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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 69 Documents
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Search results for , issue "Volume 10 Issue 10: 2018" : 69 Documents clear
Comparison between Some Bacteria and Fungi for Biodegradation of Glyphosate Herbicide in some Agriculture Soil in Iraq Faiza Kadhim Emran
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
Publisher : Journal of Global Pharma Technology

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Abstract

Glyphosate is a compound used as herbicide in the control and killing of grasses and herbaceous plants. It can be used in agriculture to prepare fields before planting during crop development and after crop harvest. Because of its toxicity to non-target organisms, there is need to decontaminate glyphosate from contaminated soils and bioremediation is a very useful alternative to conventional cleanup methods. The success of this will depend on isolating bacteria and fungi with the ability to degrade glyphosate in a changing environment. The abilities of two bacterial species Aeromonassobraia and Acinitobacter hemolyticus and three fungal species Aspergillu niger, penicilium notatum and Rhizopus sp. to degrade glyphosate herbicide under varying environmental conditions were evaluated in this study. The isolates were screened for glyphosate utilization using mineral salt medium containing glyphosate as carbon source. Two bacterial isolates were tested for their ability to biodegradation of glyphosate in liquid medium identified by Vitek compact system. Three fungal isolates were tested for their ability to biodegradation of glyphosate in liquid medium CzapekDox  and  Potato Dextrose agar (PDA).The two bacterial isolates, Aeromonassobraia and Acinitobacter hemolyticus and three fungal isolates, Penicillium notatum, Aspergillus niger, and Rhizopus sp., showed the capacity to utilize glyphosate efficiently and were therefore used for further biodegradation studies. The optimum conditions (incubation period, temperature) for biodegradation of glyphosate were examined. The obtained results indicated that the best incubation period was after 7 days for Aeromonassobraia while the best incubation period was after 9 days for Acinitobacter hemolyticus in mineral salt medium.  Favorite temperature was 450C for both bacterial isolates. Microbial growth during the study was monitored by measuring the optical density at 660 nm. This study showed that Aeromonassobraia and Acinitobacter hemolyticus exhibited a high capacity to efficiently degrade glyphosate under the environmental conditions studied. The obtained results indicated that the best growth was Aspergillus niger after 15 days while the weak growth was Penicillium notatum after 15 days in Czapek Dox and Potato Dextrose agar (PDA).  Fungal growth during the study was monitored by observed rang density growth. This study showed that Aspergillusniger best capacity to efficiently degrade glyphosate under the 50,100 mg/l. Other concentrations (200,300mg/l) inhibit growth for all fungal isolate. Thus, the organisms can be exploited for biodegradation of glyphosate.Keywords: Bacteria, Fungi, Biodegradation, Glyphosate, Herbicide.
The Impact of the use of Innovative Aids to Improve Some of the Kinetic Abilities and Learn the Skill of Receiving the Service of Volleyball Hamida Obaid Abdulamir
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

Volleyball is a group of games that have spread widely and evolved from a game of recreation and leisure time to a game of competition for the higher levels and require the highest degrees of performance and skill and also require high fitness for the coach or the teacher to strive to achieve a good level of performance must To prepare the learner from all aspects of physical and skill, as well as to pay attention to the development of physical and motor abilities through the use of innovative aids to improve the level of learning to the good performance and level required. The sample of the study consisted of (30) female students who were randomly selected by drawing lots of (38) female students after the exclusion of female students of the game and the students of the experimental experiment were divided into two equal groups by lottery method, the control group and the number of (15) students and the experimental group (15).Before the implementation of the vocabulary of the educational curriculum, the researchers investigated the homogeneity of the research sample in the variables related to the morphological measurements (height, weight, age) as well as the motor abilities and technical performance of the volleyball receiver reception skill. The skewness value is limited to (± 1), which means that the sample is distributed naturally, indicating its homogeneity.Through the results, the most important conclusions were reached:Innovative assistive devices have a positive impact on the improvement of motor abilities (flexibility, balance, agility, accuracy) of the skill of receiving female students' volleyball.Innovative aids have a positive impact on learning the skill of receiving female students' volleyballExercise using innovative aids has had a greater impact than the teacher's approach to improving motor abilities (flexibility, balance, agility, accuracy) and learning the skill of receiving volleyball for female students.The chosen methods are commensurate with the nature of the sample, which helps to learn the skills in question.Keywords: Innovative aids, Kinetic abilities, Learn the skill of receiving the service and volleyball.
Nano - Structured Hesperidin: Evaluation the Antioxidant Activities In Vitro Ghassan M. Sulaiman
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

Hesperidin from citrus peels is known to have anti-inflammatory, vaso-protective, hypo-lipidemic, anti-allergic, anti-carcinogenic and antioxidant actions. Current study was designed to evaluate the antioxidant capacity of hesperidin and hesperidin nanoparticles by using simple in vitro free radical scavenging system including, DPPH free radical-scavenging, hydrogen peroxide scavenging and Resazurin dye scavenging activities. Hesperidin nanoparticles showed strong scavenging effects against DPPH, hydrogen peroxide and Resazurin dye, and this effect was more potent than pure hesperidin. The scavenging activity of hesperidin nanoparticles was concentrations dependent, in the range of 100-400 µg mL-1showing a maximum activity of 80% at 400 µg mL-1in similar way to Vit.C which was used as positive control. In conclusion, this work displayed that hesperidin exhibited antioxidant activity and could be considered as a source of antioxidants from nature.Keywords: Hesperidin nanoparticles, Antioxidants, Resazurin, DPPH, Hydroxyl.
The Effect of Special Visual Exercises in the Development of Visual Tracking and the Accuracy of Spike in the Volleyball for Young Players Bassem Hassan Ghazi
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

The Aims of Research toPreparation of visual exercises, especially in the development of visual tracking and the accuracy of the spike of the volleyball young players.To identify the impact of exercise visual especially in the development of visual tracking and the accuracy of the spike of the volleyball of young players.The Hypothesis wasSpecial visual exercises have a positive effect on the development of visual tracking and the accuracy of the volleyball spiking of young players.As for the research method, the researchers chose the experimental approach as the appropriate method to solve the research problem by designing the experimental and control groups with the tribal and remote tests as it fits the nature of the research problem.The sample of the research was chosen from the research community represented by the young players in the volleyball of the middle region (3 clubs) in Iraq at the age of 17-19 years and the number of (36) player has been selected two clubs, including the number of (20) player after the expulsion of the player prepared randomly by lot to represent the two groups Experimental and control of the sample of the search and the reality of (10) player for each group.The Researchers ConcludedAn evolution in visual tracking and accuracy of the volleyball team's spikein volleyball skill.There is a preference for the experimental group in the tests of the dimension of visual tracking and the accuracy of spiking in the volleyball.The various special exercises developed by the researchers contributed to the development of visual tracking and the accuracy of the spiking skill.The recommendations wereThe need to use special visual exercises to develop the visual tracking of players, especially young people.The need to use special visual exercises to increase the accuracy of the skill of spiking.The need to use special visual exercises to increase the excitement and excitement of young people and increase their motivation for training.Keywords: Visual exercises, Accuracy, Spike and volleyball.
The Extent to Which Some of the Infant Formulas Available in Iraqi Markets Conform to the Standards and Meet the Requirements of Ideal Infant Growth Mohanad Abbood Alhamid
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

This study was conducted in the laboratories of the College of Agriculture \ University of Kufa and the laboratories of the College of Food Sciences \ University of Al-Qasim Green. To determine the extent to which the specifications of different samples of infant milk formulas available in the local markets of Najaf province meet the standard specifications, meet the requirements of the ideal growth of Infant, and compare them with the overall composition of breast milk. Four replicates of different production batches were used for each model of infant formula. Nactalia1, Dielac1, Evolac1, Celia2, Dielac2 and Sunnybaby2.The results showed a decrease in the amount of energy processed by the milk formulas Dielac1, Celia2 and Sunny baby2, which were 65.48, 63.27 and 65.78 kcal / 100 ml, respectively, compared to the amount of energy provided by the mother to her infant. The amount of protein in all Infant milk formulas with genetic fructose intolerance especially during the first four months of life. It was also observed that the percentage of whey protein in the milk formulas Dielac1, Evolac1 and Dielac2 was similar to that in cow's milk at 17%, 20% and 16%, respectively. But increased to 25% in Celia2 milk and were close to the proportion of breast milk in the milk formula of Sunnybaby2 and Nactalia1 48% and 52%, respectively. It was also found that both mothers and experts accepted all infant milk formulas under study.Keywords: Infant formula, Nitrogen distribution, Sensory evaluation.
The Effectiveness of the Differentiated Education Strategy According to the two (Sensory-intuitive) Patterns in the Development of the Skills of Defensive Performance in the Volleyball for Students Ali Hussein Said Al-Moussawi
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

The progress that covered all areas including the sports field, and in many countries of the world was not coincidental, but adopted those countries many of the elements of progress, and that sport is one of the most important aspects of life and the progress of countries to build human education, physical and mental and so that sport can achieve these goals Less time using modern teaching strategies, and it is known that the skillful defense performance of the student in volleyball is related to learning within the educational institution and is a measure to evaluate the level of skill and defense performance of the learner and scientific achievement, and this investigation largely thanks to the use of the process-based Educational methods and ways and means and activities that help students so, so it could be among the reasons attributed to them this weakness in the technically gifted defensive performance is the continuation of teachers in the use of traditional teaching strategy, despite its effectiveness in certain conditions and situations. The research community determines the students of the fourth stage in the Faculty of Physical Education and Sports Sciences University of Kerbala for the academic year (2017 - 2018) and through the results reached the following conclusions:The use of a distinct learning strategy according to the two modes (sensory-sensory) has an effective effect on the development of the aerodynamic skill of the students.The results showed that there is a preference for the use of a differentiated learning strategy based on the sensory-sensory pattern.Keywords: Education strategy, (Sensory-intuitive) patterns and defensive performance.
Assessment of Serum IL-2 and Immunohistochemistry Detection of IL-2 in Induced Hypothyroidism of Male Rats Abbas Abed Sharhan
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

This study was conducted to demonstrate the role of methanolic extract from Ficuscarica leaves in the treatment of   hypothyroidism disease which induced in male rats by carbimazole drug. Forty male rats were divided into five groups, eight for each. group I selected as a negative control  which primed orally with normal saline alone, group II served as a positive control and treated by carbimazole anti-thyroid  drug for six weeks ,while  group  III  was treated by plant extract ( 500 mg /kg, bw) for six weeks ,whereas the  fourth group IV was treated by carbimazole drug (5 mg) for six weeks to induce hypothyroidism   and then  treated by plant extract ( 500 mg /kg , bw)  for six weeks too. Finally the fifth V group was  treated by thyroxin drug (100 mg) for six week instead of plant extract.The results showed that a non- significant difference (P< 0.05) in the level of  IL-2 of  the fourth  group when compared  with the first group  , while the results revealed a significant increase when compared with the  second  group  ,whereas a significance decrease when compared with the third and fifth groups. The immunohistochemical sections of  rats thyroid gland  in the first , second and third groups revealed that weak expression of IL-2 immunopositive cells (brown cytoplasmic deposits) in thyroid sections, while rats thyroid gland in the fourth group  and fifth groups revealed that a moderate expression of  IL-2 immunopositive cells. In conclusion it is possible to use methanolic extract of Ficuscarica leaves in the regulation of immune response in hypothyroidism disease may due to the presence of phytochemical components that enhance the cellular immune response by increase the IL-2 production.                                                                                     Keywords: Hypothyroidism, Carbimazole IL-2, Immunohistochemistry, Ficuscarica, phytochemical components.  
Effect of Special Exercises in the Development of Special Endurance (Endurance Strength and Speed Endurance) for the Effectiveness of Running 400 Meters Class (CP 36) Hind Walid Kalaf
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

The sport of the disabled is one of the most important sports that have witnessed remarkable development in recent years, especially after the London Paralympic Games 2012, especially on athletics. In view of the close relationship between modern training theories and its practical, scientific and training aspects to achieve the best levels, Athletes in category (CP 36) The researcher noted the lack of interest in this category of training, which depends on the scientific basis in terms of physical tests that fit the possibilities and capabilities of the category (CP 36).Where the objectives of the research were determined:Prepare special exercises in the development of your endurance.Identify the impact of special exercises in developing the endurance force for an effective 400 meters.Identify the effect of special exercises in the development of endurance speed for the effectiveness of 400 meters for class (CP 36).Research HypothesesThere were statistically significant differences between the pre and posttests of the two experimental groups in carrying power for the effectiveness of running 400 meters.There were statistically significant differences between the post-test of the two experimental groups in carrying the speed of running 400 meters for the class (CP36).The researcher used the experimental approach to suit the nature of the research with two equal groups.The research community was selected from the elite players (ages 18-23) category (CP 36) with a running efficiency of 400 m. The number of players (10) was divided into two experimental groups randomly and with (5) players for each group.The Researcher ConcludedThe special exercises showed a clear development in the endurance of disabled players in the category of CP 36)The wide development was the result of the prevailing quality of the effectiveness of the speed of 400 meters.Keywords: Special exercises, Special endurance, Endurance strength and speed endurance.
Mixed Ligand Schiff Base Complexes of Some Metal (II) Salts: Preparation, Spectral Characterization and Antibacterial Screening Faeza Hasan Ghanim
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

Schiff base ligand (E)-2-((3-hydroxyphenylimno) methyl)-6-methoxyphenol has been synthesized from m-aminophenol and o-vanillin. The geometry of Schiff base has been determined on the basis of Micro elemental analysis (C.H.N), molar conductance. Mass,  1HNMR, FT-IR and UV-Vis spectroscopic techniques. Metal mixed ligand complexes for manganese(II),cobalt(II),nickel(II),copper(II),zinc(II) and cadmium(II) for Schiff base ligand and paracetemol have been prepared in the molar ratio 1:1:1 (M:L: Para), (M= Metal, (L)= Schiff base ligand and (Para) = paracetamol) have been prepared and identified by using flame atomic absorption, FT.IR and UV-Vis spectral methods, on other than magnetic properties and conductivity measurements. Their electrical conductance values indicate that all complexes are electrolytes. From   obtained data octahedral geometry were suggested with all prepared complexes. Schiff base ligand, paracetamol as well as metal (II) complexes were assayed by antibacterial activity against some pathogenic bacteria using disc diffusion method.Keywords: Schiff base, Paracetamol, Mixed ligand complexes, Antibacterial screening.
Synthesis and Spectroscopic Studies of Some Heterocyclic Compounds (Oxazepane -4, 7-Dione, Azetidin-2-one) Derived from 2-Chloro -1, 8-Naphthyridine-3-Carbaldyhyd and Studying their Bacterial Activity Khamaael M. Fayyadh
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

Some new 2-chloro -1,8-Naphthyridine-3-carbaldyhyd  (K1) has been synthesized using N-acetyl-2-amino pyridine with through Vilsmeier-Haack cyclization to  preparation the compounds of Synthesis of  3-chloro-4-(2-chloro1,8-Naphthyridine-3-yl)-1-phenylenazetidin-2-one by ring closer reaction through the reaction of the compound (K5-7) with chloro acetyl chloride in presence of drops of tri ethyl amine in 1,4-dioxane ,andas has been prepared (R) 2-(2-chloro1,8-Naphthyridine-3-yl)-1-phenyl-1,3-oxazepane-4,7-dione from reaction the compound (K8-10) with  of Malic anhydride ,The newly synthesized compounds were characterized by spectroscopic evidences such as IR and 1H NMR. The synthesized compounds were screened for their in vitro antibacterial activity, compounds were shown good activity.Keywords: 1, 8-naphthyridine, Vilsmeier-Haack, Azetidine, Oxazepane-4, 7-Dione.

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