy was the largest tumor diameter. Keywords: largest tumor diameter, radiation response, radiationside effect

The Role of Progesterone Induced Blocking Factor in Threatened Abortion Widya, Andre C; Loho, Maria F; Wantania, John J E
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To determine the role of progesterone-induced blocking factor (PIBF) in women with threatened abortion. Methods: This was a cross-sectional study. The blood serum of two groups, the first one was women with normal gestation of  20 weeks, and the second one was those with imminent abortion in Prof. Dr. R.D. Kandou Hospital, and Subcenter Hospital in Manado, was collected. Samples were processed with PIBF ELISA-kit. Results: PIBF serum value of women in normal gestation  20 weeks is (47.15323.830)ng/ml and threatened abortion is (11.540 4.892) ng/ml, with p value = 0.000. Conclusion: PIBF serum value of women with threatened abortion is significantly lower compared to women of normal gestation  20 weeks. This study showed that PIBF has an important role in maintaining pregnancy and can be used as a biologic marker of a pathologic process in pregnancy.Keywords: early pregnancy, pregnancy immunology, progesteroneinducedblocking factor, threatened abortion

The Role of Matrix Metalloproteinase9 (MMP9) in Endometriosis Amalia, Amalia; Abdullah, Nusratuddin; Malinta, Umar
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the role of MMP-9 expression in endometriosis. Methods: The study was conducted from October 2015 to March 2016, an observational study with cross-sectional design. Samples are all endometriosis patients who underwent laparoscopic surgery in Dr. Wahidin Sudirohusodo Hospital and several other hospitals in Makassar. Samples were stored and fixed in the Grand Medika Histopathology Laboratory Makassar for examination the expression of MMP-9 using immunohistochemical methods. Conducted an analysis of 50 samples, of which 11 samples of stage II, 21 stage III samples, and 18 samples of stage IV. The data obtained and analyzed statistically using Mann Whitney and Chi Square test with a significance level of p <0.05. Results: The results reported rankings mean the expression of MMP-9 in stage I-II = 16.68, stage III-IV 27.99 (p = 0.013). There were differences in the expression of MMP-9 based on the stage. Stage I-II endometriosis had a more positive 2 expression of MMP-9 (45.5%), stage III-IV endometriosis have more positive 3 expression of MMP-9 (59.0%). The results of chi square test (p = 0.043). Conclusion: Higher expression of MMP-9 is significantly associated with higher degree of endometriosis. Keywords: matrix metalloproteinase-9, stages of endometriosis

Should All Patients With Endometriosis Undergo Surgery? Djuwntono, Tono
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

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The Menopausal Symptoms of Paramedics at a Tertiary Care Center Kumaat, Toar A; Loho, Maria F T; Suparman, Eddy
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To assess paramedic menopausal symptoms on theinpatient unit and outpatient unit.Methods: This was a cross sectional study. Data collect by fill thequestioner, the questioner fill by menopausal paramedic on Prof. Dr.R. D. Kandou Manado Hospital from October 2016 to January 2017.Data were analyzed using SPSS 22.0 for Windows.Results: Of 60 paramedics, 30 were divided to inpatient unit andthe other 30 were divided to outpatient unit. By the menopauserating scale, somatic and urogenital complaint in statistical testhave no significant differences. Psychology complaint with a moderatecomplaints on inpatient unit have 19 paramedic (63%) and12 paramedic (40%) on outpatient paramedic, in statistical havea significant differences (x2=9.62, p=0.022). On the total scoremenopausal complaints, the moderate complaints 18 paramedic(60%) on the inpatient unit and the minor complaints 21 paramedic(70%) on the outpatient unit, in statistical have a significantdifferences (x2=6.97, p=0.031).Conclusion: There is no significant difference in somatic andurogenital complaints on paramedic inpatient unit and outpatientunit. There is a significant difference in psychological complaintsand total score menopausal complaints on paramedic inpatientunit and outpatient unit.[Indones J Obstet Gynecol 2017; 5-4: 208-212]Keywords: menopause, menopause rating scale, paramedic

Postplacental IUCD CuT380A: Acceptability, Effectivity and Side Effects Situmorang, Herbert; Setijanto, Ivanna T; Affandi, Biran
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To evaluate the acceptability, effectivity and side effects of Postplacental IUCD after vaginal delivery at Dr. Cipto Mangunkusumo Hospital (RSCM) after 6 month of insertion. Methods: A prospective study was conducted at RSCM Jakarta during the period of August to October 2012. Postplacental IUCD was inserted into the subjects’ uterus until it reached the fundus. Follow up was done at 40-42 days and 6 months after delivery.  Results: A total of 234 women were recruited in this study, with 19.2% loss of follow up. No significant difference on subjects characteristics who came and loss of follow up in this study. Expulsion was experienced by 5.1% subjects (total expulsion 4.1% and partial 1%) at the first visit on 40-42 days and 7.5% subjects (total expulsion 0.6% and partial 6.9%) at the second visit, after 6 months. 9.3% subjects had the IUCD removed at the first and second visit. Among all of the subjects who had the IUCD removed by request or had the expulsion, 61% were willing to do reinsertion. The effectivity of IUCD was 100%, with 68.9% subjects was still breastfeeding. The side effects were vaginal discharge (23%), dysmenorrhea (4-21%), and spotting (2-10%).  Conclusion: The acceptability and effectivity of postplacental IUCD after 6 months were 86.8% and 100%. Cummulative expulsion rate were 12.6%, and the most common side effects were vaginal discharge, dysmenorea, and spotting. Keywords: acceptability, effectivity, expulsion rate, IUD, postplacenta

The Association of Bladder Wall Thickness with Severity of Symptoms in Patients with Overactive Bladder Adrian, Ronny; Bernolian, Nuswil; Fauzi, Amir; Saleh, Irsan
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the association of bladder wall thickness (BWT) with severity of symptoms in overactive bladder patients in Obstetrics and Gynecology Department Dr. Mohammad Hoesin general hospital Palembang. Methods: An analytical observational study was conducted at Gynecology clinic Dr. Mohammad Hoesin General Hospital Palembang from November 2015 to August 2016. Data were analyzed with SPSS 16.0 for Windows. Bivariate analysis with the Chi square and association Rank-Spearman test was used to assess the association between BWT and visual analog scale (VAS). Results: Fourty subjects were included in the study. The mean BWT in the overactive bladder group was thicker compared to those without overactive bladder (5.8522  0.5783 vs 5.2176  0.67937). There was significant association between BWT and overactive bladder complaints. Abnormal group (5mm) had 12 times risk of overactive bladder compared to normal sample (5mm) (p = 0.029, RR = 12). Conclusion: Thus, the thickness of the urinary bladder wall measured with ultrasound examination (USG) can be used to assess the status and degree of urinary disorders in women with complaints of painful urinate and urinary disorders.  Keywords: bladder wall thickness, detrusor overactivity, overactive bladder, visual analog scale

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eko subaktiansyah

Contact Email
eko.subaktiansyah@gmail.com

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support@inajog.com

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Location
Kota adm. jakarta pusat,

Dki jakarta

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