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Hirowati Ali
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Majalah Kedokteran Andalas
Published by Universitas Andalas
ISSN : 01262092     EISSN : 24425230     DOI : https://doi.org/10.25077
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Majalah Kedokteran Andalas (MKA) (p-ISSN: 0126-2092, e-ISSN: 2442-5230) is a peer-reviewed, open-access national journal published by Faculty of Medicine, Universitas Andalas and is dedicated to publish and disseminate research articles, literature reviews, and case reports, in the field of medicine and health, and other related disciplines
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 14 Documents
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Search results for , issue "Vol 46, No 9 (2024): Supplementary Januari 2024" : 14 Documents clear
Hubungan Healthy Eating Index Dengan Kenaikan Berat Badan Ibu Selama Kehamilan Di Sumatera Barat Hrlfina, Riska
Majalah Kedokteran Andalas Vol 46, No 9 (2024): Supplementary Januari 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i9.p1376-1385.2024

Abstract

AbstractObjective: To determine the association between the healthy eating index of pregnant women and maternal weight gain during pregnancy in West Sumatra.Methods: Research with a cross-sectional design in West Sumatra on 110 pregnant women.This research is an analysis of secondary data from the study "Giving Dadiah on pregnancy and birth outcomes in West Sumatra".The study used data from 24-hour recall of pregnant women in the first trimester, second trimester and third trimester and pregnant women's weight data.Results: The study showed that there was a relationship between the HEI of pregnant women and the increase in maternal weight during pregnancy with p = 0.049 with a value of r = 0.188.Conclusion: There is a relationship between the healthy eating index of pregnant women and the increase in maternal weight during pregnancy.Keywords:  healthy eating index; weight gain; pregnant woman
Evaluasi Biaya Perawatan Intensif Pasien COVID-19 Di RSUP Persahabatan Jakarta: Pendekatan Activity Based Costing Putra, Andika Chandra
Majalah Kedokteran Andalas Vol 46, No 9 (2024): Supplementary Januari 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i9.p1426-1433.2024

Abstract

Facing the COVID-19 pandemic, the healthcare system, especially in Indonesia, encountered significant operational and financial challenges, particularly concerning intensive care costs. RSUP Persahabatan, serving as a national referral center, consistently managed COVID-19 patients ranging from moderate to critical degrees. Recognizing the importance of cost evaluation for efficiency enhancement, this study aimed to meticulously examine the unit cost of intensive care for COVID-19 patients using the Activity Based Costing (ABC) approach. In-depth analysis revealed that the intensive care unit at RSUP Persahabatan comprises 14 supporting activities and offers 61 service products. Both direct and indirect costs for each activity were successfully identified and quantified. Further, when juxtaposed with the INA-CBGs rates set by the 2023 Indonesian Health Minister's Regulation, it became evident that RSUP Persahabatan's ICU achieved remarkable cost efficiency. These findings not only provide invaluable insights for RSUP Persahabatan but also offer strategic recommendations for other healthcare institutions in the evaluation and optimization of COVID-19 intensive care costs. 
Gambaran Efektivitas Transfusi Thrombocyte Concentrate Pada Pasien Immune Thrombocytopenic Purpura di RSUP Dr. M. Djamil Padang Santril, Nitri Ramadhani
Majalah Kedokteran Andalas Vol 46, No 9 (2024): Supplementary Januari 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i9.p1452-1458.2024

Abstract

Latar Belakang: Transfusi trombosit pasien immune thrombocytopenic purpura (ITP) diindikasikan pada kasus ITP dengan perdarahan. Transfusi trombosit pada pasien ITP tidak diikuti dengan peningkatan jumlah trombosit. Corrected count increment (CCI) merupakan penghitungan untuk menilai efektivitas transfusi trombosit. Efektif bila CCI 1 jam pasca transfusi >7,5 x 109/L dan CCI 24 jam >4,5 x 109/L. Tujuan: Mendapatkan gambaran efektivitas transfusi trombosit concentrate (TC) berdasarkan nilai CCI. Metode: Penelitian dilakukan terhadap 31 pasien ITP yang mendapatkan transfusi TC Desember 2022- April 2023. Efektivitas transfusi dinilai berdasarkan nilai CCI 1 jam dan 24 jam pasca transfusi. Hasil: Median jumlah trombosit sebelum transfusi adalah 5,0 x 103/L. Median CCI (Min-Maks) 1 jam 1,88 (0,26-14,5) dan medianCCI 24 jam adalah 2,39 (0,26-15,89). Sebanyak 16,1% sampel efektif berdasarkan nilai CCI 1 jam dan 83,9% tidak efektif. Nilai CCI 24 jam pasca transfusi, 35,5% efektif dan 64,5% tidak efektif. Diskusi: Transfusi TC pada pasien ITP tidak efektif berdasarkan nilai CCI 1 jam dan 24 jam karena pendeknya masa hidup trombosit yang ditransfusikan akibat didestruksi oleh sistem imun. Simpulan: Efektivitas transfusi TC pasien ITP berdasarkan nilai CCI 1 jam pasca transfusi adalah 16,1% pasien dan CCI 24 jam adalah 35,5%. Transfusi trombosit pada ITP perlu indikasi tepat
Adeno-Associated Virus (AAV) Gene Therapy pada Hemofilia: A Systematic Review Angriani, Winda; Afdhal, Fitrah
Majalah Kedokteran Andalas Vol 46, No 9 (2024): Supplementary Januari 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i9.p1459-1470.2024

Abstract

Hemofilia A (HA) dan Hemofilia B (HB) adalah kelainan perdarahan terkait kromosom X yang disebabkan oleh defisiensi faktor koagulasi Faktor VIII (FVIII) atau Faktor IX (FIX). Manifestasi klinis hemofilia, yaitu perdarahan spontan berulang pada otot dan jaringan lunak, serta perdarahan serius lainnya, seperti perdarahan intrakranial, dapat menyebabkan disabilitas seumur hidup hingga kematian. Pasien hemofilia mendapat terapi standar infus konsentrat FVIII atau FIX untuk meningkatkan hemostasis yang diberikan sebagai respons terhadap perdarahan atau profilaksis untuk mencegah perdarahan, namun terapi ini tidak cost-effective dan effisien. Terapi gen menawarkan potensi penyembuhan melalui produksi FVIII atau FIX endogen. Penelitian ini bertujuan membahas efektivitas terapi gen Adeno-Associated Virus (AAV) sebagai terapi hemofilia. Metode: Penulisan artikel ini menggunakan metode systematic review. Pencarian sumber artikel menggunakan bantuan mesin pencari PubMed. Hasil: Penelitian ini menggambarkan bahwa terapi gen dengan menggunakan vektor Adeno-Associated Virus (AAV) cukup menjanjikan dalam pengobatan hemofilia. Dari penelitian yang kami tinjau, terlihat bahwa terapi ini berhasil meningkatkan tingkat faktor pembekuan yang hilang, mengurangi insiden perdarahan tahunan, bahkan memungkinkan pasien untuk menghentikan penggunaan profilaksis. Kesimpulan: Temuan ini menegaskan bahwa terapi gen AAV memiliki potensi besar untuk menjadi solusi efektif dan berkelanjutan dalam mengelola hemofilia, dengan dampak positif yang signifikan terhadap kualitas hidup pasien hemofilia.

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