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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 1,093 Documents
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Direct Molecular Detection and Phylogenetic Relationship of Staphylococcus aurous from Mastitis Milk in Sheep and Cows Esraa T.M.
Journal of Global Pharma Technology Volume 11 Issue 05.
Publisher : Journal of Global Pharma Technology

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Abstract

The present study included the direct detection of Staphylococcus aurous isolated from milk of sheep and cows  infected by mastitis based 16SrRNA gene by PCR technique and study the phylogenetic relationship analysis based on spa gene of using DNA sequence method.  The study includes collected 32 sheep and 45 cow’s mastitis milk samples. These samples were submitted to milk DNA extraction, and then performed PCR technique. The PCR results were showed significant at P value: (< 0.05) in prevalence between sheep and cow Staphylococcus aurous positive isolates at (5/15.5%) and (14/31.1%) respectively.  DNA sequencing of partial sequence of spa gene was showed Staphylococcus aureus sheep isolate was genetic relationship analysis different than cow isolate and related to NCBI-Blast Staphylococcus aureus isolate H13939 (AM407304.1) at  (99%) homology sequence identity and NCBI-Blast Staphylococcus aureus strain AO124 (JX912490.1) at  (94%) homology sequence identity total genetic change (0.005). In conclusion, Staphylococcus aurous isolated from mastitis milk in sheep and cows were not related genetically. Therefore, Spa gene analysis was provides an efficient method for investigating phylogenetic relationships among different clinical isolates and can be useful for monitoring distribution of pathogen related to public health.Keywords: Staphylococcus aureus, Milk, Sheep, Cow, PCR, 16SrRNA, spa gene.
Synthesis, Spectral Characterization and Biological Activity of Dithiocarbamate-based Ligand and its Metal Complexes Mohamad J. Al-Jeboori
Journal of Global Pharma Technology .
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Abstract

This work is based on the synthesis, structural characterization and biological activity of somedithiocarbamate-based complexes. The free dithiocarbamate ligand was prepared via several synthetic routesincluding the formation of Schiff-base. The reaction of 2,6-diaminopyridine with benzaldehyde resulted in theformation of Schiff-base which reduced to the corresponding diamine by methanolic NaBH 4 . The reaction ofdiamine with CS 2 in a methanolic solution of KOH resulted in the preparation of the free dithiocarbamateligand. Macrocyclic complexes were formed from the reaction of the appropriate metal chloride with the ligandin an ethanolic medium. The suggested geometries around metal centres were determined using a range ofphysicochemical and spectroscopic techniques. The analytical and spectroscopic data revealed the formationof four and six coordinate complexes. Complexes of the general formula [M(L)] 2 (where M= Fe(II), Co(II) andZn(II) indicated metal centres adopt tetrahedral geometries. Complexes with the general formula [M(L)(H 2 O) 2 ] 2(where M= Mn(II), Ni(II), Cu(II) indicated octahedral structures around metal centres. Biological activity of theligand and its complexes against four strains of bacteria (Escherichia coli (E. coli), Pseudomonas aeruginosa,Bacillus cereus and Staphylococcus aureus) and antifungal activity against two types of pathogenic fungi,Aspergillus niger and Aspergillus parasiticus are tested.Keywords: Dithiocarbamate ligand; Transition metal complexes; Spectral characterization; Biological activity.
Various Technical Variables in Blanching, Coating, Frying to the Physicochemical Properties Fried Pigmented Potato (solanum tuberosum l.) Crisp Nguyen Phuoc Minh
Journal of Global Pharma Technology Volume 11 Issue 01.
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Abstract

Pigmented potato (Solanum tuberosum L.) varieties are a rich source of anthocyanins, in particular acylated derivatives. The potato products such as French fries, chips, balls etc. are also fried products which absorb high amount of oil. These products though taste good, pose health problems due to high calorie and cholesterol intake. The consumers prefer to low fat and fatfree fried foods. This research has been focused on different parameters of blanching, coating, frying, kind of frying oil for minimum oil absorption and sensory palatability while maintaining the most phytochemical components such as total phenolic, total flavonoid and anthocyanin during preservation. Results revealed that blanching 95oC in 30 seconds with ascorbic acid of 0.05 g/100g potato, coating with carrageenan 0.20%, frying 4 mm of potato crisp in sunflower oil heating at 155oC in 2 minutes was appropriated. Fried potato crisp could be preserved for 12 weeks at ambient 4oC. Moisture and oil content, as well as colour and texture are important quality attributes of fried potato products which were significantly affected by blanching.  Reducing the oil content of fried potato slices by application of coating is an effective method. Frying of potato crisps is carried out to convert the tubers to value added products. Frying method brings out unique flavor and texture to the products that improve their overall acceptability. Kind of oil used for frying also positively affected to oxidative reaction in fried potato crisps. The present study has examined various technical aspects to minimize the oil uptake in fried foods still retaining the desirable texture and flavor of the final product.Keywords: Potato crisp, Blanching, Coating, Frying, Shelf life, Anthocyanin, Flavonoid, Carrageenan.
Copper Tetra-Tert-Butyl Phthalocyanine Thin Films for Ammonia Gas Detection Ameer A. Alhusseiny
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Abstract

Thin films of copper tetra-tert- butyl Phthalocyanine (CuPc) have been prepared from their solution in chloroform using spin coating technique. Films then heated to (100, 200 and 300) oC to study the effect of annealing temperature on the characteristics of the prepared films. UV-visible spectrophotometer was used to investigate the absorption properties of the materials as well as the optical energy gaps. The morphology characteristics have been carried out utilizing atomic force microscopy (AFM). To demonstrate the sensing properties of CuPc films, I-V measurements were carried out using Keithly 2400 instrument to calculate the resistance before and after exposure to ammonia odorant. The prepared samples show a decrease in the resistance values after exposure to the contaminated air. Time dependency was also carried out to investigate the response and recovery time of the prepared device.Keywords: Copper phthalocyanine, Thin films, Gas sensor, Ammonia detection.
The Effect of Using Pain Management Techniques in the Rehabilitation of Chronic Lower Back Injury in Athletes and Non-Athletes Haider Jumaah Asree Ktaiman
Journal of Global Pharma Technology .
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Abstract

In the past few days increased chronic lower back pain, where today is a disease of the era due to the high effort and continuous and disproportionate exercise of the athlete and loads of low back, and the fact that chronic lower back pain is a disease of the modern era and through the experience and work of researchers in medicine Physical therapy and physiotherapy have found that there is little or no use of pain management techniques to treat chronic low back pain and that chronic low back pain is a disease of the modern age. Therefore, researchers considered this study as the first study in Iraq in terms of Techniques in pain management to treat chronic lower back pain. The researchers used the experimental method was the sample included the 12 players injured who suffer from the bottom of the chronic back pain represented by convulsions and muscle cramps, chronic where formed the experimental group of 6 players used pain management techniques within the program consists of 16 weeks either the control group used its traditional 16 week. Search Results showed superiority of the experimental group on the control group in the test Schober to measure the degree of pain where he showed differences (0.021 (in the test side flexibility differences emerged (0.01).Keyword: Pain management techniques, Rehabilitation, Lower back injury.
Effects Cuminum cyminum Extracts in Lipid Profile Levels and Internal Tissues of Infected Balb/c Mice with Hydatid Cysts Maroof Sabti Juma Al-Ammash
Journal of Global Pharma Technology .
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Abstract

Hydatidosis is one of the most cosmopolitan zoonotic disease that may causes death and still very common in the developing world. The present study aimed to detect the effects of Albendazole and C. cyminum extracts on lipid profile, liver and spleen of infected Balb/c mice with hydatidosis. This study showed positive results for tannins, phenolic compounds, flavonoids and glycosides in alcoholic and aqueous extracts of C. cyminum, while negative result for  alkaloids. Significant (p ≤ 0.05) increasing of total cholesterol was detected for the third (273.57 mg/dl) and fourth (281.73 mg/dl) positive control groups.   Triglycerides shows significant increasing in groups 3 (248.65 mg/dl) and 4 (260.30 mg/dl) of positive control groups. About HDL-C, significant decreasing was recorded  in the third and fourth positive control groups (40.87 mg/dl and 33.42 mg/dl, respectively), while significant (p ≤ 0.05) elevation  was occurred for HDL-C in Albendazole treatment group (60.87 mg/dl) as compared with the negative control group, with no significant differences were reported for HDL-C in alcohol and aqueous extract treated groups. For histological study, the present study showed degeneration of hepatocytes, thickening wall of hepatic blood vessels and infiltration of lymphocytes for Albendazole treatment group, while alcoholic and aqueous extract treated groups showed central vein, hepatocytes and sinusoids with normal sizes. Concerning spleen, results in the current study showed normal shape and size for white pulp, red pulp and central artery of all treatment groups, while edema and necrotic materials appeared in some of positive control groups.Keywords: Hydatidosis, Hydatid cyst, Cuminum cyminum extract Histological effects.
Predictors of Quality of Life in Patients with Heart Failure: A Literature Review Ah. Yusuf
Journal of Global Pharma Technology Volume 12 Issue 09 (2020) Sept. 2020
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Abstract

Heart failure (HF) is a chronic disease characterized by reduce heart efficiency affecting patients’ quality of life (QoL). Patients with HF report lower QoL compared with general population and other patients with chronic disease. There are multidimensional factors affecting QoL. Therefore, it is important to identify factors that could be associated with changes in QoL to improve outcomes. The aim of this study was to identify significantly factors related to QoL in patients with HF according to the available literatures. The literatures were searched in appropriate database, using PICO framework, from January 2012 until August 2018. Eighteen relevant articles were found and reviewed. Factors that are significantly related to QoL in patient with HF can be grouped into 5 categories, i.e. physical factors include physical symptoms, physical activity, functional status, duration of HF, and multiple hospitalization; psychosocial factors include depression, optimism, exercise self-efficacy, and living independently; behavioral factors include self-care engagement, water and sodium restriction; spiritual factors include acceptance of illness and existensial well-being; and demographic characteristics include age, sex, education, economic and employment status. This review provides insight on potentially factors affecting QoL. Proper intervention in modifying those factors is expected to improve the quality of life. Keywords: Heart failure, Quality of life, Health-related quality of life, Predictors.
The Relationship between Employees’ Work Commitment and Organizational Policies (Housing and Urban Development Office of Chaharmahal and Bakhtiari Province) Meisam Jamalzadeh
Journal of Global Pharma Technology Vol. 9 Issue 7 : 2017
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Abstract

Today, organizations' attention to maximize the capabilities of their employees has substantially grown. However, it should be noted that employees do not necessarily apply all their capabilities to accomplish the objectives of the organization. One of the most important reasons for this is the lack or shortage of organizational commitment of the staff. Accordingly, this study strived to investigate the relationship between employees’ commitment and organizational policies in the Housing and Urban Development Office of Chaharmahal and Bakhtiari province. The research method is applied in terms of the type of research and is a survey method in terms of data collection method. To achieve the research objectives, among from 456 employees of the Housing and Urban Development Office of Chaharmahal and Bakhtiari province, 243 individuals were selected as the study sample. Using a researcher-made questionnaire, employees' commitment and organizational policies were assessed. In order to test the research hypothesis, LISREL software and the structural equation modeling analysis method were used. The results of the study indicated the relationship between different components of organizational policies such as role clarity and role conflict with organizational commitment of the employees.Keywords: Employees’ Organizational Commitment, Organizational Policies, Housing and Urban Development.
Efficacy of Dialectical behaviour Techniques (DBT) in Reduction of Anxiety of Students in Tehran- Iran Shahrbanoo Ghahari
Journal of Global Pharma Technology .
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Abstract

Background and objective: Dialectical Behavior Therapy techniques can be used as useful and effective method in reduction of many clinical symptoms. In this study, Efficacy of dialectical behavior therapy in reduction of   anxiety of students in Tehran City is investigated. Methods and materials: this study is in kind of empirical study with pretest and posttest design with control group. Statistical population in this study consists of all high school female students of Tehran (n=674) educating during academic year of 2015-2016. First, cluster sampling is used and 4 schools are selected from schools of Tehran and from each couple of schools, 2 classrooms were selected and the students with high score in Beck's Anxiety Inventory (BAI) were selected as sample. Then, 30 students were selected using random sampling method and were placed in two groups with 15 people in each group. Both groups fulfilled the BAI in basic step. Experimental group received 12 sessions’ intervention with dialectical behavior therapy techniques and control group remained in waiting list. Both groups fulfilled BAI again after the treatment. Obtained data are analyzed using MANCOVA. Results: obtained results from the study showed that Dialectical Behavior Therapy can affect reduction of anxiety of female students and mean values of both groups are significantly different from each other (p<0.01).Conclusion: Dialectical Behavior Therapy (DBT) techniques can lead to reduction of anxiety of female students.Keywords: Dialectical behavior therapy (DBT) techniques, Anxiety, Female students.
Implementation Development Of Work Climate To Better Worker Productivity Employee In Stikes Hang Tuah Surabaya Dedi Irawandi
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Productive nurses are produced from qualified educational institutions. To achieve optimal work productivity growth required several supporting factors, one of them is the harmonious working climate.  This work purports to obtain a photo of the workplace climate and its relationship to employee productivity. The dimensions of the employment climate in search are (1) the concept of the psychological dimension of employees; (2) the structural proportions of employees; (3) social dimensions of employees; (4) employee bureaucratic dimension.  This research uses a quantitative and qualitative approach. The Result of research (1) Worker productivity at Stikes Hang Tuah Surabaya shows good work productivity (58%), unfavorable (42%), (2) Psychological dimension related to work productivity; (3) Structural dimension is not related to work productivity; (4) Social dimension related to work productivity; (5) The bureaucratic dimension is not related to work productivity. Recommendations for the management, need to be developed further standard performance of a team sharing development and application of a fair reward system for the achievers and penalties for the violators

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