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Murdani Abdullah
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Divisi Gastroenterologi, Departemen Ilmu Penyakit Dalam, FKUI/RSUPN Dr. Cipto Mangunkusumo, Jl. Diponegoro No. 71 Jakarta 10430 Indonesia
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INDONESIA
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Published by The Indonesian Society for Digestive Endoscopy
ISSN : 14114801     EISSN : 23028181     DOI : -
Core Subject : Health,
Medicine & Pharmacology
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy is an academic journal which has been published since 2000 and owned by 3 Societies: The Indonesian Society of Gastroenterology; Indonesian Association for the Study of the Liver; The Indonesian Society for Digestive Endoscopy. The aim of our journal is to advance knowledge in Gastroenterology, Hepatology, and Digestive Endoscopy fields. We welcome authors for original articles, review articles, and case reports in the fields of Gastroenterology, Hepatology, and Digestive Endoscopy.
Arjuna Subject : Kedokteran - Ilmu Pencernaan
Articles 7 Documents
 1 
Search results for , issue "VOLUME 2, NUMBER 3, December 2001" : 7 Documents clear
Current Treatment of Gastroesophageal-Esophagitis Reflux Disease Chudahman Manan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 2, NUMBER 3, December 2001
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/23200131-34

Abstract

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The Role of Gastric Acidity and Lower Esophageal Sphincter Tone on Esophagitis in Patients with Dyspepsia Syafruddin AR Lelosutan; Chudahman Manan; Busjra M. Nur
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 2, NUMBER 3, December 2001
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2320016-11

Abstract

Background: Esophagitis implies an organic damage of the esophagus due to several pathophysiologic factors, predominantly: (1) degree of gastric acid secretion (gastric pH), whereabouts are rapidly or slowly to be mucosal breaks onto esophagus were under the influenced by: (a) gastric pH £ 4 and (b) the contact of gastric acid into esophageal mucosal. (2) Lower esophageal sphincter (LES) as a important factor for antireflux mechanisms, which antireflux mechanism cannot serve as a barrier system whenever tone of LES comes down until £ 10 mmHg that causes feeble resting LES pressure. Esophageal injuries are recognized endoscopically by the presence of the Savary-Miller’s classification (1985), but there are not definitely which ones principally to pathophysiologic factor.Methods: This was a consecutive non-random sampling cross sectional study. Thirty subject from 127 patients with dyspepsia undergoing elective upper-endoscopic examination with collecting of the gastric juice and biopsies of lower esophageal mucosal, also esophageal manometric examination. Before that, clinical inclusive and exclusive criterias until laboratory examination were performed. Significant interval was 95%. Analyzing data with Fisher’s Exact Test One-Tail to correlate between gastric pH and hypotonic LES into esophagitis. Results: Esophagitis prevalence was 22.8%. Fisher’s Exact Test One-Tail to correlate esophagitis with gastric pH £ 4 was significant (p=0.013798), but with hypotonic LES (tones of LES £ 10 mmHg) was not (p=0.60269). The combined roles of gastric pH and tones of LES into esophagitis are included: (1) Frequency of roles of pH £ 4 and hypotonic LES are 48.2%. (2) Frequency of role of pH £ 4 without hypotonic of LES are 33.3%. (3) Frequency of role of hypotonic LES without pH £ 4 are 11.1% and (4) Frequency of esophagitis without roles of pH £ 4 and hypotonic of LES are 7.4%. Conclusions: The sum of gastric pH £ 4 and hypotonic of LES together are more than each separate factor. Onto statistically was significant between esophagitis and gastric pH, but there is no correlation with tones of LES. So, gastric pH plays a more important role than LES.    Key words: gastric pH, tones of LES, roles of pH and tones of LES, esophagitis
Endogenous Endotoxemia in Patients with Liver Cirrhosis Andri Sanityoso Sulaiman
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 2, NUMBER 3, December 2001
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/23200112-21

Abstract

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The Efficacy of Low Dose Captopril Adjuvant for Natriuresis in Patient with Liver Cirrhosis with Ascites Who Have Received Furosemide and Spironolacton Suyatmi Suyatmi; Bantar Suntoko; F. Sumanto; Hirlan Hirlan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 2, NUMBER 3, December 2001
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2320011-5

Abstract

Background: The ideal therapy for ascites in liver cirrhosis is a low sodium diet and a combination of furosemide and spironolacton. However, this still sometimes does not produce satisfactory Results, even after increasing the dose of the diuretic. Such failure occurs due to the influence of the Renin Angiotensin Aldosterone (RAA) system. Low doses of ACE inhibitors (captopril) should improve renal blood flow and increase filtration at the glomeruli, thus increasing natriuresis without causing haemodynamic imbalance. Study aim: To discover the natriuretic and diuretic effects of low dose captopril adjuvant in patients with liver cirrhosis who have received furosemide and spironolacton by measuring urinary sodium and 24-hour urine output. Materials and method: This study was conducted on in- and out- patients with liver cirrhosis and Ascites at the Dr. Kariadi Central Public Hospital, Semarang, who met the inclusion and exclusion criteria. The study took place from June 1st, 1997 to March 31st, 1998, and included 40 cases of liver cirrhosis with ascites. Study design: Open comparative randomized clinical trial with permuted blocks. All of the patients received a low fat diet, 40 mg of furosemide, 3x50 mg of spironolacton for 2 weeks, and patients with a urinary sodium level was below 80 mEq/L were randomized into two groups: group A receiving 3 x 6.25 mg of captopril, and group B receiving standard therapy.  Results:  Variable            Pre- treatment       Post – treatment      p  Group A : Urinary sodium level (meq/L)   65.450 ± 16.577       109.950 ± 49.109     0.001 24-hour urine output (cc)     1138.750 ± 480.438     1381.250 ± 394.441    0.004 Group B: Urinary sodium level (meq/L)  68.30 ± 12.85         91.750 ± 64.04      0.103 24-hour urine output (cc)       1390 ± 448.27        1392.50 ± 713.46     0.988   The pre- and post- treatment Results for Group A were significantly different. The pre- and post- treatment Results for Group B were not significantly different. Conclusion: Low dose (3 x 6.25 mg) captopril adjuvant in patients with liver cirrhosis and ascites who have received standard doses of furosemide and spironolacton could increase natriuresis and diuresis without causing haemodynamic imbalance.    Key words: Captopril, liver cirrhosis, ascites
Development and Application of Endoscopy K L Goh
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 2, NUMBER 3, December 2001
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/23200122-24

Abstract

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Achalasia Carcinoma Sequence Dadang Makmun
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 2, NUMBER 3, December 2001
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/23200128-30

Abstract

We report a case of carcinoma of the esophagus in a 58 years old woman with achalasia, who has been diagnosed since 30 years ago, which initiated by surgical treatment (myotomy) and the symptoms recurred since 3 years ago. According to the progress of the disease, malignancy was strongly suspected due to prolonged stasis and mucosal irritation caused by achalasia (achalasia carcinoma sequence). Because of these contributing factors for the development of serious complications such as malignancy, the diagnosis of achalasia must be systematically diagnosed and treated agressively. Surveillance endoscopy in patients with achalasia should be performed every 1-2 years.    Key words: achalasia carcinoma sequence, surveillance endoscopy
Diagnostic Problem and Management of Intestinal Tuberculosis Ryan Ranitya; Ari Fahrial Syam; Marcellus S Kolopaking; Vera Yoewono
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 2, NUMBER 3, December 2001
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/23200125-27

Abstract

Intestinal tuberculosis, without any evidence of pulmonary or tuberculous infection elsewhere in the body, is still a rare case. Sometimes it is very difficult to make an early and prompt diagnosis for this, because clinical manifestations are varied, unspecific, and mimic other diseases. Examinations, including chest x-ray, tuberculin test, acid-fast stained smear, endoscopic and histological findings may still be inconclusive. Thus, therapeutic trials of anti- tuberculous drugs are advised. We report a case of intestinal tuberculosis with a chief clinical manifestation of chronic diarrhea. There was no evidence of tuberculous infection elsewhere in the body Endoscopic appearance and histological findings were atypical and unspecific. The patient was given anti- tuberculous drugs and responded very well clinically within 2 weeks.    Keywords: Intestinal tuberculosis, difficult diagnosis, management

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