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All Journal Jurnal Respirasi (JR) JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Abimanyu: Journal of Community Engagement Jurnal Pengabdian Masyarakat Bhinneka Jurnal Pengabdian Masyarakat Bangsa
Herley Windo Setiawan
Department Of Pulmonology And Respiratory Medicine, Faculty Of Medicine, Universitas Airlangga, Surabaya, Indonesia.
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Appendicular Tuberculosis as Manifestation of Gastrointestinal Tuberculosis: A Case Report Yuliza Yuliza; Alfian Nur Rosyid; Wiwin Is Effendi; Prastuti Asta Wulaningrum; Herley Windo Setiawan
Jurnal Respirasi Vol. 7 No. 3 (2021): September 2021
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (344.745 KB) | DOI: 10.20473/jr.v7-I.3.2021.122-126

Abstract

Introduction: Gastrointestinal tuberculosis (GI TB) is quite rare with 3% incidence of all extrapulmonary involvement. Appendicular TB may occur in 0.1 - 3% of cases. Diagnosis is often difficult because the patient usually complains about chronic abdominal pain and fever. A definite diagnosis is based on histopathological examination of resected specimens from the appendectomy procedure.Case: We present a 37-year-old male patient admitted to the hospital with chronic abdominal pain, fever, nausea, and loss of body weight. The patient never had a persistent cough, hemoptysis, or night sweating. Physical examination showed pain and muscular rigidity in the right iliac area during palpation with Blumberg's sign and Rovsing's sign positive. Abdomen ultrasound imaging showed an appendicular abscess. The patient underwent appendectomy afterwards with histopathology result showing TB. The patient was treated with first category anti-tuberculosis drugs (ATD).Discussion: Diagnosis of appendicular TB is difficult due to unspecific clinical presentations. Appendicular TB patients often complain of signs and symptoms which are similar to acute appendicitis. These conditions can delay ATD treatment because the definitive diagnosis could be made after histopathological examination.Summary: Appendicular TB is a rare case of extrapulmonary TB. It can present as acute appendicitis. The definitive diagnosis is based on the histopathological examination. It is recommended to check the appendicectomy specimens histopathologically to exclude TB or other diseases. 
Pemphigus Paraneoplastik pada Timoma : [Pemphigus Paraneoplastic in Thymoma: A Rare Case] Herley Windo Setiawan; Daniel Maranatha
Jurnal Respirasi Vol. 4 No. 1 (2018): Januari 2018
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (645.973 KB) | DOI: 10.20473/jr.v4-I.1.2018.5-11

Abstract

Thymomas are mediastinal primary tumour of the mediastinum and associated with a variety of autoimmune disorders often linked to T-cell mediated autoimmunity. Paraneoplastic pemphigus (PNP) is an immunologically mediated skin disease characterized by epidermal blisters that may occur in association with thymic or non thymic neoplasms. Case: 21 years old man came to the hospital with vesicles and ulcer in oral cavity and extended to whole body since 3 weeks before. Patient was diagnosed with Pemphigus vulgaris and thymomas since 2 years. Patient was hospitalized for 3 times with same cases. Patient underwent chemotherapy Carboplatin-Etoposide 6 series and Radiotherapy 25 series and no response had been documented. Patient was suggested to undergo a resection of thymoma to prevent the exacerbation of pemphigus but he refused. The medication given was only aimed for reducing the exacerbation of Pemphigus. Discussion: PNP is characterized by the production of autoantibodies against various target antigens, mainly plakin family proteins and desmogleins. PNP results from an antitumor immune response cross-reacting with the normal epithelial proteins and thereby inducing autoimmunity by molecular mimicry. PNP sera bind to homologous region within carboxyterminus of members of the plakin gene family. There are also involvement of dysregulation of T-cell development. Conclusion: Pemphigus is rarely associated with Thymomas, but the fact there is an association between Thymomas and pemphigus. According to this fact, every patients with pemphigus should be suspected with malignancies especially thymomas until it was ruled out.
Upaya Peningkatan Kapasitas Mahasiswa Keperawatan dalam Menghadapi Pandemi COVID-19 Ika Nur Pratiwi; Herley Windo Setiawan; Lailatun Nimah; Rista Fauzinigtyas; Zulfayandi Pawanis
Abimanyu : Jornal of Community Engagement Vol 1 No 3 (2020): Special Issue Covid-19
Publisher : Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (398.902 KB) | DOI: 10.26740/abi.v1i3.11351

Abstract

The Covid-19 pandemic made health workers at the forefront must provide direct treatment to patients and take efforts to prevent the spread of the disease. The impact of the pandemic in the education is made all higher education institutions in all zones to provide online learning. Developing online learning for nursing students needs strategies because the competencies had achieved involve cognitive, affective and psychomotor domains. The purpose of community service (PKM) is to provide education about Covid-19 as an effort to increase the capacity of nursing students in the face of the COVID-19 pandemic. The PKM method uses the Community Based Research (CBR) approach through education about the latest management of Covid-19, nursing care for Covid-19 patients and alertness based on transmission of COVID-19 (Transmition based Precaution). The final evaluation of the PKM program by comparing the pre-test and post-test scores on knowledge. PKM results, there were 178 participants with an average age of 22 years and the majority of them were women (104 participants). The measurement results for the level of knowledge p = 0.000 (p <0.05) so that there is a significant difference in the level of knowledge between before and after being given education. Community service activities include increasing knowledge and understanding of nursing students in dealing with Covid-19 in a clinical setting. So, after students graduate and then work, they can quickly adapt to the work environment in breaking the chain of health problems that occur.
Arterial Blood Gas Parameters to Evaluate Oxygenation and Acid-Base Disorders in Corticosteroid-Receiving Severe and Critical COVID-19 Patients Temenggung, Bintang; Setiawan, Herley Windo; Rochmanti, Maftuchah; Rosyid, Alfian Nur
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 15 No. 2 (2024): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V15I22024.64-69

Abstract

Highlights: Both severe and critical COVID-19 patients primarily presented with hypoxemia. Severe and critical COVID-19 patients differed through their tendencies towards respiratory alkalosis/metabolic acidosis and respiratory acidosis, respectively.   Abstract Introduction: Increased inflammation and immune dysregulation in severe and critical COVID-19 trigger oxygen and acid-base disorders, possibly mitigated by corticosteroids. Variations in arterial blood gas (ABG) parameters and the influence of corticosteroid administration have become a concern for clinicians. This study aimed to uncover significant differences in temporal arterial blood gas parameters between severe and critical COVID-19 cases undergoing corticosteroid treatment. Methods: This case-control study, which adhered to the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines, analyzed severe (n=27) and critical (n=41) COVID-19 patients treated in the high care unit (HCU) and the intensive care unit (ICU) of Universitas Airlangga Hospital, Surabaya, from May to July 2021. Arterial blood gas results were categorized into three evaluations (E1-E3) based on collection days. The International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) for Macintosh version 27.0 was used for statistical analysis, with a p<0.05 considered statistically significant. Results: Hypoxemia through PaO2 and P/F ratios was prominent in both groups throughout E1-E3, with differences only in E1 P/F ratios (p=0.003). While SaO2 stayed normal in severe cases, critical cases were low, with differences in E1 (p=0.012) and E3 (p=0.004). Severe cases maintained normal pH, while critical cases tended towards acidemia, notably differing in E1-E3. Both groups had low HCO3 levels, differing only in E2 (p<0.001). Severe and critical groups exhibited low and high PaCO2 trends, respectively, with distinctions in E2 (p<0.001) and E3 (p=0.003). Conclusion: Hypoxemia was prevalent in both groups. Compensated respiratory alkalosis or metabolic acidosis was common in the severe group, while the critical presented with respiratory acidosis.
Hubungan Perilaku Merokok Terhadap Kualitas Hidup Pasien Penyakit Paru Obstruktif Kronis (PPOK) Fazmi, Tatu Indira Khairunnisa; Artanti, Kurnia Dwi; Setiawan, Herley Windo
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Vol.9 No.1 Mei 2023
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v9i1.11036

Abstract

COPD mengacu pada serangkaian gangguan di mana aliran udara terbatas karena kelainan saluran napas atau alveolar dan di mana gejala pernapasan bertahan dari waktu ke waktu. Penyakit ini hasil dari kontak yang terlalu lama dengan zat beracun. Ketika peradangan terus-menerus hadir, saluran udara menyempit, mengurangi recoil paru. Berkurangnya partisipasi dalam aktivitas sehari-hari dikaitkan dengan kualitas hidup yang lebih rendah bagi penderita COPD, dan kondisi yang disebutkan di atas dapat berkontribusi pada hal ini. Para peneliti di Rumah Sakit Universitas Airlangga ingin mengetahui seberapa besar dampak merokok terhadap kualitas hidup pasien PPOK. Penelitian ini menggunakan pendekatan penelitian analitik observasional cross-sectional. Pengambilan sampel berturut-turut digunakan untuk memilih 90 peserta yang memenuhi kriteria inklusi dan eksklusi penelitian. Data sekunder dikumpulkan dari rekam medis, sedangkan data primer dikumpulkan melalui kuesioner yang diberikan kepada pasien di Klinik Paru RSUA. Dalam penelitian ini, kebiasaan merokok partisipan dijadikan sebagai variabel bebas. Sementara kualitas hidup menjadi fokus penelitian ini yang merupakan variabel dependen. Uji chi-square dilakukan pada data. Di Rumah Sakit Universitas Airlangga, pasien dengan penyakit paru obstruktif kronik memiliki kualitas hidup yang lebih buruk secara signifikan jika mereka merokok (p=0,023). Oleh karena itu, kecenderungan seseorang untuk merokok berpotensi berdampak negatif pada kualitas hidup mereka jika mereka menderita PPOK. Oleh karena itu diperlukan peningkatan pengetahuan kepada pasien PPOK terkait dengan akibat perilaku merokok kepada kualitas hidup.
Peningkatan Daya Tahan Tubuh Warga yang Berisiko Tertular Tuberkulosis Melalui Peningkatan Pengetahuan Pemanfaatan Tanaman Kelor-Pegagan di Desa Beru, NTT Mustika, Arifa; Khaerunnisa, Siti; Fatimah, Nurmawati; Setiawan, Herley Windo; Amustikarani, Dewa Ayu Praba; Stefanus, Lusiana
Jurnal Pengabdian Masyarakat Bhinneka Vol. 4 No. 2 (2025): Bulan November
Publisher : Bhinneka Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58266/jpmb.v4i2.695

Abstract

Latar Belakang. Desa Beru terletak di Alok Timur, Sikka, Nusa Tenggara Timur, Indonesia., yang memiliki tersangka jumlah penderita diatas 400 orang, jumlah ini menduduki tempat pertama diantara desa lain di kecamatan tersebut. Data ini menunjukkan bahwa perlu dilakukan identifikasi permasalahan untuk mempercepat penurunan angka penderita tuberculosis. Permasalahan terkait tingginya isidensi dan prevalensi tuberkuosis di Desa Beru, Kecamata Sikka Alok timur, yang dapat diidentifikasi adalah tingginya angka penularan TB yang disebabakan oleh kurangnya sosialisasi dan edukasi tentang pengetahuan masyarakat tentang cara penularan TB dan pemahaman tentang daya tahan tubuh serta pemanfaatan bahan lokal untuk meningkatkan daya tahan Tujuan Kegiatan pengabdian kepada masyarakat adalah untuk meningkatkan daya tahan tubuh penderita tuberkulosis (TBC) serta warga yang berisiko tertular melalui peningkatan pengetahuan dan pemanfaatan tanaman herbal lokal, yaitu Kelor (Moringa oleifera) dan Pegagan (Centella asiatica). Program dilaksanakan di Desa Beru, Kabupaten Sikka, Nusa Tenggara Timur, melalui pendekatan edukatif-partisipatif yang melibatkan penyuluhan kesehatan, demonstrasi pembuatan olahan herbal, serta distribusi produk fungsional berbasis tanaman lokal. Hasil kegiatan menunjukkan peningkatan signifikan pada tingkat pengetahuan peserta mengenai TBC dan manfaat tanaman herbal sebesar 22%, serta peningkatan ketrampilan pembuatan teh kelor dan pegagan. Kegiatan ini mendukung pencapaian Tujuan Pembangunan Berkelanjutan (SDGs) terutama pada poin 3,2,1, dan 17melalui pemanfaatan sumber daya hayati lokal untuk kesehatan masyarakat. Kesimpulan adalah peningkatan pemahaman tentang Penggunaaan tanaman kelor dan pegagan terhadap peningkatan daya tahan tubuh sebesar 22% pada kader kesehatan Desa Beru, Maumere, NTT. Kader kesehatan Desa Beru, Maumere, NTT memperoleh pengetahuan dan ketrampilan tentang pembuatan teh kelor dan pegagan.
Upaya Peningkatan Kualitas Hidup Pasien TB Melalui Penyuluhan Dagusibu Obat Pada Masyarakat di Desa Lepolima Provinsi Nusa Tenggara Timur Fatimah, Nurmawati; Setiawan, Herley Windo; Mustika, Arifa; Khaerunnisa, Siti; Kurniawan, Mohammad Akbar
Jurnal Pengabdian Masyarakat Bangsa Vol. 3 No. 10 (2025): Desember
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v3i10.3505

Abstract

Tuberkulosis (TB) merupakan masalah serius di Nusa Tenggara Timur (NTT). Data penelitian menunjukkan bahwa NTT merupakan provinsi dengan target deteksi kasus yang belum terpenuhi. Pemerintah Indonesia berkomitmen untuk menurunkan insiden TB melalui berbagai upaya, termasuk Rencana Pembangunan Jangka Menengah Nasional (RPJMN) 2020-2024 dan Strategi Eliminasi TB Nasional. Pengendalian TB di NTT menghadapi tantangan yang kompleks, seperti terbatasnya akses terhadap layanan kesehatan, kurangnya kesadaran masyarakat tentang pengobatan penyakit ini, dan terbatasnya sumber daya manusia di sektor kesehatan. Oleh karena itu, diperlukan upaya yang lebih efektif untuk meningkatkan deteksi kasus TB, pengobatan rasional yang menjangkau semua tingkat, serta penguatan skrining dan investigasi kontak. Solusi yang ditawarkan dalam kegiatan pengabdian masyarakat meliputi kegiatan pencegahan melalui penyuluhan kesehatan dengan memberikan penyuluhan tentang cara mencegah penyakit menular dan edukasi tentang DAGUSIBU (Dapatkan, Gunakan, Simpan, dan Buang). Tahap awal kegiatan ini adalah mengukur tingkat pemahaman tenaga kesehatan atau kader kesehatan mengenai definisi tuberkulosis, kemungkinan tindakan pencegahan, pengobatan, dan gaya hidup pasien. Setelah pre-test, akan dilakukan kuliah edukasi mengenai topik-topik tersebut. Peningkatan pemahaman relawan kesehatan dapat diukur setelah kegiatan menggunakan post test. Terdapat peningkatan rata-rata skor pre test dan post testl, dengan skor pre test rata-rata 56,8 dan skor post test rata-rata 77,3. Target luaran yang diharapkan dari kegiatan ini adalah meningkatnya pemahaman relawan kesehatan tentang Program DAGUSIBU dan upaya yang dapat dilakukan untuk mencegah peningkatan jumlah penderita TB di Desa Lepolima.Mumere, Nusa Tenggara Timur
Co-Authors Amustikarani, Dewa Ayu Praba Arifa Mustika Effendi, Wiwin Is Fatimah, Nurmawati Fazmi, Tatu Indira Khairunnisa Ika Nur Pratiwi Khaerunnisa, Siti Kurnia Dwi Artanti Kurniawan, Mohammad Akbar Maftuchah Maftuchah Maranatha, Daniel Nimah, Lailatun Pawanis, Zulfayandi Prastuti Asta Wulaningrum Rista Fauzinigtyas Rosyid, Alfian Nur Stefanus, Lusiana Temenggung, Bintang Yuliza Yuliza