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Medical and Health Journal
Published by Universitas Jenderal Soedirman
ISSN : -     EISSN : 28073541     DOI : https://doi.org/10.20884/1.mhj.2023.2.2.8053
Core Subject : Health,
Medicine & Pharmacology
Medical and Health Journal (EISSN. 2807-3541) is containing various articles/ manuscripts in the forms of research article, systematic reviews, case reports in the field of medicine focusing on basic medicine, clinical medicine, biomedical sciences, medical biotechnology, and public health. This journal is published by Universitas Jenderal Soedirman, Purwokerto, Indonesia.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 13 Documents
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Search results for , issue "Vol 4 No 1 (2024): August" : 13 Documents clear
KADAR ALPHA FETOPROTEIN (AFP) DENGAN PROFIL HbsAg PADA PASIEN KARSINOMA HEPATOSELULER DI RSUD PROF. DR. MARGONO SOEKARJO: SEBUAH STUDI CROSS SECTIONAL Yudiananda, Domas Shifa; Sulistyo, Hidayat; Wijayana, Kamal Agung
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12894

Abstract

Background: Hepatocellular carcinoma is 10-20% of all liver diseases in Indonesia. Detect the emergence of hepatocellular carcinoma in the early phase are needed, especially in patients with high risk, such as chronic hepatitis and cirrhosis of the liver by performing regular investigations (USG, CT Scan) and laboratory examinations (AFP, PIVKA II). Aim: To determine the correlation between AFP levels and HbsAg profile in Hepatocellular Carcinoma patients at Regional Public Hospital of Prof. Dr. Margono Soekarjo. Methods: The research method was analytic observational with cross sectional approach. This research uses samples from January-December in 2020. The sampling method of this research is Total sampling. Retrospective data retrieval of secondary data in the form of medical records of the research sample. The research subjects were Hepatocellular Carcinoma patients at Prof. Dr. Margono Soekarjo, totaling 30 people. Result: The mean of people with hepatocarcinoma was 22 men with a percentage of 73.33%, while 8 people were female with a percentage of 26.67%. The mean age of the subjects of this study was 49.5 years. Subjects who had reactive results on HBsAg examination were 21 people with a percentage of 70%. The mean AFP level of the subjects was 17379.37 with a standard deviation of 25968.78. Results of the Fisher test for the correlation between AFP and HbsAg profile in hepatocellular carcinoma patients had a significance value of 0.032 (p <0.05). Conclution: that there is a correlation between AFP levels and HBsAg profile in Hepatocellular Carcinoma patients at Regional Public Hospital Prof. Dr. Margono Soekarjo.
SKROFULODERMA PADA ANAK USIA 12 TAHUN DENGAN TUBERKULOSIS PARU, EFUSI PLEURA, PNEUMONIA DAN MALNUTRISI BERAT: LAPORAN KASUS Oliviany, Windy; Faisal, Imam Agus
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12976

Abstract

Background: Tuberculosis (TB) is a human disease caused by Mycobacterium tuberculosis. The disease primarily attacks the lungs, making pulmonary disease the most common symptom. Other organ systems frequently affected include the respiratory system, gastrointestinal (GI) system, lymphoreticular system, skin, central nervous system, musculoskeletal system, reproductive system, and liver. Scrofuloderma is rarely found in children. Late diagnosis and inappropriate treatment can lead to poor prognosis and complications. Case report: A 12 year old girl was referred from the regional hospital with complaints of shortness of breath since 3 days before admission. Accompanied by gasping, productive cough with difficulty coming out of phlegm, accompanied by an enlarged stomach and swollen legs, and fever fluctuating since 1 week before admission. Starting with a history of lumps on the neck since 6 months and have started tuberculosis therapy for 1 week before admission. Physical examination revealed multiple lymphadenopathy in the right and left cervical regions, decreased sounds in both lungs, and severe malnutrition. The results of a chest x-ray examination showed a massive pleural effusion. Laboratory results showed hypoalbuminemia, positive rivalta test in effusion fluid, and uncompensated respiratory acidosis. Management of this patient consists of oxygen, correction of hypoalbuminemia, antibiotics, anti-tuberculosis drugs, management of malnutrition, and water seal drainage (WSD). Conclusion: Although rare, scrofuloderma can be found in children. Therefore, collection of tissue specimens from specific extrapulmonary locations is necessary. Late diagnosis and inappropriate treatment can lead to poor prognosis and antimicrobial resistance. Delayed diagnosis and treatment will also cause complications such as the spread of infection to the lungs and other organs, severe malnutrition and stunting. Infections in the lungs and pleura can cause respiratory failure.
KORELASI KAPASITAS VITAL PARU DENGAN VARIABILITAS DENYUT JANTUNG MAHASISWI FAKULTAS KEDOKTERAN UNIVERSITAS JENDERAL SOEDIRMAN Abdullah, Rizky; Mustofa, Mustofa; Rahmawati, Indah
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12992

Abstract

The prevalence of cardiovascular disease in Central Java is high and the heart rate variability (HRV) among medical students is low. Heart rate variability is a non-invasive marker that describes the balance of the autonomic nervous system in the cardiovascular system. Heart rate variability is influenced by several factors. One of the factors that affect HRV is lung function. There is synchronization between the respiratory and cardiovascular systems. However, there is not much of explanation about the correlation between Force Vital Capacity and HRV. This Study aims to determine the correlation of FVC and HRV in female students of FK Universitas Jenderal Soedirman. This study is an analytic observational study with cross sectional approach. The number of subjects in this study were 31 female students who were determined by the consecutive sampling method. Force Vital Capacity was measured by using a spirometer. Heart rate variability measurement was done using a POLAR M400 heart rate monitor connected to the Welltory application by measuring the HRV parameter in the form of SDNN (standard deviation of normal to normal). Force Vital Capacity of respondents was in the range 1.82 – 3.47 Liters and had a mean of 2,722.72 ± 0.42 L. Mean HRV (SDNN) was 57.72 ± 23.77 ms. Bivariate analysis used Pearson's correlative parametric test. The results of the Pearson correlation test between FVC and SDNN showed a value of r = 0.282 and p = 0.124. There is no correlation between heart rate variability and vital lung capacity.

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