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Cendekia Journal of Pharmacy
Published by Institut Teknologi Kesehatan Cendekia Utama Kudus
ISSN : 25992163     EISSN : 25992155     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Cendekia Journal of Pharmacy published by the Program Studi Farmasi STIKES Cendekia Utama Kudus with registered number ISSN 2599-2163 (Print) and for ISSN (Online) is 2599-2155. This journal is published twice a year, in November and May.
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Articles 12 Documents
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Search results for , issue "Vol 8, No 3 (2024): Cendekia Journal of Pharmacy" : 12 Documents clear
FORMULASI SEDIAAN PATCH TRANSDERMAL EKSTRAK DAUN BELIMBING WULUH (Averrhoa bilimbi L.) DAN UJI AKTIVITAS ANTIPIRETIK Andriani, Disa; Ovikariani, Ovikariani; Kusuma, Eka Wisnu
Cendekia Journal of Pharmacy Vol 8, No 3 (2024): Cendekia Journal of Pharmacy
Publisher : Institut Teknologi Kesehatan Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/cjp.v8i3.318

Abstract

Daun Belimbing wuluh mempunyai aktivitas antipiretik karena mengandung flavonoid, terpenoid, steroid. Pemilihan sediaan patch pada penelitian kali ini karena sediaan patch dapat mengontrol penghantaran obat, menghindari first pass metabolisme dan mencegah iritasi pada saluran pencernaan. Penelitian ini bertujuan untuk melihat aktivitas antipiretik daun belimbing wuluh dalam sediaan patch trandermal  yang dibuat dalam 2 konsentrasi yaitu 0,5% dan 1%. Ekstraksi daun belimbing wuluh menggunakan metode maserasi dengan pelarut etanol 96% dan dibuat 2 formula sediaan patch transdermal. Uji sifat fisik yang dilakukan meliputi uji organoleptis, uji keseragaman bobot, uji pH, uji ketebalan, uji daya tahan lipatan dan uji daya serap kelembapan. Uji aktivitas antipiretik dilakukan dengan hewan uji mencit yang diinduksi dengan ragi brewer. Data yang diperoleh diolah dengan statistik Analysis of Variance. Hasil Uji menunjukkan Patch Transdermal ekstrak daun belimbing wuluh memenuhi kontrol kualitasnya. Hasil uji antipiretik Patch transdermal ekstrak etanol daun belimbing wuluh pada formula 1 dengan konsentrasi ekstrak 0,5% dan formula 2 dengan konsentrasi ekstrak 1% memiliki efek antipiretik yang hampir sama, tetapi pada formula 2 memberikan efek daya antipiretik yang lebih tinggi dibanding dengan formula 1.
HUBUNGAN ANTARA PARITAS, USIA KEHAMILAN, DAN KADAR HEMOGLOBIN DENGAN BERAT BADAN LAHIR DI KLINIK BERSALIN KABUPATEN KUDUS Saputro, Arief Adi; Rahmawaty, Annis
Cendekia Journal of Pharmacy Vol 8, No 3 (2024): Cendekia Journal of Pharmacy
Publisher : Institut Teknologi Kesehatan Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/cjp.v8i3.312

Abstract

Background: Birth weight is an indicator of newborn health, where a baby is born healthy and full term. In general, they have a birth weight of around 3000 grams. In general, normal birth weight for a baby is between 3000 grams and 4000 grams, and if it is below or less than 2500 grams it is said to be low birth weight.Objective: To determine the relationship between parity, gestational age, and hemoglobin levels with birth weight at the Kudus Regency Maternity Clinic.Method: This research is analytical observational with a cross sectional approach using total sampling techniques.Results: There is a relationship between parity and birth weight as proven using the Spearman Rank test with a p value of 0.034 (p0.05). There is a relationship between gestational age and birth weight as proven using the Spearman Rank test with a p value of 0.000 (p0.05). There is a relationship between hemoglobin levels and birth weight as proven using the Spearman Rank test with a p value of 0.000 (p0.05)Conclusion: There is a relationship between parity, gestational age, and hemoglobin levels with birth weight.

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