cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Slamet Supriadi
Contact Email
slamet.supriadi@i3l.ac.id
Phone
+622129567888
Journal Mail Official
ijls@i3l.ac.id
Editorial Address
Indonesian Journal of Life Sciences LPPM - Indonesia International Institute for Life Sciences (i3L) Jl. Pulomas Barat Kav. 88, Jakarta Timur, 13210 Indonesia
Location
Kota adm. jakarta timur,
Dki jakarta
INDONESIA
Indonesian Journal of Life Sciences
Published by Indonesia International Institute for Life Sciences
ISSN : -     EISSN : 26560682     DOI : http://doi.org/10.54250/ijls
Core Subject : Health, Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Medicine & Pharmacology
The Indonesian Journal of Life Sciences (IJLS) is a journal published by Indonesia International Institute for Life Sciences Press (i3L Press). IJLS is a scientific journal contains original research articles, review articles, and short communication covering all aspects in life sciences. This journal provides immediate open access to its content on the principle that making research freely available to the public to support a greater global exchange of knowledge. Readers can view abstracts and download full-text articles (PDF) free at any cost. All manuscripts submitted to the Indonesian Journal of Life Sciences will be screened for plagiarism and blind peer-reviewed to present valuable and authentic findings in life sciences. Authors with original, clearly analyzed, and logically interpreted research result in the scope of food innovation and nutrition, bio-products and services for sustainable society, information technology in life sciences, as well as health and well-being are very welcome to submit their articles. Every article issued to the editorial of the Indonesian Journal of Life Sciences is free of charge including the cost of repairing the article. IJLS is published bianually on March and September. Manuscripts are accepted on a continuous basis and the submisison is opened through the year.
Arjuna Subject : Imunologi dan Mikrobiologi (semua kategori) - Mikrobiologi dan Bioteknologi Terapan
Articles 5 Documents
 1 
Search results for , issue "2020: IJLS Vol 02 No .01" : 5 Documents clear
Cytotoxicity Evaluation of Bacteria Extract Isolated from Indonesia Sheep Manures and Fungal Fruiting Body Hartiadi, Leonny Yulita; Winiati, Immaculata Titis; -, samirah -; Gomez, Cristina
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .01
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1012.073 KB) | DOI: 10.54250/ijls.v2i1.31

Abstract

Introduction: Cancer is one of the leading cause of death worldwide. Chemotherapy remains the most widely used approach to treat cancer. However, due to the lack of specificity, drug resistance, and undesirable side effects, the discovery of novel anticancer drugs is still a priority in cancer research. Bacteria are one of the major contributors for anticancer compounds as bacteria are able to produce secondary metabolites which may have cytotoxic activity. Method: A literature study was conducted to identify the isolates in i3L-USAID bacteria database that were potential candidates for novel anticancer drugs. The selected bacteria were cultured and their secondary metabolites were extracted. Cytotoxic activity of the extracts was assessed through morphological observation and MTT assay on HeLa and 3T3 fibroblast cell lines. Results: Aneurinibacillus sp. and Ochrobactrum sp. were selected. Ochrobactrum sp. extract significantly suppressed the growth of HeLa cells at 1000 µg/ml (p < 0.05) while it did not have any effect on 3T3 cells. Despite able to suppress the HeLa cell proliferation, Aneurinibacillus sp. extract significantly enhanced the growth of 3T3 fibroblast at the 1000 µg/ml (p < 0.05). The cytotoxicity activity was corroborated by cell death observed on HeLa cells treated with high concentrations of the extracts Conclusion: Secondary metabolites from Aneurinibacillus sp. and Ochrobactrum sp. could only exert cytotoxic effect at high concentration which is unfavourable for anticancer compounds. Although the extracts resulted in a reduction of HeLa cells proliferation, the extracts did not inhibit proliferation of 3T3, suggesting selectivity for non-tumorigenic over tumorigenic cells.
Botanical Aspects, Phytochemicals and Health Benefits of Andaliman (Zanthoxylum acanthopodium) Natasutedja, Alfredo Oktavianto; Lumbantobing, Erika; Josephine, Emita; Carol, Lioni; Junaedi, Decky Indrawan; Normasiwi, Suluh; Putra, Agus Budiawan Naro
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .01
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (281.305 KB) | DOI: 10.54250/ijls.v2i1.32

Abstract

Andaliman (Zanthoxylum acanthopodium) is a specialty spice widely found in the Provinces of North Sumatra and Aceh, Indonesia. The fruit is usually used by Batak people in North Sumatra as a food ingredient to cook Batak’s cuisine such as arsik, tombur, and naniura. It is also used as one of the ingredients to make Indonesian spicy sauce called sambal. Andaliman fruit is reported to eliminate the undesirable smell in fish and raw meat. Moreover, it could also reduce total volatile base nitrogen content in fish which helps to prevent spoilage. Furthermore, andaliman has been reported to contain bioactive compounds which act as antioxidant, antimicrobial, anti-inflammatory, anti-aging, anti-acne, and anti-halitosis effects. This review focuses on the botanical aspects of and health potential exhibited by andaliman.
Inulin from Several Tubers Available in Indonesia and the Growth of Gut Microbiota Crespo, Ivan; Arindra, Augusto; Lualdi, Jessica Tashia; Rimba, Phoebe Anadita; Putra, Agus Budiawan Naro; Rahardja, Ritchie
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .01
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1023.052 KB) | DOI: 10.54250/ijls.v2i1.33

Abstract

Indonesia has many types of tubers, some of them are gembolo tuber (Dioscorea bulbifera), lesser yam (Dioscorea esculenta), yam bean (Pachyrhizus erosus), and dahlia tuber (Dahlia pinnata); which are the sources of prebiotics. The term of prebiotics has been used since 1995 to describe the non-digestible components in food that positively alter gut microbiota activity and exhibit beneficial properties to the human body. One of the prebiotics that can be found in tubers is inulin. This review was aimed to compare inulin content in the above-mentioned tubers and their roles towards the growth of gut microbiota. Library searches using Semantic Scholar database was done. Findings showed that gembolo tuber contains the highest inulin content, followed by lesser yam, dahlia tuber, and yam bean. Moreover, inulin increases the population of Lactobacillus, Bifidobacterium, and Bacteroides while inhibits the growth of Escherichia coli and reduce the growth of Clostridium.
Meta-Analysis: Effectiveness of SSRIs vs SSRIs in conjunction with CBT in treating depression in young adolescents Kresnia, Gabriele Mustika; Hasuki, Winda; Pradana ratnasari, Nanda Rizqia
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .01
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (870.43 KB) | DOI: 10.54250/ijls.v2i1.35

Abstract

Objective: To compare the efficacy of SSRI medication alone and SSRI+CBT combined. Methods: NCBI Pubmed, DARE, CSDR and NGC were searched October-November 2019. The population size, as well as the base and endpoint CGAS mean and standard deviation from the three studies included, are recorded. Statistical analysis was done in RStudio with the "meta" package. Results: For the SSRI only, the effect size was -1.82 with a 95% confidence interval between -2.28 and -1.37. For the SSRI and CBT combined, the effect size was -1.68 with a 95% confidence interval between -2.39 and -0.98. The effect size for both SSRI and SSRI + CBT didn't cross the null effect line, but the heterogeneity exceeds 50%. The result for the comparison of post SSRI vs. SSRI + CBT showed the effect size of -0.05 with a 95% confidence interval between -0.23 and 0.12. The size effect did cross the null effect line, but the heterogeneity was less than 50%. Conclusion: Both methods were shown to be effective. However, due to statistical inconsistencies, it couldn’t be concluded whether the combination of SSRI and CBT is better than treatment with SSRI alone.
What do T cells see in SARS-CoV2? Gustiananda, Marsia
Indonesian Journal of Life Sciences 2020: IJLS Vol 02 No .01
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (875.758 KB) | DOI: 10.54250/ijls.v2i1.36

Abstract

The current epidemic caused by a novel coronavirus SARS-CoV2 as well as two previously documented pandemic caused by SARS-CoV and MERS-CoV imposes that a spillover of an animal coronavirus to humans is a continuous threat. The zoonotic nature of the infection contributes to the unpredictability of the pandemic. In such situations, the availability of the ‘off the shelf’ vaccines that target the conserved region of the coronavirus might help in preventing the spread of the diseases. Therefore, efforts to generate such vaccines should be considered as a priority. The whole genome of SARS-CoV2 is readily available in the public database one month after the first case was identified. The platform technology known as the “genome to vaccine” approach would provide useful start to identify parts of the virus proteome which can be the candidate for vaccine components. This study used an immunoinformatic approach to identify T cell epitopes from SARS-CoV2 ORF1ab polyprotein in an attempt to design a genome-derived epitope-based universal coronavirus vaccine.

Page 1 of 1 | Total Record : 5

 1 

Filter by Year

2020 2020


Reset
Filter By Issues
All Issue 2025: IJLS Vol 07 No.02 2024: IJLS Vol 06 No.02 2024: IJLS Vol 06 No.01 2023: IJLS Vol 05 No .02 2023: IJLS Vol 05 No .01 2022: IJLS Vol 04 No .02 2022: IJLS Vol 04 No .01 2021: IJLS Vol 03 No .02 2021: IJLS Vol 03 No .01 2020: IJLS Vol 02 No .02 2020: IJLS Vol 02 No .01 2019: IJLS Vol 01 No .02 2019: IJLS Vol 01 No .01 More Issue