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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 8 Documents
 1 
Search results for , issue "Volume 09 Issue 09" : 8 Documents clear
Usage of Mobile Applications at Night and its Association with Sleep Pattern and Academic Performance of the Medical Students of UniKL-RCMP, Ipoh, Malaysia ATM Emdadul Haque
Journal of Global Pharma Technology Volume 09 Issue 09
Publisher : Journal of Global Pharma Technology

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Abstract

Background: Smartphone has become a mainstream medium, in the healthcare setting because of quick access to medical information, enhance students’ learning in a clinical environment and increases knowledge score. Therefore, this research was performed to determine if there was an association of the mobile applications usage at night on sleep pattern and academic performance of the medical students of UniKL RCMP. Aim: This study was done to determine the relationship between socio-demographic factors with 3 elements, which are mobile application usage, sleep quality and quantity and academic performance. Methods: This cross-sectional study involved Year-2 till Year-5 medical students of UniKL RCMP. The sample size was calculated to be 214 students with 95% confident level, by using Opine application. The study was conducted from December 2016 to January 2017. The quota sampling method was used. A set of questionnaires were developed and computed as the variables of this study. Statistical analysis was done in SPSS 21 using appropriate statistical test, p<0.05 was considered as significant. Results:  Out of 300 only 215 questionnaires were returned.  100% of the current study respondents use a smartphone. There was a correlation between average total time smartphone apps used before sleep at night and feeling tired after waking up in the morning. This study result showed that usage of smartphone apps during class could lead to losing of attention. Conclusions: There were a correlation between mobile apps usage at night on sleep pattern. The heavier the usage of smartphone apps, the more sleep quantity and quality goes down. Though, students’ academic performance was not significantly associated with the use of mobile apps. 
High Expression F2-Isoprostan (F2-IsoP), High Sterol Regulatory Element Binding Protein-2 (SREBP-2) and Low 2-Methoxyestradiol (2-ME) On Placenta Tissue as a Risk Factor of Pre-Eclampsia Jaya Kusuma AAN; Suwiyoga K; Mantik AN; Sukrama DM
Journal of Global Pharma Technology Volume 09 Issue 09
Publisher : Journal of Global Pharma Technology

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Abstract

To date, pre-eclampsia (PE) still a problem of Maternal Fetal Medicine related to high incidence, maternal and neonatal morbidity and mortality. Pre-eclampsia is caused by pregnancy; however, the mechanism has not been established so it is still a disease of theories. This relates to differences in treatment, resulting in different ways of prevention and output of PE itself. Recently, the role of F2-IsoP ,SREBP-2 and 2-ME was suspected to be very important in the mechanism of the PE. Meanwhile, the placenta acts as a source regulatory protein production, so that the material of this study was taken from placental tissue. The study objective was to prove the high F2I-soP, high SREBP-2 and low 2-ME expression in the placenta as risk factors for PE Case control study has been conducted in the department of obstetrics and gynecology Sanglah Hospital with 62 samples in 2015. The case group consisted of 31 mothers with PE and control groups consisted of 31 non-PE mother. The study material is a placental tissue. F2-IsoP and SREBP-2 expression study was performed using immunohistochemistry and 2-ME with ELISA techniques in Pathobiology Laboratory Faculty of Veterinary Medicine Udayana University. Data were analyzed with chi square test and discriminant using SPSS. The statistical test results are presented in tabular form and narrative. In this study, it was found that high expression of F2-IsoP increased the risk of PE  4 times higher (OR = 4.44; 95% CI = 1.53 to 12.94; p = 0.005) ; high expression of SREBP-2 increased the risk of PE 8 times higher  (OR = 8.19, CI95% = 2,311 to 29.073; p = 0.001) and low expression of 2-ME increased the risk of PE 5 times higher (OR = 5.23; CI95% = 1.75 to 15.55; p = 0.002). On the discriminant test, we obtained contributing risk factor for the occurrence of PE were SREBP-2, F2Isop and 2-ME (p = 0.002) respectively. Conclusion, high F2-IsoP expression, high SREBP-2 expression and low 2-ME expression in placenta were risk factors for PE. The most dominant risk factor of PE mechanism was SREBP-2.Keywords: Pre-eclampsia, F2-Isoprostane, Sterol Regulatory Element Binding Protein-2, 2-Methoxyestradiol.
Perception on the Use of Plastinated Specimen in Anatomy Learning Among Preclinical Medical Students of UNIKL RCMP, Malaysia ATM Emdadul Haque
Journal of Global Pharma Technology Volume 09 Issue 09
Publisher : Journal of Global Pharma Technology

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Abstract

The scarcity of cadaver donation nowadays, consequently, the availability of fresh specimens will be drastically diminished. Plastinated specimens have been introduced as a supplement but are still not widely used in Malaysia.  This study aims to assess the knowledge on plastinated specimens and to determine the perception of preclinical medical students of UniKL RCMP about the use of plastinated specimen in studying anatomy.  A cross-sectional study was done on 143 preclinical medical students of UniKL RCMP using a simple random sampling method. A structured, self-administered questionnaire was used to collect socio-demographic data and information regarding perception on the use of plastinated specimen.  No significant association was found between gender and level of perception (p=0.458) although male students had a slightly better perception level than female students.  Regarding the relationship between gender and perception score, the mean of perception score was found to be higher in male than in female students but the mean difference was found to be statistically not significant (p=0.427).  Study on the association between year of study and the level of perception showed that the number of Year-II students with good perception was higher than that of Year-I students (p=0.006). On testing the relationship between year of study and perception score, the mean of perception score of Year-II students was found to be higher than Year-I students with the mean difference of 2.068 (p=0.002). Since the perception score toward the use of plastinated specimen for learning of anatomy was only an average among the preclinical MBBS students of UniKL RCMP and the Year-II students were having a better perception than the Year-I students, more frequent and longer exposure to the usage of plastinated specimens in learning anatomy should be encouraged. The increasing difficulty of obtaining donated cadavers experienced in many parts of the world propagated the use of plastinated specimens as a supplementary educational tool will open a new era in the teaching and learning of anatomy.KEYWORDS: Perception, Anatomy Learning, Preclinical Medical Students, UNIKL RCMP, Malaysia.
Empathy Level among Dental Students of Bangladesh Utilizing the Cambridge Behavior Scale Mainul Haque
Journal of Global Pharma Technology Volume 09 Issue 09
Publisher : Journal of Global Pharma Technology

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Abstract

Background: Empathy is the capacity to appreciate what another individual is feeling and suffering from within the other individual's setting or orientation, i.e., the capacity to accommodate individuality in another's shoes. Thereafter, empathy permits an individual to intermingle efficiently in the community. Then empathy acts as superglue of the universes of discourse, pulling us to support others and end from hurting others. Methods: This was a cross sectional study. The study populations were Dental students of Dhaka Dental College and Mandy Dental College, Dhaka, Bangladesh. Data was collected early part of 2017. The universal sampling method was adopted. Cambridge Empathy Scale Questionnaire was utilized for the data collection. Results: There was no statistically significant (p=0.079) difference observed in empathy level between male (38±9.1) and female (39.8±8.6). However statistically significant (p<0.001) differences were observed between public and private dental schools. The study found that 83.4% (297) and 16.6% (59) of SP had good and poor level empathy respectively. Conclusions: Empathy is imperative in the physician-patient rapport. Females scored higher empathy level than their male counterparts.  Additionally, empathy level was higher in Year-I than other years of study.Keywords: Empathy, Dental Students, Bangladesh.
Outpatient Educational Environment of Dental Medical Colleges of Bangladesh Utilizing Acleem Questionnaire Mainul Haque
Journal of Global Pharma Technology Volume 09 Issue 09
Publisher : Journal of Global Pharma Technology

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Abstract

Background: The learning environment as: ‘a social system that includes the learner (including the external relationships and other factors affecting the learner), the individuals with whom the learner interacts, the setting(s) and purpose(s) of the interaction, and the formal and informal rules/policies/norms governing the interaction’ [2]. Educational environment both academic and clinical, are substantial elements carrying out medical students’ attitudes, knowledge, skills, progression, behaviors and achievements Methods: This was a cross sectional study. The study participants were Dental students of Dhaka Dental College and Mandy Dental College, Dhaka, Bangladesh. Data were collected in early 2017. The universal sampling method was adopted. ACLEEM validated instrument was utilized for the data collection. Data were using SPSS Version 21. Results: The response rate was 100%. The total study population was 134. Among the current SP 32.8% (44) and 67.2% (90) were male and female respectively. The reliability and Validity of the Questionnaire regarding local context were Cronbach’s alpha 0.939 and convergent validity -0.013-0.682 There were no statistically significant (p>0.05) differences observed between sex and dental colleges in the domain of Clinical Teaching, Clinical Training and Total when analyzed with an independent t-test. Conclusions: The ACLEEM instrument was valid and reliable to measure ambulatory educational environment for Bangladeshi for Dental School. Most of the study participants had positive perception regarding their education environment.Keywords: Acleem, Dental colleges, Bangladesh.
Characterization and Evaluation of Antioxidant activity of Crataeva magna Lour (DC) RADHA krishnan meera
Journal of Global Pharma Technology Volume 09 Issue 09
Publisher : Journal of Global Pharma Technology

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Abstract

Objective: The present study was designed to investigate the anti-oxidant activity of the ethanolic extract of Crataeva magna Lour DC. The root bark of Crataeva magna Lour DC belonging to family Capparaceae is used in anti spasmodic, hypotensive, anti-inflammatory, hypoglycemic, anti protozoal, analgesic purposes.Methods: The ethanolic extract was evaluated by TLC and the antioxidative potential of ethanolic extract of Crataeva magna Lour DC was evaluated using 1,1-Diphenyl-2-Picrylhydrazyl (DPPH), hydrogen peroxide and xanthine oxidase inhibition assay.Results: The ethanolic extract of Crataeva magna Lour DC exhibited highest level of antioxidant activities. The ethanolic extract of Crataeva magna Lour DC showed up to 76% inhibition of DPPH free radical at 517 nm at high concentration of 1 mg/ml. The in-vitro xanthine oxidase inhibition of root ethanolic extract revealed significant (69%) inhibitory activity at 30 µg/ml and it compared with the standard drug quercetin which showed 70% inhibition at 30 µg/ml. In hydrogen peroxide scavenging activity the test extract shows 26% of inhibition when compared to the standard ascorbic acid.Conclusion: The presence of strong antioxidant activity of ethanolic extract of Crataeva magna Lour DC can be a great scope for further studies on this plant regarding its antioxidant potentials.Keywords: Root bark of Crataeva magna Lour DC, TLC, Antioxidant activities. 
An Update on Solubility Enhancement Methods for BCS Class -II Drugs Vamshi Krishna Tippavajhala
Journal of Global Pharma Technology Volume 09 Issue 09
Publisher : Journal of Global Pharma Technology

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Abstract: To attain the anticipated concentration of a drug in the systemic circulation in order to exhibit the pharmacologic response, solubility of the drug plays a critical role. Key research problems faced during formulation development of various drugs owe to their low aqueous solubility. About 40% of NCEs are unsuccessful in reaching their therapeutic range mainly due to their solubility issues. In this context, this review article details various solubility enhancement techniques and their application mainly to address this poor solubility of various BCS class-II drugs. Keywords: Solubility Enhancement Methods, BCS Class-II drugs.
LEPROSY DETECTION USING IMAGE PROCESSING AND DEEP LEARNING Suresh Kumar; HARSHIT Jain; SRIVINAYAK CHAITANYA ESHWA
Journal of Global Pharma Technology Volume 09 Issue 09
Publisher : Journal of Global Pharma Technology

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Abstract

Leprosy, generally called as Hansen's ailment, is an enervating and ceaseless bacterial malady. As indicated by World Health Organization's report, there were 189,000 uninterrupted occurrences of Leprosy in 2012 with 230,000 new conclusions. Though it is reparable at later stages, an early conclusion expects nerve deliberation and the inadequacies it causes. The makers thusly put forward a Convolutional Neural Network based building for Leprosy damage affirmation. To set up the framework, researchers and scientist use DermnetNz datasets close by web scratched pictures to finish a best accuracy of 91.6% on a dataset split into 60% of get ready pictures, 20% of pictures are used for cross endorsement and 20% for testing of the results.

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