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Published by Future Science
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Articles 1,542 Documents
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Molecular Aspects of Colorectal Cancer Prognosis in 10 years
Nusantara Science and Technology Proceedings 4th Riau Medical Scientific and Expo 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2806

Abstract

Colorectal cancer (CRC) ranks third in the world with an increasing mortality rate, prompting an analysis of various studies that have been conducted over the last 10 years. The inclusion criteria of the analyzed research articles were studies involving the molecular aspects of colorectal cancer associated with its prognosis in the last 10 years. The international literature search method was carried out through article data published in Embase, Scopus, and PubMed using keywords: colorectal cancer, molecular aspects, and prognosis. Through the 440 articles found during the first search out, after going through the final selection stage, 29 articles were determined that met the inclusion criteria. The research method that is widely used in the research analyzed is immunohistochemistry accompanied by PCR. Various molecular aspects have been found to play a role in determining carcinogenesis, response to therapy, and the prognosis of CRC. They generally examine aspects of genes and progress towards microRNA and some molecular aspects are still useful in determining the prognosis so they are still being worked on at this time but further research is needed to further complement the existing data about CRC.
Evaluation of The Nervous System Interactive Module Based on Acceptance and Increasing Knowledge Level
Nusantara Science and Technology Proceedings 4th Riau Medical Scientific and Expo 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2807

Abstract

The use of interactive nervous system modules is expected to be suitable to increase knowledge and facilitate independent learning. The interactive module used must be tested for usability. Usability and user experience are the main determinants of the quality of a product in the form of media or systems, as well as an indicator of success or failure. The purpose of this study was to evaluate the use of an interactive nervous system module that was developed based on user acceptance and increased usage knowledge. A pre-experimental one group pre–test–post–test design with a sequential explanatory mixed method was taken. The sample of this study was all participants taking the comprehensive stage in March 2022. The quantitative measurement used the System Usability Scale (SUS) and the User Experience Questionnaire (UEQ), while the knowledge measurement used two packages of pretest and posttest questions. Further, the Qualitative measurements were carried out by interviewing to find out the advantages and disadvantages of the interactive modules that have been developed as well. There is evidence that the module increases the participant's knowledge (p-value was 0.000 using paired sample t-test). The average results of the pre-test and post-test scores were 68.33 and 83.06 respectively. The results of the measurement of user acceptance using SUS obtained a value of 73.125 which indicates that the interactive nervous system module is "Acceptable" based on acceptability ranges, "good" based on the adjective rating, and grade C based on the Grade Scale. UEQ measurement results obtained Overall “Excellent”, Pragmatic Quality “Excellent”, Hedonic Quality“Excellent”. The participants of the Comprehensive Stage said that the interactive nervous system module had advantages in terms of the system, easy access, attractive appearance and easy to understand. The drawback is that the use on mobile devices is still less comfortable when compared to use on laptops and tablets. Our study concludes that the use of these interactive nervous system modules is well acceptable as it can facilitate students' independent learning and increase knowledge. Moreover, Interactive modules also have advantages in terms of systems, ease of access, attractiveness and clarity of material, however the improvement in appearance to keep comfortable when user use on mobile devices is still needed.
The Bacteria on Saliva of Diabetes Mellitus Patients in Arifin Achmad General Hospital, Riau Province
Nusantara Science and Technology Proceedings 4th Riau Medical Scientific and Expo 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2808

Abstract

Diabetes Mellitus (DM) is a chronic non-communicable disease often found in the community. Patients with long-standing diabetes and uncontrolled blood glucose cause high salivary glucose levels and decreased salivary flow. This can be a medium for the growth and development of bacteria that can cause discomfort and various infections in the oral cavity. This research to know the characteristics of DM patients and the description of bacteria in the saliva of DM patients. The study was conducted by consecutive sampling method on DM patients who signed the informed consent, saliva samples were taken at the Arifin Achmad General Hospital, and the Microbiology Laboratory Faculty of Medicine, Universitas Riau for in vitro culture and identification of bacteria. Data processing is done manually and reported in the form of a frequency distribution table, expressed in percentages. The characteristics of research subjects from 30 samples obtained 14 men (46.66%), 16 women (53.33%), aged 33-67 years, elementary education 3 people (10%), junior high school 0 people (0%), high school 14 people (46.66%), PT 13 people (43.33%). DM status was controlled in 24 people (80%), and in uncontrolled 6 people (20%). The types of bacteria identified were Streptococcus sp 7 samples (17.5%), Streptococcus alpha hemolytic 2 samples (5%), Negative Coagulase Staphylococcus (CNS) 15 samples (37.5%), Staphylococcus aureus 2 samples (5%), Klebsiella sp 14 samples (35%). The conclusion of the research subjects are 33-67 years old, and most are women, with high school education, and controlled DM status. The most bacteria were Coagulase Staphylococcus (CNS) and Klebsiella sp.
Detection of Opportunistic Intestinal Protozoans in The Feces of Orphanage Children in Pekanbaru
Nusantara Science and Technology Proceedings 4th Riau Medical Scientific and Expo 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2809

Abstract

Opportunistic intestinal protozoa are intestinal protozoa that can infect humans and cause clinical symptoms depending on the patient’s immune status. In immunocompromised patients, infection by opportunistic intestinal protozoa can cause symptoms of diarrhea; mild to severe diarrhea. In addition to immunocompromised patients, these opportunistic intestinal protozoa can also be found in children with poor personal hygiene and environmental sanitation. This research was a descriptive study that aims to determine the incidence of opportunistic intestinal protozoa infection in orphanage children in Pekanbaru, which was conducted from August until October 2022. The result of microscopic examination with acid-fast staining were 70 samples of children’s feces from 8 of the orphanage found 41,4% were positive for opportunistic intestinal protozoans; consisting of 11.4% Cryptosporidium sp. infection, Blastocystis hominis as much as 21.4%, Cyclospora sp as much as 1.4%. and mixed infections of Blastocystis hominis and Cryptosporidium sp. as much as 7.2%. The prevalence of opportunistic intestinal protozoa found in the feces of orphanage children in Pekanbaru is high, but to our knowledge, these intestinal protozoans will not cause definite symptoms as long as the individual’s immune status is good.
Pre-testing of Genetic Literacy Questionnaire Reveals Genetics Misconceptions Among Medical Students of Universitas Riau
Nusantara Science and Technology Proceedings 4th Riau Medical Scientific and Expo 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2810

Abstract

Rapid advancement in genetics and genomics translates to its increasing relevancy in many sectors, including healthcare. In order to fully utilized genetic and genomic technologies in medicine, physicians, starting from medical students, need to have a good understanding on the subject. This study aimed to conduct genetic literacy questionnaire pre-testing on medical students of Universitas Riau. The International Genetic Literacy and Attitudes Survey (iGLAS) questionnaire was translated into Indonesian language. The initial translation was discussed in an expert review for construct validity as well as a student’s cognitive interview to review the language. Finally, internal consistency was tested on 34 students. The translated questionnaire had good construct validity. Review and interview suggested some wording changes to increase language understandability. The respondents had relatively low genetic literacy with mean score of 50.44 ± 11.57. The students had good knowledge regarding DNA nucleotides (70.6% correct answers) and function of a gene (97.1% correct answers). However, students overestimated the number of genes in human DNA (17.6% correct answers). We also found misconceptions regarding the term “genome” as all genes composition instead of all DNA sequences (32.4% correct answers). While the students know there are 23 chromosomes in human (73.5% correct answers), they misunderstood that each gene had 23 copies instead of 2 (23.5% correct answers). Other misconceptions were about genetic similarity between different cell types of an individual (20.6% correct answers), between family member (38.2% correct answers), and between random people (only one answered correctly, 2.9%). This result could lay the basis for intervention to increase genetic literacy among medical students.
Correlation Between Body Mass Index and Biological Age in Young Adults
Nusantara Science and Technology Proceedings 4th Riau Medical Scientific and Expo 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2811

Abstract

Background: Biological age is influenced by several factors including nutritional status. Body mass index (BMI) is an anthropometric measurement that can be used to assess a person's nutritional status. Objective: The purpose of this study was to determine the correlation between MT and biological age. Methods: Cross-sectional study on students of the Faculty of Medicine and Faculty of Nursing, the University of Riau in March – October 2022, n= 90 people, with consecutive sampling. Results: BMI has a significant, positive, and very strong correlation with biological age (p < 0.001, r = 0.965). Conclusion: The higher the BMI, the older the biological age, so that by reducing BMI is expected to improve biological age.
Postoperative Urinary Tract Calculi Culture – Is it necessary in Negative Urine Culture Patients?
Nusantara Science and Technology Proceedings 4th Riau Medical Scientific and Expo 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2812

Abstract

Postoperative infection in urinary tract calculi (UTC) cases still become an issue. It is accounted for up to one-tenth of patients experiencing urinary tract infections. Standardized preoperative urine culture help identify bacteria and antibiotic needed for UTC patients. Nevertheless, postoperative infection occurs even though no bacteria were found in urine preoperatively. This descriptive study aims to identify bacteria in calculi. Calculi culture and antibiotic sensitivity tests were carried out in patients with negative urine cultures who underwent endourology procedures from February to June 2022. Thirty-five negative urine culture cases consisting of 23 (46%) males and 12 (24%) females were identified. Positive calculi culture was identified in 11 (31.4%) cases with a previously negative urine culture. Escherichia coli, and Klebsiella pneumoniae were two prominent bacteria found. Among those patients, 5 (45.5%) cases develop SIRS and required antibiotic changes. Our data suggested added benefit of calculi culture in patients with stone disease, especially one enduring endourology procedure. An extensive study with larger sample size is required to decide whether routine calculi culture examination is necessary.
Seroprevalence of Anti-SARS-CoV-2 Among Pregnant Women Prior to COVID-19 Vaccination in Pekanbaru, Riau
Nusantara Science and Technology Proceedings 4th Riau Medical Scientific and Expo 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2813

Abstract

Pregnant women have higher risks for severe COVID-19. Therefore, this group requires protection, including in the form of vaccination. Generally, pregnant women are not included in the vaccine’s clinical trials, therefore safety data of COVID-19 vaccines for pregnant women are limited. As part of the safety and immunogenicity study of CoronaVac vaccine among pregnant women, we tested anti-S titer prior to vaccination. We recruited 45 women participating in the COVID-19 vaccination program. Only 3 of them (6.7%) reported having previous COVID-19 history. However, when tested for anti-S antibodies, more than half of the participants (26 persons, 57.8%) were reactive. Only one out of three participants reported previous COVID-19 infection was reactive for anti-S antibodies. Meanwhile, 25 (59.5%) of those who reported no previous infection were reactive. We found no factors influenced seropositivity, including gravida, gestational age, and healthcare profession. This high seropositivity among unvaccinated pregnant women who reported no previous infection reflected potential underreporting and underdetection of COVID-19 in the population.
Evaluation Usage of Interactive Quiz Reproductive Systems Based on Usability in Prospective UKMPPD Students
Nusantara Science and Technology Proceedings 4th Riau Medical Scientific and Expo 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2814

Abstract

The use of information technology and interactive multimedia in education is very important. The example of interactive multimedia or e-learning is an interactive quiz. There is multimedia that is easy to use, but sometime it make users confused. High usability of interactive application materials is an important element in ensuring maximum educational impact. This study aims to evaluate the usability, acceptance of interactive quiz media. This research was conducted on 20 student respondents of prospective UKMPPD participants. Interactive quiz media tested using reproductive system materials. Evaluation of interactive quizzes through usability testing with system usability scale (SUS) and user experience questionnaire (UEQ). User acceptance based on SUS is 72 with an acceptability rate in the acceptable category, a grade scale in the "C" category, which is quite good and an adjective rating in the good category. There are three categories of user acceptance based on UEQ with excellent predicates, namely attractiveness, accuracy and stimulation. There are two categories with the predicate good, namely clarity and novelty and one category with the predicate above average, namely efficiency. Assessment based on quality gets results above average on pragmatic quality, excellent on hedonic quality and excellent on overall quality. The measurement of user acceptance with the SUS and UEQ questionnaires obtained “acceptable” in terms of acceptability ranges, C in terms of grades scale, “good” in terms of adjective rating, “excellent” in terms of hedonic quality and “above average” in terms of pragmatic quality.
The Relationship Between Knowledge and Practice Towards the Covid-19 Health Protocol of Students of SMPN 20 Dumai
Nusantara Science and Technology Proceedings 4th Riau Medical Scientific and Expo 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2815

Abstract

According to the Joint Decree (SKB) of 4 ministers, the application of health protocols is an effective way to prevent the transmission of COVID-19 in schools. Beginning in 2022, face-to-face learning in schools has begun, and for that students' understanding of health protocols during face-to-face learning and vaccination will determine how to prevent COVID-19 in the school environment. This study aims to describe the knowledge and practice of the COVID-19 health protocols and vaccination at SMPN 20 students. A cross-sectional design with a purposive sampling technique and obtained a sample of 124 students was conducted. The instrument in this study used a validated research questionnaire. The results of this study showed the knowledge and practice of students on COVID-19 health protocol, as many as 79.8% of participants have been fully vaccinated status, and the knowledge and practice of students on COVID-19 vaccination, there was a significant relationship with the r result of 0.02. further, though students knew the benefits and side effects of vaccination, but were unable to understand or explain it well. The conclusion is that almost all students have good knowledge and practice regarding health protocols and vaccination. Though there was no significant relationship between student's knowledge and practice of the COVID-19 health protocol, there is a significant association between vaccination practices.

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