cover
Contact Name
I Wayan Sudarsa
Contact Email
sudarsa@unud.ac.id
Phone
-
Journal Mail Official
globalpharmatechnology@gmail.com
Editorial Address
India
Location
Kota denpasar,
Bali
INDONESIA
Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 39 Documents
Search results for , issue "Volume 10 Issue 12." : 39 Documents clear
A Centralized Automated System of Monitoring Adverse Events of Medications- “Medreminder” Serikzhan Berdakhovich Sydykov
Journal of Global Pharma Technology Volume 10 Issue 12.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Research ObjectiveTo develop and test the methodology of the centralized automated system of monitoring adverse events of medications in the Republic of Kazakhstan.Research TasksThe analysis of the existing practice of monitoring adverse events of medication in the Republic of Kazakhstan, the identification of problems and the directions to improve the situation.Testing the models of an automated system collecting information about adverse events of medications and the evaluation of effectiveness of the developed system collecting information about adverse events of medications, identifying patients/consumers’ roles of Kazakhstan medical products in the system of pharmacovigilance.Keywords: pharmacovigilance, monitoring the safety of medications, patients, consumers, monitoring adverse events, “yellow card”, consumer reporting.
Pharmacokinetic Modification of Colon Targeted Delivery systems of Tegaserod Maleate based on Osmotic Technology R. Margret Chandira
Journal of Global Pharma Technology Volume 10 Issue 12.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Colon targeted delivery systems of Tegaserod maleate based on osmotic technology were developed. The developed systems consisted of osmotic core (drug, osmotic agent and wicking agent), coated with semipermeable membrane (spm) containing guar gum as pore former, coated core were then further coated with enteric coating to protect the system from acidic environment of stomach. the effect of various formulation variables namely the level of wicking agent (sodium lauryl sulphate), osmotic agent in the osmotic core, the level of pore former (guar gum) in spm, were studied on physical parameters and drug release characteristics of developed formulations. Tegaserod maleate release of drug is directly related to the level of pore former, wicking agent and osmotic agent. The drug release from the developed formulations was independent of pH.  The thickness of enteric coating could prevent formation of delivery pores before contact with simulated colonic fluid, but had no effect on drug release. Result of spm studies showed the formation of in-situ delivery pores in the membrane from where the drug release occurred, and the number of pores formed were directly related to the initial level of pore former (guar gum) in spm. the manufacturing procedure was found to be reproducible and formulations were found to be stable during 3 months of accelerated stability studies.
Effect of Various Anticoagulants on Ethinyl Estradiol and Levonorgestrel Analysis in Human Plasma in Vitro by Ultra Performance Liquid Chromatography Tandem Mass Spectrometry Yahdiana Harahap
Journal of Global Pharma Technology Volume 10 Issue 12.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Objective: This research objective is to evaluate the different types of anticoagulant to ethinyl estradiol and levonorgestrel analysis in plasma using ultra performance liquid chromatography tandem mass spectrometry. Method: Chromatography condition was obtained with Acquity® UPLC BEH C18 column (1.7 µm; 50 x 2.1 mm); mobile phase consisting 0.1% formic acid in water – acetonitrile under gradient elution ; flow rate of 0.3 mL/minute; column temperature of 40ºC; injection volume of 10.0 µL; 5-minute analysis time and prednisone as internal standard. Sample preparation used protein precipitation followed by liquid-liquid extraction. Results: There was a linear result ranging from 5-500 pg/mL concentration of ethinyl estradiol and 100-10,000 pg/ml concentration of levonorgestrel. There was no significant difference for stability and recovery of ethinyl estradiol and levonorgestrel in citrate, heparin, and EDTA plasma (p > 0.05; ANOVA). However, significant difference for peak area ratio (p < 0.05; Kruskal Wallis), between citrate, EDTA, and heparin plasma was observed. Conclusion: Citrate and heparin plasma analysis had better result than EDTA plasma analysis.Keywords: Ethinyl estradiol, Levonorgestrel, Prednisone, EDTA, Heparin, Citrate.
Effect of Sonication to Protein Extraction from Jackfruit Seed (Artocarpus Heterophyllus) Flour Nguyen Phuoc Minh
Journal of Global Pharma Technology Volume 10 Issue 12.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Ultrasound technology is growing rapidly in the field of research and development of non-thermal food processing methods. Jackfruit seeds are not only nutritive, but also tasty. The flour from seeds is a fruit residue featuring alternative protein, carbohydrate and fiber source. A wide range of ultrasound power, treatment temperature, treatment time, ratio of liquid: solid have been investigated. Optimum conditions for the extraction of protein were found to be: sonication power of 30 W/g, sonication time 3 min, sonication temperature 45oC and solid-liquid ratio of 2.0: 1.0, and the extraction time of 30 min. Ultrasound is one of the emerging technologies that were developed to reduce the cost and time of processing. It ensures the quality and safety of food products. The use of ultrasound can enhance the extraction process by increasing the mass transfer between the solvent and plant material. Ultrasound in the use of plant extraction has benefits in increased mass transfer, better solvent penetration, less dependence on solvent used, extraction at lower temperatures, faster extraction rates and greater yields of product.Keywords: Jackfruit, Protein, Extraction, Sonication.
Optimization of the Simultaneous Determination of Sitagliptin and Metformin, in Human Plasma by A Rapid HPLC Method Balamurugan K; Kirtimaya Mishra; Suresh R
Journal of Global Pharma Technology Volume 10 Issue 12.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Simple, rapid and reproducible methods were established for quantitative determination of Sitagliptin (SIT) and Metformin (MET) spiked with plasma using an Onyx C18 Monolithic column  connected with an Onyx C18 guard cartridge.  and PDA detection at 210 nm. The mobile phase was MeOH, ACN, 0.01mM KH2PO4 (pH 3.5±0.5), adjusted with freshly prepared 10% orthophosphoric acid.  was pumped at 0.492 mL/min. The method was linear between 0.5-2.5 µg/mL, statistically validated for its linearity, precision and accuracy. The precision was found to be less than 1% showing high precision of the assay method. It was found that the excipients in the commercial tablet did not interfere with the method. Developed method can routinely use for the estimation of SIT and MET related compounds from the dosage form spiked with plasma.
Sperm Detection in Congenital Ejaculatory Duct Cyst Repair: A Case Report Ahmad Ricardo Silalahi
Journal of Global Pharma Technology Volume 10 Issue 12.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Ejaculatory duct cyst is a very rare case. We report a 26-year-old man with primary infertility complaining of aspermia since before marriage, precisely since the first wet dream. General physical examination and hormonal levels were in normal values. The cyst was visualized through abdominal TRUS, MRI and abdominal ultrasound (USG). The sperm detection test was performed before and after repaired by TURED. Before repair, the sperm was absent at Cowper’s gland secretion, post orgasmic urine and post massage prostate. After repair, sperm was detected in cyst aspiration fluid and useful to distinguish ED cyst between the Mullerian duct and utriculus cyst. In addition, after one month post repaired, the sperm concentration, motility and morphology increased. The improvement of sperm quality is useful to determine the infertility program whether IVF, IUI or natural pregnancy.Keywords: Ejaculatory duct cyst, Male infertility, Sperm detection.
Green Chemistry, Characterization and Study of Medical Application Silver/ Polymer Nanocomposite Khalidah Khalaf Jabbar
Journal of Global Pharma Technology Volume 10 Issue 12.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Over the last few years, the green consistency over nanoparticles (NPs) the usage of drive into extracts has emerged as a hopeful methodology because of the fabrication of metal NPs (especially silver, copper, and riches NPs), so kind of it entails an easy, fast, low-cost, then environmentally pleasant bioprocess. The consistency atop nanoparticles through the use of the biochemical rejoinder regarding propulsion dust reply since page banish as regards but facile, quick & eco-friendly microwave assisted adjustment of doublet polymers polymethyl methacrylate & poly butyl methacrylate and joining nanocomposites Ag/Polymethyl methacrylate (Ag/PMMA) then Ag/ Poly butyl methacrylate (Ag/PBMA). The synthesized nanoparticles had been characterized through FT-IR, UV-visible, X-Ray Diffraction (XRD) afterward Transmission Electron Microscopic (TEM) studies. Nanocomposites, Scanning Electron Microscopy (SEM) and TG/DTA.XRD studies but TEM pictures evolved average particle quantity concerning synthesized nanoparticles 20 nm. Thermal lookup rose that standard hot regarding Ag/PMMA then Ag/PBMA nanocomposites reduced as it should be among pursuance with city related to Ag nanoparticles of the polymer matrix.Keywords: Green synthesis, Metal nanoparticles, Metal/ Polymer Nanocomposite, Medical Application
Knowledge on Cervical Cancer Prevention and Attitude towards Pap smear and HPV Vaccination among Women Attending a Health Clinic in IPOH, Malaysia Sandheep Sugathan
Journal of Global Pharma Technology Volume 10 Issue 12.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Objectives: Cervical cancer is the second most common cancer among women in Malaysia and is one of the leading causes of cancer mortality in women worldwide. This study was carried out to study the knowledge level regarding cervical cancer prevention and attitude towards Pap smear and HPV vaccination among women attending Greentown outpatient clinic in Ipoh, Malaysia. Methods: Data were collected using a structured questionnaire which included socio-demographic characteristics, knowledge of cervical cancer, Pap smear and HPV vaccination and attitude towards Pap smear and HPV vaccination from a sample of 100 women of age between 16 and 65 years, who were attending the Greentown outpatient clinic in Ipoh, Perak from 21st July to 8th August 2014.Results: Most of the participants were of the age group of 26 to 45 years (44%). Majority of the respondents had good knowledge of cervical cancer, Pap smear and HPV vaccination and showed good attitude towards Pap smear and HPV vaccination. Knowledge levels were significantly different in the different age groups. Attitude on Pap smear and HPV vaccination was significantly higher among higher education groups and employed groups. Conclusion: Age was significantly associated with knowledge levels on cervical cancer prevention and HPV vaccination. Education and occupation levels were significantly influencing the attitude of women regarding cervical cancer, Pap smear and HPV vaccination.
Analysis of Magnetic Resonance Image Segmentation Using Spatial Fuzzy Clustering Algorithm E. Udayakumar
Journal of Global Pharma Technology Volume 10 Issue 12.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The paper presents the MRI brain diagnosis support system for structure segmentation and its analysis using spatial fuzzy clustering algorithm. The method is proposed to segment normal tissues such as White Matter, Gray Matter, Cerebrospinal Fluid and abnormal tissue like tumor part from MR images automatically. The most of MR image are corrupted by artifacts which lead to affect the image processing for analysis of brain images. Due to this type of artifacts and noises, sometimes one type of normal tissue in MRI may be misclassified as other type of normal tissue and it leads to error during diagnosis.The proposed method consists of pre-processing using wrapping based curvelet transform to remove noise and modified spatial fuzzy C Means segments normal tissues by considering spatial information because neighboring pixels are highly correlated and also construct initial membership matrix randomly. The system also uses to segment the tumor cells along with this morphological filtering will be used to remove background noises for smoothening of region. The paper results will be presented as segmented tissues with parameter evaluation to show algorithm efficiency.   Keywords: SFCM, NN, GLCM, DWT, MRI, CT.
Health Promotion and Community Cadres’ Knowledge about the Medicine (DAGUSIBU) in the Community District of Yogyakarta, Indonesia Dyah Aryani Perwitasari
Journal of Global Pharma Technology Volume 10 Issue 12.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

DAGUSIBU is an acronym of to get, to use, to keep and to throw the medicine away appropriately in Indonesia. The Indonesia Pharmacist Association already launched this acronym to support the appropriate use of medicine. However, some efforts are needed to be conducted to understand about the dissemination of DAGUSIBU in community. This study is aimed to define the effectiveness of the health promotion in the increase of knowledge of the community cadres in one of community district in Yogyakarta, IndonesiaThis study used quasi experimental, one group pre-posttest design. The respondents were all community cadres in Muja Muju, Yogyakarta Indonesia. The health promotion with DAGUSIBU topic by the pharmacist was conducted as the health promotion media. The questionnaire was given to the respondents before and after the health promotion.We recruited 39 community cadres from Muja Muju Yogyakarta. Most of the respondents are female (94.9%), with the average of age is 54.5 years old. The community cadres’ knowledge increased significantly from 38.4 to 80.1 (p<0.001). Respondents’ characteristics, such as age, sex and education did not predict the increase of community cadres’ knowledge about DAGUSIBUThe health promotion of DAGUSIBU   conducted by pharmacist can improve the community cadres’ knowledge. This model can be used to disseminate DAGUSIBU effectively in community level.

Page 3 of 4 | Total Record : 39


Filter by Year

2019 2019


Filter By Issues
All Issue Volume 17 Issue 12 (2025) Dec. 2025 Volume 17 Issue 11 (2025) Nov.2025 Volume 17 Issue 10 (2025) Oct. 2025 Volume 17 Issue 04 (2025) April 2025 Volume 17 Issue 03 (2025) March 2025 Volume 17 Issue 02 (2025) Feb. 2025 Volume 17 Issue 01 (2025) Jan 2025 Volume 16 Issue 12 (2024) Dec. 2024 Volume 16 Issue 11 (2024) November 2024 Volume 16 Issue 10 (2024) October 2024 Volume 16 Issue 09 (2024) September 2024 Volume 16 Issue 08 (2024) August 2024 Volume 16 Issue 07 (2024) July 2024 Volume 16 Issue 06 (2024) June 2024 Volume 16 Issue 05 (2024) May 2024 Volume 16 Issue 04 (2024) April 2024 Volume 16 Issue 03 (2024) March 2024 Volume 16 Issue 02 (2024) February 2024 Volume 16 Issue 01 (2024) January 2024 Volume 14 Issue 05 (2022) May 2022 Volume 13 Issue 05 (2021) May 2021 Volume 13 Issue 04 (2021) April 2021 Volume 13 Issue 03 (2021) March 2021 Volume 13 Issue 02 (2021) Feb. 2021 Volume 13 Issue 01 (2021) Jan. 2021 Volume 12 Issue 12 (2020) Dec. 2020 Volume 12 Issue 11 (2020) Nov. 2020 Volume 12 Issue 10 (2020) Oct. 2020 Volume 12 Issue 09 (2020) Sept. 2020 Volume 12 Issue 08 (2020) Aug. 2020 Volume 12 Issue 07 (2020) July 2020 Volume 12 Issue 06 (2020) June 2020 Volume 12 Issue 05 (2020) May 2020 Volume 12 Issue 04 (2020) April 2020 Volume 12 Issue 03 (2020) March 2020 Volume 12 Issue 02 (2020) Feb. 2020 Volume 12 Issue 01 (2020) Jan. 2020 Volume 12 Issue 08 Volume 11 Issue 12 (2019) December 2019 Volume 11 Issue 11 (2019) November 2019 Volume 11 Issue 10 (2019) October 2019 Volume 11 Issue 09 (2019) September 2019 Volume 11 Issue 09: (2019) September 2019 Volume 11 Issue 08 (2019) Aug. 2019 Volume 11 Issue 07 (2019) July 2019 Volume 11 Issue 06 (2019) June 2019 Volume 11 Issue 05 (2019) May 2019 Volume 11 Issue 04 (2019) April 2019 Volume 11 Issue 03 (2019) March. 2019 Volume 11 Issue 02 (2019) Feb. 2019 Volume 11 Issue 01 (2019) Jan. 2019 Volume 11 Issue 2: 2019 Volume 10 Issue 12. Volume 11 Issue 6. Volume 10 Issue 12 (2018) December 2018 Volume 10 Issue 11 (2018) November 2018 Volume 10 Issue 10 (2018) October 2018 Volume 10 Issue 09: (2018) September 2018 Volume 10 Issue 08: (2018) August 2018 Volume 10 Issue 07: (2018) July 2018 Volume 10 Issue 06: (2018) June 2018 Volume 10 Issue 05: (2018) May2018 Volume 10 Issue 04: (2018) April 2018 Volume 10 Issue 02: (2018) Feb 2018 Volume 10 Issue 01: (2018) Jan. 2018 Volume 10 Issue 10: 2018 Volume 10 Issue 01 Volume 09 Issue 12 Volume 09 Issue 11 Volume 9 Issue 11 . Vol. 9 Issue 7 : 2017 Volume 9 Issue 10 Volume 09 Issue 09 Volume 09 Issue 08 Volume 9 Issue 07 Volume 09 Issue 05 Volume 09 Issue 04 Volume 09 Issue 03 Volume 09 Issue 02 Volume 08 Issue 11 Volume 08 Issue 07 Volume 08 Issue 06 Volume 08 Issue 05 Volume 08 Issue 04 Volume 08 Issue 03 Volume 08 Issue 02 Volume 08 Issue 01 Volume. 9 Issue 6 Volume 08 Issue 10: (2016) October 2016 Volume 08 Issue 09: (2016) September 2016 Volume 12 Issue 01 Volume 11 Issue 07 Volume 11 Issue 05. Volume 11 Issue 04. Volume 11 Issue 03 Volume 11 Issue 01. Volume 08 Issue 08 Volume 04 Issue 02: (2012) February 2012 Volume 03 Issue 06: (2011) June 2011 Volume 03 Issue 04: (2011) April 2011 Volume 02 Issue 10: (2010) Oct.2010 Volume 02 Issue 07: (2010) July 2010 Volume 02 Issue 05: (2010) May 2010 Volume 02 Issue 03: (2010) March 2010 More Issue