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UPT Publikasi Ilmiah, Universitas Islam Bandung. Jl. Tamansari No. 20, Bandung 40116, Indonesia, Tlp +62 22 420 3368, +62 22 426 3895 ext. 6891
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Bandung Conference Series: Pharmacy
Published by Universitas Islam Bandung
ISSN : -     EISSN : 28282116     DOI : https://doi.org/10.29313/bcsp.v2i2
Core Subject : Health, Science,
Chemistry Medicine & Pharmacology Public Health
Bandung Conference Series: Pharmacy (BCSP) menerbitkan artikel penelitian akademik tentang kajian teoritis dan terapan serta berfokus pada Farmasi dengan ruang lingkup Airlock system Kanker, Alcohol, Antelmintik, Antigastritis drugs, Antioksidan, Artemia franciscana, Ascaris suum, Cacing babi (Ascaris suum Goeze), Contact Bioautography TLC, Daun cincau hijau (Cyclea barbata Miers), Daun kelor (Moringa oleifera Lam), Diabetes mellitus, DPPH Flavonoid, Fenilpropanolamin, Fermentasi, Flavonoid, Flavonol,Iles-iles, Isolasi, Lichen, Malassezia furfur, Metode Brine Shrimp Lethality Test (BSLT), Obat antidiabetes (OAD) Propionibacterium acnes, Obat tradisional, Parkia Speciosa Antibakteri, Pektin, Propionibacterium Acnes, Pseudoefedrin, Saccharomyces Cerevisiae, Spektrofotometri uv sinar tampak, Staphylococcus epidermidis, uji aktivitas antibakteri, Uji sitotoksik, Usnea baileyi. Prosiding ini diterbitkan oleh UPT Publikasi Ilmiah Unisba. Artikel yang dikirimkan ke prosiding ini akan diproses secara online dan menggunakan double blind review minimal oleh dua orang mitra bebestari.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 1 Documents
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Search results for , issue "543 - 552" : 1 Documents clear
Karakterisasi Simplisia dan Ekstrak Daun Kemangi dari Daerah Cihanjuang Kabupaten Bandung Bagas Hadi Panoreh; Siti Hazar; Bambang Tri Laksono
Bandung Conference Series: Pharmacy 543 - 552
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsp.v6i2.25180

Abstract

Abstract. Diabetes mellitus is a chronic metabolic disease that often causes skin wound complications with delayed healing due to hyperglycemia and chronic inflammation, necessitating standardized and accessible medicinal raw materials. Basil (Ocimum basilicum L.) is known to be rich in secondary metabolites with potential wound-healing properties. This study aimed to characterize the specific and non-specific parameters of basil leaf simplicia and ethanol extract from Cihanjuang, West Bandung Regency, as a candidate raw material for wound-healing preparations. The study was conducted experimentally in the laboratory using simplicia and extract obtained through maceration with 96% ethanol. Evaluations included specific parameters (organoleptic, water-soluble, and ethanol-soluble extract content) and non-specific parameters (water content, drying shrinkage, total ash, acid-insoluble ash, and specific gravity), along with phytochemical screening. The results showed that the simplicia and extract met most requirements of the Indonesian Herbal Pharmacopoeia, with water-soluble extract content of 18.67%, ethanol-soluble extract content of 9.96%, water content of 5.25%, drying shrinkage of 5.89%. Phytochemical screening confirmed the presence of alkaloids, flavonoids, saponins, tannins, terpenoids, as well as monoterpenes and sesquiterpenes. However, total ash and acid-insoluble ash content exceeded the limits, presumably due to soil and dust contamination. Thus, basil from Cihanjuang shows potential as a standardized raw material, although improvements in the washing process and further in vivo activity tests are recommended. Abstrak. Diabetes melitus merupakan penyakit metabolik kronis yang sering menyebabkan komplikasi luka kulit dengan proses penyembuhan tertunda akibat hiperglikemia dan inflamasi kronis, sehingga diperlukan bahan baku obat yang terstandar dan mudah diakses. Tanaman kemangi (Ocimum basilicum L.) dikenal kaya akan metabolit sekunder yang berpotensi mendukung penyembuhan luka. Penelitian ini bertujuan untuk mengkarakterisasi parameter spesifik dan non spesifik simplisia serta ekstrak etanol daun kemangi asal Cihanjuang, Kabupaten Bandung Barat, sebagai kandidat bahan baku sediaan penyembuh luka. Penelitian dilakukan secara eksperimental di laboratorium, dengan objek berupa simplisia dan ekstrak yang diperoleh melalui metode maserasi menggunakan pelarut etanol 96%. Pengujian meliputi parameter spesifik (organoleptik, kadar sari larut air dan etanol) dan non spesifik (kadar air, susut pengeringan, kadar abu total, kadar abu tidak larut asam), serta skrining fitokimia. Hasil penelitian menunjukkan bahwa simplisia dan ekstrak memenuhi sebagian besar persyaratan Farmakope Herbal Indonesia, dengan kadar sari larut air 18,67%, kadar sari larut etanol 9,96%, kadar air 5,25%, susut pengeringan 5,89%. Skrining fitokimia mengonfirmasi keberadaan alkaloid, flavonoid, saponin, tanin, terpenoid, serta monoterpen dan seskuiterpen. Namun, kadar abu total dan abu tidak larut asam masih melebihi batas, yang diduga berasal dari kontaminasi tanah dan debu. Dengan demikian, daun kemangi asal Cihanjuang berpotensi dikembangkan sebagai bahan baku terstandar dan uji aktivitas lanjutan secara in vivo.

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