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Contact Name
Ricko Dharmadi Utama
Contact Email
apinaga53@gmail.com
Phone
+628125173861
Journal Mail Official
thmreditor@gmail.com
Editorial Address
Jl. Kenari 1 RT.8 No.8g Bumi Lingkar Basirih, Banjarmasin, Kalimantan Selatan, Indonesia
Location
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INDONESIA
Tropical Health and Medical Research Journal
ISSN : -     EISSN : 2684740X     DOI : https://doi.org/10.35916/thmr.v1i1
Tropical Health and Medical Research is an open access, peer-reviewed journal that publishing only original research on all aspects of tropical medicine and global health especially health related to the Muslim community. Journal content including viral, bacterial and parasitic infectious diseases, Vectors, Noncommunicable diseases, Epidemiology and population health, Drug, vaccine and diagnostic tool development, Other health issues related to the Muslim community
Articles 94 Documents
Factors Associated with Stunting in Toddlers in Indonesia: Analysis of the 2024 Indonesian Nutrition Status Survey (SSGI) for Evidence-Based Nutrition Policy Leka Lutpiatina; Muhammad Rizal
Tropical Health and Medical Research Vol. 8 No. 2 (2026): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v8i2.155

Abstract

Stunting remains a major public health challenge in Indonesia and is associated with multiple biological, maternal, social, and environmental factors. This study aimed to identify factors associated with stunting among toddlers in Indonesia and characterize geographic variation in stunting prevalence across provinces using the 2024 Indonesian Nutrition Status Survey (SSGI). This cross-sectional observational study used data from 298,970 toddlers across 38 provinces and 510 districts/cities. Weighted multivariable logistic regression with province as a fixed effect was used to estimate adjusted odds ratios (AORs), complemented by Global Moran’s I, Local Indicators of Spatial Association (LISA), and quantile mapping to assess geographic distribution and spatial autocorrelation. The prevalence of stunting was 22.7%. Males (OR 1.11), children living in rural areas (OR 1.32), those aged 24–35 months (OR 1.29), those with low birth weight (OR 2.08), and those born prematurely (OR 1.34) had higher odds of stunting. Lower parental education, iron supplementation of <90 tablets, incomplete antenatal care, maternal anaemia, chronic energy deficiency, inadequate sanitation (OR 1.44), inadequate drinking water (OR 1.45), and high residential density (OR 1.38) were also significantly associated with stunting (p < 0.05). Significant differences in adjusted odds were observed across provinces (?² = 618.977; p < 0.001), with the highest AORs in Highlands Papua (5.82; 95% CI: 3.55–9.56) and East Nusa Tenggara (4.69; 95% CI: 3.70–5.95), compared with Bali as the reference province. Spatial analysis demonstrated significant positive spatial autocorrelation (Moran’s I = 0.3634; Z = 2.7271; p = 0.01), with high-prevalence clustering in the eastern region. Stunting was associated with multiple individual, household, and environmental factors and showed significant geographic clustering across Indonesian provinces. Evidence-based, geographically targeted strategies should prioritise interventions from pregnancy through the first two years of life, nutritional literacy, immunisation coverage, sanitation, drinking water, and healthy housing, particularly in high–high spatial clusters.
Evaluation of Cinnamomum verum Bark Essential Oil as a Natural Antifungal Agent Against Dermatophytes Leka Lutpiatina; Annisa Aulia Damayanti; Akhmad Rhafianor; Neni Oktiyani; Aima Insana
Tropical Health and Medical Research Vol. 8 No. 2 (2026): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v8i2.156

Abstract

Dermatophytosis is a superficial fungal infection that remains a public health problem, particularly in tropical regions, with Trichophyton rubrum and Trichophyton mentagrophytes as the primary causes. Increasing limitations in the use of synthetic antifungals have encouraged the development of natural products as alternative therapies, including Cinnamomum verum stem bark essential oil. This study aimed to analyse the antifungal activity of C. verum stem bark essential oil against T. rubrum and T. mentagrophytes using the disc diffusion method. The study used a true experimental design with a posttest-only control group design. The essential oil was obtained through steam-water distillation with a yield of 0.25% (v/w). Tests against T. rubrum used concentrations of 1%, 2%, 5%, and 10%, while tests against T. mentagrophytes used concentrations of 5%, 10%, 15%, and 20%. Ketoconazole 2% was used as a positive control and dimethyl sulfoxide as a negative control. The inhibition zone diameter was measured after incubation and analysed using One-Way ANOVA and Post Hoc tests. The results showed that the essential oil inhibited the growth of both fungal species at all concentrations tested. The inhibition zone diameter against T. rubrum increased from 21.7 mm to 54.1 mm, while against T. mentagrophytes it increased from 33.6 mm to 48.2 mm. Statistical analysis showed a significant difference between the concentrations of both species (p<0.001). It was concluded that C. verum bark essential oil exhibited in vitro antifungal activity against both T. rubrum and T. mentagrophytes, with the inhibitory activity generally increasing with increasing concentrations. These findings demonstrate the potential of C. verum essential oil as a candidate for a natural antifungal agent based on local resources. Therefore, further research on the characterisation of active compounds, determination of MIC/MFC values, development of topical formulations, and in vivo testing and clinical trials are needed to support its use in dermatophytosis therapy.
Comparative Antibacterial Activity of Citrus hystrix DC. Leaf Essential Oil Against ESBL Klebsiella pneumoniae and Multidrug-Resistant Serratia marcescens Leka Lutpiatina; Norsyifa Norsyifa; Mahira Ainiyah Putri; Ratih Dewi Dwiyanti; Aima Insana
Tropical Health and Medical Research Vol. 8 No. 2 (2026): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The increasing antimicrobial resistance has driven the development of natural antibacterial sources, one of which is essential oils. This study aimed to analyse the antibacterial activity of lime leaf essential oil (Citrus hystrix DC.) against Extended Spectrum ?-Lactamase (ESBL)-producing Klebsiella pneumoniae and multidrug-resistant Serratia marcescens. The study used a true experimental design with a posttest-only control group design. The essential oils were tested at concentrations of 50%, 60%, 70%, 80%, 90%, and 100% using the well diffusion method with four replications. Ciprofloxacin served as a positive control and dimethyl sulfoxide as a negative control. Data were analysed using the Shapiro–Wilk test, Levene's test, one-way ANOVA, or Welch ANOVA, followed by post hoc tests according to data characteristics at a significance level of p<0.05. The results showed that lime leaf essential oil had antibacterial activity against both bacteria at all concentrations tested. For Klebsiella pneumoniae ESBL, the inhibition zone diameter increased from 6.83 mm at 50% concentration to 9.30 mm at 90% concentration, then decreased to 8.08 mm at 100%. For multidrug-resistant Serratia marcescens, the inhibition zone diameter increased from 7.80 mm to 14.00 mm at 90% concentration, then decreased to 11.20 mm at 100%. Statistical analysis showed a significant difference between the concentrations for both bacteria (p<0.001). In general, Serratia marcescens showed higher sensitivity than Klebsiella pneumoniae ESBL. Although its inhibitory power was still lower than ciprofloxacin, lime leaf essential oil has the potential to be developed as a natural antibacterial source against resistant Gram-negative bacteria.
Antibacterial Activity of Limau Kuit (Citrus hystrix DC.) Leaf Essential Oil Against Methicillin-Resistant Staphylococcus aureus and Multidrug-Resistant Pseudomonas aeruginosa Leka Lutpiatina; Fitria Audrey Mau'izah; Wina Fitria; Ratih Dewi Dwiyanti; Aima Insana
Tropical Health and Medical Research Vol. 8 No. 2 (2026): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Antibiotic resistance in pathogenic bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA) and Multi-drug-resistant Pseudomonas aeruginosa (MDR P. aeruginosa), has encouraged the development of alternative antibacterial agents from natural sources. This study aimed to analyse the antibacterial Activity of Limau Kuit (Citrus hystrix DC.) leaf essential oil against MRSA and MDR P. aeruginosa. The study used a true experimental design with a posttest-only control group design. The essential oil was obtained through steam-water distillation of Limau Kuit leaves and then tested at concentrations of 50%, 60%, 70%, 80%, 90%, and 100% using the well diffusion method. Positive controls included ciprofloxacin and ceftazidime, while dimethyl sulfoxide served as the negative control. Each treatment was repeated four times. Data were analysed using Welch ANOVA and Games-Howell tests for MRSA and Kruskal-Wallis and Mann-Whitney tests for MDR P. aeruginosa. The essential oil yield was 0.60% (v/w). All concentrations showed antibacterial activity against both test bacteria. The largest inhibition zone diameter against MRSA was obtained at 90% (22.23 ± 1.75 mm), while against MDR P. aeruginosa at 80% (13.98 ± 1.48 mm). Statistical analysis showed a significant difference between concentrations in MRSA (p < 0.001) and MDR P. aeruginosa (p = 0.003). Antibacterial activity against MRSA is higher than against MDR P. aeruginosa, which is thought to be related to differences in cell wall structure and resistance mechanisms of the two bacteria. Lime leaf essential oil has potential as a natural antibacterial against antibiotic-resistant bacteria. However, further research is needed to determine active compound content, mechanism of action, and the minimum inhibitory concentration and minimum bactericidal concentration.

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