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PAMERI : Pattimura Medical Review
Published by Universitas Pattimura
ISSN : -     EISSN : 26865165     DOI : https://doi.org/10.30598/pamerivol5issue12023
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
PAMERI is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community research to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and also interesting case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures, treatment, or other health issues that is important for the development of health care system are also acceptable. Letters and commentaries of our published articles are welcome. Subjects suitable for publication include, but are not limited to the following fields of: Allergy and immunology Anesthesiology Cancer and stem cells Cardiovascular Cell and molecular biology Child health Dermato-venereology Geriatrics Histopathology Internal medicine Neuro-psychiatric medicine Ophthalmology Oral medicine Otorhynolaryngology Physical medicine and rehabilitation Physio-pharmacology Pulmonology Radiology Surgery including orthopedic and urology Women’s health Community or public health
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 7 Documents
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Search results for , issue "Vol 3 No 2 (2021)" : 7 Documents clear
HUBUNGAN JUMLAH LEUKOSIT DENGAN KEJADIAN PREEKLAMSIA DI RSUD DR. M. HAULUSSY AMBON TAHUN 2018 Ali Akbar R Kibas; Vina Z Latuconsina; Merlin M Maelissa
PAMERI Vol 3 No 2 (2021)
Publisher : Fakultas Kedokteran Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (255.837 KB) | DOI: 10.30598/pamerivol3issue2page78-83

Abstract

Preeclampsia is a toxemia in old pregnancy marked by hypertension, edema, and proteinuria. The etiology of disease is unknown, but there are several theories that have been forward, one of which is the theory of inflammation associated with leukocytes. The main of this study is to figure out the relations of leukocytes count in patients with preeclampsia in RSUD dr. M. Haulussy Ambon in 2018. This research is an analytic study with a cross-sectional research design. Sampling of the study used total sampling with a number of samples that met the inclusion and exclusion criteria of 62 patients consisting of 26 pregnant women with preeclampsia and 36 pregnant women without preeclampsia. The result using Chi-Square test showed that there was no significant relation of leukocyte count in preeclampsia (p=0,063).
PERBANDINGAN EFEK TERAPI TRANSCUTANEUS ELECTRICAL NERVE STIMULATION (TENS) DAN INFRA RED (IR) DENGAN INFRA RED (IR) DALAM PENGURANGAN NYERI PADA PENDERITA ISCHIALGIA DI RSUD DR. M. HAULUSSY AMBON Isabella Jeklin Barolla; Maureen J. Paliyama; Laura B.S. Huwae
PAMERI Vol 3 No 2 (2021)
Publisher : Fakultas Kedokteran Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (869.773 KB) | DOI: 10.30598/pamerivol3issue2page1-7

Abstract

Ischialgia is a condition of pain, weakness, burning, and tingling along the back of the leg caused by inflammation which causes irritation of the ischial nerve and direct compression on the nerve, causing motor dysfunction which is also often exacerbated by flexion of the spine, twist and bend to the side. Based on data from the WHO global health estimates technical paper, it shows that the prevalence rate of ischialgia is high enough for the overall presentation of disease presented. Globally, the prevalence of ischialgia at all ages reaches 8.2% and is the main cause of years lived with disability (YLD). Based on this, this study aims to compare the effects of transcutaneous electrical nerve stimulation (TENS) and infrared (IR) therapy in reducing pain in patients with ischialgia at RSUD dr. M. Haulussy Ambon 2020. This research is analytical based on secondary data taken from the patient’s medical records. The number of samples in this study were 80 patients who were taken using purposive sampling method. The results of this study showed that the use of IR therapy and combination therapy of TENS and IR is considered effective with a mean VAS value at the ti me of pre-test -(before therapy) of around 5.74± 0.83 (95% CI; 2.39 - 2.76) and the mean value on the post-test was 3.17±0.95 (95% CI; 2.39-2.76);The use of IR therapy was considered ineffective with a mean VAS value at the time of pre-test (before therapy) of about 5.75±0.74 (95% CI; 1.91-2.28) and a mean value on the post-test of 3.65±0.92 (95% CI; 1.91-2.28); and the use of TENS and IR combination therapy is considered effective with a mean VAS at pre-test (before therapy) of about 5.74±0.92 (95% CI; 2.84-3.31) and a mean value on the post-test of about 2,66 ± 0.67 (95% CI; 2.84-3.31).
HUBUNGAN RASIO KOLESTEROL TOTAL TERHADAP HIGH DENSITY LIPOPROTEIN DENGAN KEJADIAN SINDROM KORONER AKUT DI RSUD DR. M. HAULUSSY AMBON TAHUN 2018-2019 Nurul H D J F Ahmad; Irwan Irwan; Eka Astuty; Zulkarnain Zulkarnain; Indrawanti Kusadhiani; Is Ikhsan Hataul
PAMERI Vol 3 No 2 (2021)
Publisher : Fakultas Kedokteran Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (262.811 KB) | DOI: 10.30598/pamerivol3issue2page43-62

Abstract

Cardiovascular disease is one of the leading causes of death in the world. The primary cause of death in cardiovascular disease around the worldis acute coronary syndrome (ACS). Based on data from the World Health Organization (WHO) in 2015, cardiovascular disease causes 17.5 million deaths or about 31% of all deaths globally, and due to acute coronary syndrome is 7.4 million. This disease is estimated to reach 23.3 million deathsby 2030. ACS is an emergency heart disease that occurs due to rupture or erosion of the atherosclerotic plaque in the coronary arteries. The ratio of total cholesterol to high density lipoprotein (HDL) cholesterol or also known as the Cardiac Risk Ratio is a comparative number that can be used to detect the risk of developing ACS.The purpose of this study was to determine the relationship between the ratio of total cholesterol to high density lipoprotein and the incidence of ACS in RSUD dr. M. Haulussy Ambon in 2018-2019. This research was an observational analytic study with a cross sectional design. Using total sampling method there were 80 peoples included to the sample. The instrument used was medical record data. Datas were analyzed using the SPSS application with the chi square test. Theresult showed p=0,032 (p<0,05). Based on the data analysis, there wassignificant relationship between theratio of total cholesterol to high density lipoprotein (HDL) and the incidenceof acute coronary syndrome in RSUD dr.M. Haulussy Ambon in 2018-2019
SKABIES NORWEGIAN PADA ANAK DENGAN LUPUS NEFRITIS Amanda Gracia Manuputty
PAMERI Vol 3 No 2 (2021)
Publisher : Fakultas Kedokteran Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (283.077 KB) | DOI: 10.30598/pamerivol3issue2page84-90

Abstract

Introduction: Norwegian (crusted) scabies is one of the classic infectious variants of scabies. This variant is common in immunocompromised patients including autoimmune diseases who are taking long-term steroids. Method:We report a case of Norwegian scabies in a child with lupus nephritis.Case:A 15-year-old boy, weighing 40 kg with the chief complaint of black-red spots and thick scales on both fingers, pubic, armpit and body accompanied by itching especially at night. Complaints of night itching were also felt by the patient's mother. The patient had a history of lupus nephritis who was treated with long-term steroids. The results of microscopic examination of skin scrapings found adult mites, eggs and Sarcoptes scabiei schibala. The diagnosis of Norwegian scabies is based on anamnesis, physical and microscopic examination. Results: he patient was treated with 5% permethrin cream, 2-4 ointment 2x a day, cetirizine 1 x 10 mg per day for 2 weeks and education on maintaining personal and environmental hygiene gave healing to the patient. Conclusion: Norwegian scabies therapy is a combination of topical scabidal agents, keratolytic agents to facilitate drug penetration and antihistamines to reduce nocturnal pruritus and education provides clinical improvement and prevents recurrence.
PENGARUH STRES AKUT TERHADAP KADAR GULA DARAH MENCIT (Mus Musculus) DENGAN PERLAKUAN EKSTRAK ETANOL ALGA COKELAT (Sargassum sp.) Christy Sahetapy; Indrawanti Kusadhiani; Yuniasih M. J. Taihuttu; Jansye C. Penturi; Johan B. Bension; Vina Z. Latuconsina
PAMERI Vol 3 No 2 (2021)
Publisher : Fakultas Kedokteran Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.93 KB) | DOI: 10.30598/pamerivol3issue2page26-42

Abstract

Stress is a non-specific response in the body to conditions or conditions that occur as a result of exposure to stressors. High stress usually has a negative impact on the body, one of which is increasing blood sugar levels. Brown algae is one of the traditional marine plants and contains secondary metabolite compounds such as alkaloids, flavonoids, and steroids which are antidepressants so that they can prevent the increase in blood sugar levels. This study aims to determine the effect of acute stress on blood sugar levels of mice by giving ethanol extract of brown algae. This research is a true experimental research design with pre test and post test control group design. 30 mice were divided into normal control (KN), negative control (K-), positive control (K +) groups, ethanol extract of brown algae with a concentration of 2.5% (P1) and 5% (P2). The study was started by measuring the initial blood sugar levels in all groups, then groups K-, K +, P1, and P2 were given stress treatment with the FST method for 6 minutes for 7 days. Group K + was given alprazolam at a dose of 0.2 ml at 1 hour before treatment, while P1 and P2 were given brown algae at 30 minutes before treatment. After the treatment, it was followed by measurement of the final blood sugar level. The data from the observations were analyzed using the dependent T-test with a confidence level of 95%. The results showed that the post-test blood sugar levels in the P1 and P2 groups experienced an increase, but the increase was not significant. The results also showed that the significance values (2-tailed) in the P1 and P2 groups were 0.772 and 0.392 (sig> 0.05), meaning that it could be concluded that there was no effect of giving ethanol extract of brown algae on the prevention of increasing blood sugar levels after acute stress.
PENGARUH PEMBERIAN EKSTRAK ETANOL ALGA COKELAT (Sargassum sp.) TERHADAP HITUNG JENIS LEUKOSIT MENCIT (Mus musculus) PASCA DIINDUKSI STRES AKUT Reski Toding Allo Lebang; Vina Z. Latuconsina; Halidah Rahawarin; Ingrid Hutagalung; Parningotan Y. Silalahi; Samuel Maruanaya
PAMERI Vol 3 No 2 (2021)
Publisher : Fakultas Kedokteran Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2838.538 KB) | DOI: 10.30598/pamerivol3issue2page8-24

Abstract

Glucocorticoids are stress hormones that suppress normal immune responses by blocking Th1 cells. Glucocorticoids have an impact on decreasing the body's immune system and changes in leukocyte differentiation. Sargassum sp. is one type of brown algae that lives in the sea. Sargassum sp. contains metabolite compounds that are immunomodulatory. This study aims to determine the number of types of leukocytes in mice that are induced by stress and given ethanol extract of Sargassum sp. Pure experimental research design with post test only control group design. Thirty mice were divided into five treatment groups, namely the normal control group (KN), negative control (K-), positive control (K +), ethanol extract of Sargassum sp. 35% (P1) and 70% (P2). At K-, K +, P1 and P2 were given stress treatment with the FST (Forced Swim Test) method to see immobility time in mice. The treatment was given for seven days and on the 8th day the intracardial mice were taken. Observation of leukocytes from the blood smear of mice was carried out using a microscope with 1000x magnification. Observation data were analyzed by ANOVA. The results showed that the P1 group could reduce the percentage of neutrophils and monocytes but increase the percentage of lymphocytes, while the P2 group showed a decrease in the percentage of neutrophils, an increase in the percentage of lymphocytes, but could not decrease the percentage of monocytes compared to P1. The mean percentage of eosinophils and basophils did not change significantly, both in the treatment group and in the control group. However, statistical data shows no significant change between groups. So it can be concluded that stress treatment given to mice does not have a significant effect on the average percentage of monocytes, lymphocytes, neutrophils, eosinophils and basophils after being induced by stress.
HUBUNGAN REAKSI EMOSIONAL MAHASISWA SEMESTER PERTAMA DENGAN TINGKAT KELULUSAN PRAKTIKUM ANATOMI BERBASIS CADAVER Ayu Febriyanti Abbas; Vebiyanti Tentua; Johan B. Bension; Parningotan Y. Silalahi; Sherly Yakobus; Irwan Irwan
PAMERI Vol 3 No 2 (2021)
Publisher : Fakultas Kedokteran Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (332.607 KB) | DOI: 10.30598/pamerivol3issue2page43-62

Abstract

Emotion is psychological condition that supports a person to make or do something after a stimulus originating from within and outside him/her. First-year medical students habitually experience various emotional reactions and mixed feelings, when they got cadaver for the first time in the practicum room or surgery room. Based on data graduation got from the Medical Education Unit (MEU) of the Faculty of Medicine at Pattimura University, the level of effectiveness of anatomy subject from the 2014/2015 academic year to the 2016/2017 only reached 53,63% this figure shows that a small number of students are capable pass anatomy sub-alignment course. This research aims to describe the emotional reaction of the first semester students with a graduation level of cadaver-based anatomy practicum. This research is a quantitative analytic research with sectional approach. Amount of 142 respondent were obtained using total sampling for the all 2019 first semester students who participated in the second biomedical anatomysub-block of the 2019/2020 Academic Year. Retrieval of data using the cadaver student's emotional reaction dealing with questionnaire that has been validated. Based on the result of the study found that a mount of 31,2% of students who passed the anatomy practicum experience got the positive emotions, while 25% felt negative emotions. Then 68,8% and 80% of student who experienced positive and negative emotions were stated didn’t pass the test. These results showed that there was no correlation between emotional reactions and cadaver-based anatomical practicum graduation rates, with the calculated Chi Square amount=0.069 and p=0,793 at the significance of 0,050. So it can be concluded that there is no relationship between emotional reactions with the graduation level of cadaver-based anatomical practicum in 2019 first semester students of the Faculty of Medicine, Pattimura University.

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