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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,731 Documents
The Rise of Inhibin A Serum Level in Preterm Labor Oky Haribudiman
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: The purpose of this study was to measure inhibin A serum level in women with preterm delivery, thus determining any correlation between inhibin A serum and gestational age in preterm delivery. Method: The design of our study was cross sectional with 36 subjects who came to Dr. Hasan Sadikin Hospital, Bandung and six satellite hospitals in July-August 2011 and met inclusion-exclusion criteria. Inhibin A serum level was measured with ELISA. Inhibin A serum level in preterm labor and was compared using independent t test, and correlation between inhibin A serum level and gestational age in patients with preterm labor was calculated using Pearson correlation test. Result: Characteristics test in both groups showed that both are homogeneous and comparable. The mean inhibin A serum level in preterm labor was higher (845.733 pg/ml) compared with preterm gestation (568.203 pg/ml) (p = 0.025). There was a significant correlation between inhibin A serum level and gestational age in preterm labor (p = 0.023) with a correlation coefficient of 0.38, indicating a moderate positive relationship. Conclusion: Inhibin A serum level in preterm labor was higher than preterm pregnancy. In preterm labor, inhibin A serum level increases with gestational age. [Indones J Obstet Gynecol 2011; 35-3: 110-4] Keywords: preterm delivery, inhibin A serum level
Comparison of Macrophage Migration-Inhibitory-Factor (MIF) Serum Level between 28 - 36 Weeks of Pregnancy and Delivery Novy Riyanti
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To analyze the differences in Macrophage Migration Inhibitory Factor (MIF) serum level between 28 - 36 weeks of pregnancy and delivery, and determine the serum level of Macrophage MIF as a risk factor for preterm labor. Methods: The design of our study was cross sectional of 72 subjects who met the inclusion- and exclusion-criteria that came to Dr. Hasan Sadikin Hospital, Bandung and six satelite hospitals (in July - August 2011). Macrophage Migration Inhibitory Factor (MIF) level was measured with ELISA. Comparison of mean serum levels of MIF between 28 - 36 weeks of pregnancy and delivery was analyzed using the Mann Whitney test. MIF level, which is a risk factor for preterm delivery, was calculate with a prevalence ratio (PR) based on ROC curve. Results: Characteristics test in both groups showed homogeneous and comparable data. The mean levels of Macrophage Migration Inhibitory Factor (MIF) in 28 - 36 weeks of delivery was higher (54.433 ng/ml) compared with 28 - 36 weeks of gestation (31.765 ng/ml) with p ≤ 0.001. MIF levels > 37.684 ng/ml had a risk for preterm labor incidence 3.35 times greater than that of ≤ 37.684 ng/ml. Conclusion: Serum levels of Macrophage Migration Inhibitory Factor (MIF) at delivery was higher than that of at 28 - 36 weeks pregnancy. MIF levels > 37.684 is a risk factor for preterm labor. [Indones J Obstet Gynecol 2011; 35-3: 115-8] Keywords: Macrophage Migration-Inhibitory-Factor (MIF), preterm labor
Levonorgestrel Concentration in a Single Rod Implant Users for Six Months Eka R. Gunardi
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: This research was conducted to measure levonorgestrel serum concentration Monoplant® after six months of usage. Method: Thirty healthy women, 20 - 40 years old, and after been proven for fertility, had implants on their body. Levonorgestrel serum levels were measured monthly from the first month to the sixth month. Result: Levonorgestrel serum concentration was still above 200 pg/ml until the sixth month. First month and second month serum concentration was not recorded while data for the following months were 338.9 pg/ml, 424.8 pg/ml, 320.3 pg/ml, and 337.5 pg/ml. Conclusion: Levonorgestrel serum concentration in Monoplant® users was still above contraceptive level until six months. [Indones J Obstet Gynecol 2011; 35-3: 122-7] Keywords: single rod implant Monoplant®, levonorgestrel serum concentration
The Role of Dominant Follicular Diameter and LH in Predicting Ovulation in Cycle with Clomiphene Citrate Budi Wiweko
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To improve diagnostic method to predict ovulation in cycle with clomiphene citrate. Method: This diagnostic research was done in RSUPN Dr. Cipto Mangunkusumo between January 2011 - October 2011 with 31 women who taking CC 50 mg/day and 30 women with normal cycle. Result: Affecting with ovulation in the two groups, it was found that in groups with CC, the follicle diameter is 24.33 ± 3.87 mm with LH 14.21 ± 7.95 IU/l, meanwhile in normal group, follicular diameter is 17.62 ± 3.45 mm with LH 14.42 ± 5.91 IU/l. Cut-off point for follicular diameter simultaneously with ovulation determined by ROC curve was found in 24.33mm (AUC 0.67, sensitivity 0.64, specificity 0.56), meanwhile the cut-off for LH is 14.40 IU/l (AUC 0.61, sensitivity 0.57, specificity 0.43). Conclusion: In group with CC, ovulation occurred in bigger follicular diameter than normal cycle, while LH does not different significantly. [Indones J Obstet Gynecol 2011; 35-3: 128-9] Keywords: clomiphene citrate, follicular diameter, luteinizing hormone
Etiologies of Male Infertility in Dr. Cipto Mangunkusumo Hospital, Jakarta Doddy H. Seno
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To have description about the etiologies of male infertility in Dr. Cipto Mangunkusumo Hospital. Method: This was a retrospective study of 315 male infertility patients treated at the Urology Department Dr. Cipto Mangunkusumo Hospital from January 2009 to June 2011. Result: There were 78 patients excluded from the analysis due to incomplete or missing data. The available data consisted of 237 males, with a median age of 35 years old. The median duration of infertility was 4 years. Primary infertility was identified in 89.4% and secondary infertility in 10.6% of all cases. Semen analysis results were classified as normal 2.5%, aspermia 1.3%, azoospermia 41.4%, multiple abnormal parameters 38.0%, single abnormal parameter (oligozoospermia 7.6%, asthenozoospermia 6.8%, teratozoospermia 2.1%), and cryptozoospermia 0.4%. From 237 subjects, there were 39 men (15.9%) with multiple etiologies of male infertility. The most common etiology in this study was varicocele (48.5%). Other etiologies were idiopathic 27.8%, acquired factors 14.3%, obstruction 8.0%, congenital anomalies 6.3%, urogenital infection 2.5%, sexual factors 2.1%, endocrine disturbance 2.1%, no demonstrable cause 1.3%, and other abnormalities 0.8%. This study also found Y-chromosome microdeletions in 2.5% of subjects or 6/98 (6.1%) of azoospermic patients. Lifestyle factors associated with male infertility were smoking 31.6%, alcohol consumption 13.4%, hot-bathing 6.7%, and sauna 2.9%. Conclusion: There are numerous possible contributing factors of male infertility, and varicocele was the most commonly identified etiology in this study. Some of our patients were presented very late for infertility treatment, therefore prompting the necessity to increase general awareness of male infertility in the society. [Indones J Obstet Gynecol 2011; 35-3: 130-4] Keywords: azoospermia, varicocele, risk factor
Laparoscopic Robotic Surgery in Gynecology Wachyu Hadisaputra
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To know the development and application of robot assisted laparoscopy in gynecology. Method: Literature review. Result: Laparoscopy procedure has been widely used since the last three decades where minimally invasive surgery cases and demands increase in urology, cardiac surgery, general surgery, and particularly, gynecology. To date, laparoscopy has developed into robot-assisted laparoscopy due to needs of precise dissection of delicate structures, procedures which requires sophisticated technique, and surgeon’s fatigue through the laparoscopy procedure. There are three robotic system which are commercialized and had been approved by FDA: AESOP, ZEUS, and Da Vinci, the latest robotic system which is used worldwide nowadays. There are advantages of robotic systems and conventional laparoscopy to open surgery laparotomy, such as diminished morbidity rate; less esthetical incisions; decreased post and intra operative blood loss, postoperative pain, use of pain medication, less cosmetic problems, and shorter length of hospital stay. Advantages of robotic surgery compared to conventional laparoscopy and laparotomy; include improved dexterity, more precise and accurate articulation, reduced tremor and surgeon’s fatigue, and better visualization of the operating field because of 3D image. Robotic system has drawbacks such as limited area of surgery field in trocar-placing to avoid collision of the robotic arms, longer operative time, and a higher cost. Conclusion: The major drawback of robot-assisted laparoscopy is in the term of cost; because of the high cost of robotic system; which could be overcome by a lower morbidity rate, less incisional aesthetic problem, less total intra operative blood loss, decreased demand of analgesics post operative, and shorter length of hospitalization stay and recovery time; as compensation of the high cost of robotic system. Further researches to study about the learning curve of robotic laparoscopy to achieve a faster operative time are needed. A longer operative time in robotic system can be anticipated with accurate simulation training in robotic system. There is also a need for further researches to discuss the total peri-operative cost. [Indones J Obstet Gynecol 2011; 35-3: 146-50] Keywords: laparoscopy, robotic system, robot-assisted, Da Vinci system, learning curve, gynecology
Correlation of Total Antioxidant Capacity Measured by Ferric Reducing Ability of Plasma (FRAP) Assay with the Severity of Preeclampsia Martin Hermawan
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 4, October 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To analyze correlation between total antioxidant capacity measured by Ferric Reducing Ability of Plasma (FRAP) assay with severity of preeclampsia. Method: The cross sectional method was used in this study to compare TAC of four different groups of study, consists of normal pregnancy, mild preeclampsia, severe preeclampsia and eclampsia. The study consisted of 15 women in each group. All of the subjects met the inclusion criteria and were admitted to Dr. Hasan Sadikin Hospital and it’s district hospital. The study was conducted from August until September 2011. 3 ml blood samples were taken and were measured by FRAP assay in the laboratory PRODIA Jakarta. Result: There was no significant difference (p
Distention Media in Hysteroscopy for Diagnostic and Operative Procedure Wachyu Hadisaputra
Indonesian Journal of Obstetrics and Gynecology Volume. 34, No. 3, July 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: Hysteroscopy is the "gold-standard" procedure used to describe the morphology of uterine cavity and the presence of intrauterine lesions and it is a minimally invasive intervention that can be used to diagnose and treat many intrauterine and endocervical problems. Hysteroscopy requires uterine distention for the effective visualization of the uterine cavity and the clearing of blood and tissue debris. Options for uterine distention include insufflation with carbon dioxide (CO2) gas, and instillation with electrolytic and nonelectrolytic liquid distention media. In this review, we would like to review known available distending media and its characteristics for diagnostic and operative hysteroscopy. Method: Literature review. Conclusion: Carbon dioxide and normal saline are the most preferable distention media for diagnostic hysteroscopy. There is no significant difference between these medium in terms of visualization quality, but most practitioners prefer to use normal saline because of it’s availability and acceptability, quick performance, fewer additional procedures, more satisfaction rate, and good visualization. Low viscosity fluids are the most preferable media for operative hysteroscopy. Low viscous-electrolytic fluids, mostly normal saline is recommended in operative cases using mechanical, laser or bipolar energy that requires no electricity. Nonelectrolytic low-viscosity fluids are most preferable for extensive operative procedures using electrosurgery. Mannitol are chosen over glycine or sorbitol when using monopolar electrosurgery. [Indones J Obstet Gynecol 2010; 34-3: 150-4] Keywords: hysteroscopy, distention media, diagnostic procedure, operative procedure
Serum Magnesium Ion Content in 32-36 Weeks Preterm Labor Patients in Dr. Mohammad Hoesin Hospital Palembang Shanti A. Diani
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 4, October 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To determine the average levels of serum magnesium in 32-36 weeks of preterm labor patients and to compare the average of serum level of magnesium serum in preterm delivery 32-36 weeks with an average content of magnesium ions in normal delivery. Methods: The study is an observational descriptive cross-cut design to determine level of magnesium serum at 32-36 weeks of preterm labor. Result: Samples of this study were patients with preterm labor who were treated at the Department of Obstetrics and Gynecology in Dr. Mohammad Hoesin Palembang from January 1st, 2009 until July 31st, 2010. The number of samples was 33 subjects. Most subjects were in the range of 20-35 years of age. The largest parity in the preterm group was 0, namely 14 subjects (42.5%), while in the normal pregnancy group it was 1, viz. 12 subjects (36.4%). Conclusion: Based on the results of studies, the magnesium levels of 32-36 weeks preterm labor group was lower than the normal delivery group. The average of magnesium level in preterm labor group was 1.57 ± 0.18, while in the normal delivery group, it was 1.88 ± 0.23. There was a statistically significant difference found on magnesium levels in both groups (p
The Correlation of Early Initiation of Breastfeeding with Achievement of Exclusive Breastfeeding and Corresponding Factors Marina Tamara
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 4, October 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To study the role of early breastfeeding in time of placental expulsion, breast milk secretion and achievement of exclusive breastfeeding. Method: A prospective cohort study was carried out at Dr. Cipto Mangukusumo General Hospital Jakarta delivery suite in January 2011. Total sample was 68 and divided into 34 sample who was conducting early initiation of breastfeeding and another 34 who did not. Time computation was conducted by the time of placental expulsion and breast milk secretion and also observation within the first 6 month to see whether exclusive breastfeeding was achieved or not. Result: From the study the obtained patients’ characteristic data were 38.2% aged 25-29 years old, 52.9% multiparity, 72.1% having middle education degree (Junior High School to Senior High School graduates), 39.7% on low economic level, and mostly unemployed (73.5%). From total sample, it was found 48 patients (70.6%) who succeded in managing exclusive breastfeeding and 20 patients (29.4%) who did not with 50% stated working as the reason. Conclusion: Early initiation of breastfeeding (EIB) has correlation with duration of placental expulsion, duration of breastmilk secretion and achievement of exclusive breastfeeding. The mean time needed to achieve early initiation of breastfeeding was 46.5 minutes. The mean time of placental expulsion in patient with EIB was 7.35 minute (SD ± 2.695) there was significant correlation between EIB with the time of placental expulsion (p=0.005). The mean time of breastmilk secretion in patient with EIB was 10.65 hours (SD ± 4.947) and there was significant correlation between EIB with the time of breastmilk secretion (p=0.000). It was found significant correlation on data analysis between patients who succeeded to manage EIB with achievement of exclusive breastfeeding (p=0.033). There is also statistically significant correlation between working mothers and achievement of exclusive breastfeeding (p= 0.005) with comparison of probability to have exclusive breastfeeding success rate between unemployed mother and employed mother. Being 1.8 times (RR: 1.800, IK 95% : 1.054-3.073) with cofounding factor is employment status. [Indones J Obstet Gynecol 2011; 35-4: 161-6] Keywords: early initiation of breastfeeding, exclusive breastfeeding, time of placental expulsion, time of breast milk secretion

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