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Contact Name
Salman
Contact Email
salman.kimia@gmail.com
Phone
+6285277011177
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admin@journal-jps.com
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Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123
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Kota medan,
Sumatera utara
INDONESIA
Journal of Pharmaceutical and Sciences.
ISSN : -     EISSN : 26563088     DOI : https://doi.org/10.36490/journal-jps.com
Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports
Articles 62 Documents
Search results for , issue "JPS Volume 9 Nomor 1 (2026)" : 62 Documents clear
Efektivitas Antijamur Kombinasi Ekstrak Bajakah (Uncaria acida) dan Bandotan (Ageratum conyzoides) pada Mencit dengan Onikomikosis yang Terinfeksi Trichophyton rubrum Najhah, Nor Rezqiyatun; Rohmadi, Mukhlis; Indahsari, Lilin Ika Nur
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1392

Abstract

Onychomycosis is a fungal infection of the nail predominantly caused by Trichophyton rubrum and requires safer alternative therapies compared to synthetic antifungal agents. The combination of plant extracts may produce synergistic effects through interactions among bioactive compounds with complementary antifungal mechanisms. This study aimed to evaluate the effectiveness of a combined extract of Bajakah root (Uncaria acida) and Bandotan leaf (Ageratum conyzoides) as a topical therapy in T. rubrum–induced Balb/c mice. The selection of this combination was based on the presence of flavonoids, tannins, alkaloids, terpenoids, and saponins in both plants, which are theoretically associated with antifungal activity. Extracts were obtained by 96% ethanol maceration and formulated into ointments at concentrations of 25%, 50%, 75%, and 100%. Clinical parameters observed included periungual swelling, lesion diameter, nail discoloration, and nail brittleness. Phytochemical analysis confirmed the presence of major bioactive secondary metabolites in both extracts. The results demonstrated clinical improvement in all treatment groups, with the most pronounced effects observed at concentrations of 75–100%. Kruskal–Wallis analysis revealed significant differences among treatments (p < 0.05) for all parameters, which were further confirmed by Dunn’s post hoc test. Overall, the combined extracts of U. acida and A. conyzoides effectively reduced the severity of T. rubrum–induced onychomycosis and show potential as a natural antifungal candidate derived from local plant resources.
Permasalahan Terkait Obat pada Pasien Skizofrenia Rawat Inap: Tinjauan Sistematik Mengenai Prevalensi dan Intervensi Fatimah , Salma Auliya; Harjaningsih , Woro; Budiman , Bambang Hasta Yoga Legawa; Kurniawati , Fivy
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1458

Abstract

Schizophrenia is a severe mental disorder with increasing prevalence. Treatment for schizophrenia is chronic and often leads to Drug-Related Problems (DRPs), especially in hospitalized schizophrenia patients. This systematic review aims to map the prevalence and most common types of DRPs and evaluate the impact of clinical pharmacist involvement in addressing DRPs. A literature search was conducted across six electronic databases (Scopus, PubMed, ScienceDirect, Web of Science, ProQuest, and Springer Nature) for publications published between January 2009 and December 2024. Eleven studies met the inclusion criteria, consisting of nine cross-sectional studies and two quasi-experimental studies, with a total of over 61,000 hospitalized schizophrenia patients. The prevalence of DRPs has been reported to range from 52.8% to 100%, depending on the study design and the DRP identification method. Studies using structured medication reviews reported a higher DRP burden, at 0.75–2.5 DRPs per patient. The most frequently identified types of DRPs include polypharmacy, drug interactions, inappropriate medication selection, and dosing problems (overdose and underdose). QTc prolongation was reported in 2.5–8.26% of patients. Clinical pharmacist involvement was reported in three studies, with physician acceptance of recommendations ranging from 49 to 50%. DRPs are a common problem in hospitalized patients with schizophrenia, and clinical pharmacist involvement has the potential to improve the rationality and safety of drug therapy.