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Jurnal Respirasi (JR)

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Published by Universitas Airlangga

ISSN : 24070831 EISSN : 26218372 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology Public Health

Jurnal Respirasi is a National journal in accreditation process managed by Department of Pulmonology & Respiratory Medicine Faculty of Medicine Airlangga University - Dr. Soetomo General Hospital, Surabaya. Publish every January, May, September every year with each of 5 (five) complete texts in Indonesian.

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Articles 7 Documents

Search results for , issue "Vol. 4 No. 1 (2018): Januari 2018" : 7 Documents clear

Profil Status Gizi Penderita Tuberkulosis Paru-Multi Drug Resistance dengan Diabetes Mellitus Tipe 2 di RSUD Dr. Soetomo Surabaya Tahun 2016 : [Nutritional Status of Multidrug-Resistant Tuberculosis Patient with Diabetes Mellitus Type 2 in Dr. Soetomo General Hospital Surabaya] Mega Rizkya Arfiana; Tutik Kusmiati; Jongky Hendro Prayitno
Jurnal Respirasi Vol. 4 No. 1 (2018): Januari 2018
Publisher : Faculty of Medicine Universitas Airlangga

Background: Indonesia is the third highest country of Tuberculosis (TB) prevalence world wide. Beside resistances, factor that being a burden for control TB is comorbidities, such as Diabetes Mellitus Type 2 (DMT2). This research aimed to determine the Nutritional Status of Multi Drug Resistance Tuberculosis (MDR-TB) with DMT2 Patients. Methods: This is a descriptive retrospective study observing Nutritional Status of MDR-TB with DMT2 patients based on gender, age, weight, height, and Fasting Blood Glucose (FBG) registered since January,1st –December, 31th 2016 in RSUD Dr. Soetomo Surabaya. Results: Out of 42 Samples, there are 20 mens and 22 womens suffer MDR-TB with DMT2. The Nutritional Status of Women is Normal (28.57 %) and Man is Underweight (16.6 %). Based on the age of patients, 51-60 years is the highest frequency. The mean of Body Mass Index (BMI) from all age categories are Normal, except 31-40 years. The mean of height is 159.95 cm and weight is 52.88 kg. In FBG’s category, 100-200 is the highest frequency and mostly has normal BMI. The mean of BMI is 20.51 kg/m2. Conclusion; Majority patients of MDR-TB with DMT2 has Normal BMI.

Front Matter Vol 4 No 1, 2018 Front Matter
Jurnal Respirasi Vol. 4 No. 1 (2018): Januari 2018
Publisher : Faculty of Medicine Universitas Airlangga

Pemphigus Paraneoplastik pada Timoma : [Pemphigus Paraneoplastic in Thymoma: A Rare Case] Herley Windo Setiawan; Daniel Maranatha
Jurnal Respirasi Vol. 4 No. 1 (2018): Januari 2018
Publisher : Faculty of Medicine Universitas Airlangga

Thymomas are mediastinal primary tumour of the mediastinum and associated with a variety of autoimmune disorders often linked to T-cell mediated autoimmunity. Paraneoplastic pemphigus (PNP) is an immunologically mediated skin disease characterized by epidermal blisters that may occur in association with thymic or non thymic neoplasms. Case: 21 years old man came to the hospital with vesicles and ulcer in oral cavity and extended to whole body since 3 weeks before. Patient was diagnosed with Pemphigus vulgaris and thymomas since 2 years. Patient was hospitalized for 3 times with same cases. Patient underwent chemotherapy Carboplatin-Etoposide 6 series and Radiotherapy 25 series and no response had been documented. Patient was suggested to undergo a resection of thymoma to prevent the exacerbation of pemphigus but he refused. The medication given was only aimed for reducing the exacerbation of Pemphigus. Discussion: PNP is characterized by the production of autoantibodies against various target antigens, mainly plakin family proteins and desmogleins. PNP results from an antitumor immune response cross-reacting with the normal epithelial proteins and thereby inducing autoimmunity by molecular mimicry. PNP sera bind to homologous region within carboxyterminus of members of the plakin gene family. There are also involvement of dysregulation of T-cell development. Conclusion: Pemphigus is rarely associated with Thymomas, but the fact there is an association between Thymomas and pemphigus. According to this fact, every patients with pemphigus should be suspected with malignancies especially thymomas until it was ruled out.

Back Matter Vol 4 No 1, 2018 Back Matter
Jurnal Respirasi Vol. 4 No. 1 (2018): Januari 2018
Publisher : Faculty of Medicine Universitas Airlangga

Seorang Wanita Muda dengan Tuberkulosis Usus Menyerupai Apendiksitis Akut : [Pemphigus Paraneoplastic in Thymoma: A Rare Case] Kadek Widianiti; Tutik Kusmiati; Ida Bagus Ngurah Rai
Jurnal Respirasi Vol. 4 No. 1 (2018): Januari 2018
Publisher : Faculty of Medicine Universitas Airlangga

Background: Tuberculosis has become a global health problem, with increasing numbers of cases in line with the increasing number of immunocompromised patients. Intestinal of tuberculosis is believed to be a form of extrapulmonary tuberculosis which will occur most often in the future . Case: This case presents a young woman, 20 years old, suspected of acute appendicitis with suspected perforation, had right abdominal pain since 1 month and getting worse since 5 days PTA (prior to admission). The abdomen enlarges and feels hard on the right abdomen after being treated for 3 days. Fever,body weaknes,decreased of appetite, decreased of body weight approximately 7 kg since 2 months PTA. There are nausea, vomiting, diarea with runny mucus since 2 weeks PTA. The chest x-ray, abdominal ultrasound, endoscopy was normal result and plain abdominal radiograph showed that intestinal dilatation and step ladder features suspicious obstructive ileus. Discussion: After 2 months of therapy abdominal symptoms improved and weight began to gradually increase. Intestinal of tuberculosis is a challenge for clinicians to diagnose despite using modern medical techniques because the clinical and laboratory features are not specific especially when active pulmonary infection is absent and there are similarities with other abdominal diseases. The histological features will provide a diagnose. The delay in diagnosis will lead to more severe complications. Conclusion: At present a combination of clinical, radiological and pathological features continues to be the key to diagnosing intestinal tuberculosis. Medical management with antituberculosis drugs will produce a significant resolution of symptoms.

Imunopatogenesis Penyakit Paru Obstruktif Kronik : [Immunopathogenesis Update of COPD] Resti Yudhawati; Yuyus Dwi Prasetiyo
Jurnal Respirasi Vol. 4 No. 1 (2018): Januari 2018
Publisher : Faculty of Medicine Universitas Airlangga

Chronic Obstructive Pulmonary Disease (COPD) is an inflammatory airway disease and complicated lung tissue. The airways of patients with COPD contain many inflammatory cells including neutrophils, macrophages, CD8 T lymphocytes, CD4 T lymphocytes and dendritic cells, each of which has its own role and interacts with COPD immunopathogenesis. The inflammatory response in people with COPD involves innate immunity (neutrophils, macrophages, eosinophils, mast cells, natural killer cells, and dendritic cells) and adaptive immunity (T and B lymphocytes), but there is also activation of structual cells such as alveolar epithelial cells endothelial cells and fibroblasts. Inflammation of the respiratory tract in COPD will persist even after quitting smoking, this can be caused by damage to the extracellular matrix will release proinflammatory cytokines which are neutrophil and monocyte chemotaxis, impaired alveolar macrophages which result in impaired cleaning of apoptotic cells and pathogenic microbes and oxidative stress will cause DNA double chain damage.

Empiema: [Empyema: An Update Approach] Helmia Hasan; Devi Ambarwati
Jurnal Respirasi Vol. 4 No. 1 (2018): Januari 2018
Publisher : Faculty of Medicine Universitas Airlangga

Empyema is a collection of exudative fluid in the pleural cavity associated with the occurrence of pulmonary infection. Empyema is often caused by complications of pneumonia but can also be caused by infection from elsewhere. Community-aquired pneumonia has an incidence of 8 to 15 per 1000 per year. Forty to 57% of patients with pneumonia, may develop into a parapneumonic effusion. Approximately 5 to 10% of parapneumonic effusions develop into empyema. All patients with parapneumonia and empyema effusions require antibiotic therapy early and adequate. Sterile pleural effusions with PH ≥ 7,20 were observed and protected by adequate antibiotics. Empyema and localized pleural effusions and parapneumonic effusions with PH <7.20 or glucose <60 mg / dL or the presence of germs on positive examination and culture require drainage. Delays in drainage may increase morbidity and mortality rates. Management of empyema depending on the stage, antibiotics or thoracocentesis, thoracostomy, thoracostomy with fibrinolytic therapy, thoracoscopy, dekortication and open thoracotomy.

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respirasi@journal.unair.ac.id

Editorial Address
Jl. Mayjen Prof. Dr. Moestopo 6-8 Surabaya 60286 Indonesia

Location
Kota surabaya,

Jawa timur

INDONESIA

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Home Page

OAI Link

Editorial Team

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Reviewer

Google Scholar

Contact Name -

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Phone -

Journal Mail Official respirasi@journal.unair.ac.id

Editorial Address Jl. Mayjen Prof. Dr. Moestopo 6-8 Surabaya 60286 Indonesia

Location Kota surabaya, Jawa timur INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
respirasi@journal.unair.ac.id

Editorial Address
Jl. Mayjen Prof. Dr. Moestopo 6-8 Surabaya 60286 Indonesia

Location
Kota surabaya,

Jawa timur

INDONESIA