Journal Of Widya Medika Junior
Journal of Widya Medika Junioris our faculty's very first project in publishing the students' research, making them available for both students and faculty members to read. It is an endeavour to nurture our students' passion in doing scientific research through which process they will be encouraged to develop critical thinking, academic writing, an in-depth analysis of a particular topic using scientific method, and eventually produce knowledge.
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<![CDATA[THE EFFECT OF CREAM-BASED APPLICATION OF MORINGA LEAF (MORINGA OLEIFERA) EXTRACT ON THE INCISION WOUND HEALING ON WHITE RAT MANUSCRIPT ]]>
<![CDATA[Felix Kurniawan Adithia]]>;
<![CDATA[Dave Gerald Oenarta]]>;
<![CDATA[Bernadette Dian Novita Dewi]]>
<![CDATA[ JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 4 (2022): October ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA ]]>
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DOI: 10.33508/jwmj.v4i4.3658
<![CDATA[Background: High injury incidence is a consideration of wound prevention with the prevalence of iris/torn/puncture injuries 20.1% in 2018. Indonesian people have a high level of confidence in traditional medicine and one of them is Moringa. Moringa phytochemical content has the potential to speed up the healing process of incision wounds.Purpose: This study aims to determine the effect of moringa leaf extract cream with concentrations of 5%, 15%, and 45% on the healing process of white rat incision wounds (Rattus norvegicus) by assessing the healing phase and using the Bates-Jensen Wound Assessment Tool (BWAT).Method: This research is experimental with a post-test-only control group design. Sampling by simple random sampling method and calculated using Federer's formula with the number of samples of 30 white rats divided into five groups, namely two groups of control and three treatment groups with 6 white rats in each group for 21 days.Results: In the analysis of BWAT score data with the MANNOVA test, there were insignificant results on day 1 (p=0.840) and day 7 (p=0.888), then there were significant results on day 14 (p=0.001). Post-hoc results showed significant differences between the negative control group and positive control over the 45% moringa leaf extract creaming group. In the analysis of healing phase data with the Kruskal-Wallis’s test, significant results were obtained in the coagulation phase (p=0.000) and the proliferation phase (p=0.001). The results of the Mann-Whitney test in the coagulation phase showed significant differences between the control and treatment groups while in the proliferation phase there were significant results between the control group and the treatment and there were no meaningful differences between the treatment groups.Conclusion: There is no significant difference in effectiveness between the administration of moringa leaf extract cream to accelerate the healing process of incision wounds.]]>
<![CDATA[THE EFFECTIVENESS OF HAEMATOCOCCUS PLUVIALIS EXTRACT ON SUPEROXIDE DISMUATSE LEVEL OF RATTUS NORVEGICUS POST ULTRAVIOLET B EXPOSURE ]]>
<![CDATA[Angeline G Irwan]]>;
<![CDATA[Endang Isbandiati]]>;
<![CDATA[Dave G Oenarta]]>
<![CDATA[ JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 4 (2022): October ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA ]]>
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DOI: 10.33508/jwmj.v4i4.4337
<![CDATA[Background : Exposure of ultraviolet B from the sun can trigger the formation of free radicals, and causing oxidative damage on skin. One of the treatments for skin damage caused by UV B exposure is using 2% glutathione cream. and using green algae Haematococcus pluvialis extract cream.Objective : To analize the differences in the effectiveness of giving Haematococcus pluvialis extract cream and glutathione cream on white rats post ultraviolet B exposure.Method : The type of research used in this study is experimental with the post test only control group design approach. The number of samples was calculated using the Federer formula, with a total sample of 30 white rats that are devided into 6 groups. The parameter is superoxide dismutase enzim that is measured using spectrophotometer.Result : As a normal control group, 5 white rats were not exposed to UV B and were not given any cream while 25 white rats were exposed to UV B light for 2 hours in 14 days, then 5 rats as negative control group were not given any cream, 5 rats as positive control group were given 2% glutathione cream, 5 rats were given 10% Haematococcus pluvialis cream, 5 rats were given 20% Haematococcus pluvialis cream, and 5 rats were given 30% Haematococcus pluvialis cream. The results of this research showed that rats that were given 20% and 30% Haematococcus pluvialis cream has higher superoxide dismutase levels than the other groups.Conclusion : Haematococcus pluvialis extract cream is effective in treating oxidating damage on white rats post ultraviolet B exposure.]]>
<![CDATA[THE CORRELATION OF SERUM ALBUMIN LEVELS AND STAGES OF DECUBITUS IN INPATIENTS AT DR. SOETOMO REGIONAL GENERAL HOSPITAL OF SURABAYA ]]>
<![CDATA[Triesya Permata Sari]]>;
<![CDATA[Ari C Muliono]]>;
<![CDATA[Dewa A L Dewi]]>
<![CDATA[ JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 4 (2022): October ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA ]]>
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DOI: 10.33508/jwmj.v4i4.3699
<![CDATA[Introduction : The prevalence of decubitus ulcers in Asia is amounted to 2.7%-16.8%, and in Indonesia, there was a 40% prevalence of decubitus ulcers in 2017. In 2017, the prevalence of decubitus in Bandung was found to be 10.8%. Consequently, the number of active cases and deaths of decubitus ulcers reached 48%. Therefore, efforts to reduce the number of decubitus ulcers are urgently needed, thereby preventing the risk of decubitus severity. Objective: To evaluate the correlation of serum albumin levels and stages of decubitus in inpatients at Dr. Soetomo Regional General Hospital of SurabayaMethod: This research was successfully carried out by means of observational analytics, with a cross-sectional research design. Moreover, this research data were derived from medical record data of inpatients at Dr. Soetomo Regional General Hospital of Surabaya in the period of January 2018 – December 2020, with a total of 144,002 patients. 197 decubitus patients in Pandan I and Pandan Wangi rooms were involved in the sample selection process. Based on the inclusion and exclusion criteria, 57 patients were finally determined as research samples. Samples were selected by utilizing Simple Random Sampling. The number of samples in the case group and control group was amounted to 39 patients, respectively. The data of this research were then analyzed using the Spearman Correlation test.Result: The research results indicated that the least number of decubitus patients at stage I was amounted to 8 people (10.3%), and the highest number of decubitus patients at stage III was amounted to 12 people (15.4%). Furthermore, the results of the Spearman correlation test showed that there was a significant correlation of serum albumin levels and stages of decubitus (p = 0.002).Conclusion: There was a significant correlation of serum albumin levels and stages of decubitus in inpatients at Dr. Soetomo Regional General Hospital of Surabaya in the period of January 2018 – December 2020.Keywords: Albumin, Malnutrition, Stages of Decubitus]]>
<![CDATA[THE RELATIONSHIP OF PAIN LEVEL AND THE QUALITY OF PHYSICAL ACTIVITY IN PATIENTS OF KNEE OSTEOARTHRITIS ]]>
<![CDATA[Elaine Millicent]]>;
<![CDATA[Nunung Nugroho]]>;
<![CDATA[Tabita Novita Anggriani]]>
<![CDATA[ JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 4 (2022): October ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA ]]>
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DOI: 10.33508/jwmj.v4i4.4332
<![CDATA[Background: Osteoarthritis is the most common disease of arthritis that often occurs in the hands, hips, and knees. OA results in degeneration of the joints and causes pain. OA accounts for 7% or approximately 500 million people worldwide in the global population. The prevalence of OA in Indonesia is relatively high, namely 15.5% in men and 12.7% in women. Complaints that are very often complained of by OA patients are pain when doing various daily activities. Pain felt by OA sufferers can affect the quality of physical activity in OA patients.Objective: This study aims to determine the relationship between pain level and the quality of physical activity in patients with osteoarthritis of the knee joint at PHC Surabaya Hospital.Methods: This study used an observational analytic study carried out with a cross-sectional approach. The sampling technique used was non-probability sampling, purposive sampling with respondents who met the inclusion and exclusion criteria. The population used in osteoarthritis sufferers at PHC Surabaya Hospital with 76 respondents. The measuring instrument used to measure pain is the Numerical Rating Scale (NRS), and the questionnaire used to assess the quality of physical activity is the WOMAC questionnaire.Results: The results of this study obtained a p-value 0.000 (p<0.005) and r = 0.922, which indicates that there is a significant relationship between the level of pain and the quality of physical activity in patients with osteoarthritis.Conclusion: there is a relationship between the level of pain and the quality of physical activity in patients with osteoarthritis.]]>
<![CDATA[CORRELATION BETWEEN SOCIAL ACTIVITY LEVEL WITH DEPRESSION IN ELDERLY DURING THE COVID-19 PANDEMIC ]]>
<![CDATA[Vincentia Prasari Setyowardhani]]>;
<![CDATA[Yudita Wulandari]]>;
<![CDATA[Nita Kurniawati]]>
<![CDATA[ JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 4 (2022): October ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA ]]>
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DOI: 10.33508/jwmj.v4i4.3663
<![CDATA[Background: With the COVID-19 pandemic that’s currently happening, the Indonesian government made a policy called Pembatasan Sosial Berskala Besar (PSBB) to prevent the transmission of the COVID-19 virus. As a result of this new policy there was a change in the lives of Indonesians, like restrictions and a decrease in their social activities. The elderly are individuals who experiences a decline in various body function, which causes decreased social activities, and due to the reduction of their social activities, they’re potentially to experience depression due to feeling isolated and lonely. With this PSBB policy, the elderly whose social activities have already decreased, will potentially experience a more and massive reduction in their activities, and because of that the potential for depression will likely to increase.Objective: To determine the correlation between social activity level with depression in elderly during the COVID-19 pandemic.METHOD: The design of this research is observational analysis using a cross sectional method. The data were collected using the Australian Community Participation Questionnaire (ACPQ) and Geriatric Depression Scale (GDS). Statistical analysis test used in this research was Spearman correlation test.RESULTS: Social activities of the elderly in the moderate category were 47.2% and elderly who are not depressed were 81,5%. The results from the Spearman test were found to have a significant correlation between the two variables, p value = < 0.05. The correlation level from the test was -0.335 which indicates a low correlation level.CONCLUSION: There is a significant correlation that has a negative value, so it can be concluded that if social activity level is high, then the incidence of depression is low or non-existent. KEYWORD: Elderly, Social Activity, Depression, COVID-19 pandemic, Pembatasan Sosial Berskala Besar (PSBB).]]>
<![CDATA[CORRELATION DEGREES OF TUMOR INFILTRATING LYMPHOCYTES (TILs) WITH GLEASON SCORE IN PROSTATE ADENOCARCINOMA ]]>
<![CDATA[Mitchell Theny]]>;
<![CDATA[Irene L Parengkuan]]>;
<![CDATA[Paul L Tahalele]]>
<![CDATA[ JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 4 (2022): October ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA ]]>
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DOI: 10.33508/jwmj.v4i4.4338
<![CDATA[Introduction: One of the abnormalities in the prostate gland is prostate adenocarcinoma. Prostate adenocarcinoma expresses tumor antigen in the form of Prostate Specific Antigen (PSA) which will then be recognized by the immune system. The immune system then responds by infiltrating the tumor tissue. Tumor Infiltrating Lymphocytes (TILs) are defined as the infiltration of lymphocytes into the tumor microenvironment. T lymphocytes have a role in recognizing and killing tumor cells. The Gleason grading system together with serum PSA assessment and clinical staging are key in determining appropriate therapy and prognosis in prostate adenocarcinoma. The Gleason grading system is used to assess the degrees of glandular differentiation in prostate adenocarcinoma. An increase in the gleason score indicates poor gland differentiation.Purpose: To assess the correlation between the degrees of Tumor Infiltrating Lymphocytes (TILs) with gleason score in prostate adenocarcinoma.Method: This retrospective study used a correlation analytic method with a cross sectional study design that measured the degrees of Tumor Infiltrating Lymphocytes (TILs) in each gleason score of prostateadenocarcinoma that was observed once at a time. The research samples obtained from the patient's medical records included the gleason score and histopathological slides of the Transurethral Resection of Prostate (TURP) with hematoxylin eosin (HE) staining which were diagnosed as prostate adenocarcinoma according to the inclusion criteria using the non-probability total sampling method at Dr.RamelanNavy’s Central Hospital and analyzed using SPSS version 25 application.Result: Spearman correlation test to assess the correlation between the degree of stromal TILs with gleason score obtained p-value = 0.345 (p >0.05) which indicates there is nocorrelation.Conclusion: There is nocorrelation between high grade stromal TILs and high Gleason Score in prostate adenocarcinoma]]>
<![CDATA[ARTIFICIAL INTELLIGENCE IN DETECTING ATHEROSCLEROSIS PLAQUES AND ELECTROMAGNETIC THERAPY TO ALTER CHOLESTEROL LEVEL ]]>
<![CDATA[Florentina D Pramesuari]]>
<![CDATA[ JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 4 (2022): October ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA ]]>
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DOI: 10.33508/jwmj.v4i4.4334
<![CDATA[Introduction: Artificial Intelligence (AI) application in healthcare fields include matching patient symptoms to appropriate physician, helped to diagnose patients, determine patient’s prognosis, drug discovery, translating languages, and organize data. AI technology used in analysis and diagnosing coronary atherosclerotic plaques has increased annually. There are studies suggested that extremely low-frequency electromagnetic fields exposure can affect lipid metabolism.Purpose: To use applied AI in a device that can both identifying atherosclerosis in blood vessel and treat with low-frequency electromagnetic wave.Method: Experiments carried out using a device to detect and treat blockage of blood vessels by emitting electromagnetic signals. This tool is an AI breakthrough that not only includes a diagnostic function, but can also perform electromagnetic therapy.Result: Previous studies mentioned that AI can be applied to identify atherosclerosis. There are some studies that states low-frequency electromagnetic waves can alter HDL and cholesterol levels in blood. Larger studies are needed to combine both function in identify atherosclerosis plaques and electromagnetic therapy.Conclusion: Rapidly developing AI technology can be applied to identify atherosclerosis plaque and treat them. Further studies are required to provide definitive proof of electromagnetic wave effects on the removal of cholesterol from plaques using thermal effects or raising HDL concentrations in blood.]]>
<![CDATA[THE DIFFERENCES IN RAT CHOLESTEROL LEVELS AFTER GIVING RED GUAVA JUICE ]]>
<![CDATA[Ni MDS Hayati]]>;
<![CDATA[Dewa AL Dewi]]>;
<![CDATA[Chrisdina P Sari]]>
<![CDATA[ JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 4 (2022): October ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA ]]>
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DOI: 10.33508/jwmj.v4i4.4339
<![CDATA[Introduction: Cholesterol is a fat found in our body, it can be dangerous if cholesterol level is increasing. The way to lower cholesterol levels, such as by consuming high-fiber foods for example red guava.Purpose: To determine the difference in total cholesterol levels in rats after giving red guava juice.Method: The research was conducted using 30 Rattus Norvegicus. Rats were divided into three groups, each group consisted of 10 rats. Control group was given 594 chicken feed, first treatment group was given lard and second treatment group was given lard with red guava juice. Before being given treatment, five rats from each group were examined for their total cholesterol and the remaining five rats were given treatment for 14 days before total cholesterol were checked. Examination of total cholesterol by enzymatic colorimetry CHOD-PAP using blood from orbital vein of rats without fasting.Result: There were significant differences in total cholesterol of rats before and after treatment (P<0.05) in each treatment group. In comparison of three groups that had given treatment, significant difference was found (P=0.005). Significant differences were also found in comparison of two groups, between first treatment group and second treatment group (P = 0.004), insignificant results were found in comparison of control group with first treatment group (P = 0.060), and comparison of control group with second treatment group. (P=0.299).Conclusion: There are differences in total cholesterol of rats, total cholesterol of rats in high-fat diet group with guava juice were lower than the high-fat diet group.]]>
<![CDATA[RELATIONSHIP BETWEEN PARITY AND LABOR WITH BABY BLUES EVENTS IN CLINIC YOSTAVAN MEDIKA SIDOARJO ]]>
<![CDATA[Anastasia R Ardianis]]>;
<![CDATA[Maria E Djaputra]]>;
<![CDATA[Venny Tandyono]]>
<![CDATA[ JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 4 (2022): October ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA ]]>
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DOI: 10.33508/jwmj.v4i4.4335
<![CDATA[Introduction: Parity is the number of children born to the mother and able to live outside the womb. Labor is the birth of the fetus and placenta in sufficient number of month. Maternity blues or post partum blues or baby blues is a depressive syndrome that occurs whitin 14 days which is not too long and will disappear over time whitout treatment.Risk factors in the form of labor due to physical exhaustion during the labor process, and bleeding that can affect the activity of the mother after childbirth. The risk factor is parity due to their lack of experience as primiparous mothers and their inability to properly care for their babies, primiparous mother are more likely to experience the baby blues than multiparous mother. Researchers are interested in conducting research on “The Relationship between Parity and Labor with the Incidence of baby blues at the Clinic Yostavan Medika Prambon, Sidoarjo”.Purpose: Knowing the relationship between parity and labor with the incidence of baby blues in Clinic Yostavan Medika sidoarjoMethod: Cross sectional is used in this research and the sampling method was purposive sampling. This study used the EPDS questionnairewith logistic regression analysis techniques.Result: In the univariate analysis using the bivariate logistic regression test, significant results were obtained with a value of 0,011 which means that parity and delivery are related to the incidence of baby blues. Respondents who experienced the baby blues with primipara parity were as many as 57,6%. Respondents with a normal delivery process who experienced the baby blues 56,7%. Based on the multivariate logistic regression analysis test, the results showed no significant p value = 0.460 which means that parity and delivery have no effect on baby blues.Conclusion: There is not relationship between parity and labor with the incidence of baby blues at Clinic Yostavan Medika, Sidoarjo]]>
<![CDATA[COVID-19 THERAPY: COMPARISON EFFECTIVITY BETWEEN REMDESIVIR AND FAVIPIRAVIR ]]>
<![CDATA[Nevan Go]]>;
<![CDATA[Prettysun A Mellow]]>;
<![CDATA[Bernadette D N Dewi]]>
<![CDATA[ JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 4 (2022): October ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA ]]>
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DOI: 10.33508/jwmj.v4i4.4344
<![CDATA[Introduction: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) is the virus that causes Coronavirus Disease 2019 (COVID-19), a disease of global concern(1). Remdesivir and favipiravir are antiviral drugs that are considered COVID19 therapy, as described in Indonesia's 3rd COVID-19 Management Guidelines. They have a similar mechanism, specifically by inhibiting RNA dependent RNA polymerase of the virus (3). Several studies have reported that patients who were treated with these antivirals had a shorter hospital stays (4–6). However, the comparison of efficacy between remdesivir and favipiravir is still unknown.Methods: An observational analytic study was done using a retrospective cohort design. Eighty-eight medical records of COVID-19 patients between January 2021 to August 2021 are collected by consecutive sampling techniques, and this research was carried out at Gotong Royong Hospital Surabaya.Results: Based on the statistical analysis test, there was no clinical improvement difference found, neither patients received remdesivir nor favipiravir based on their clinical manifestations, such as ventilation support and chest X-ray, measured by WHO ordinal scale (p=0,486 ; p>0,05 on the first week and p=0,942 ; p>0,05 on the second week).Conclusions: Improved clinical manifestations were seen in the second week of therapy, either in patients who received remdesivir or favipiravir, but there was no significant effectivity difference between those drugs.]]>
