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RACHMAT HIDAYAT
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Journal of Anesthesiology and Clinical Research
Published by HM Publisher
ISSN : -     EISSN : 27459497     DOI : https://doi.org/10.37275/jacr
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience
Journal of Anesthesiology and Clinical Research/JACR that focuses on anesthesiology; pain management; intensive care; emergency medicine; disaster management; pharmacology; physiology; clinical practice research; and palliative medicine.
Arjuna Subject : Kedokteran - Anesthesiology and Pain Medicine
Articles 132 Documents
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The Comparison of Plasma Cortisol Levels between 0.125% Bupivacaine and 5 mg Continuous Oxycodone in Lower Extremity Orthopedic Surgery Zulkifli; Agustina Br Haloho; Legiran; Pirma I.R.M
Journal of Anesthesiology and Clinical Research Vol. 2 No. 2 (2021): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (339.023 KB) | DOI: 10.37275/jacr.v2i2.162

Abstract

Introduction: Pain is a problem often encountered in postoperative patients. Study has shown after a procedure, 80% patients experience acute pain. This postoperative pain will affect patient’s quality of life therefore necessitating quick and proper treatment. Tissue trauma during surgery will have influence on body system, including endocrine. One of endocrine system response is cortisol secretion. Cortisol levels may be attenuated by bupivacaine and oxycodone. The aim of this study was to determine the efficacy of bupivacaine0,125% and oxycodone 5 mg on pain perception measured by cortisol in patients undergoing orthopedic surgery of the lower limb. Methods: A randomized clinical trial, double-blind study was performed at Mohammad Hoesin General Hospital in Palembang, South Sumatra, from November to May 2021. There were forty samples and divided into two groups (bupivacaine 0,125% and oxycodone 5 mg). Groups were divided by block randomization by computerized random number generator. Blinding were done by making analgesic has the same packages to prevent knowledge of which intervention is being done. Data were analyzed using independent t-test, ANOVA, Mann-Whitney and Chi Square with SPSS version 22.0. Results: There were no statistically significant differences between the two groups on age, gender, body mass index and duration of surgery. In bupivacaine group, cortisol level decreased from 12.94±6.99 µg/dl to 11.32±5.42 µg/dl meanwhile oxycodone group cortisol levels increased from 11.81±8.47 µg/dl to 11.82±7.56 µg/dl. There were no significant difference between two groups relating to cortisol levels. Conclusions: No significant difference was found on administration of bupivacaine 0,125% and oxycodone 5 mg as epidural analgesia on cortisol level in postoperative orthopedic surgery of the lower limb patient.
Correlation of SOFA Score and Hormone Value for Predicting 28-days Mortality for Septic Patients Zulkifli; Agustina Br Haloho; Ziske Maritska; Dipta Anggara
Journal of Anesthesiology and Clinical Research Vol. 2 No. 2 (2021): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (183.905 KB) | DOI: 10.37275/jacr.v2i2.163

Abstract

Introduction. Sepsis is a group of symptoms of organ dysfunction that can be life-threatening because of dysregulation of body response toward ongoing infection. Organ dysfunction in sepsis can be measured by Sequential Organ Failure Assessment (SOFA) and T3 hormone. The study was aimed to identify the correlation of T3 in predicting mortality of 28 days patients in Intensive Care Unit RSMH Palembang. Method. This study design is cohort prospective. The inclusion criteria consist of a patient diagnosed with sepsis and septic shock in the Intensive Care Unit, 18-64 years old. Patients with a history of thyroid disease, pregnant or post-pregnancy, the patient admitted in referral from other hospitals, and patients with a history of psychiatry medication and thyroid medication were excluded. Data collected is the patient whose stay in Intensive Care Unit RSMH followed in 28 days from January 2021 until the sample was fulfilled (39 samples). Analyzing data was SPSS version 23 with chi-square analysis and Fisher's Exact to identify the relationship. Pearson correlation to identify correlation coefficient, and Medical application to measure AUC, cutoff value, sensitivity, and specificity. Result. The result showed that age (p=0,445). gender (p=1,00), need of ICU (p=0,228), isolation-nonisolation ward (p=0,437) didn't have any significant relationship toward mortality. SOFA score correlate statistically with positive correlation and medium strength (0,633) toward mortality of sepsis patient (p=0,000). T3 hormon correlate positively with medium strength (0,514) toward mortality of sepsis patient (p=0,001). T3 hormone toward SOFA correlate negatively (-0,365) with significant correlation (p=0,22). T3 hormone has AUC 0,291 with sensitivity 3,3% and specificity 67,7%. Conclusion. T3 hormone has a significant negative correlation to mortality in sepsis patients but cannot be used to predict mortality with a low AUC value (0,291).
Genicular Nerve Radiofrequency Ablation and Dual Subsartorial Block for Chronic Knee Pain Post Total Knee Replacement: A Case Report Aidyl Fitrisyah; Stevanus Eliansyah Handrawan; Nurlaili Maya Ramadhanty
Journal of Anesthesiology and Clinical Research Vol. 2 No. 2 (2021): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.919 KB) | DOI: 10.37275/jacr.v2i2.164

Abstract

Introduction. Chronic pain defines as pain persisting for three months or longer, chronic post-surgical pain can affect all dimensions of health-related quality of life, and is associated with functional limitations. treatment of chronic pain after total knee replacement is challenging, and evaluation of combined treatments and individually targeted treatments matched to patient characteristic. Genicular nerve block radiofrequency ablation is a safe and effective therapeutic procedure for pain associated with chronic pain due to knee osteoarthritis, and the evolution of newer regional analgesia techniques aids in reducing postoperative pain Dual Subsartorial Block (DSB) as a procedure specific, post total knee replacemet. historically there has been a reliance on using a pain-spesific assessment tools Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Case Presentation. A 55-year old woman admitted she had pain on bilateral knee, the knee pain had affected her daily living, she was diagnosed with chronic knee pain post TKR because of osteoarthritis genu bilateral, the patient was planning genicular nerve radiofrequency ablation and dual subsartorial block, from the examination we found that numeric rating scale was 6 (moderate pain) with WOMAC score 76, before the procedure the patients are examined through radiology for any deformity in the knee. The genicular nerve radiofrequency ablation under ultrasound guidance on bonylandmark, resulting anesthesia of the anterior compartment of the knee, and dual subsartorial block that cover almost all the innervations of pain generating component of the anterior and posterior knee joint involved in TKR surgery. After the procedure we reevaluated the pain score using NRS was 2 (mild pain), and with WOMAC Score 19. Conclusion. Treatment of chronic pain post total knee replacemet was challenging, targeted treatment may ameliorate the pain and prevent long term disability.
Burnout Among ENT Residents During Covid-19 Pandemic: What Are The Contributing Factors? Andrey Dwi Anandya; Abla Ghanie; Ahmad Hifni
Journal of Anesthesiology and Clinical Research Vol. 2 No. 2 (2021): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.806 KB) | DOI: 10.37275/jacr.v2i2.165

Abstract

Introduction. Resident doctors are susceptible to burnout syndrome, which are the combination of physical and psychological fatigue, that may affect their performance. Long-term pandemic of Covid-19 may also contribute to increase the severity of burnout among residents doctor, might be because the increasing of work time and effort to treat the patients during the time while maintaining prevention against the possible exposure that may harm themselves. This study was aimed to evaluate burnout prevalence among ENT (Ear-Nose-Throat) medical residents in Covid-19 pandemic, and its relation to certain factors of demographic and wellness. Methods. Thirty ENT medical residents of Medical Faculty of Sriwijaya University were enrolled as study population. Burnout was measured by Copenhagen Burnout Inventory (CBI) and divided by three parameters (personal,work-related, patient-related). Results. Among 30 ENT resident doctors at Rumah Sakit Moh. Hoesin, the mean level of personal burnout was 53.056 (SD 17.125), work-related burnout was 47.975 (SD 17.663), and patient-related burnout was 34.861 (SD 20.746). Conclusion. Marriage, female gender, and inadequacy of PPE may contribute to the development of burnout. The burnout among resident doctors is a serious matter regarding their role as a frontline doctor during the pandemic era, because it may affect not only their performance at work, but toward their life as well.
Perioperative Management in Patients with Temporary Pacemaker Who Underwent Craniotomy in Prone Position Purwoko; Handayu Ganitafuri
Journal of Anesthesiology and Clinical Research Vol. 3 No. 1 (2022): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/jacr.v3i1.205

Abstract

Introduction: As the incidence of the need for a pacemaker increases, an anesthesiologist may encounter patients with pacemakers who need surgery other than the heart. With enough knowledge, the outcome of patients with pacemakers undergoing procedures other than cardiac surgery can be optimized with the hope that mortality and morbidity can be avoided. Case presentation: Male, 42 years old, with Temporary Pacemaker (TPM), programmed for evacuation craniotomy and decompression. The patient had Intracranial Hemorrhage (ICH) after the Percutaneous Intra Arterial Thrombolysis (PIAT) procedure 2 days earlier. The patient was stable during the operation, which lasted for 3 hours in the prone position. Conclusion: The perioperative strategy should be customized based on the procedure, the needs and values of the patient, and the device attached. The primary focus of perioperative management in patients who underwent surgery is minimizing the possibility of electromagnetic interference (EMI).
Obesity Hypoventilation Syndrome Harles Sitompul; Aura Ihsaniar
Journal of Anesthesiology and Clinical Research Vol. 3 No. 1 (2022): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/jacr.v3i1.206

Abstract

Obesity Hypoventilation Syndrome or commonly abbreviated as OHS, is a respiratory disorder that often occurs in patients characterized by decreased oxygen levels and increased carbon dioxide in the blood. Based on the criteria of the World Health Organization (WHO), the definition of obesity is if the BMI is equal to or greater than 30 kg/m2. The classification of obesity is BMI 30-34.9 kg/m2, 35-39.9 kg/m2 and > 40 kg/m2. The pathophysiology of OHS is still not fully known with certainty. Severe obesity causes an increase in the burden on the respiratory system, weakness of the respiratory muscles, leptin resistance, and respiratory disturbances during sleep, causing a decrease in the sensitivity of the ventilation center response, which can lead to hypoventilation and hypercapnia. Basically, there are six points of OHS management, including a weight loss program, oxygen therapy, positive pressure ventilation, pharmacotherapy, tracheostomy, and management of OHS complications.
Perioperative Management of Tonsillectomy in Pediatrics with Tetralogy of Fallot Rizqi Ahmad Nur Dwiyono; Paramita Putri Hapsari
Journal of Anesthesiology and Clinical Research Vol. 3 No. 1 (2022): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/jacr.v3i1.216

Abstract

Introduction. Tetralogy of Fallot (TOF) is a cyanotic congenital heart disease that includes ventricular septal defect, aortic overriding, infundibular stenosis, and Right Ventricle Hypertrophy (RVH). Perioperative management includes preoperative management, intraoperative anesthesia, and post-operative and potential problem management. Case presentation. We report a -8-year-old-girl with congenital heart disease TOF planned for tonsillectomy and adenoidectomy. The patient weighs 18 kilograms, has a blood pressure of 96/55 mmHg, pulse rate of 104 times per minute, respiratory rate 24 times per minute, and oxygen saturation of 74-79% supine position with room air. We find ejection systolic murmur at SIC 4/6 left parasternal and clubbing fingers-on physical examination. Laboratory preoperation shown Hb value 22.9; Hct : 70; AL : 11.2; AT : 281; AE : 8.58. We pre-medicate with ondansetron, dexamethasone, and sedation in the transit room with ketamine and midazolam. Induction by fentanyl and rocuronium to facilitate endotracheal intubation. Postoperatively, the patient was transferred to the PICU with an ET in a tube. She is monitored for a post-operative complications such as active bleeding to hyper cyanotic and performed extubation less than 24 hours after surgery. Conclusion. Anesthetic goals in this patient are to maintain or slightly increase the Systemic Vascular Resistance, minimize Pulmonary Vascular Resistance dan provide mild cardiac depression.
Perianal Block for Open Hemorrhoidectomy: A Case Series Muhammad Iqbal; Dewi Larasati Riono; Andi Husni Tanra; Yudi Gumara
Journal of Anesthesiology and Clinical Research Vol. 3 No. 1 (2022): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/jacr.v3i1.224

Abstract

Introduction: Hemorrhoidectomy is one of the most common anorectal surgeries performed in a surgical room or ambulatory clinic. The procedure is linked to severe postoperative pain. Both general and regional anesthesia with spinal anesthesia is used in anorectal surgery. However, these predominantly used anesthesia methods leave postoperative side effects of nausea, vomitus, urinary retention, headache, dizziness, back pain, prolonged inferior muscle weakness, and the level of postoperative pain after the anesthesia wears off. Case presentation: Three cases of severe hemorrhoids were reported, and they underwent open hemorrhoidectomy with a perianal block. Postoperatively, all cases reported no side effects, minimal level of pain, and faster recovery. Recently, the perianal block has been used to curtail the side effects. Conclusion: Perianal block is performed by infiltrating the inferior rectal nerves innervating the anus and sphincter muscle. Sedation is sometimes performed prior to injection of the anesthetic block. This technique is considered safe and effective for hemorrhoidectomy.
Potential of Activated Platelet-Rich Plasma Against Osteoarthritis: In Vivo Study Rachmat Hidayat; Patricia Wulandari
Journal of Anesthesiology and Clinical Research Vol. 3 No. 1 (2022): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/jacr.v3i1.241

Abstract

Introduction: Osteoarthritis (OA) is a disorder that causes a decrease in the quality of life in elderly patients. The current treatment is only symptomatic in reducing inflammation. This study is one of the exploratory studies to examine the potential of platelet-rich plasma (PRP) in optimizing the improvement of OA patients through the inhibition of inflammatory signals in joint tissue in vivo. Methods: This study is an experimental study with a post-test-only approach with a control group design. A total of 30 rats (Rattus norvegicus) Wistar strain was included in this study and met the inclusion criteria in the form of the male gender, weight between 150-200 grams, and age 8-10 weeks. The rats were divided into 3 groups, namely the group that was not induced by OA and not given PRP (P1), the OA group and given 50 uL saline injection (P2), the OA group and given PRP 50 uL (P3), the treatment was carried out once a week for 4 weeks. Results: The results showed that the P3 group that was treated with platelet-rich plasma showed a significant decrease in interleukin-1ß levels when compared to the P2 group that was induced by OA but was only treated with saline (p<0.05). Conclusion: Platelet-rich plasma has the potential as a biological agent against osteoarthritis in an in vivo study.
Pharmacological Therapy in Sub-Acute Postherpetic Neuralgia Patients: A Case Report Alamsyah Irwan; Andi Muhammad Takdir Musba
Journal of Anesthesiology and Clinical Research Vol. 3 No. 2 (2022): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/jacr.v3i2.248

Abstract

Introduction: Herpes zoster is caused by the reactivation of the varicella-zoster virus. Post-herpetic neuralgia (PHN) is pain due to a zoster that persists 1 month after vesicle development. Usually, the prognosis is good, but some patients continue to suffer from long-term pain. The goal of PHN therapy is to reduce pain and improve quality of life. Antiepileptic drugs and tricyclic antidepressants are the first choices. Case presentation: A 32-year-old man presented with complaints of left-sided headache radiating like electricity to the left eyelid for ± 6 weeks, sudden spikes of nails, numbness/cramping sensation, and pain when touched (allodynia), and hypoesthesia. His previous medical history was herpes zoster, and he received acyclovir and symptomatic therapy such as paracetamol, mefenamic acid, dexamethasone, and cetirizine. The patient presented with a 6-7/10 visual analog scale (VAS) and was diagnosed with subacute post-herpetic neuralgia. The patient received Lyrica (Pregabalin) 50 mg 2 times a day 1 tablet, amitriptyline 10 mg once a day 1 tablet, Ultracet (Tramadol 37.5 mg + paracetamol 375 mg) 3 times a day 1 tablet. After the 14th day, the patient's VAS was reduced to 2/10, but side effects occurred in the form of dry lips and frequent sleepiness, and continued treatment with only Amitriptyline 10 mg/day. Conclusion: Rapid therapy for PHN provides prevention of refractory pain, making it difficult to provide adequate therapy. Giving first-line therapy in subacute PHN using amitriptyline, pregabalin, and tramadol agents have a very good effect in overcoming pain in subacute PHN, but it is necessary to monitor the side effects that occur due to potentiation of these three drugs.

Page 3 of 14 | Total Record : 132

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