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INDONESIA
Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Published by Perhimpunan Dokter Spesialis Patologi Klinik Indonesia
ISSN : 08544263     EISSN : 24774685     DOI : https://dx.doi.org/10.24293
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience
Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) is a journal published by “Association of Clinical Pathologist” professional association. This journal displays articles in the Clinical Pathology and Medical Laboratory scope. Clinical Pathology has a couple of subdivisions, namely: Clinical Chemistry, Hematology, Immunology and Serology, Microbiology and Infectious Disease, Hepatology, Cardiovascular, Endocrinology, Blood Transfusion, Nephrology, and Molecular Biology. Scientific articles of these topics, mainly emphasize on the laboratory examinations, pathophysiology, and pathogenesis in a disease.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 8 Documents
 1 
Search results for , issue "Vol 15, No 1 (2008)" : 8 Documents clear
KEGUNAAN SISTEM PENGOTOMATAN (OTOMASI) LABORATORIUM/ LAS (LABORATORY AUTOMATION SYSTEMS) Prihatini .
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 15, No 1 (2008)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v15i1.952

Abstract

In most laboratory LAS (Laboratory Automation System) system recently have been used. though, not all of them used theautomation system and LIS.the LAS is used for the diagnosis of diseases, because it can decrease the error factors as weel as thelaboratoric examination. Regarding to decreasing problems, the expenses of patients who staying in the hospitals could be reduced aswell as their time to stay. the purpose of this article is to know comprehensively LAS and its services in the future in the hospitals' clinicallaboratory. Because before LAS was used the diagnosis time of diseases take a long time as compared to LAS.
ANEMIA DAN DEFISIENSI BESI PADA SISWA SLTP NEGERI I CURUG, TANGERANG Fify Henrika; T. Silangit; Riadi Wirawan
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 15, No 1 (2008)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v15i1.943

Abstract

A research was conducted to 69 female students from a junior high school (SLtP) Negeri I Curug, tangerang aged 12–14 yearsto obtain percentages of anemia and iron deficiency in female adolescents. Anemia was found on 10.2% of the students, with 4.3%of normocytic normochromic anemia and 5.8% of microcytic hypochromic anemia. Microcytic hypochromic erythrocytes was foundon 21.7% of the subjects which consist of 2.9% iron deficiency anemia, 1.4% phase 2 iron deficiency (latent) with possibility ofhemoglobinopathy, and 2.9% phase 1 iron deficiency (pre-latent) with possibility of hemoglobinopathy. Anemia without iron deficiencywith possibility of chronic diseases and/or hemoglobinopathy was 2.9%, and without anemia nor iron deficiency but with possibility ofhemoglobinopathy was 11.6%. Iron deficiency was found among 26.1% of subjects which consist of 11.6% pre-latent iron deficiency,8.7% latent iron deficiency, and 5.8% iron deficiency anemia with 2.9% and 2.9% were normocytic normochromic anemia andmicrocytic hypochromic anemia, respectively.
MASALAH KETAHANAN (RESISTENSI) VANCOMYCIN TERHADAP ENTEROCOCCI urhayana Sennang AN
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 15, No 1 (2008)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v15i1.957

Abstract

Enterococcus adalah bakteri komensal dalam usus (colon) manusia dan binatang, dapat menyebabkan infeksi saluran kemih,endokarditis dan infeksi intra abdominal. Vancomycin-resistant enterococci (VRE) merupakan masalah kesehatan utama di berbagainegara. VRE yang merupakan cadangan (reservoir) glycopeptide resistance dianggap dapat menjangkit ke manusia melalui persentuhan(kontak) dengan binatang atau memakan (konsumsi) daging. Walaupun E. faecalis lebih sering terjadi infeksi di manusia, tetapivancomycin resistance lebih sering ditemui di isolat E. faecium. VRE merupakan patogen pada populasi imunokompromis terutamapenderita yang mendapatkan berbagai antibiotik dan menjalani rawat inap yang lama. terdapat enam tipe glycopeptide resistanceyang dilaporkan mengenai enterococcus yaitu VanA, VanB, VanC, VanD, VanE dan Vang. VRE merupakan salah satu penyebab infeksinosokomial dan kerentanannya (kemampuan resistensinya) dapat berpindah antar organisme atau spesies lainnya. Untuk itu kebijakanpengendalian infeksi (infection control) dan panduan pemberian antibiotik sangat penting diterapkan untuk mengendalikan penyebaranVRE dan organism yang rentan (resisten) terhadap berbagai obat.
GAMBARAN FUNGSI HATI DAN GINJAL PADA PENDERITA MALARIA Darmawaty .; Fitriani M; Ruland DN Pakasi; Hardjoeno .
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 15, No 1 (2008)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v15i1.950

Abstract

the prevalence of malaria disease is still high in Indonesia. It requires to be diagnosed and handled quickly to decrease themorbidity and the mortality. the purpose of this study was to evaluate the results liver and kidney function tests of malaria patients forcomplications and to know the etiology. A cross sectional method was used for this study by using medical record of malaria patientsthat at Wahidin Sudirohusodo hospital in Makassar during January to December 2006. Malaria was diagnosed based on pheripheralblood while the examination of Sgot, SgPt (DgKC method), ureum (Barthelots method) and creatinine (Jaffe's method) were doneby chemistry autoanalizer. the increasing concentration of Sgot was found on 14 patients (42.4%) which was consisted of high at 12patients, SgPt on 13 patients (39.4%), ureum on 2 patients (6.1%) and creatinine on 11 patients (33.3%). Plasmodium falciparum wasfound on 18 patients (54.5%) and Plasmodium vivax on 15 patients (45.5%). the Sgot, SgPt, ureum, and creatinine concentrationsmostly exist in normal range, this indicated that liver and kidney damage was still mild. the etiology of malaria disease was Plasmodiumfalciparum and Plasmodium vivax, it was found from examination of pheripheral blood. there was no significant different in this studyfor the increasing of Sgot, SgPt, ureum and creatinine concentrations based on plasmodium etiology.
DIAGNOSIS FILARIASIS BERDASAR HAPUSAN DARAH TEPI H. I. Malewa; Prihatini .
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 15, No 1 (2008)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v15i1.951

Abstract

Filariasis is a disease group affecting humans and animals caused by nematode parasites of the order Filariidae, commonly calledfilariae. Filarial parasites may be classified according to the habitat of the adult worms in the vertebral host. the lymphatic groupincludes Wucheria bancrofti, Brugia malayi and Brugia timori. the cutaneous group includes Loa-loa, onchocerca volvulus, andMansonella streptocerca. the body cavity group includes Mansonella perstans and Mansonella ozzardi. these parasites are transmittedto humans through the bite of an infected mosquito. Clinical findings vary from asymptomatic until severe, depending on geography,parasite species, immune response and intensity of the infection A 19-years-old Javanese woman, presented with oedema on right legs.She has been suffering from oedema on right leg since she was 7-years-old. Physical examination showed elephantiasis on the right leg.Early, the patient had swelling in right inguinal area spreading into her right leg. the oedema was persistent and become larger untilnow. there was no fever and pain. She had history living in South Borneo when she was 1 until 4 years old. She did not receive anymedication before. Laboratory examination showed no abnormality both of complete blood count and clinical chemistry. From thin bloodsmear examination many forms of microfilariae were found. the data showed manifestation of filariasis in the blood.
AKTIVITAS SGOT, SGPT DI PENDERITA LUKA BAKAR SEDANG DAN BERAT Sri Nurul Hidayah; Mutmainnah .; H. Ibrahim Abd. Samad
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 15, No 1 (2008)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v15i1.942

Abstract

Burn injury is a kind of trauma with the high mortality and morbidity rate that needs special treatment since the very first phaseup to the end. this study targeted medium to severe burns, limited to liver complications. the objective of this study is to calculate andobserve the difference Sgot, SgPt activities in medium and severe burns. the Methods of this study was Cross Sectional, we conductedon 42 subjects with medium to severe burns, Hospitalised during the period of June 2005 to May 2007 at DR.Wahidin Sudirohusodohospital of Makassar. the data were calculated and statistically analysed using the SPSS V.11.5. We obtained of 12 (28.6%) mediumburn injuries and 30 (71.4%) severe burn injuries. In medium burn subjects the got showed normal activities in 6 subjects (50%) andhigh activities in 6 subjects (50%), the gPt showed normal activities in 8 subjects (66,7%) and high activities in 4 subjects (33.3%).In severe burn subjects the got showed normal activities in 6 subjects (20%) and high activities in 24 subjects (80%), the gPt showednormal activities in 13 subjects (43.3%) and high activities in 17 subjects (56.7%). there was no significant difference in the increasingactivities of Sgot and SgPt in either medium or severe burns, where p > 0.05. Increased activities of SgPt and Sgot was higher insevere burns than in medium ones. It was also obtained that increasing Sgot activities was found more often than SgPt in patientswith either medium or severe burns.
PENGARUH PENGAWET BEKU (CRYOPRESERVATION) TERHADAP KADAR EPIDERMAL GROWTH FACTOR (EGF) PADA SELAPUT AMNION Ety Retno S; Gunawan Effendi; Gatut Suhendro; I. Handojo
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 15, No 1 (2008)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v15i1.953

Abstract

to measure the difference of EgF concentration in between fresh amniotic membranes and with cryopreservation in 16 amnioticmembranes. Each amniotic membrane was divided into two parts. the first part was extracted in fresh forms and the second partunderwent cryopreservation with glycerol 50% and was stored at –80° C during 1 month before extraction. Both parts of the membranewere extracted using ultrasonic disintegrator and concentration of EgF was measured from the obtained extract using ELISA method.the average concentration of EgF in the fresh amniotic membrane was 122.76 ± 11.59 pg/g while the average concentration of EgFin the amniotic membrane underwent cryopreservation was 99.34 ± 9.49 pg/g. Average degradation of EgF concentration due tocryopreservation is 18.49% ± 10.20%. EgF concentration in fresh amniotic membrane is significantly higher than the EgF concentrationin amniotic membrane underwent cryopreservation (p = 0.000). Degradation of EgF concentration due to cryopreservation at 95%fidence interval is 12.33% to 24.66%
DETEKSI MOLEKULER Mycobacterium tuberculosis DI DAHAK CARA POLYMERASE CHAIN REACTION P. B. Notopuro; J. Nugraha; H. Notopuro
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 15, No 1 (2008)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v15i1.944

Abstract

tuberculosis is a chronic infectious disease which is found in developing and developed country. It is one of community healthproblems which become priority in national and international health programs. Microbiologic examination is used to establish thediagnosis of tuberculosis beside clinical examination and radiologic examination. Conventional microscopic and culture examinationhave many limitation ie: such as for example low sensitivity, specificity and need a lot of time. New Molecular technique gives morevalue in sensitivity, specificity and the time for examination. the aim of this study was to know the diagnostic value of PolymeraseChain Reaction for detection of Mycobacterium tuberculosis in sputum. the sputum was collected from twenty eight patients suspectedtuberculosis based on the clinical and radiological examination. the study was performed from September 2006 until July 2007. Wedid the conventional culture technique as a diagnostic gold standard and molecular technique to detect the Mycobacterium tuberculosisin the sputum. For molecular technique, we used Polymerase Chain Reaction (PCR) with a set of IS6110 region primer which is specificfor the Mycobacterium tuberculosis Complex. the sensitivity of PCR with IS6110 region primer is 100% (very high), specificity is 82.4%(high), positive predictive value is 89.7% and negative predictive value is 100%. there was statistically no significant difference betweenthe result of PCR and conventional culture method. Based on the result, the Polymerase Chain Reaction examination with primer IS6110region primer can be used as the screening tool for tuberculosis infection, while the clinician waits for culture result.

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