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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 1,092 Documents
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Evaluation the Fractions from Extract Ethanol Psidium Guajava Leaves on Total Phenolic Content, Antioxidant Activity and Its Antibacterial Activity of Staphylococcus Aureus. Mustofa Ahda
Journal of Global Pharma Technology Volume 11 Issue 01.
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Abstract

Objective: The aims of this research to find the potential extract and fraction from ethanol extract of Psidium Guajava L for natural antioxidant and antibacterial. The extract and fraction of Psidium Guajava L was analyzed the phenol total content, antioxidant activity and its antibacterial. Methods: The ethanol extract of Psidium Guajava L was extraxted using n hexane, ethyl acetate and water. The all fraction and ethanol extract of Psidium Guajava L was determined the scavenging activity, penolic compound. The scavenging activity was determined by DPPH method. The phenolic compound was determined with Folin-Ciocalteu method. Results: The result of this research showed that the fraction of ethyl acetate has highest antioxidant activity with the value is 9.07 µg/mL. It is also supported by the result of screening phytochemical that ethyl acetate fraction contains mostly complete of chemical substances. However, The highest total phenol content was found in water fraction with phenolic content of 26%. The anbacterial activity of ethanol 96% extract of Psidium guajava leaves and ethyl acetate fraction have a highly activity to inhibit the Staphylococcus Aureus. Conclusion: The fraction of ethyl acetate has a highest of antioxidant activity, although it doesn’t have highest of total phenolic content. The highest of total fenolic content from water fraction is 26%. The scheme of antibacterial activities potential of Guajava extracts are ethanol 96% extract = ethyl acetate fraction > n-hexane fraction = water fraction
Furnace Redesign to Reduce Levels of Dust in the Air, Fatigue, Workload, and Increasing Blacksmith Productivity in Batu Sangiang Village, Tabanan, Bali-Indonesia Ida Ayu Made Sri Arjani
Journal of Global Pharma Technology Volume 11 Issue 08 (2019) Aug. 2019
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Introduction: Exposed to a hot environment for work is a situation that can potentially pose a danger to the safety and health of workers. Besides resulting in pain and injury, it can also cause occupational diseases. Blacksmithing was carried out with furnace and open flame, where the iron that will be heated with a sharp object repeatedly were sharpened again. The working process is quite heavy with exposure to heat radiation from the furnace and dust increasing fatigue and workload of a blacksmith. Therefore, to avoid the occurrence of health problems caused by exposure to high heat furnaces, a need for an ergonomic and good chimney that can provide comfort for its workforce. The purpose of this research is to reduce levels of dust in the air, fatigue, workload, and increasing blacksmith productivity in Batu Sangiang Village, Tabanan with furnace redesign. Methods this is an experimental research study. This research was conducted in the Batu Sangiang Village, Tabanan with a sample of 15 workers. Data collected include: levels of dust in the air, fatigue, workload, and work productivity. Before setting up a different test, the data normality was tested using Shapiro-Wilk test with a confidence level α = 0.05. In normal distributed data, Paired Sample t-test with α = 0.05 was used and abnormal distributed data were analysed using the Wilcoxon different test, α = 0.05, Results After working furnace was redesigned, decreased levels of dust in the air 89.20%, 24.03% reduction in fatigue, reduced workload of 14.48% and 83.26% increase in productivity. Results analysis using Paired Sample t-test, the amount of dust in the air, fatigue and workload in Period I and Period II, there is a significant difference (p <0.05), as well as analysis data using Wilcoxon test, labor productivity in Period I and period II, there is a significant difference (p <0.05). Conclusion: From this study we can conclude, after the furnace redesign was done, there was a significant decrease in the levels of dust in the air, fatigue and workload, and there was a significant increase in labour productivity. Suggested artisan blacksmith always applies and pay attention to the principle of ergonomics for improvements such as the redesign of the furnace shown to reduce levels of dust in the air, fatigue, and the workload and increase productivity.Keywords: Furnaces redesign, Levels of dust in the air, Fatigue, Workload and work productivity.
The Effects of Methane Storage Capacity Using Telmisartan Organotin (IV) Complex Emad Yousif
Journal of Global Pharma Technology Volume 11 Issue 04.
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Abstract

The fabrication of porous dibutylorganotin (IV) complex as methane storage was successful. Interesting physiochemical properties for diorganotin (IV) complex were observed using a combination of several techniques such as scanning electron microscopy, Brunauer–Emmett–Teller and nitrogen adsorption–desorption isotherm, Barrett–Joyner–Halenda and H-sorb 2600 analyzer. The mesoporous complex exhibit tunable porosity with Brunauer–Emmett–Teller surface area (SABET = 130.357 m2.g-1), pore volume (0.162 cm3.g–1) and narrow pore size distribution; the complex was found to has high physico-chemical stability. At 323 K and 50 bars, the complex has methane uptake (up to 1.116 cm3·g–1). The field emission scanning electron microscopy images, at different 100 and 50 µm magnification powers were confirmed, the morphological images of the polymeric film showed a rough surface.  Keywords: Gas storage; Methane capture; Diorganotin (IV) complex; Field emission scanning electronic microscope.
Epidemiological Characteristics of Acute Leukemia in Child Welfare Hospital in Baghdad Samahir A. Fadel
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Background: Acute leukemia, the most common form of cancer in children, comprises approximately 30% of all children malignancies, with acute lymphocytic leukemia (ALL) being more common than Acute Myeloid Leukemia (AML) by five times. Objectives: To determine different epidemiological variables associated with acute leukemia& to determine the patterns according to socio demographic data. Patients and Methods: A cross- sectional study and the data collection was carried out for a period of four months, from the 2nd /May/2019 to 2nd /September /2019. Result: The study shows that the majority of patients were ALL & the highest percentage of ALL patients was in the age group (5-9) years, males showed higher percentage than females in both type of leukemia, the highest percentage were from Urban.The majority of patient’s parents’ education level was primary; while the highest percentage of fathers’ occupation was Private sectors & the highest percentage of mothers’ occupation were Housewife.The highest percentage of ALL patients were 4th & more Order in family& AML were the 1st child, the highest percentage of patients with Birth space (2-4) years from there brothers.The highest percentage of patients was feed from their mothers (Breast feeding) during their first year & the highest percentage of patients was normal birth weight.Majority of patient’s Parent consanguinity were not related, while the lowest percentage of patient’s Parent consanguinity were far related.There was an important association between  patients’ blood group AB & ALL. Conclusions: The study shows that the majority of patients were ALL & the highest percentage of ALL patients was in the age group (5-9) years, males showed higher percentage than females in both type of leukemia, the highest percentage were from Urban. Recommendations: Ensure good MCH system to monitor and ensure the quality of health care practice & demonstrating cultural competency to promoting more effective child health services.Keywords: Leukemia, Blood, Cancer, Childhood, Iraq.
The Prevalence of Infection with Scabies, Yellow Fever and Myiasis in Some Ruminants in Thi-Qar Governorate During 2017 Sadek J.T.
Journal of Global Pharma Technology .
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Abstract

The infection of external parasites is a common disease between humans and animals. Therefore, the current study aimed to investigate the prevalence of scabies disease as a disease caused by an external parasite is the mites as well as the study of other important diseases caused by viruses and Insecta such as yellow fever and myiasis. 40825 sheep, 940 cow and 2285 buffalo were examined and the infected animals were diagnosed in the laboratories of the veterinary hospital in Thi-qar governorate for the period from January to October 2017.  The incidence of scabies in sheep, cows and buffalo were 65.03%, 53.64% and 38.03% respectively. The incidence of yellow fever in sheep, cow and buffaloes was 50.81%, 55.25% and 44.67% respectively. There were also significant differences between infection percentage according months of year. The incidence of myiasis among sheep, cow and buffaloes was 94.30%, 70.43%, and 70.95% respectively with significant differences between infection according months of year for all animals examined.Keywords: Infectious animals, External parasite, Scabies, Yellow Fever, Myiasis.
Ethnopharmacology of The Tengger Tribe Society: Inventory Study of The Use of Medicinal Plants Hadi Prayitno; . Ari P; Erwin Nur Rif’ah; Dewi Rokhmah
Journal of Global Pharma Technology Volume 12 Issue 09 (2020) Sept. 2020
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The Tenggerese community is a community that inhabits the area commonly called "Tengger village". The community trust of the Tengger Tribe towards Mount Bromo and Mount Semeru is very large, so that it has created a close relationship between the people of Tengger Tribe and nature. The ethnobotany study is expected to not only be a documentation of traditional knowledge in the use of plants for subsequent generations, but also as one of the capital in the development and preservation of biological natural resources, especially for the use of traditional medicines in the Tengger tribe. This research is qualitative research. The results of the study indicate the occurrence of the Tengger Tribe Knowledge, Beliefs and Local Wisdom Inventory in Probolinggo Regency, with the decline in Tengger tribe knowledge and belief in the nature and benefits of medicinal plants. This was caused by the success of the health program by the government so that many residents took advantage of modern medicine when they were sick, Tengger Tribe who lived in Lumajang Regency showed the use of plants in every religious or cultural ritual or treatment, based on the teachings of their ancestors which is often done in the community around the informants from generation to generation. The Tengger tribe who lives in Pasuruan Regency shows that the rituals have been carried out from generation to generation and there are no special rituals when using the medicinal plants. The perceptions, attitudes and behavior of the community regarding the Tengger tribe medicinal plants in Probolinggo Regency showed a mediocre attitude because they had rarely used it as well as other forms of behavior, namely informants had not used the medicinal plants anymore, except for a few the older ones in the remote Tengger Mountain.In Lumajang, the type of traditional medicine in the Tengger tribe is actually still perceived and responded to quite positively by informants doing treatment in the traditional way within certain limits. However, they are more open to the patterns of modern medicine, especially among the younger generation. in Pasuruan Regency, residents perceive medicinal plants as plants that can treat a disease that they know from their ancestors before. Inventory of medicinal plants in the Tengger tribe domiciled in Probolinggo Regency there are at least 3 types of plants that are still used for medicinal purposes in the face of health problems such as red ferns, fennel and saffron plants. Whereas in Lumajang Regency uses include sugar cane plants, dlingu plants and banana plants for cases of health problems. The use of medicinal plants in Pasuruan Regency includes: dringu plants, black mustard greens, fennel, besides that there are also castor plants, muscle flour, ciplukan fruit, amethyst plants and ganjan plants. Keywords: Ethnopharmacology, Tengger Tribe, Society , Inventory Study, Medicinal Plants
The Relationship between Emotional Intelligence and Patients’ Demographic Characteristics referred to Iranshahr University of Medical Sciences hospitals in 2014 Masoomeh Shahnavazi
Journal of Global Pharma Technology .
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Background and objective the patients under hem dialysis treatment experience so much stress associated with care plans and limitations in social communication. Because of the significant role of emotional intelligence on improving mental health and the fact that there is no precise information of hem dialysis patients’ emotional quotient, the investigation of emotional intelligence in this context as well as designing and implementation of effective training programs can be regarded as a basis for enhancing this important variable. Method this is a descriptive-correlation study conducted in 2014 of the patients under hem dialysis treatment took part in the study according to the complete enumeration method and the required criteria. The data collection instruments included individual particulars and Cyberia-Shrink Emotional Intelligence questionnaire. The data were analyzed by using descriptive and analytical statistics (mean and standard deviation), analysis of variance (ANOVA), independent T-test, and Schaffer test through SPSS 16.  Findings the mean and standard deviation of emotional intelligence total score were43.99±10.50. The results indicated that there is a statistically significant relationship between emotional intelligence and gender (p = 0.03), marital status (p = 0.02), smoking status (p = 0.001), and economic condition (p = 0.04) in different age groups (p = 0.03). There was also a statistically inverse relationship between emotional intelligence mean score and systolic and diastolic blood pressure (P = 0.001and P = 0.03, respectively). Furthermore, there was not a statistically significant relationship between emotional intelligence and the variables ‘weight, educational level, occupational status, and place of residence’.  Conclusion with regard to the relationship between some demographic characteristics and emotional intelligence, designing and implementation of effective training programs can improve this crucial element in patients with chronic kidney disease and under hem dialysis treatment.Keywords: Emotional intelligence, Chronic kidney disease, Hem dialysis, Demographic characteristics.
Synthesis, Characterization, Antibacterial and Antifungal Activity of Some Bis (1, 3, 4-oxadiazole) Polymer Nawar Jamal Abdul Rada
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Pyridine-2, 6-dicarbohydrazide comp (2) was synthesized from ethanolic solution of diethyl pyridine-2, 6-dicarboxylate comp (1) with excess of hydrazine hydrate. Newly five polymers (P1-P5) were synthesized from reaction of pyridine-2, 6-dicarbohydrazide comp (2) with five different di carboxylic acid in the presence of poly phosphoric acid (PPA). The antibacterial activity of the synthesized polymers was screened against some gram positive and gram negative bacteria.  Antifungal activity of these polymers was evaluated in vitro against some yeast like fungi such as albicans (candida albicans). Polymers P3, P4 and P5exhibited highest antibacterial and antifungal against all microorganisms under test.Keywords: Bis 1, 3, 4-oxadiazole, Polymer, Antibacterial, Antifungal.
Training Complexity in Accordance with the Change in the Radius of the Jogging Curve in the Development of Some Physical Abilities and Mechanical Variables to Accomplish 200 Meter for Youth Mazin Anhair Lami
Journal of Global Pharma Technology .
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The objective of the research was to identify the effect of the special exercises to increase the training complexity according to the change in the radius of the jogging curve in the development of some physical abilities and biomechanical indicators and the achievement of running 200 m for youth. The sample of the research was short distance sprinters for the youth group within the clubs of Wasit province for the sports season 2017-2018. (12) Runner, the researcher used the experimental method of the two equal groups. And a set of standardized tests to measure physical capacity. The biomechanical variables were measured using cameras with a speed of 240 r / s and then analysis of the films by Kenova. The exercise was implemented by three training units per week with a total of (24) units, The tests were carried out by the pretest and post conditions and procedures and method of work, the researcher used the statistical bag (SPSS) to reach the test hypothesis of the search, a set of results to compare the experimental group and control were all significant results for the benefit of the experimental group in the brother except for the variable speed, the results were not significant.Keywords: Training complexity, Jogging curve physical abilities and mechanical variables.
The Effect of the Use of Semicircular Device to Learn the Performance of the Two Stages of Planting in the Box and Raise the Jump Pole for Female Students Mohammed Naji Shaker Abugneam
Journal of Global Pharma Technology Volume 11 Issue 6.
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The study included the design, manufacture and use of a semi-circular circular mechanical device. Mechanisms were used to learn the technical stages of performance by jumping the pole for female students. It was installed on the ground. And thus helped the students to perform easily as the effectiveness of bowel jump needs physical and motor abilities in addition to the correct technical performance as well as the general neuromuscular consensus according to the paths of movement, especially for students .The exercise was applied to the device from the group of experimentation Of term (6 weeks) by two units learning at a rate of 12 educational units then it was compared with the control group in reserving the technical performance of the digital level as statistical results showed experimental superiority over the control.Keywords: Design, Educational device, Jumping and learning.

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