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Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)

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Published by Perkumpulan Obstetri dan Ginekologi Indonesia

ISSN : 23386401 EISSN : 23387335 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology Public Health

The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.

Arjuna Subject : -

Articles 1,731 Documents

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Ki-67 Expression is Correlated with Cyst Size and Stage of Endometriosis Muhammad Alif; Ruswana Anwar; Adhi Pribadi
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objectives: To analyze the association between Ki-67 expression with the cyst size and stage of endometriosis, and the correlation strength between them. Methods: A cross-sectional analytic observational study involving 56 paraffin blocks from subjects diagnosed with endometriosis, who had undergone laparotomy or laparoscopic surgery. The study is conducted in Dr. Hasan Sadikin Hospital in September-November 2012. Results: Shows a significant association between Ki-67 expression and the size of endometriotic cyst (p < 0.0001), also with a strong correlation (r = 0.55) according to Guilford criteria. There is also a significant association between Ki-67 expression and the endometriosis stage (p < 0.0001), with a strong correlation (r = 0.564) according to Guilford criteria. Conclusion: Ki-67 expression is correlated with the cyst size and stage of endometriosis. [Indones J Obstet Gynecol 2013; 1-3: 124-8] Keywords: endometriosis stage, endometriotic cyst size, Ki-67

Total Testosterone Level is Lower in Women Consuming Combined Oral Contraception with Impaired Sexual Function Yuniarty Amra; Joseph L Tumeida; Edi Hartono
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objectives: The aim of this research was to assess the relationship between total testosterone level and female sexual function based on Female Sexual Function Index (FSFI) among the acceptors of combined oral contraceptive pill. Methods: The research was conducted in BLU of Dr. Wahidin Sudirohusodo Hospital and several teaching hospitals in obstetrics and gynecology sections of Medical faculty, Hasanuddin University from October to December 2012. This study assessed sexual function among 60 women as the acceptors of combined oral contraceptive pill. Sexual function was assessed using FSFI questionnaire which had been validated in several countries. This research used cross sectional design and the sample was selected using consecutive sampling method. The data were processed using SPSS with independent t test of the significant level of 0.05. Results: The results of the research reveal that total testosterone level among the acceptors of combined oral contraceptive pill who have impaired sexual function is low. The result of the correlation test between testosterone level and FSFI score indicates a significant level (p<0.05) with a correlation coefficient of (r) = 0.737. The testosterone level of female who have impaired sexual function is significantly different (p<0.05) from women who have normal sexual function. The cut off testosterone level that could indicate the occurrence of sexual dysfunction is 12.4 ng/dl. Conclusion: The total testosterone level among the acceptors of combined oral contraceptive pill who have impaired sexual function is lower than others who have no impaired sexual function. [Indones J Obstet Gynecol 2013; 1-3: 129-33] Keywords: combined oral contraceptive pill, FSFI, sexual function, total testosterone level

Levels of Thyroid Peroxidase Antibodies is Higher in Threatened Abortion I Nyoman A. Sanjaya; Syarif T Hidayat
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To assess the relationship between the incidence of threatened abortion with serum levels of TPO antibodies. Methods: This was cross-sectional study involving subjects 40 cases and 40 controls. The study was conducted September 2012 to November 2012. The difference in the levels of thyroid peroxidase antibody was tested by Mann-Whitney test. Result: In this study, hypothyroidism was found only in the abortion group, as many as 6 subjects (15%) and subclinical hypothyroidism was more prevalent in threatened abortion group, found in 2 people (5%), compared to normal pregnant group, found in only 1 person (2.5%). This study revealed a significant difference in the mean levels of TPO antibodies in the threatened abortion and normal pregnancy group. The mean levels of TPO antibodies in threatened abortion group was 91.76 Â± 133.18 IU/ml with the lowest level of 14.41 IU/ml and the highest levels of 534.47 IU/ml while in the normal pregnancy group found an average 12.97 Â± 3.91 IU/ml with the lowest value 2.02 IU/ml and the highest value of 20.78 IU/ml. In this study, subjects with TPO antibody levels â‰¥ 125 IU/ml, all of them experienced threatened abortion (n = 7) and found the risk of miscarriage by 2.212-fold compared with subjects with TPO levels < 125 IU/ml. Conclusion: There are differences in the levels of TPO antibodies in patients with threatened abortion and in normal pregnancies, with average levels of TPO antibodies in imminent abortion group is higher than normal pregnancy group. There is a relationship between TPO antibody levels â‰¥ 125 IU/ml with the incidence of threatened abortion, with the risk of threatened abortion increasing 2.212 times. [Indones J Obstet Gynecol 2013; 1-3: 134-8] Keywords: threatened abortion, thyroid peroxidase antibody (TPO)

The Hemoglobin Levels and Hematocrit Decrement is less in Severe Preeclampsia Patients Undergoing Caesarean Section with B-Lynch as Prophylaxis Ahmad Parwis; Anita D Anwar; Setyorini Irianti
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To analyze the differences between the reduction in hemoglobin and hematocrit level in severe preeclampsia patients who have had Caesarean section with and without B-Lynch prophylaxis. Method: The design of the study was an experimental analytic with Randomized Control Trial (RCT). Thirty patients who came to Dr. Hasan Sadikin Hospital, Soreang Hospital, and Cibabat Hospital during 11 July - 25 September 2012 and met inclusion criteria were selected and divided into two groups. The first group were caesarean section with B-Lynch prophylaxis, the second one were without BLynch prophylaxis. The sample were taken with simple random sampling. Each patient were examined for hemoglobin and hematocrit level before and 6 hour after C section. The data was analyzed by t-test and Mann Whitney test. Result: There were significant differences (p <0.05) on the decrease of hemoglobin and hematocrit level between patient who were performed B-Lynch prophylaxis and those who were not (7.98% vs 19.75%; p = 0.001 and 9.02% vs 18.28%, p = 0.013, respectively). Conclusion: The decreasing hemoglobin and hematocrit level before and 6 hour after C section is less in patient with severe preeclampsia who had caesarean section with B-Lynch prophylaxis compared to cesarean section without B-Lynch prophylaxis. [Indones J Obstet Gynecol 2013; 1-3: 139-44] Keywords: B-Lynch, postpartum haemorrhage, preeclampsia

Total Serum Level of Calcium and Ion Calcium is Lower in Hypotonic Uterine Inertia Josef Wattimury; Wiryawan Permadi; Edwin Armawan
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objectives: To know the correlation between total and ion serum calcium level with the uterine contractility of laboring patient. Methods: This is a cross-sectional analytic correlative study measuring the strength of correlation of total and ion calcium serum level between groups with hypotonic uterine inertia - and normal labor. Each group consists of 20 subjects who met inclusion criteria and presented to Dr. Hasan Sadikin Hospital in August - September 2012. Statistical analysis was performed by using Eta (Î·) coefficient. Results: Mean total calcium serum level on hypotonic uterine inertia is 6.66 mg/dl, while mean of total calcium serum level on normal labor is 8.56 mg/dl, with Eta (Î·) correlation coefficient 0.721. Mean ion calcium serum level on hypotonic uterine inertia is 4.14 mg/dl, while mean of total calcium serum level on normal labor is 4.92 mg/dl, with Eta (Î·) correlation coefficient 0.802. Conclusion: Total serum level of calcium and ion calcium in hypotonic uterine inertia is lower than the level of which in normal labor. There is a strong correlation between total and ion serum calcium level with uterine contractility, the Eta (Î·) correlation coefficient are 0.721 and 0.802 respectively. [Indones J Obstet Gynecol 2013; 1-3: 145-8] Keywords: hypotonic uterine inertia, ion serum calcium level, normal labor, total serum calcium level

Risantoâ€™s Formulas is more Accurate in Determining Estimated Fetal Weight Based on Maternal Fundal Height Hanifah I Titisar; Risanto Siswosudarmo
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objectives: To compare the accuracy of Johnsonâ€™s and Risantoâ€™s formulas in determining estimated fetal weight based on maternal fundal height (FH). Methods: This was a cross sectional study, consisting of 655 pregnant women from Dr. Sardjito Hospital and affiliated hospital sat 37-42 weeks of gestation. Fundal height was measured from the symphisis to the top of uterine fundus, using inverted unelastic flexible tape. EFW based on Johnsonâ€™s and Risantoâ€™s formulas were compared with the actualbirth weight. Wilcox on analysis was used for statistical analysis. Results: Mean EFW of Johnsonâ€™s formula was 3136 Â± 392.2 grams and EFW of Risantoâ€™s formula was 3056 Â± 322.5 grams and mean actual birth weight was 3021 Â± 341.1 grams. The mean difference between EFW of Johnsonâ€™s formula and the actual birth weight was 156.1 Â± 107.3 grams, and mean difference between EFW of Risantoâ€™s formula and the actual birth weight was 100.8 Â± 86.1 grams. Those two differences was statistically significant (p=0.001). Conclusion: This study showed that Risantoâ€™s formula was more accurate than Johnsonâ€™s in predicting birth weight based on the maternalâ€™s fundal height. [Indones J Obstet Gynecol 2013; 1-3: 149-51] Keywords: actual birth weight, fundal height, Johnsonâ€™s formula, Risantoâ€™s formula

The Risk of Urinary Tract Infection in Post-Operative Pelvic Organ Prolapse is Increasing in Patients with Shorter Urethral-Anal Distance Emir Fakhrudit; Amir Fauzit; Kms Yusuf Effendy; Theodorus Theodorus
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objectives : The purpose of our study was to find the correlation between urethral-anal distance and urinary tract infection (UTI) after surgery for grade III and IV uterine prolapse. Methods : Cross sectional study of 57 consecutive women who underwent surgery for grade III and IV uterine prolapse Fisher exact test was used to determine independent risk factors. Results : Eight (14%) women developed a UTI. The risk of UTI was significantly increased in women whose distance between the urethra and the anus was less than 50.27 mm, with PR: (95%Cl): 43.75 (6.05-303.61) and p: 0.001. Conclusion: There is correlation between urethral-anal distance and urinary tract infention (UTI) after surgery for grade III and IV uterine prolapse. [Indones J Obstet Gynecol 2013; 1-3: 152-5] Keywords: cystocele, pelvic organ prolapse, rectocele, urinary tract infection, uterine prolapse

Caspase-3 can not be Used to Predict the Response to Neoadjuvant Chemotherapy Regiment PVB in Cervical Cancer Stage IB-IIA Ediwibowo Ambari; Hariyono Winarto; Bambang Sutrisna; Budiningsih Siregar
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objectives: To determine the factors that may be used as the prognostic parameter for the therapeutic efficacy of neoadjuvant chemotherapy, which can be used to revising the management of early stage cervical cancer patients with large lesions. Methods: This was a retrospective cohort study. The study was conducted in the Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, University of Indonesia. The subjects were 15 cervical cancer stage IB2 and IIA patients with lesionsâ€™ size of > 4 cm, who would be treated with neoadjuvant chemotherapy, consisted of cisplatin 50 mg/m2, vincristine 2 mg/m2 and bleomycin 15 mg regiment. The patientsâ€™ response would be evaluated after completing 3 series of chemotherapy. Data was retrieved from medical records and cervical biopsy paraffin blocks and examined histopathologically using IHC staining to see expression of caspase-3 with histoscore assessment score. Data was analyzed by univariate, bivariate analysis. Results: Response to PVB neoadjuvant chemotherapy was found in 5 out of 15 patients. None of the clinicopathology variables can be used to predict response to therapy. Expression of caspase-3 as a marker of apoptosis, can not predict the response of the therapy before administrating neoadjuvant chemotherapy either. There is a significant difference between the levels of caspase-3 in epidermoid carcinoma with adenocarcinoma, with p value of 0.02 (RR 6;95% CI 1.69-21.26). Conclusion: Clinicopathologic factors and the expression of caspase-3 before getting chemotherapy neoadjuvant can not predict the succeed of the therapy. [Indones J Obstet Gynecol 2013; 1-3: 156-60] Keywords: caspase -3, clinicopathologic, early-stage cervical cancer lession in large, neoadjuvant chemotherapy response to therapy

Management of Pseudomyxoma Peritonei Syndrome during Pregnancy Hanny Aditanzil; Bayu Mahendra; Ketut Suwiyoga
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objectives: To improve skill in making a diagnosis and management of pseudomyxoma peritoneum originating borderline mucinous ovarian tumor during pregnancy. Methods: Case report. Conclusion: Diagnosis of pseudomyxoma peritoneum during pregnancy is difficult before surgery. Management is based on grade of malignancy and gestational age of pregnancy. [Indones J Obstet Gynecol 2013; 1-3: 161-5] Keywords: mucinous tumor, pregnancy, pseudomyxoma peritoneum

Management of Abnormal Cervical Cytology: Atypical Squamous Cells of Undetermined Significance (ASC-US) and Atypical Squamous Cells cannot exclude High Grade Intraepithelial Lesion (ASC-H) Fitriyadi Kusuma; Mediana s. Liedapraja
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To review for the management of abnormal cervical cytology: atypical squamous cells of undetermined significance (ASCUS) and atypical squamous cells cannot exclude high-grade intraepithelial lesion (ASC-H) as a treatment of cervical precancerous lesions in order to avoidexcessive treatment, reduce of unnecessary examinations and to provide cost effectively. Method: Literature study on published literatures and studies about the management of cervical cytology. Conclusion: The results of ASC-US cervical cytology and ASC-H is aninitial screening to detect precancerous cervical lesions. Definitive therapy should be done when finding a low-grade lesions (LSIL) and high degree of lesion(HSIL) squamous intraepithelial. A clinician expected to understand the natural history of HPV infection and the management of precancerous cervical lesions properly. [Indones J Obstet Gynecol 2013; 37-3: 166-170] Keywords: ASC-H, ASC-US, cervical cytology abnormalities, cervical precancerous lesion.

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eko subaktiansyah

Contact Email
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