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INDONESIA
Jurnal Respirologi Indonesia
Published by Perhimpunan Dokter Paru Indonesia
ISSN : 08537704     EISSN : 26203162     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Respirologi Indonesia (JRI) is an online and printed scientific publication of the Indonesian Society of Respirology (ISR). The journal is published thrice-monthly within a year (January, April, July and October). The journal is focused to present original article, article review, and case report in pulmonary and critical care medicine.
Arjuna Subject : -
Articles 381 Documents
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Evaluating CRP and Oxygen Requirements as Predictors of Poor Outcomes in COVID-19 Patients with Bacterial Pneumonia Moulid Hidayat; Rina Lestari; Indana Eva Ajmala; Prima Belia Fathana; Indah Sapta Wardani
Jurnal Respirologi Indonesia Vol 46 No 2 (2026)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v46i2.1198

Abstract

Background: The COVID-19 pandemic has presented significant challenges in the management of bacterial pneumonia co-infections, particularly among elderly populations. These co-infections, most commonly caused by pathogens such as Streptococcus pneumoniae and Staphylococcus aureus, are associated with increased disease severity, higher mortality rate, and poorer outcomes. Data on bacterial co-infections and their impact on patient recovery remain limited, especially in Indonesia. Therefore, this study investigated the associations of age, oxygen supplementation, oxygen saturation, and clinical markers (procalcitonin and CRP) with outcomes in COVID-19 patients with bacterial pneumonia co-infections. Methods: This cross-sectional predictive study utilized secondary data from medical records of COVID-19 patients with bacterial pneumonia co-infection at the Regional General Hospital of West Nusa Tenggara Province and Universitas Mataram Hospital. Consecutive sampling was used to include patients with confirmed COVID-19 and bacterial pneumonia. Bivariate and multivariate analyses were conducted to assess the association between age, oxygen supplementation, procalcitonin levels, CRP levels, and recovery outcomes. Results: The study analyzed data from 77 COVID-19 patients with bacterial pneumonia co-infection. Significant predictors of poor outcomes included elevated C-reactive protein (CRP) levels (>75 mg/L) and high oxygen supplementation (>6 L/min). Patients with elevated CRP had a sixfold higher risk of death, and higher oxygen requirements were strongly associated with increased mortality. Lower oxygen saturation was also linked to worse outcomes. Findings highlight CRP levels and oxygen needs as critical factors in predicting mortality. Elevated CRP and higher oxygen supplementation were significantly associated with death, providing insights into the management of co-infected COVID-19 patients. Conclusion: CRP levels and oxygen requirements are key predictors of poor outcomes in COVID-19 patients with bacterial pneumonia.

Page 39 of 39 | Total Record : 381

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