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INDONESIA
ISM (Intisari Sains Medis) : Jurnal Kedokteran
Published by Universitas Udayana
ISSN : 25033638     EISSN : -     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.
Arjuna Subject : -
Articles 1,063 Documents
 68   69   70   71   72 
Glaukoma sekunder pada pasien anak dengan Sindrom Sturge Weber: laporan kasus Putu Dian Megasafitri; I Gusti Ayu Ratna Suryaningrum; I Made Agus Kusumadjaja
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (775.584 KB) | DOI: 10.15562/ism.v12i1.859

Abstract

Background: Sturge Weber's Syndrome (SSW) is a rare congenital disorder characterized by hemangiomas found in several parts of the body, such as the ocular, intracranial, and facial skin structures. Patients with SSW often experience glaucoma as one of the frequent ocular manifestations which can occur from birth or throughout life and can cause blindness. This case report aims to report the management of a pediatric patient with SSW who underwent trabeculectomy after failing to maintain intraocular pressure with topical drugs.Case Presentation: A 5-year-old girl had increased intraocular pressure and optic nerve glaucoma signs in her right eye. This patient also had a birthmark in the form of a port-wine stain on her face's right side. After undergoing several tests, the patient was diagnosed with secondary glaucoma due to SSW with poor intraocular pressure control after 1.5 years of topical selective beta-blocker treatment. Trabeculectomy + 5-fluorouracil (5-FU) is performed to reduce intraocular pressure and prevent worsening of glaucoma. On the first day after surgery, the intraocular pressure was 20 mmHg in the right eye and decreased significantly during follow-up.Conclusion: Trabeculectomy is one of the treatment options to treat glaucoma in SSW patients, which results in reasonable control of intraocular pressure.  Latar Belakang: Sindrom Sturge Weber (SSW) adalah kelainan bawaan yang jarang terjadi dimana ditandai dengan adanya hemangioma yang terdapat pada beberapa bagian tubuh, seperti struktur kulit okuler, intrakranial, dan wajah. Pasien dengan SSW sering mengalami glaukoma sebagai salah satu manifestasi okuler yang sering terjadi dimana dapat muncul sejak lahir maupun sepanjang masa kehidupannya serta dapat menyebabkan kebutaan. Laporan kasus ini bertujuan untuk melaporkan penatalaksanaan pada pasien anak dengan SSW yang menjalani prosedur trabekulektomi setelah gagal mempertahankan tekanan intraokuler dengan obat topikal.Presentasi Kasus: Seorang anak perempuan berusia 5 tahun mengalami peningkatan tekanan intraokuler dan tanda-tanda saraf optik glaukoma di mata kanannya. Pasien ini juga memiliki tanda lahir berupa port wine stain di bagian kanan wajahnya. Setelah menjalani beberapa pemeriksaan, pasien terdiagnosa menderita glaukoma sekunder oleh karena SSW dengan kontrol tekanan intraokuler yang buruk setelah 1,5 tahun menjalani pengobatan topikal golongan beta bloker selektif. Operasi trabekulektomi + 5-fluorouracil (5-FU)dilakukan untuk menurunkan tekanan intraokuler dan mencegah perburukan glaukoma. Pada hari pertama setelah operasi, tekanan intraokuler menjadi 20 mmHg pada mata kanan dan berkurang secara bermakna selama masa tindak lanjut.Kesimpulan: Trabekulektomi merupakan salah satu pengobatan pilihan untuk mengobati glaukoma pada pasien SSW yang menghasilkan kontrol tekanan intraokuler yang baik.
Anemia defisiensi besi pada pasien dengan ulkus peptikum: Laporan kasus I Dewa Agung Gede Agastya Janardhana; I Dewa Gede Agung Suta Ariwangsa
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (392.246 KB) | DOI: 10.15562/ism.v12i1.860

Abstract

Background: Anemia is a decrease in hemoglobin levels from the standard limit that can be caused by iron deficiency and chronic bleeding. One-third (32.9%) of the world population is estimated to suffer from anemia, and iron deficiency is a common cause of anemia in all countries. The diagnosis is made through history taking, physical examination and investigations.Case report: 59-year-old male patient with complaints of black stool, abdominal pain and weakness. On physical examination, found pale conjunctiva, angular stomatitis and atrophy of the tongue. On complete blood, the examination found a decrease in erythrocyte levels, hemoglobin, MCV, MCH, and MCHC and increased RDW-CV. Analysis of peripheral blood smears presents with hypochromic microcytic poikilocytosis anemia, serum iron is decreased, and increased TIBC. Chronic bleeding anemia accompanied by iron deficiency will cause ferritin levels to decrease or be normal to 60 µg / dl. The patient was diagnosed with peptic ulcers as seen from esophagoduodenoscopy and severe anemia caused by iron deficit and chronic bleeding. Patients were treated supportively with PRC transfusion, ferrous sulfate and vitamin C.Conclusion: The patient’s iron deficiency anemia resulted from peptic ulcers, which caused chronic bleeding.  Latar belakang: Anemia merupakan kondisi dengan kadar hemoglobin yang lebih rendah dari nilai normal. Anemia dapat disebabkan akibat defisiensi besi atau perdarahan kronis. Sebesar sepertiga (32,9%) populasi didunia diperkirakan menderita anemia. Defisiensi besi merupakan penyebab umum anemia di seluruh negara. Penegakan diagnosis anemia dilakukan melalui anamnesis, pemerikaan fisik, dan pemeriksaan penunjang.Laporan kasus: Pasien laki-laki 59 tahun dengan keluhan BAB hitam, nyeri perut dan lemas. Pada pemeriksaan fisik ditemukan konjungtiva anemis, stomatitis angularis dan atrofi papil lidah. Pada pemeriksaan darah lengkap ditemukan penurunan kadar eritrosit, Hemoglobin, MCV, MCH, dan MCHC, peningkatan RDW-CV. Pemeriksaan apusan darah tepi gambaran anemia bikromik mikrositer poikilositosis, serum besi menurun, dan peningkatan TIBC. Anemia perdarahan kronis disertai defisiensi besi akan menimbulkan kadar ferritin menurun atau normal hingga 60µg/dl. Pasien didiagnosis dengan ulkus peptikum dilihat dari hasil Esofagoduodenoskopi dan anemia berat yang disebabkan oleh defisensi besi dan perdarahan kronis.  Pasien diterapi suportif dengan Tranfusi PRC, pemberian ferrous sulphate dan vitamin C.Kesimpulan: Anemia defisiensi besi pada pasien ditimbulkan oleh ulkus peptikum yang menyebabkan terjadinya perdarahan kronis. 
Nilai diagnostik dari mean platelet volume (MPV) pada sepsis neonatorum di RSUD Wangaya, Denpasar, Bali, Indonesia Jeven Reggie Santoso; I Wayan Bikin Suryawan; Made Ratna Dewi
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (361.06 KB) | DOI: 10.15562/ism.v12i1.862

Abstract

Background: Neonatal sepsis is a clinical syndrome of systemic disease with high morbidity and mortality. Early diagnosis of neonatal sepsis is still difficult to be done. A cheap, fast, and accurate septic marker is needed. Several studies of mean platelet volume have been done and are considered as one of the markers that can help diagnose neonatal sepsis early and accurately. The objective of this study is to assess the diagnostic value of MPV in neonatal sepsis.Methods: This analytic observational study with the diagnostic test was done by collecting secondary data from medical records of neonates with suspicion of neonatal sepsis in Wangaya Hospital, Denpasar, from January 2019 to June 2020.  MPV cut-off point was determined with receiver-operating characteristic (ROC) curve. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of MPV in neonatal sepsis were determined using a 2x2 table.Results: Of 104 sample subjects, 16 subjects (15.4%) were diagnosed with neonatal sepsis. MPV with a cut-off point of 9.95 fl had 62.5% sensitivity, 61.4% specificity, 22% PPV, 90% NPV, and 61% accuracy.Conclusion: MPV with a cut-off point of 9.95 fl can be used to diagnose neonatal sepsis with a 62.5% sensitivity and a 61.4% specificity.  Latar Belakang: Sepsis neonatorum merupakan sindrom klinik penyakit sistemik yang memiliki angka morbiditas dan mortalitas yang tinggi pada neonatus. Diagnosis sepsis neonatorum masih sulit dilakukan dengan cepat. Diperlukannya alat penanda sepsis yang murah, cepat, dan akurat. Beberapa penelitian mengenai mean platelet volume (MPV) telah dilakukan dan salah satu pilihan pemeriksaan yang diharapkan dapat membantu penegakan diagnosis sepsis neonatorum dengan cepat dan akurat. Tujuan penelitian ini adalah untuk mengetahui nilai diagnostik dari MPV pada sepsis neonatorum.Metode: Studi observasional analitik dengan uji diagnostik ini dilakukan dengan mengumpulkan data sekunder dari rekam medis neonatus yang dirawat di RSUD Wangaya, Denpasar dengan kecurigaan sepsis neonatorum dari Januari 2019 hingga Juni 2020. Titik potong nilai MPV akan ditentukan menggunakan kurva receiver-operating characteristic (ROC). Nilai sensitivitas, spesifisitas, nilai duga positif (NDP), nilai duga negatif (NDN), dan akurasi dari nilai MPV pada sepsis neonatorum akan ditentukan menggunakan tabel 2x2.Hasil: Dari 104 subjek sampel, didapatkan subjek dengan diagnosis sepsis neonatorum sebesar 16 subjek (15.4%). Dengan titik potong MPV sebesar 9,95 fl, didapatkan nilai sensitifitas 62,5%, spesifisitas 61,4%, NDP 22%, NDN 90%, dan akurasi 61%.Kesimpulan: MPV dengan titik potong 9,95 fl dapat mendiagnosis sepsis neonatorum dengan sensitifitas 62,5% dan spesifisitas 61,4%.
Patogenesis dan diagnosis immune reconstitution inflammatory syndrome tuberculosis Gede Wira Mahadita; I Ketut Agus Somia
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1238.345 KB) | DOI: 10.15562/ism.v11i3.863

Abstract

Progressive increase in the incidence of tuberculosis (TB) and its coinfection with human immunodeficiency virus (HIV) is observed. Immune system restoration related to highly active antiretroviral therapy (HAART) can cause an immunopathologic reaction termed immune reconstitution inflammatory syndrome (IRIS)-TB. Many aspects of the IRIS phenomenon remain unraveled since its first discovery in 1954. This review is intended to summarize available evidence on various aspects of IRIS with particular focus on its pathogenesis and diagnosis. Insiden tuberkulosis (TB) dan koinfeksinya dengan infeksi human immunodeficiency virus (HIV) terus meningkat dari tahun ke tahun. Perbaikan imunitas yang berhubungan dengan highly active antiretroviral therapy (HAART) dapat disertai dengan reaksi imunopatologis yang disebut sebagai immune reconstitution inflammatory syndrome (IRIS)-TB. Perkembangan pengetahuan mengenai IRIS sejak fenomena ini pertama kali ditemukan pada tahun 1954 masih belum sempurna. Tinjauan ini bertujuan untuk merangkum literatur yang tersedia mengenai beragam aspek IRIS dengan fokus pada aspek patogenesis dan diagnosis.
Epidemiologi pasien luka bakar di RSUP Sanglah Denpasar tahun 2018-2019 Ni Kadek Ayunda Sarini Dewi; I Made Suka Adnyana; I Gusti Putu Hendra Sanjaya; Agus Roy Rusly Hariantana Hamid
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (259.296 KB) | DOI: 10.15562/ism.v12i1.865

Abstract

Background: Burns are loss of tissue or a form of tissue damage that occurs as a result of contact with heat sources such as fire, chemicals, hot water, electricity, and radiation which are a type of trauma with high morbidity and mortality so that they require special treatment from the initial phase to advanced phase. This study aims to find out, comprehend, and describe the epidemiology of burn patients' causes and mortality at the Sanglah General Hospital in 2018-2019.Methods: The research was conducted with a descriptive method using cross-sectional studies. Samples were selected from the population-based on inclusion and exclusion criteria. Data were analyzed using SPSS version 24 software to obtain the epidemiology of the causes, length of stay, and burns mortality.Results: The results showed that the highest cause of burns was caused by fire, namely 65 people (53.3%). In the adult group, most burns were caused by fire, namely 55 people (45.1%), while in the group of children, most burns were caused by objects / hot water, namely 14 people (11.5%). The mortality of burnt sufferers was 11 people (9%) out of 122 people (100%), where all deaths occurred in the adult group. An IIAB degree burns were the highest burns with the highest mortality with 10 people (90.9%). Most of the burn injuries caused by fire burns were 7 people (63.6%) and the highest case was second-degree burns caused by fire, namely 60 people (56.1%).Conclusion: The results showed that the most common burns were caused by a fire in the adult group and objects/hot water in the children group. IIAB degree burns are the highest degree of burns with mortality.Latar Belakang: Luka bakar adalah kehilangan jaringan atau suatu bentuk kerusakan jaringan yang terjadi akibat dari kontak dengan sumber panas seperti api, bahan kimia, air panas, listrik dan radiasi yang merupakan jenis trauma dengan morbiditas dan mortalitas yang tinggi sehingga memerlukan perawatan yang khusus mulai fase awal hingga fase lanjut. Penelitian ini bertujuan untuk mengetahui, memahami dan mendeskripsikan epidemiologi penyebab dan mortalitas pasien luka bakar di Rumah Sakit Umum Pusat Sanglah Denpasar tahun 2018-2019.Metode: Penelitian dilakukan dengan metode deskriptif menggunakan studi potong lintang. Sampel dipilih dari populasi berdasarkan kriteria inklusi dan eksklusi. Data dianalisis menggunakan software SPSS versi 24 untuk mendapatkan epidemiologi penyebab dan mortalitas luka bakar.Hasil: Hasil penelitian menunjukkan bahwa epidemiologi penyebab luka bakar tertinggi disebabkan oleh api yaitu 65 orang (53,3%).  Pada kelompok dewasa, pasien luka bakar terbanyak disebabkan oleh api yaitu 55 orang (45,1%), sedangkan pada kelompok anak-anak luka bakar terbanyak disebabkan oleh benda/air panas yaitu 14 orang (11,5%). Mortalitas pasien luka bakar yaitu 11 orang (9%) dari 122 orang (100%), dimana semua kematian terjadi pada kelompok dewasa. Luka bakar derajat IIAB merupakan derajat luka bakar dengan kematian tertinggi yaitu 10 orang (90,9%). Kematian luka bakar terbanyak disebabkan oleh luka bakar akibat api sebanya 7 orang (63,6%) dan kasus tertinggi adalah luka bakar derajat IIAB yang disebabkan oleh api yaitu 60 orang (56,1 %).Kesimpulan: Hasil penelitian ini menunjukkan bahwa luka bakar tersering disebabkan oleh api pada kelompok dewasa dan benda/air panas pada kelompok anak-anak. Luka bakar derajat IIAB merupakan derajat luka bakar dengan kematian tertinggi. 
The association between overweight and shock in children with dengue hemorrhagic fever at Wangaya General Hospital, Bali, Indonesia Jade Irene Linardi; I Wayan Bikin Suryawan; Anak Agung Made Widiasa
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (243.517 KB) | DOI: 10.15562/ism.v%vi%i.868

Abstract

Background: Dengue Hemorrhagic Fever (DHF) which severity varies, has devastating complications and outcomes, especially when shock events appeared and are prolonged. There is no predictor of whether DHF patients would develop into shock (called Dengue Shock Syndrome or DSS). Previous studies claimed overweight as a predictor of DSS, although it remains controversial.Objective: To find the association between overweight and shock events in children with DHF.Methods: This was an observational analytic study with a case-control design. Data were taken from medical records with children hospitalized at Wangaya General Hospital from May 2019 through April 2020. Inclusion criteria were children < 18 years who have been diagnosed with DHF grade I through IV. Data were analyzed using the chi-square test in SPSS 24.0 for windows.Results: Of 126 subjects who fulfilled the inclusion criteria, there were 42 DSS patients as the case group and 84 non-DSS patients as the control group. From the data analysis, there was a significant association between overweight and shock events in children with DHF (p=0.001; OR 3.76; 95% CI 1.72 to 8.20). Furthermore, pleural effusion (p=0.001), highest hematocrit of ? 46% (p=0.001), and lowest platelet count of ? 50,000/µL (p=0.006) also had significant association with shock events.Conclusion: Overweight is associated with shock events in children with DHF. Pleural effusion, hematocrit level of ? 46%, and platelet count of ? 50,000/µL were also counted as risk factors to develop shock.
Kondiloma akuminata perianal pada seorang laki-laki biseksual disertai infeksi HIV stadium III yang diterapi dengan kombinasi asam trikloroasetat 80% dan seng oral Rahel Lisana Debora Hutagalung; Anak Agung Gde Putra Wiraguna
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (547.013 KB) | DOI: 10.15562/ism.v12i1.869

Abstract

Background: Condyloma acuminata in the homosexual population caused by anogenital sexual behavior causes more microabrasion to occur which increases the risk of infection with human papilloma virus (HPV) and HIV. This case report aims to provide an overview of the clinical outcome of condyloma acuminata in homosexual patients with HIV grade III.Case: Male, 26 years old with an itchy and painless lump around the genitals and anal canal since two months ago. The new patient was diagnosed with HIV since two weeks before the visit to the Sanglah Hospital polyclinic. It was found that the patient was a homosexual with a history of multiple partners and had been going on for five years. Physical examination of the perianal region revealed multiple skin-colored tumors, geographic shape, 3x5cm - 3x5.5cm in size, with a verrucous surface, and solid consistency with a positive acetowhite test that concluded as perianal condyloma acuminata. It was decided to give tricolor acetate (TCA) 80% spotted therapy and oral zinc sulfate 100mg/day. Up to 2 TCA session therapy and oral zinc administration in approximately three weeks, the lesion was getting better with efflorescence in the form of multiple papules, color of the mucosa that confluent to form a tumor, geographic shape, size 3x2cm - 3x3cm, smooth surface, solid consistency.Conclusion: The response to treatment with TCA 80% for 2 times and oral zinc for 3 weeks was quite good, the number of lesions was reduced and the size of the lesions was reduced. The prognosis of the patient is dubious because even if the condyloma acuminata lesion has been repaired, the presence of HIV infection can lead to the risk of recurrence and the risk of progression to malignancy. Latar belakang: Kondiloma akuminata pada populasi homoseksual diakibatkan oleh perilaku seksual secara anogenital menyebabkan lebih banyak mikroabrasi yang terjadi yang menyebabkan peningkatan risiko infeksi human papilloma virus (HPV) dan HIV. Laporan kasus ini bertujuan untuk memberikan suatu gambaran luaran klinis dari kondiloma akuminata pada pasien homoseksual dengan HIV derajat III.Kasus: Laki-laki, 26 tahun dengan benjolan risakan gatal dan tidak nyeri pada sekitar kelamin dan lubang anus sejak dua bulan yang lalu. Pasien baru terdiagnosa HIV sejak dua minggu sebelum kunjungan poliklinik RSUP Sanglah. Diketahui pasien merupakan seorang homoseksual dengan riwayat berganti-ganti pasangan dan sudah berlangsung selama lima tahun. Pemeriksaan fisik region perianal menunjukkan tumor sewarna kulit multipel, bentuk geografika, ukuran 3x5cm – 3x5,5cm, dengan permukaan verukosa, dan konsistensi padat dengan hasil tes acetowhite positif yang disimpulkan sebagai suatu kondiloma akuminata perianal. Diputuskan untuk memberikan terapi tutul tricolor acetat 80% dan seng sulfat oral 100mg/hari. Hingga terapi 2 kali tutul dan pemeberian seng oral dalam jangka waktu kurang lebih tiga minggu terjadi perbaikan lesi dengan efloresensi berupa papul multipel sewarna mukosa yang berkonfluen membentuk tumor, bentuk geografika, ukuran 3x2cm – 3x3cm, permukaan licin, konsistensi padat.Simpulan: Respon pengobatan dengan TCA 80% selama 2 kali dan seng oral selama 3 minggu cukup baik, jumlah lesi berkurang dan ukuran lesi mengecil. Prognosis dari pasien adalah dubius karena walaupun telah terjadi perbaikan lesi kondiloma akuminata, adanya infeksi HIV dapat menyebabkan risiko terjadinya rekurensi dan risiko perkembangan ke arah keganasan.
Hubungan berat badan lahir rendah dengan asfiksia neonatorum di Rumah Sakit Umum (RSU) Negara Made Dwitia Ayu Iswari; I Gusti Ketut Winata Adnyana
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.113 KB) | DOI: 10.15562/ism.v11i3.871

Abstract

Background: low birth weight is one of the mortality causes in neonates. This condition is associated with organ immaturity including lung and inadequate surfactant in alveolus which increase the risk of asphyxia neonatorum.The aim of this study is to know the correlation between low birth weight and asphyxia neonatorum in RSU Negara.Methods: The design of this study was observational analytic cross-sectional. Neonates, who were hospitalized in NICU and perinatology RSU Negara, Jembrana in August 2019-August 2020 were assigned by systematic random sampling. Data was collected from medical records. Then, data was analyzed using chi-square test and logistic regression test to get prevalence ratio (PR). The value of p<0.05 was considered significant.Result: As many as 150 neonates were recruited in the study. A multivariate analysis showed the prevalence of asphyxia neonatorum was significantly higher in low birth weight neonates (PR=2.331, p=0.045; IK 95% 1.018-5.338) than non-low birth weight neonates. There were no association between asphyxia neonatorum and prematurity, mode of delivery and sex of newborn.Conclusion: low birth weight is associated with asphyxia neonatorum.  Latar Belakang: Berat badan lahir rendah merupakan salah satu penyebab kematian neonatus. Kondisi ini disertai dengan imaturitas organ tubuh termasuk paru-paru dan kurangnya surfaktan dalam alveolus sehingga meningkatkan risiko terjadinya asfiksia neonatorum. Tujuan penelitian ini adalah untuk mengetahui hubungan antara berat badan lahir rendah dan asfiksia neonatorum di RSU Negara.Metode: penelitian ini menggunakan rancangan analitik observasional potong-lintang. Neonatus yang dirawat di Bagian NICU dan perinatologi RSU Negara, Jembrana dalam kurun waktu Agustus 2019 – Agustus 2020 yang dikumpulkan secara systematic random sampling. Data dikumpulkan dari rekam medis. Data kemudian dianalisis secara bivariat dengan uji chi-square dan multivariat dengan uji regresi logistik sehingga diperoleh prevalence ratio (PR). Hubungan dikatakan signifikan apabila diperoleh nilai p< 0,05.Hasil: penelitian ini mengikutsertakan sebanyak 150 neonatus. Berdasarkan hasil uji multivariat, prevalensi kejadian asfiksia neonatorum lebih tinggi pada neonatus dengan BBLR (PR=2,331, p=0,045; IK 95% 1,018-5,338) dibandingkan dengan yang tidak mengalami BBLR. Tidak ada perbedaan kejadian asfiksia berdasarkan prematuritas, cara persalinan, dan jenis kelamin bayi.Simpulan: berat badan lahir rendah berhubungan dengan asfiksia neonatorum
Clinical profile of steroid-induced glaucoma in Bali Mandara Eye Hospital year 2019 Ni Kompyang Rahayu; Ardelia Emily
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (313.125 KB) | DOI: 10.15562/ism.v12i1.872

Abstract

Introduction: Glaucoma is an optic neuropathy characterized by optic disc cupping and visual field loss usually associated with raised intraocular pressure. Glaucoma incidence is rapidly increasing, with global incidence is estimated to reach 76 million in 2020. There are many causes of glaucoma; one of them is corticosteroid use. Unmonitored steroid use can be resulting in undesirable side effects such as steroid-induced glaucoma. This study aims to evaluate the clinical profile of steroid-induced glaucoma in Bali Mandara Hospital year 2019.Method: A descriptive-cross sectional study was conducted using secondary data involving 35 medical records of patients diagnosed with glaucoma in Bali Mandara Eye Hospital, Denpasar, from January to December 2019. Age, gender, steroid type, routes and duration of steroid administration were recorded from medical records. Obtained data were analyzed descriptively using SPSS version 23 for Windows.   Results: Patient’s characteristics mostly were male 57.14% and 42.86% female, 31.43% were elderly >55 years old. They mostly used eye drops steroid (85.71%), and 14.29% took oral steroids. The most used eye drops were Dexamethasone eye drops (77.14%). For oral steroids, they took Methylprednisolone (8.57%) and Dexamethasone (5.71%). Most of them have symptoms after one year of steroid use (34.39%). Conclusion: Steroid-induced glaucoma can occur in both males or females in all age groups, which the elderly and children have a higher risk. Most cases occur from topical steroids. Steroid-induced glaucoma is avoidable irreversible blindness. Therefore, the use of steroids must be judicious; self-medication must be avoided. The doctor must provide education to patients who are given steroid therapy.
Telerehabilitation as a physical therapy solution for post-stroke patient in COVID-19 pandemic situations: a review I Made Yoga Prabawa; Dedi Silakarma; M. Widnyana
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (456.411 KB) | DOI: 10.15562/ism.v12i1.873

Abstract

Background: Stroke is one of the leading causes of disability among the adult population. One-third of post-stroke patients require ongoing physical rehabilitation to improve their motoric function. But in this COVID-19 pandemic situation, all outpatient visits or non-emergency cases, including in-clinic physical rehabilitation therapy, have been postponed and limited to maintain physical distancing to prevent the spreading of infection. Telerehabilitation can be the answer to overcome this circumstance.Methods: We conducted a comprehensive search for online literature or studies in 2020. We explored evidence using the following database Cochrane Library, PubMed, and Google Scholar. The keywords used to obtain the relevant research include “telerehabilitation” OR “telemedicine” AND “physical rehabilitation” AND “stroke patient” AND “COVID-19 pandemic”. The literature was analyzed based on the results of previous studies.Results: Telerehabilitation delivers rehabilitation services via communication technologies involving the patient and the physical therapist communicate using telehealth platform and video-teleconference. Several telerehabilitation techniques can be used for stroke patients' physical exercise, such as portable transcutaneous electrical stimulation (TENS), mirror therapy, home exercise program, and virtual reality exercise. Several studies have shown that telerehabilitation is not inferior than in-clinic physical exercise, and both showed significant improvement in post-stroke patients' motor function.Conclusions: Telerehabilitation can be the solution for post-stroke patient’s physical rehabilitation in the COVID-19 pandemic. This novel health innovation allowed the post-stroke patient to exercise at home and prevent them from the risk of COVID-19 infection.

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