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"Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS"
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<![CDATA[Analysis of Contamination of Lead Metal (Pb) and Cadmium (Cd) in Whitening Serum Circulating in Online Stores with Atomic Absorption Spectrophotometry ]]>
<![CDATA[Iswandi Iswandi]]>
<![CDATA[ AFAMEDIS Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS ]]>
Publisher : <![CDATA[Akademi Farmasi Mitra Sehat Mandiri Sidoarjo ]]>
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<![CDATA[Abstract Various cosmetic preparations are developing in line with technological developments in online marketing today, one of which is serum whitening. Whitening serum is a series of facial skin care products that contain certain active ingredients used for the health of facial skin with the aim of whitening the face. Online sales of cosmetics have a bad impact, namely the spread of cosmetics that have not been registered with BPOM, so it is feared that contamination from contamination materials such as heavy metals lead (Pb) and cadmium (Cd). So there is a need for a qualitative and quantitative analysis with atomic absorption spectrophotometry and method verification. This study aims to identify the presence of lead (Pb) and cadmium (Cd) metal contamination in whitening serums so as to advise consumers about the dangers of using these metals for facial skin health. The results showed that the 5 samples analyzed all contained lead metal contamination (Pb) in the range of 0.0191-0.0406 mg / L and cadmium metal (Cd) in the range of 0.7732-0.9871 mg / L. Results still met the requirements in accordance with the BPOM contamination limit, namely no more than 20 mg / L and no more than 5 mg / L. Thus, all the serum whitening sample is still within the safe limit according to the contamination limit by BPOM.]]>
<![CDATA[Analisa Manajemen Resiko Laboratorium Farmasetika Untuk Persyaratan ISO 9001:2015 Menggunakan Metode 5 Why Analysis ]]>
<![CDATA[Deddy Rusdiana]]>
<![CDATA[ AFAMEDIS Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS ]]>
Publisher : <![CDATA[Akademi Farmasi Mitra Sehat Mandiri Sidoarjo ]]>
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<![CDATA[Profesionalisme Sumber Daya Manusia bidang Farmasi tidak lepas dari pendidikan tinggi pencetak tenaga farmasi. Institusi pendidikan di tutut untuk terus memiliki standar kualitas tertentu . Institusi Pendidikan sebagaimana halnya dengan organisasi lainnya pasti akan selalu berhadapan dengan resiko, baik itu resiko yang berasal dari dalam maupun dari luar instansi pendidikan . Tujuan dari artikel ini yaitu untuk memberikan pengetahuan dalam bentuk analisa resiko yang dapat digunakan dalam manajemen resiko mutu terhadap masalah yang terjadi di Institusi pendidikan bidang Farmasi untuk mempersiapkan sertifikasi ISO 9001:2015. Pada artikel ini metode yang digunakan yaitu menggunakan metode 5 Why Analysys untuk menyusun analisa resiko . Artikel ini disusun melalui metode pengamatan dan wawancara, sedangkan rekomendasi disusun setelah potensi resiko dianalisis dengan metode 5 Why Artikel ini menghasilkan dokumen inventarisasi resiko dalam bentuk analisa resiko yang dapat digunakan dalam manajemen resiko mutu terhadap masalah yang terjadi di Laboratorium Farmasetika Mitra Sehat Mandiri Sidoarjo untuk mempersiapkan ISO 9001:2015 menggunakan metode 5 Why terhadap sertifikasi potensi resiko prioritas yang memiliki kategori level tertinggi .]]>
<![CDATA[KAJIAN YURIDIS PERATURAN MENTERI KESEHATAN REPUBLIK INDONESIA NOMOR 35 TAHUN 2014 TENTANG STANDAR PELAYANAN KEFARMASIAN DI APOTEK ]]>
<![CDATA[Deddy Rusdiana]]>;
<![CDATA[andry Priyoheriyanto]]>
<![CDATA[ AFAMEDIS Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS ]]>
Publisher : <![CDATA[Akademi Farmasi Mitra Sehat Mandiri Sidoarjo ]]>
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<![CDATA[Regulation of the Minister of Health of the Republic of Indonesia Number 35 of 2014 concerning Pharmaceutical Service Standards in Pharmacies is a regulation that contains service standards that must be met by pharmacies in providing pharmaceutical services to the public. This regulation aims to improve the quality of pharmaceutical services in pharmacies and ensure that medicines sold and distributed to the public are safe, effective and useful. However, there are several problems related to the implementation of the Regulation of the Minister of Health of the Republic of Indonesia Number 35 of 2014 concerning Pharmaceutical Service Standards in Pharmacies. First, there are still many pharmacies that do not meet the pharmaceutical service standards stipulated in the regulation. Some pharmacies still sell drugs without a doctor's prescription, provide drugs that have expired, and do not provide sufficient information to patients regarding drug use. a juridical study is needed that aims to evaluate the implementation of the Regulation of the Minister of Health of the Republic of Indonesia Number 35 of 2014 concerning Pharmaceutical Service Standards in Pharmacies and find solutions to overcome problems related to its implementation. So that it still needs improvement and improvement in terms of understanding, resources, and supervision. The proposed solutions can be a first step in addressing these issues and ensuring more effective enforcement of regulations in the future.]]>
<![CDATA[AKTIVITAS ANTIOKSIDAN DAN SKRINNING FITOKIMIA EKSTRAK ETANOL DAUN SINTRONG (Crassocephalum crepidioides (Benth) S. Moore) ]]>
<![CDATA[indah trilestari]]>;
<![CDATA[Panji Ratih Suci]]>;
<![CDATA[Erna Fitriany]]>
<![CDATA[ AFAMEDIS Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS ]]>
Publisher : <![CDATA[Akademi Farmasi Mitra Sehat Mandiri Sidoarjo ]]>
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<![CDATA[Antioxidants is an important role in the body's defense against disease, because antioxidant compounds are able to prevent the bad influence caused by free radicals. Sintrong leaves (Crassocephalum crepidioides (Benth) S. Moore) has a compound of saponins, tannins, alkaloids and flavonoids known to be used as antioxidants. The purpose of the study to determine the activity of antioxidant and IC50 values as well as compounds contained there in and compared with Vitamin C as a positive control of antioxidant activity of sintrong leaves (Crassocephalum crepidioides (Benth) S. Moore). The research method uses DPPH attenuation method and then calculated by spectrophotometry to determine the antioxidant content. The results showed that ethanol extract of sintrong leaves has antioxidant activity that can ward off free radicals with IC50 value of 52.49 mg / ml. Conclusion there is antioxidant activity in sintrong leaf extract (Crassocephalum crepidioides (Benth) S. Moore) with IC50 value of 52.49 mg / ml (strong) but the antioxidant activity obtained greater positive control than the extract. This data is supported by the Independent T-Test the value of the thitung > ttabel, which means that there are differences in the antiokxidant activity of sintrong leaves and vitamin C. Keywords: Sintrong leaf, Free Radicals, Antioxidants, IC50.]]>
<![CDATA[TINGKAT PENGETAHUAN PASIEN TERHADAP BEYOND USE DATE (BUD) OBAT RACIKAN DI APOTEK KIMIA FARMA 180 PAHLAWAN SIDOARJO ]]>
<![CDATA[andri priyoherianto]]>;
<![CDATA[Valiandri Puspadina]]>;
<![CDATA[Merry Patrilinilla Chresna]]>
<![CDATA[ AFAMEDIS Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS ]]>
Publisher : <![CDATA[Akademi Farmasi Mitra Sehat Mandiri Sidoarjo ]]>
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<![CDATA[Abstrack Almost people usually spare medicine for supplies. If medicines not stored appropriately, medications can be exposed to varying environmental changes, making them lose their efficacy and it can be harmful to consumer’s health. for example, irrational drug use and cause drugrelated problems, including the risk of medication errors. When a product is opened, assigning a Beyond Use Date (BUD) often requires by the pharmacist to determine appropriate expired date of product. This research is a descriptive observational study. Method of data collection was carried out prospectively during April 2022. This study was conducted to patient’s knowledge level of the Beyond Use Date (BUD) of compounded drugs in Kimia Farma 180 Pahlawan Pharmacy Sidoarjo. From research conducted in April 2022, many recipes were found, both mixtures of powder, capsules, ointments, and syrups. This level of knowledge is obtained based on the results of the answers from the questionnaire sheet with a total of 10 questions to patients who come to redeem prescription medicine. Based on the results of the study, with a total of 171 respondents, it can be concluded that respondents have a level of knowledge that is included in the sufficient category with a value of 53.8%.]]>
<![CDATA[Formulasi dan Uji Mutu Fisik Sediaan Sabun Cair Ekstrak Biji Mahoni (Swietenia mahagoni L) ]]>
<![CDATA[masfah raudlotus]]>
<![CDATA[ AFAMEDIS Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS ]]>
Publisher : <![CDATA[Akademi Farmasi Mitra Sehat Mandiri Sidoarjo ]]>
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<![CDATA[Abstrack The skin is a place of excretiom, the result of the excretion is in the form of sweat that has been mixed with bacteria that can cause infection, so preparations from natural ingredients that contain antibacterial are needed. Mahogany seeds (Swietenia mahagoni L) contain alkaloids, flavonoids and saponins with the ability to inhibit antibacterial and antimicrobial inhibition. This study aims to formulate liquid soap preparations mahogany seed extract with a concentration of 0%, 20% and 50% by testing the physical quality of liquid soap preparations in the form of pH test, organoleptic test, homogeneity test, high foam test, free alkali test and stability test. The results of the evaluation of the physical quality test of liquid soap preparations with concentrations of 0%, 20% and 50% showed that the three formulations did not experience organoleptic changes, homogeneity and stability. The foam height test has a range of 111-128 mm, the pH test has a range of 8.91-9.69 and the free alkali test shows a pink color. The conclusion of this study is that liquid soap with mahagony seed extract (Swietenia mahagoni L) meets the requirements in accordancewith the requirements set by SNI 06-4085-1996.]]>
<![CDATA[PENGARUH VARIASI KONSENTRASI CROSPOVIDONE SEBAGAI SUPER DISINTEGRAN TERHADAP MUTU FISIK ORAL FAST DISSOLVING TABLET ]]>
<![CDATA[Yugo Susanto]]>
<![CDATA[ AFAMEDIS Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS ]]>
Publisher : <![CDATA[Akademi Farmasi Mitra Sehat Mandiri Sidoarjo ]]>
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<![CDATA[Ondansetron HCL is a 5-HT3 (serotonin) receptor antagonist drug which was recently introduced as an anti-vomiting drug. Ondansetron HCL is available in the form of 4 mg tablets. .The manufacture of OFDT ondansetron HCL in this formulation was to find out which results were more optimal than the different concentrations of crospovidone disintegrant with concentrations of 2%, 3%, and 4%. Oral Fast Dissolving Tablet (OFDT) are solid drug tablets that are easily disintegrated when placed on the tongue and can provide a rapid therapeutic effect. This study aims to determine the concentration of crospovidone on the physical quality of Oral Fast Dissolving Tablet. The method used in this research is experimental. Three different formulations were tested. The maximum wevelength of ondansetron HCl is 248nm. The concentrations used in the calibration of ondansetron HCl were 6 ppm, 8 ppm, 10 ppm, 12 ppm, 14 ppm, 16 ppm and 18 ppm. The results obtained were tested using SSPSS one way anova. In this study, the independent variables were several rations of crospovidone concentration, namely 2%, 3% and 4%.]]>
<![CDATA[FORMULASI DAN UJI MUTU FISIK LOTION DAUN TIN (Ficus carica L.) ]]>
<![CDATA[novia ariani]]>;
<![CDATA[Erna Fitriany]]>
<![CDATA[ AFAMEDIS Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS ]]>
Publisher : <![CDATA[Akademi Farmasi Mitra Sehat Mandiri Sidoarjo ]]>
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<![CDATA[Abstrack The fig plant is called fig in English. Most people often refer to it as a fig plant. This plant has the Latin name ficus carica L. The content of flavonoid compounds in the telang flower has the potential to be an alternative source of natural antioxidants. The purpose of this study was to determine the formulation and physical quality test of fig leaf extract lotion preparations. This research method is an experimental study of making fig leaf extract lotion by collecting the ingredients to be extracted using the maceration method with 70% ethanol solvent, formulating the extract concentration of 1%,3%,5% and evaluating the physical quality of the lotion preparation. The results obtained in the phytochemical screening are extracts containing flavonoid compounds, tannins and saponins. In the organoleptic test, homogeneity and pH have met the requirements and are safe to use for the skin.]]>
<![CDATA[PERBANDINGAN DATA PENJULAN MULTIVITAMIN DI APOTEK “X” KECAMATAN TARIK KABUPATEN SIDOARJO SEBELUM PANDEMI (PERIODE JANUARI 2020) DAN DISAAT PANDEMI (PERIODE JANUARI 2021) ]]>
<![CDATA[Ainun Mardiah]]>;
<![CDATA[M. Rizky Arif]]>
<![CDATA[ AFAMEDIS Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS ]]>
Publisher : <![CDATA[Akademi Farmasi Mitra Sehat Mandiri Sidoarjo ]]>
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<![CDATA[At the end of 2019 the world was shocked by a new virus variant, namely SARS COV2 or Covid-19, which started as an epidemic in Wuhan, China. With more and more people infected with this virus and it has spread to other countries, in 2020 WHO declared the status of the Corona Virus outbreak to be a pandemic, WHO hopes that countries in the world can take extra handling of this outbreak. Management of drug management and sales as a form of preventing the spread of the Covid-19 virus in health services as an effort to protect themselves from the transmission of the Covid-19 virus, thus making the current conditions require personal treatment through pharmacies against the Covid-19 pandemic that hit. Moreover, multivitamin drugs are needed for endurance during the pandemic. The role of pharmacies is very important in providing a very increasing drug availability. Methods: This study uses observation and in-depth interviews. In determining the number of samples using the total sampling technique. The instrument used was a data collection sheet (Observation) and interviews with pharmacist X pharmacy, Tarik sub-district. Results: the results of research on the comparison of multivitamin sales data at the "X" pharmacy, Tarik sub-district before the pandemic (January 2020) and during the pandemic (January 2021) obtained results, namely based on observational data by stating that sales of multivitamins in the pre-pandemic period (January 2020) amounted to a total of 252 with a percentage at 32%, and sales of multivitamins during a pandemic (January 2021) with a total of 529 with a percentage at 68%. This means that sales of multivitamins during the pandemic (January 2021) experienced a significant increase at 36% compared to before the pandemic (January 2020). It was proven that during the pandemic (January 2021) Pharmacy "X" in Tarik District experienced an increase in sales of around 36% compared to before the covid-19 pandemi.]]>
<![CDATA[PENGARUH STOCK OPNAME SETIAP BULA TERHADAP PENGENDALIAN OBAT ORAL KEDALUWARSA DI LOGISTIK FARMASI RSI HASANAH MUHAMMADIYAH MOJOKERTO PERIODE JANUARI – MARET 2022 ]]>
<![CDATA[Ainiy Nur Farida]]>
<![CDATA[ AFAMEDIS Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS ]]>
Publisher : <![CDATA[Akademi Farmasi Mitra Sehat Mandiri Sidoarjo ]]>
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<![CDATA[Abstrack Hasanah Muhammadiyah Mojokerto Islamic Hospital has a mission to provide health services by ensuring quality and patient safety. Pharmaceutical logistics is responsible for and supports the Hasanah Muhammadiyah Mojokerto Islamic Hospital in implementing these principles by managing pharmaceutical supplies and medical consumables (BMHP) and providing pharmaceutical services properly. The pharmacy installation of the Hasanah Muhammadiyah Mojokerto Islamic Hospital requires that drugs be managed effectively and efficiently so that there is no problem with expired drug stocks because it can cause material losses borne by the hospital. This study aims to determine the effect of monthly stock taking on the control of expired oral drugs at the pharmacy logistics of RSI Hasanah Muhammadiyah Mojokerto for the period January to March 2022. The research method used is a retrospective descriptive observational method, this study was conducted by observation, interviews, and discussions. . The results of the study showed that the stock taking carried out every month at the pharmacy logistics of the Islamic Hospital Hasanah Muhammadiyah Mojokerto had an effect on drug control efforts at the hospital. This is supported by the absence of reports of receipt of expired oral drugs that reach the patient, controlled management of oral drugs in pharmacy logistics, the percentage value of expired or lost rupiah value is very small, namely 0.08%.]]>
