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Anti-Fungal Activity Test of Sengkuang (Dracontomelon dao) Leaf Ethanol Extract on The Growth of Candida albicans Aima Insana
Tropical Health and Medical Research Vol. 4 No. 1 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.63

Candida albicans is an important opportunistic fungal pathogen that is responsible for the majority of fungal infections in humans. In healthy individuals, Candida colonizes mainly on the mucosal surfaces of the oral cavity, digestive tract, skin and genitals. Dracontomelon dao or known as Sengkuang has been used as a traditional medicine for various diseases. Based on various studies, Dracontomelon dao extract is reported to exhibit antimicrobial properties. This study aimed to analyze the antifungal activity of the ethanol extract of sengkuang (Dracontomelon dao) leaves on the growth of Candida albicans. The study used 96% ethanol extract by macerating the simplicia leaves of Dracontomelon dao originating from South Kalimantan, Indonesia. The antifungal activity was tested by well diffusion method at various concentrations of the test extract (10%, 20%, 30%, 40% and 50%). The results showed that the average diameter of the inhibition zones at concentrations of 10%, 20%, 30%, 40% 50% were 19.2 mm, 21.8 mm, 23.2 mm, 24.8 mm, 27 mm, respectively. Based on the results of the study, it was found that the ethanolic extract of sengkuang (Dracontomelon dao) leaves had antifungal properties against the growth of Candida albicans with the most effective concentration at a concentration of 50% with an average zone diameter of 27 mm. The content of phytochemical compounds from sengkuang leaf extract (Dracontomelon dao) are flavonoids, alkaloids, saponins, tannins, and triterpenoids. This secondary metabolite is thought to be able to inhibit the growth of the fungus Candida albicans. The ethanol extract of sengkuang leaves (Dracontomelon dao) has been shown to have antifungal activity in vitro so that it has the potential to be developed as an antifungal agent and can be a new solution in handling cases of Candida albicans infection.

Pengaruh Lama Penyimpanan Jamu Beras Kencur terhadap Pertumbuhan Kapang Fransiskus Xaverius Agung Pinto Laksono; Ratih Dewi Dwiyanti; Rifqoh Rifqoh; Aima Insana
Jaringan Laboratorium Medis Vol 4, No 2 (2022): November 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v4i2.8571

During the Covid-19 pandemic, people began to maintain their health, by using herbal medicine as an alternative treatment. One type of herbal medicine used is jamu beras kencur because it has properties to increase stamina, increase appetite, and relieve aches and cough disorders. In the Regulation of the Minister of Health of the Republic of Indonesia No. 007 of 2012 carrying herbs such as jamu beras kencur does not require marketing authorization. The quality of the herbal medicine produced has not been confirmed as feasible from microbial contamination, especially in molds, the number of yeast molds in the jamu beras kencur must comply with BPOM standards Number 32 of 2019 namely AKK 103 colonies/mL. This study aimed to determine the effect of the storage time of jamu beras kencur on mold growth with storage treatments of 0 hours, 4 hours, 8 hours, 12 hours, and 24 hours at room temperature. This type of research is a Quasi Experiment with a research design of One Group Pretest-Postest Design. The results of this study showed that the average AKK value was 0 hours 0.2x100 colonies/mL, 4 hours 0.4x100 colonies/mL, 8 hours 0.4x100 colonies/mL. 12 hours 0.8x100 colonies/mL and 24 hours 2.2x100 colonies/mL. These results stated that the jamu beras kencur met the BPOM standard requirements Number 32 of 2019 which was AKK 103 Colonies/mL. The results of the Kruskal Wallis test obtained a sig value of 0.286, it was concluded that there was no effect of storage time for the jamu beras kencur on the growth of molds. The identification results on the jamu beras kencur obtained fungal species, namely Aspergillus flavus, Aspergillus niger, and Penicillium sp. Suggestions for further researchers can examine the effect of storage time on mold growth in other types of herbal medicine.

Perbandingan Nilai Laju Endap Darah Dengan Metode Automatik Dan Metode Westergren Pada Pasien Tuberkulosis Rima Putri Wulandari; Ahmad Muhlisin; Wahdah Norsiah; Ratih Dewi Dwiyanti; Aima Insana
Jurnal Karya Generasi Sehat Vol. 1 No. 1 (2023): Edisi Desember Tahun 2023
Publisher : Poltekkes Kemenkes Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jkgs.v1i1.81

Pada pasien tuberkulosis terjadi peningkatan LED yang disebabkan oleh inflamasi yang menyebabkan eritrosit rouleaux mengendap dengan cepat sehingga nilai LED tinggi.Ada beberapa metode manual yang digunakan dalam pemeriksaan LED, salah satu metode manual yang dianjurkan oleh International Committee for Standardisation in Hematology (ICSH) adalah metode Westergren. Seiring perkembangan yang ada metode otomatis menjadi pemeriksaan LED yang digunakan untuk menghindari atau mengurangi resiko paparan petugas laboratorium terhadap kontaminasi agen infeksi dengan prinsip kerja memakai infrared yang memungkinkan membantu kecepatan pengendapan sel darah dengan waktu pemeriksaan 2 kali lebih cepat. Penelitian ini bertujuan untuk mengetahui bagaimana perbandingan nilai laju endap darah dengan metode automatik dan metode westergren pada pasien tuberkulosis. Jenis penelitian ini adalah survey analitik dengan rancangan study komparatif. Populasi penelitian ini adalah seluruh penderita tuberkulosis di Wilayah Puskesmas Cempaka yang berjumlah 36 orang. Hasil pemeriksaan LED pada pasien tuberkulosis dengan metode automatik memiliki rata-rata 36.97 mm/jam, pada metode westergren memiliki rata-rata 38.53 mm/jam. Berdasarkan uji T Dependent menunjukkan bahwa nilai p value 0.003 yang artinya terdapat perbedaan yang bermakna antara nilai laju endap darah dengan metode automatik dan metode westergren pada pasien tuberkulosis.

Number of Breast Milk Bacteria in Women with Normal Labor and Caesarean Delivery During Room Temperature Storage Habibah, Siti Noor; Muhlisin, Ahmad; Lutpiatina, Leka; Insana, Aima
Tropical Health and Medical Research Vol. 6 No. 1 (2024): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v6i1.111

The presence of microbes in each breast milk sample can be different, one of which is influenced by the method of delivery. The research aimed to analyze the effect of storage time for breast milk from mothers giving birth normally and giving birth by Caesarean on the number of bacteria at room temperature. The independent variable in this study was the storage time for breast milk from mothers giving birth normally and giving birth by Caesarean for 0, 4, 8, and 12 hours at room temperature, while the dependent variable in this study was the number of bacteria in the breast milk. The research samples were breast milk from mothers who gave birth normally and Caesarean section which was treated with storage at room temperature for 0, 4, 8, and 12 hours. The results of the research were that the average number of bacteria in breast milk from mothers giving birth normally, stored at 0, 4, 6, 8, and 12 hours respectively, was 1.33 x 104 CFU/ml; 2.18 x 104 CFU/ml; 5.04 x 106 CFU/ml; 1.68 x 107 CFU/ml. The average number of bacteria in breast milk from mothers giving birth by Caesarean storage 0, 4, 6, 8, and 12 hours respectively 1.83 x 104 CFU/ml; 1.73 x 105 CFU/ml; 1.76 x 107 CFU/ml; 6.67 x 107 CFU/ml. There is a significant difference in the number of bacteria between breast milk from mothers who gave birth normally and breast milk from mothers who gave birth by Caesarean section. Storage time has a positive effect on the number of bacteria in breast milk from mothers giving birth normally and giving birth by Caesarean. It is recommended to store breast milk at room temperature for up to 4 hours for breast milk from women giving birth normally and for breast milk from mothers giving birth by Caesarean, storage for less than 4 hours by paying attention to the cleanliness of the breast milk storage area.

Differences in Thawing Methods in Broiler Chicken Meat on Total Plate Count (TPC) of Bacteria Putri, Noorlaily; Lutpiatina, Leka; Nurlailah, Nurlailah; Insana, Aima
Tropical Health and Medical Research Vol. 6 No. 2 (2024): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v6i2.120

Total Plate Count (TPC) determines the number of microorganisms, both bacteria and fungi. Thawing is a step in thawing food that was previously stored frozen. This study aims to analyze the differences in the Total Plate Count of bacteria with variations in thawing methods in broiler chicken meat. Thawing methods commonly used include thawing at room temperature, soaking in water, and leaving it in the refrigerator (chiller). The type of research is experimental design with a posttest-only control design. Repetition was carried out five times for each control group KN (negative control) and test groups R0 (fresh chicken), R1 (frozen chicken), R2 (chicken thawed at room temperature), R3 (chicken soaked in water) and R4 (chicken thawed in the chiller) then the number of bacteria that grew was calculated. The average number of R0 colony results ranged from 4.1 x 103 CFU/g, R1 8.6 x 102 CFU/g, R2 1.6 x 104 CFU/g, R3 8.9 x 103 CFU/g and R4 1.2 x 103 CFU/g. The Kruskall-Wallis test results showed an Asymp sig value of 0.000 (<0.05); it can be concluded that there are differences in TPC in broiler chicken meat with variations in thawing methods that are thawed at room temperature, soaked in water and thawing in the chiller. It is recommended to thaw frozen chicken meat using the method of leaving it in the refrigerator because it has the lowest number of germs and can inhibit the growth of germs.

Penyuluhan Kebersihan Diri Dan Pendampingan Pembiasaan Pola Hidup Bersih Sehat (Pbhs) Serta Penanggulangan Skabies Pada Santri Pondok Pesantren Darul Hijrah Putra Martapura Rifqoh, Rifqoh; Insana, Aima; Rizani, Khairir
JURNAL RAKAT SEHAT (JRS) : Pengabdian Kepada Masyarakat Vol 1 No 2 (2022)
Publisher : UPPM Poltekkes Kemenkes Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jrs.v1i2.31

Scabies is a skin disease caused by Sarcoptes scabiei mite. Scabies is transmitted through direct or indirect physical contact regardless of socioeconomic status, gender, or age, especially in Islamic boarding schools. The high prevalence of scabies is caused by less personal hygiene and environmental sanitation dan Clean Healthy Lifestyle (PHBS) behavior. This PKM aims to improve knowledge, personal hygiene, environmental sanitation, and PHBS behavior in preventing scabies in Darul Hijrah Putra Martapura (DHP) Islamic Boarding School students. The implementation method was counseling, questionnaires, observation, early detection of scabies, treatment, and assistance in habituating PHBS for 3weeks to 53students of DHP. The results of microscopic examination with adhesive tape method showed 9(16.98%) students were positive for scabies, 6(11.32%) of them had mild symptoms and 3(5.66%) students had severe symptoms. The treatment was carried out for the positive scabies students. The results of evaluation after this PKM are scabies students have recovered, there is an increase in knowledge to 100% good after counseling, PHBS habituation results in the booklet and 52(99%) students increase in PHBS behavior scores, personal hygiene increases to a good category 45(84.91%) students. And the category is not good, with only 8(15.06%) students and the sanitation of the dormitory environment is quite good, except for the occupancy density, that 36m2 rooms occupied by 16 students (standard 1 person/9m2). There is an improvement in facilities and infrastructure. It is recommended to partners continue PHBS habituation assistance and carry out early detection on prospective students before enter DHP boarding schools.

Perbandingan Nilai Laju Endap Darah Dengan Metode Automatik Dan Metode Westergren Pada Pasien Tuberkulosis Putri Wulandari, Rima; Muhlisin, Ahmad; Norsiah, Wahdah; Dewi Dwiyanti, Ratih; Insana, Aima
Jurnal Karya Generasi Sehat Vol. 1 No. 1 (2023): Edisi Desember 2023
Publisher : Poltekkes Kemenkes Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jkgs.v1i1.81

Pada pasien tuberkulosis terjadi peningkatan LED yang disebabkan oleh inflamasi yang menyebabkan eritrosit rouleaux mengendap dengan cepat sehingga nilai LED tinggi.Ada beberapa metode manual yang digunakan dalam pemeriksaan LED, salah satu metode manual yang dianjurkan oleh International Committee for Standardisation in Hematology (ICSH) adalah metode Westergren. Seiring perkembangan yang ada metode otomatis menjadi pemeriksaan LED yang digunakan untuk menghindari atau mengurangi resiko paparan petugas laboratorium terhadap kontaminasi agen infeksi dengan prinsip kerja memakai infrared yang memungkinkan membantu kecepatan pengendapan sel darah dengan waktu pemeriksaan 2 kali lebih cepat. Penelitian ini bertujuan untuk mengetahui bagaimana perbandingan nilai laju endap darah dengan metode automatik dan metode westergren pada pasien tuberkulosis. Jenis penelitian ini adalah survey analitik dengan rancangan study komparatif. Populasi penelitian ini adalah seluruh penderita tuberkulosis di Wilayah Puskesmas Cempaka yang berjumlah 36 orang. Hasil pemeriksaan LED pada pasien tuberkulosis dengan metode automatik memiliki rata-rata 36.97 mm/jam, pada metode westergren memiliki rata-rata 38.53 mm/jam. Berdasarkan uji T Dependent menunjukkan bahwa nilai p value 0.003 yang artinya terdapat perbedaan yang bermakna antara nilai laju endap darah dengan metode automatik dan metode westergren pada pasien tuberkulosis.

HUBUNGAN KADAR HEMOGLOBIN DENGAN INDEKS MASSA TUBUH PADA PASIEN JIWA DI RUMAH SAKIT JIWA SAMBANG LIHUM Rumiyati; Ahmad Muhlisin; Akhmad Muntaha; Aima Insana
Jurnal Karya Generasi Sehat Vol. 2 No. 1 (2024): Edisi Juni 2024
Publisher : Poltekkes Kemenkes Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jkgs.v2i1.119

Gangguan jiwa adalah sekelompok gejala yang ditandai dengan perubahan pikiran, perasaan, dan perilaku seseorang yang menimbulkan disfungsi dalam menjalankan aktivitas sehari-hari. Hemoglobin merupakan salah satu senyawa dalam sel darah merah yang berfungsi mengangkut zat oksigen ke dalam sel-sel tubuh. Kadar hemoglobin dalam darah merupakan indikator laboratorium yang digunakan untuk menetapkan prevalensi anemia. Penelitian ini bertujuan untuk mengetahui hubungan kadar Hemoglobin dengan Indeks Massa Tubuh pada pasien jiwa. Metode yang digunakan Cross Sectional dengan tehnik sampling Accidental. Penelitian dilaksanakan tanggal 08 sampai 31 Agustus 2023. Populasi penelitian adalah pasien jiwa yang di rawat di Rumah Sakit Jiwa Sambang Lihum. Responden sebanyak 30 orang dengan Teknik pengambilan Total Sampling. Hasil penelitian kadar Hemoglobin pada pasien jiwa didapat nilai dibawah normal 15 orang (50 %), nilai normal 13 orang (43,3%), nilai diatas normal sebanyak 2 orang (6,7 %). Hasil pengukuran Indeks Massa Tubuh didapat hasil kurus sebanyak 7 orang (23,3 %), Normal sebanyak 18 orang (60,0 %), gemuk sebanyak 5 orang (16,7 %). Hasil analisa uji statistik Pearson didapatkan nilai pearson correlation 0.396 korelasi itu menunjukkan korelasi rendah. Nilai p value 0.030 pada Sig.2 tailed disimpulkan ada hubungan antara kadar Hemoglobin dengan Indeks Massa Tubuh pada pasien jiwa. Penelitian ini dapat memberikan informasi tambahan bagi tenaga medis dalam mengelola pasien jiwa yang memiliki masalah Kesehatan terkait kadar Hemoglobin dan Indeks Massa Tubuh. Kata kunci : Hemoglobin, Indeks Massa Tubuh, Pasien Jiwa

PERBEDAAN KANDUNGAN FECAL COLIFORM TERHADAP KONDISI PASANG DAN SURUT PADA SUNGAI BARITO DI KECAMATAN MARABAHAN Nur Ain Mirandayanti; Rifqoh; Roebiakto, Erfan; Insana, Aima
Jurnal Karya Generasi Sehat Vol. 2 No. 1 (2024): Edisi Juni 2024
Publisher : Poltekkes Kemenkes Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jkgs.v2i1.123

Penelitian ini fokus pada analisis kandungan fecal coliform sebagai indikator pencemaran tinja di Sungai Barito, Kecamatan Marabahan. Berdasarkan Peraturan Menteri Lingkungan Hidup dan Kehutanan RI No. 27 Tahun 2021, pengukuran fecal coliform digunakan untuk menentukan Indeks Kualitas Air (IKA). Penelitian ini melibatkan 54 sampel air dari Sungai Barito, dengan 27 sampel pada kondisi pasang dan 27 sampel pada kondisi surut. Hasil penelitian menunjukkan bahwa kandungan fecal coliform pada kondisi surut lebih tinggi (3096,29 MPN/100ml) dibandingkan kondisi pasang (1597,78 MPN/100ml). Kedua nilai tersebut melebihi batas baku mutu air nasional (100 MPN/100 ml), menunjukkan ketidaklayakan Sungai Barito sebagai sumber air baku. Analisis statistik menggunakan uji Wilcoxon menunjukkan perbedaan yang signifikan (p = 0,000), menegaskan pengaruh kondisi pasang surut terhadap kandungan fecal coliform. Disarankan untuk penelitian selanjutnya melibatkan parameter IKA lainnya guna mendapatkan pemahaman yang lebih komprehensif terkait kualitas air Sungai Barito.

PENGARUH KOMBINASI EKSTRAK ETANOL JAHE MERAH (Zingiber officinale var Rubrum), DAUN KELOR (Moringa oleifera), DAN MENIRAN HIJAU (Phyllanthus niruri L.) SEBAGAI ANTIBAKTERI Escherichia coli Hafidh, Muhammad; Dwiyanti, Ratih Dewi; Insana, Aima; Muhlisin, Ahmad
Jurnal Karya Generasi Sehat Vol. 2 No. 2 (2024): Edisi Desember 2024
Publisher : Poltekkes Kemenkes Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jkgs.v2i2.154

Penyakit diare disebabkan oleh infeksi bakteri Escherichia coli. Infeksi ini dilakukan dengan pemberian obat tanaman herbal dari bahan alam yaitu jahe merah, daun kelor, dan meniran hijau yang berpotensi sebagai antibakteri sebagai alternatif pengobatan, dikarenakan pengobatan dengan bahan kimia atau antibiotik mengalami efek resisten. Penelitian ini bertujuan untuk mengetahui pengaruh kombinasi ekstrak etanol jahe merah, daun kelor, dan meniran hijau sebagai antibakteri Escherichia coli. Jenis penelitian ini adalah True Exsperiment dengan rancangan penelitian adalah Posttest Only With Control Group Design dengan 7 formulasi kombinasi ekstrak etanol jahe merah, daun kelor, dan meniran hijau dengan 4 kali pengulangan. Uji antibakteri dilakukan dengan metode dilusi cair yaitu menentukan Kemampuan Menghambat dan Kemampuan Membunuh serta dengan metode difusi Zona Hambat Sumuran. Hasil penelitian pada Kemampuan Menghambat diukur dengan absorbansi sebelum dan sesudah inkubasi dari selisih rerata didapatkan formulasi F5 (2:1:1) yaitu 0.717 memiliki nilai yang dengan penurunan terbanyak dari semua formulasi. Pada Kemampuan Membunuh didapatkan hasil rata-rata 0 koloni yaitu pada formulasi F2 (1:1:2), F4 (1:2:2), F5 (2:1:1), dan F7 (2:1:2). Pada zona hambat sumuran didapatkan hasil rata-rata diameter dengan daya hambatan kuat adalah F4 (1:2:2) sebanyak 13.2 mm yang tertinggi dari semua formulasi. Dilakukan uji statistic Wilcoxon dan Kruskal-Wallis. Disimpulkan bahwa kombinasi ekstrak etanol jahe merah, daun kelor, dan meniran hijau formulasi yang efektif sebagai antibakteri Escherichia coli adalah formulasi F4 (1:2:2). Saran bagi peneliti selanjutnya dapat menggunakan konsentrasi bertingkat pada formulasi tersebut dari kombinasi ekstrak etanol jahe merah, daun kelor, dan meniran hijau sebagai antibakteri Escherichia coli.

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