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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 1,092 Documents
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Adsorption of 1- (2--Hydroxy - 4--Nitrophenyl azo)-2- Napthol Dye onto the Cement Kiln Dust (CKD) Nemah Sahib Mohammed Hussian
Journal of Global Pharma Technology Volume 10 Issue 01: (2018) Jan. 2018
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Abstract

The adsorption of 1-(2¯- Hydroxy-4¯-nitrophenyl azo) -2-naphthol dye onto the Cement Kiln Dust (CKD) was studied in the temperature range 298-328K. The sorption process was examined in terms of its equilibria and kinetics. Batch adsorption experiments were conducted to evaluate the percentage removal of 1-(2--Hydroxy -4- - nitrophenyl azo)-2-napthol onto CKD waste at operation conditions of sorbate concentration, pH, contact time, sorbent dose. Time-dependent experiments for the removal efficiency required a shortest contact time, i.e , binding to the CKD was rapid and occurred within 25 min. Adsorption isotherms equations were tested for all of Langmuir, Freundlich, Temkin,3 Dobinin-Radushvich, and Elovich. The equilibrium adsorption data were fitted to Freundlich and Temkin isotherms at 298K. Adsorption followed Intra – partical - diffusion rate kinetics.   Thermodynamic parameters ΔG*, ΔH*, ΔS* and Ea were computed, and showed that the adsorption process onto CKD was exothermic and non-spontaneous. Also adsorption studies suggest that physisorption might be the major mode of adsorption and CKD expressed as low affinity for removal of 1-(2¯- Hydroxy-4¯-nitrophenyl azo) -2-naphthol Dye onto the Cement Kiln Dust  that the high percentage removal was found ≈50%  at 298K , pH=6.Keywords: Cement Kiln Dust; Azo dyes; Adsorption isotherms; Kinetic study; Thermodynamic study.
The Employment of Standard Addition Method for the UV Spectrophotometric Assay of Diclofenac Alkaline Salts in Variant Pharmaceutical Dosage Forms Zaid Mahdi Jaber Al-Obaidi
Journal of Global Pharma Technology .
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Abstract

Objective: The standard addition method is widely utilised in the drug analysis protocols. The objective of this study is to perform a fast, easy, economy, and reliable method for the quantitation of diclofenac in different pharmaceutical dosage forms utilizing standard addition method with the employment of UV-Vis spectrophotometric technique. Methods: Four different dosage forms of diclofenac were selected to be analysed. These include: tablets, ampules, Emulgel, and powders for oral use. After preparing the samples with well-conducted procedures, the prepared samples were inoculated with predetermined spikes of the standards. Consequently, these prepared samples were analysed employing UV-Vis techniques. Results: As a result, the plotted standard curves for Cataflam, Voltaren Emulgel, Voltafast sachets, and Voltaren ampule showed good linearity with regression coefficients of 0.9984, 0.9988, 0.9981, 0.9992, and 0.9996 for respectively. The Limit of detection (LOD = 3SD) and Limit of quantification (LOQ = 10SD) were calculated for each dosage form. With the aid of the straight line equations, sample concentration was estimated for both techniques. The percent amount was found to be 99.04%, 105.5%, 98.64%, and 99.32% in respective order to the mentioned four diclofenac salts. Conclusion: The authors conclude that the standard addition method utilised in UV-Vis was as accurate, precise, fast, and economy, thus, can be used in routine laboratory drug-analyses.Keywords: Standard addition, Diclofenac sodium, Diclofenac potassium, Diclofenac diethylamine, Voltaren, Emulgel, Voltafast, Cataflam, UV-Vis, Diclofenac quantification.
Professional Self-Concept Model on Working Productivity of Clinical Nurses Kusnanto Kusnanto; I Gede Juanamasta; Slamet Riyadi Yuwono; Yulastri Arif; Kadek Ayu Erika; Hidayat Arifin
Journal of Global Pharma Technology Volume 12 Issue 09 (2020) Sept. 2020
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Abstract

Introduction: The nurses' professional self-concept is concerned with how individuals perceive themselves as professionals and in nursing is about what nurses feel about themselves as nurses. The purpose of this study is to develop a professional self-concept model on the productivity of the nurse's work. Methods: An explanatory design with cross-sectional approach. Samples were 311 nurses in inpatient room with simple random sampling. Data analysis using Partial Least. Organizational aspects (0.4397). Results: Characteristics of the work (0.1978) and the organizational environment (0.5391) were affects the nurses' professional self-concept. The self-concept of professional nurses affects work productivity (0.4953). Conclusion: Organizational characteristics, work characteristics, and organizational environment have a relationship with professional self-concept of nurses. Furthermore, the self-concept of professional nurses has a relationship and can enhance nurse work productivity. Professional self-concept nurses form a professional identity in nurses who increase nurse productivity at work.
Antibacterial Activity of Aquatic Zea Mays L. Hairs Extract against Different Bacteria in Babylon Province: An In-Vitro Study Rasha Hadi Saleh
Journal of Global Pharma Technology .
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Abstract

Background Zea Mays L. has been frequently used as a therapeutic agent used for treatment of various diseases .Objective A evaluation the antibacterial, anti-biofilm, adherence and swarming in hibitory activities of   Zea   Nujm mays L. hair extract against different bacteria. Methods: Well diffusion method, bio film inhibition test using a tissue culture plate, adherence and swarming inhibition assays were done for estimation and evaluation the anti-bacteriala activity of Zea mays L against a number of bacteria. Results: The result showed that Zea Mays L hair extracts the vying potent antibacterial activity. It’s also inhibiting adherence to epithelial cells and biofilm formations of the bacteria. The result shows that the extract has high anti-swarming activity .Conclusions: The extract has marked antibacterial activity. It can inhibit biofilm formation, swarming to ility, and bacterial cell adherence to oral epithelial cells. Keywords:  Biofilm, Bacterial adherence, Swarming.
Synthesis and Characterization of new Schiff base Derived from Benzothiazole with (Salicyldehyde and Saccharin) and Complexes for some Metal Ions (Co, Ni, Cd and Hg) Luay Ali Dhahi
Journal of Global Pharma Technology .
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Abstract

This research including preparation new derivatives for heterocyclic compounds are (1,3 benzothiazole), process synthesis in us research divided into two major pathways: First , synthesis 2- amino benzothiazole derivatives ethyl 2-aminobenzo[d]thiazole-6-carboxylate (HL).Second pathway ,reaction of salicyldehyde and saccharin with amine group of benzothiazole (HL) produced  of Schiff's base compounds(HL1,HL2). The compound was characterized by FT-IR, UV-Vis and 1H, 13C-NMR spectra. The complexes of the bivalent ions (M+2 =Co, Ni, Cd and Hg) with Schiff bases derived to give ligands (HL1, HL2) were prepared and then reacted with metal salts in ethanol as a solvent in (1:2) ratio (M: L). the complexes which have the general formula [M (HLn) 2Cl2] when (n=1, 2). Have been prepared and characterized by FT-IR, UV-Vis spectra, conductivity measurements, magnetic susceptibility. The proposed geometrical structures for all complexes were octahedral.Keywords: ligand, Benzothiazole, Salicyldehyde, Saccharin, Schiff bases, Complexes.
Investigation of Melanin in Dermatophytes that Isolated from Primary Schools Students Abbas Abdel Hussein Mohi
Journal of Global Pharma Technology Volume 11 Issue 05.
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Abstract

The study was conducted on four types of dermatophytes, including Trichophyton rubrub, T. mentagrophytes, Microsporium audouinii and M.canis. For isolated samples from primary school students under the age of sixteen, samples were collected from different areas of tinea capitis, tinea corporis and then identified the fungal infections to distinguish it from, other infections, such as eczema and traditional sensitivity, the diagnosis was done by direct examination of 10% KOH and then SDACC to observe the fungal structures where Morphological Description was identified. The fungus stimulated the production of melanin dye using a PDA medium for the four species. Melanin was detected in two ways copper silver sulfide (AgCuS) and light microscopy where the melanin was presented in the fungal structures of the hyphae and Conidial. The second method was grown for twenty-one days. Melanin was extracted and the melanin concentrations and carefully were observed using the scanning electron microscopy.Keywords: Melanin; Primary school; and Dermatophytes
Synthesis, Characterization, Antimicrobial Activity and Antioxidant of Azo Schiff Bases Containing Sulfanilamide Bushra K. AL-Salami
Journal of Global Pharma Technology .
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Abstract

Some new azo Schiff bases (SH1-SH6, SH14) were prepared in good yields by reaction of Sulfanilamide with 2, 4-dihydroxy-5-(phenyldiazyl) benzaldehyde and its substituted derivatives (Z1-Z6, Z14).  The structures of azo and azo-azomethine compounds were determined by FT-IR, 1HNMR spectroscopic techniques, EI-mass and elemental analysis.  The azo-azomethine compounds have been tested in vitro against Pseudomonas aeruginosa (-Ve) gram and Staphylococcus sciuri (+ Ve) gram in order to assess their antibacterial characteristic. Antioxidant efficiency of the azo-azomethine compounds examined.Keywords: Azo-azomethine, Azo compound, antioxidantand antibacterial activity, Sulfanilamide.
Information Processing in Accordance with the Rule of Cerebrovascular Mid-Term and Their Relationship to the Level of Performance of Some Scouting Skills for Studies Aqeel Yahya Hashim Abdulaziz
Journal of Global Pharma Technology .
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Abstract

The study of the mental and physiological aspects of the player and learner by the teachers and trainers today has become of great importance. The interest in the study of information processing and treatment levels has emerged as one of the types of learning that has to do with the individual learner himself and to guide him self-directed towards learning by drawing on his knowledge and there is a close connection and according to the type of mental sovereignty or the dominant style of thinking of the athlete whether he has cerebral dominance in the right half or left or there is integrated between the functions of the two halves, and recent years have seen a remarkable interest in the study And the importance of identifying the differences between the two halves of the brain, which contribute to the identification of many things related to human behavior and learning Scouting skills.The researchers followed the following steps in the research procedures:The descriptive approach was used in the method of interconnectivity.The study was conducted on the students of the first stage in the Department of Physical Education College of Education for Girls - University of Kufa for the academic year 2017-2018 The sample (33)The sample was divided according to the test of brain sovereignty to three groups represented the first group (right half), the second group represented (left half), and the third group represented (integrated system).The research requires the use of several tests, including the following:Information processing test.Test the level of information processing systems (right half, left half, integrated system).Skillful skill tests (nodular node, horizontal node).The results of the research:The level of information processing and accuracy of horizontal node performance of the right-hand system is better than those of the left and integrated system.The level of processing information undermining the tent for the right-wing system is better than those of the left and integrated system.Information processing is an important and essential role for people with right, left and integrated systems and the performance of horizontal node and node nodes.Keywords: Information processing, Cerebral dominance, Temporal node and horizontal node.
Role of-Added Sugar in Pediatric-Obesity Ayad Thabt Noaman
Journal of Global Pharma Technology Volume 11 Issue 6.
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Abstract

Added sugars, sweeteners of calories brought to the office or throughout processing and then training on foods, are the most important taxpayer for energy according to aged 2 years but older comes from added sugars. This level is higher than estimated due to 1976-1977 (12.1%), although it is significantly below the estimated 16.9% for 1998 after 2001, it exceeds encouraging guidelines. The biggest contributors to sugars brought in according to American diet are sugar-sweetened beverages, and adolescents are the biggest consumer. Since the devastation about added sugar linked to including weight problems as well as a lot of poor eating or physical repercussions, it is critical that pediatricians, after being aware of this amount, help this association and then after staying familiar with techniques that may Additionally use counseling for at risk patient and their family.
Improve Flour Quality by use Oxidized Agent during Tempering of Local Wheat Sakena Taha Hasan
Journal of Global Pharma Technology .
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Abstract

The Objective of this study was examined the effect of Oxidized Agent (hydrogen peroxide) added to temper water in order modify the quality of the local wheat flour. Chemical properties (protein, ash) and wet, dry gluten, gluten index and color. Rheological properties were measured by the farinograph, amylograph. Bread quality (Specific volume, Sensory evaluation). The hydrogen peroxide was added at three different levels (0, 0.01, 0.03%) to temper water wheat. Addition of hydrogen peroxide during tempering water wheat led to no significant increase in protein, ash, color and wet, dry gluten contained, but led to significant increase in gluten index. Addition hydrogen peroxide led to no significant increase on farinograph parameters. No significant effect on begin of gelatinization and viscosity temperature but there is significant positive effect on peak of viscosity curve. Significant positive effect on dough and bread quality, improved dough process Specific volume, crust color, symmetry of form, taste and chew ability. The optimal dose of hydrogen peroxide is (0.03%).Keywords: Hydrogen peroxide, Tempering, Local wheat, Dough rheology, Gluten, bread.

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