cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
I Wayan Sudarsa
Contact Email
sudarsa@unud.ac.id
Phone
-
Journal Mail Official
globalpharmatechnology@gmail.com
Editorial Address
India
Location
Kota denpasar,
Bali
INDONESIA
Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 1,093 Documents
 58   59   60   61   62 
Search results for , issue "." : 1,093 Documents clear
Pharmacokinetic Modification of Colon Targeted Delivery systems of Tegaserod Maleate based on Osmotic Technology R. Margret Chandira
Journal of Global Pharma Technology Volume 10 Issue 12.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Colon targeted delivery systems of Tegaserod maleate based on osmotic technology were developed. The developed systems consisted of osmotic core (drug, osmotic agent and wicking agent), coated with semipermeable membrane (spm) containing guar gum as pore former, coated core were then further coated with enteric coating to protect the system from acidic environment of stomach. the effect of various formulation variables namely the level of wicking agent (sodium lauryl sulphate), osmotic agent in the osmotic core, the level of pore former (guar gum) in spm, were studied on physical parameters and drug release characteristics of developed formulations. Tegaserod maleate release of drug is directly related to the level of pore former, wicking agent and osmotic agent. The drug release from the developed formulations was independent of pH.  The thickness of enteric coating could prevent formation of delivery pores before contact with simulated colonic fluid, but had no effect on drug release. Result of spm studies showed the formation of in-situ delivery pores in the membrane from where the drug release occurred, and the number of pores formed were directly related to the initial level of pore former (guar gum) in spm. the manufacturing procedure was found to be reproducible and formulations were found to be stable during 3 months of accelerated stability studies.
Some Biochemical Parameters in Congestive Heart Failure Patients in Baghdad City Suha A. Al-Jowari
Journal of Global Pharma Technology Volume 11 Issue 05.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The present study was designed to study the changes on some biochemical parameters in males with congestive heart failure (CHF). Ninety males with age ranges from (27-73) years have been involved in this study, divided into two groups; the first group involved 65 males with CHF and the second group involved 25 males without CHF from Teaching Baghdad Hospital. The patient's groups were divided according to their age into three groups (less than 40, 40-50 and more than 50 years). Blood samples were collected from each patient and control and used for analysis of renal function parameters, potassium, calcium and liver function. The results of the current study showed a highly significant (p < 0.01) increase in the concentration of blood urea, serum creatinine in HF patients as compared with the control group. While there is non-significant difference in the level of potassium in HF patients compared with the control group. Further, there was a highly significant (p < 0.01) decrease in concentration of calcium in patients group compare with the control. This study also illustrates a highly significant (p<0.01) increase in the liver function parameters which include alanine aminotransferase (ALT) and aspartate aminotransferases (AST) of HF patients compared with the control group. While there is non-significant difference in alkaline phosphatases (ALP) of HF patients compared with control group. There was also significant (P< 0.05) increase in total serum bilirubin (TSB) concentration of HF patients compared with the control group.Keywords: Congestive heart failure, Urea, Creatinine, ALT, AST, ALP, TSB.
The Effect of Cirprofloxacin (CPX) on the Histological Structure of Albino Rabbit Ovary Jabbar Ebadi Mohammad
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The study was conducted in the Animal House of the Department of Biology / Faculty of Education for Women / University of Kufa from October 2016 to May 2017. The study included 72 lab albino rabbit eggs of the type Oryetolagus cuniculus.L divided into four groups of 18 rabbits. They were injected with ciprofloxacin at a concentration of 1 mg / kg bw. The bacteria dose was (1 mg / kg bw) for a week, two weeks, and four weeks respectively. After infusion and injections of all experiment animals, they were sacrificed and dissected for the histological study, which included the female reproductive system. As well, blood samples were taken for blood and chemical indices. The results of the statistical analysis at the probability level (P <0.05) showed that the antibiotic (ciprofloxacin) caused changes in weight by significant decrease (P <0.05) in the total body weight and ovarian weight in females. The results of the statistical analysis of the study showed that the single therapeutic injection of ciprofloxacin and bacterial injection were different in their effect on some blood parameters. The groups of drug and bacterial treatment did not show changes in the first and second weeks, while there was a significant decrease and below the probability level (P <0.05) in the fourth group by number of WBCs, RBCs and hemoglobin (Hb) compared to the control group. Under optical microscopy, the histological study of tissue sections showed patho-histological changes of different intensity and appearance in the female ovaries between the drug and bacteria compared to the control group. The results of the microscopic examination showed clear effects on ovarian tissue structure in females compared with control group.Keywords: Ciprofloxacin; Biochemical tests; Biology; Histopathology; Ovary ; Albino female rabbits.
A Study of Adsorption of Malachite Green from Aqueous Solution on Graphene Oxide/Polyvinyl Pyrrolidone/Acrylic Acid Layth S. Jasim Al-Hayder
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Graphene oxide/polyvinyl pyrrolidone/acrylic acid (GO / PVP / AAc) was prepared. It is a composite hydro gel. They were synthesized by the self-assembly of polyphinylpyrolydone (PVP), acrylic acid (AAc), and Graphene oxide (GO). This composite hydro gel , GO- based , were used to remove two types of dyes , Malachite Green (MG) of its aqueous solutions. It was found that the composite hydrogel prepared have a high surface area. Various experimental variables were studied, such as, contact time (1-180 min), adsorbent surface mass (0.01-0.1 g), the initial concentration of the absorbat material (10-1000mg / L) for both two types of dyes. Also studied were the effect of each temperature, ionic strength, and pH. The experimental isotherm data were also analyzed using the linear forms of Langmuir, Freundlich, and Temkin equations, in order to determine the maximum adsorption capacity. Thermodynamic functions of Adsorption process were also studied, Gibbs free-energy (DG), Entropy (ΔS), and Enthalpy (∆H).Keywords: Adsorption, Composite, Malachite Green, Isotherms, Thermodynamic.
The Relationship of Mental Fatigue (Flim) With the Level of Hormone Cortisone and the Performance of Running (100) Meters for Young Players Hayder Naji Habash Alshawi
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Mental fatigue works to produce cortisone, which causes a series of reactions in the body, including weakness of the immune system and tension in the large muscles ,high blood pressure, and the recurrence of the high rate of cortisone, which leads to the death of brain cellsespecially in the area which is called the hippocampus, an area necessary for memory .(1)The events of the track and the field require special requirements of physical specifications and physical abilities in addition to the training methods for each of the effectiveness of the success and from these events that require a high level of the effectiveness of running 100 meters .(2)The problem of research was that the work of hormones in the body of the important topics in the field of sports physiological psychology in general and in the track and field activities, especially the activity of 100 meters .(3)The problem of looking for the work of hormones in the body of important topics in the field of sports physiological psychology in general and in the arena and field activities, especially the effectiveness of 100 meters ,As the interest of researchers focused on the development of physical abilities, planning and skill and lack of attention to the psychological aspect, which greatly affects the achievement, despite its importance, which is considered the dominant side of the rest of the capacity and mental fatigue of the nervous system and its relationship to achievement and its effects on the secretion of cortisol is considered these variables that affect The players of the effectiveness of the 100 m and therefore affect the results of achievement because the fatigue that gets to the players during fatigue will reduce the activity of the nervous system and therefore cannot show the player all his abilities and do not reach the desired achievement and poor performance So wanted researchers conducting this study, an attempt to achieve the best results using a test of the tests Vienna system (mental fatigue FLIM) and its relationship to the level of the hormone cortisol, and the aim of the research to identify the relationship between mental fatigue and the level of the hormone cortisone and the performance in the 100 meters running for young player. The researchers used the descriptive approach in the method of interrelationships to suit the nature of the problem on the players of the 100 meters advanced to the clubs of Iraq and were selected in a comprehensive inventory, tests used in research, test (mental fatigue) .The researchers concluded that there was a significant correlation between mental fatigue (frequency of fusion) (VF) and cortisone concentration as well as performance ,in addition, there is a significant correlation between mental fatigue (frequency of flashes) (FF) and the level of hormone cortisone and performance . The researchers recommend that the coach to pay attention to knowledge of the values of mental fatigue to the players in addition to knowing the levels of hormones in order to be able to address the problems facing players and how to overcome them ,as the high rate of cortisone evidence of tension in the player and the duty of the coach to address the excitement and tension of the players being a negative impact on their performance .Keyword: Mental fatigue, Hormone cortisone, Performance and running
The Effect of Interpersonal Communication, Emotional Intelligence, Supervision and Motivation of Achievement in Caring Behavior in Nursing Abdurrahman Abdurrahman
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: The application of caring behavior based on knowledge of attitudes and professional behavior is important in nursing services. Nursing students who are carrying out professional education in hospitals must be able to understand and apply caring behavior in providing nursing care to patients. This study analyzes the effects of interpersonal communication, emotional intelligence, supervision, and achievement motivation on the caring behavior of nurses students in applying nursing care. Methods: Quantitative research with a path analysis approach. Sampling used a simple random sampling technique as many as 271 respondents from 871 populations. Data were collected using a developmental questionnaire. Results: interpersonal communication (p=0.385), emotional intelligence (p=0.134), clinical supervision  (p=0.286), achievement motivation (p=0.119) had a positive effect on caring behavior. Conclusion: Increasing interpersonal communication, emotional intelligence, clinical supervision, and achievement motivation can improve caring behavior.Keywords: Achievement motivation, Caring behavior, Emotional intelligence, Interpersonal communication, Supervision.
Health Risk Assessment of Some Heavy Metals Pollution in Muscles of Barbus xanthopterus (Heckel, 1843) in Al-Gharraf River Southern of Iraq Wisam Th. Al-Mayah
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

One sampling station was selected to conduct the study in Al-Gharraf River in Kut -Al-Haay city. The samples were taken from the study station at once every month from June of 2017 until May 2018 for year. The study results showed that the mean concentrations heavy metals are vary seasonally in their levels and analyses of muscles indicate that Ni occupied the first position and revealed the highest levels, in general. The minimal recorded accumulative value (0.187ppm) was in spring and the highest (0.251 ppm) in summer. Zinc occupied second accumulation levels and showed the minimal (0.039 ppm) in spring, whereas Cd, by no means, exhibited the minimal concentrations and the lowest value (0.0053 ppm) was in winter.Keywords: Heavy Metals, Fish, Water Pollution, Al-Gharraf River. 
Anti-Dandruff Activities of Ethanol Extract and Water, N-Hexan, Ethyl Acetate Fractions of Key Lime (Citrus Aurantifolia) Leaves Against Malassezia Furfur Resmi Mustarichie
Journal of Global Pharma Technology Volume 12 Issue 09 (2020) Sept. 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The objective of this research was to determine the Anti-dandruff characteristic of ethanol extract and its fractions of key-lime leaves (Citrus aurantifolia L) against the fungus Malassezia furfur. C. Aurifolia leaves were collected from villagers' vegetable crops in Kendari, Southeast Sulawesi, Eastern Indonesia. It was macerated with ethanol 96%, rotary evaporated till viscous extract was obtained. The extract was analyzed its phytochemical substances and tested its Minimum Inhibitory Concentration (MIC). The extract was fractionated using ethyl acetate and n-hexane. Both ethanol extract and its fractions were tested their anti-dandruff activity using the fungus Malassezia furfur. DMSO was used as negative control and ketoconazole 1% as a positive control. All data were statistically analyzed. Phytochemical screening found that key-lime leaves contained flavonoids, polyphenols, saponins, steroids & triterpenoids, and tannin. The results showed that key-lime leaf extract was able to inhibit the activity of the Malassezia furfur fungus, the inhibition zones of the extract were 1% (6.0 mm), 4% (7.55mm), 8% (8.44 mm), 16% (9.9 mm), and 29% (16.7) mm) which was slightly greater than 1% ketoconazole as a positive control. The higher the concentration of lime leaf extract, the greater the inhibitory power against the Malassezia furfur fungus. Statistical data shows that the fraction of key-lime leaf had the best antifungal effect shown by the ethyl acetate fraction. The study concluded that either ethanol extract or its fractions of c.aurantifolia leaves has anti-dandruff activity against M. furfur. The ethyl acetate fraction was found to have a better activity compared to n-hexane and water fractions. This finding could be useful to elucidate the compound which is responsible for this action. Keywords: Citrus aurantifolia, Anti-dandruff, MIC, Malassezia furfur, Ethanol extract.
Measuring the Sedimentation Rate of Red Blood Cells in Infected Camels with Respiratory Disease like Pneumonia, Bronchitis and inflammation of Lung Zahra M Al-Hakak
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The objective of this study is to determine sedimentation rate of red blood cells in Iraqi camels   and compare the value between diseased and healthy animals. A total of 150 samples of blood were collected from Iraqi camels. All samples were collected randomly from both sexes and from different ages ranged from (less than a year-15 years) .Some camels were suffering from different diseases and injuries. The study included: 1. General knowledge examination: (age of the animal - type of animal - color - history of the condition - drugs and vaccines used and the method of grazing). 2. Clinical examination included: (check the temperature - the speed of the pulse and breathing - auscultation of the heart by stethoscope - check covering of skin). 3. Measure the sedimentation rate of red blood cells (ESR) through three hours. Results showed a clinical examination that there are (45) animal was suffering from various diseases and (105) animal healthy. The results of the examination (ESR) values ranged in healthy animals in the first hour (0.33-1.6) mm / h ,in the second hour (1.56 -2.3) mm / h and in the third hour (2.66-3.44) mm / h While in sick camels the results of the examination (ESR) values ranged in the first hour (1.75-5) mm / h ,in the second hour (5 -13.5) mm / h and the third hour (7.75-19.5) mm / h .The test results showed that (ESR) higher in animals that were suffering from the disease showed a statistical significant level of difference (0.05> P) between healthy and diseased camels .Recommendations The study recommended that must be done with many other studies on the blood of camels to the lack of such a research in Arab library, deepen the field studies on camels and must be supported by the state and specialists.Keywords: Red blood cells, Sedimentation Rate, Pneumonia, Bronchitis, Camels, Iraq.
Evaluation of Analgesic Activity of Extracts of Jasminum sessiliflorum Ruby Philip
Journal of Global Pharma Technology Volume 12 Issue 01 (2020) Jan. 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The present study was designed to investigate analgesic activity of ethyl acetate and ethanolic extracts of Jasminum sessiliflorum. The analgesic activity was assessed by using acetic acid induced writhing method and tail immersion tests in rats. The ethyl acetate and ethanolic extracts decreased the acetic acid induced abdominal contractions and also significantly increased the reaction time of tail immersion test [1]. These results showed that the plant extracts had both central and peripheral analgesic action. The  results  suggest  that the extracts  of J.sessiliflorum possesses potent analgesic properties, which support its use in traditional medicine and suggesting that the plant should be further investigated for its pharmacological active natural products [2]

Page 60 of 110 | Total Record : 1093

 58   59   60   61   62 

Filter by Year

2010 2026


Reset
Filter By Issues
All Issue Volume 18 Issue 01 (2026) Jan. 2026 Volume 17 Issue 12 (2025) Dec. 2025 Volume 17 Issue 11 (2025) Nov.2025 Volume 17 Issue 10 (2025) Oct. 2025 Volume 17 Issue 04 (2025) April 2025 Volume 17 Issue 03 (2025) March 2025 Volume 17 Issue 02 (2025) Feb. 2025 Volume 17 Issue 01 (2025) Jan 2025 Volume 16 Issue 12 (2024) Dec. 2024 Volume 16 Issue 11 (2024) November 2024 Volume 16 Issue 10 (2024) October 2024 Volume 16 Issue 09 (2024) September 2024 Volume 16 Issue 08 (2024) August 2024 Volume 16 Issue 07 (2024) July 2024 Volume 16 Issue 06 (2024) June 2024 Volume 16 Issue 05 (2024) May 2024 Volume 16 Issue 04 (2024) April 2024 Volume 16 Issue 03 (2024) March 2024 Volume 16 Issue 02 (2024) February 2024 Volume 16 Issue 01 (2024) January 2024 Volume 14 Issue 05 (2022) May 2022 Volume 13 Issue 05 (2021) May 2021 Volume 13 Issue 04 (2021) April 2021 Volume 13 Issue 03 (2021) March 2021 Volume 13 Issue 02 (2021) Feb. 2021 Volume 13 Issue 01 (2021) Jan. 2021 Volume 12 Issue 12 (2020) Dec. 2020 Volume 12 Issue 11 (2020) Nov. 2020 Volume 12 Issue 10 (2020) Oct. 2020 Volume 12 Issue 09 (2020) Sept. 2020 Volume 12 Issue 08 (2020) Aug. 2020 Volume 12 Issue 07 (2020) July 2020 Volume 12 Issue 06 (2020) June 2020 Volume 12 Issue 05 (2020) May 2020 Volume 12 Issue 04 (2020) April 2020 Volume 12 Issue 03 (2020) March 2020 Volume 12 Issue 02 (2020) Feb. 2020 Volume 12 Issue 01 (2020) Jan. 2020 Volume 12 Issue 08 Volume 11 Issue 12 (2019) December 2019 Volume 11 Issue 11 (2019) November 2019 Volume 11 Issue 10 (2019) October 2019 Volume 11 Issue 09 (2019) September 2019 Volume 11 Issue 09: (2019) September 2019 Volume 11 Issue 08 (2019) Aug. 2019 Volume 11 Issue 07 (2019) July 2019 Volume 11 Issue 06 (2019) June 2019 Volume 11 Issue 05 (2019) May 2019 Volume 11 Issue 04 (2019) April 2019 Volume 11 Issue 03 (2019) March. 2019 Volume 11 Issue 02 (2019) Feb. 2019 Volume 11 Issue 01 (2019) Jan. 2019 Volume 11 Issue 2: 2019 Volume 10 Issue 12. Volume 11 Issue 6. Volume 10 Issue 12 (2018) December 2018 Volume 10 Issue 11 (2018) November 2018 Volume 10 Issue 10 (2018) October 2018 Volume 10 Issue 09: (2018) September 2018 Volume 10 Issue 08: (2018) August 2018 Volume 10 Issue 07: (2018) July 2018 Volume 10 Issue 06: (2018) June 2018 Volume 10 Issue 05: (2018) May2018 Volume 10 Issue 04: (2018) April 2018 Volume 10 Issue 02: (2018) Feb 2018 Volume 10 Issue 01: (2018) Jan. 2018 Volume 10 Issue 10: 2018 Volume 10 Issue 01 Volume 09 Issue 12 Volume 09 Issue 11 Volume 9 Issue 11 . Vol. 9 Issue 7 : 2017 Volume 9 Issue 10 Volume 09 Issue 09 Volume 09 Issue 08 Volume 9 Issue 07 Volume 09 Issue 05 Volume 09 Issue 04 Volume 09 Issue 03 Volume 09 Issue 02 Volume 08 Issue 11 Volume 08 Issue 07 Volume 08 Issue 06 Volume 08 Issue 05 Volume 08 Issue 04 Volume 08 Issue 03 Volume 08 Issue 02 Volume 08 Issue 01 Volume. 9 Issue 6 Volume 08 Issue 10: (2016) October 2016 Volume 08 Issue 09: (2016) September 2016 Volume 12 Issue 01 Volume 11 Issue 07 Volume 11 Issue 05. Volume 11 Issue 04. Volume 11 Issue 03 Volume 11 Issue 01. Volume 08 Issue 08 Volume 04 Issue 02: (2012) February 2012 Volume 03 Issue 06: (2011) June 2011 Volume 03 Issue 04: (2011) April 2011 Volume 02 Issue 10: (2010) Oct.2010 Volume 02 Issue 07: (2010) July 2010 Volume 02 Issue 05: (2010) May 2010 Volume 02 Issue 03: (2010) March 2010 More Issue