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In Silico Study: Potential Prediction of Curcuma longa And Cymbopogon citratus Essential Oil As Lipoxygenase Inhibitor Bare, Yohanes; Indahsari, Lilin Ika Nur; Sari, Dewi Ratih Tirto; Watuguly, Theopilus
JSMARTech: Journal of Smart Bioprospecting and Technology Vol 2, No 2 (2021)
Publisher : JSMARTech

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jsmartech.2021.002.02.75

Abstract

Abstract: Inflammation is the human body response by the injure as a results the inflammation will release LOX. To curve the conditions we use the bioactive from the nature are essential oil from Curcuma longa and Cymbopogon citratus because has a potential has pharmacologist activity. The purpose of this research to investigate the role essential oil from Curcuma longa and Cymbopogon citratus through LOX gene. Several chemical substances, including 3,7-dimethyl-1,3,6-octatriene, camphor, eugenol, curzerene and isoborneol were retrivied from PubChem database. The PyRx 0.8 was used to minimize and convert the sdf file to pdb format file of ligands. Those compounds were predicted their interaction using STITCH online server. Ligands and protein were docked by HEX Cuda 8.0.0 program, 3D and 2D views were evaluated using Discovery studio ver.19.0.0 and LigPlot+ ver 2.2, respectively. We found fourteen amino acid residues from LOX which bound the chemical compounds. Those interaction was supported by hydrogen bond with variety energy binding. To sum up, the essential oil from Curcuma longa and Cymbopogon citratus has a potential function as inhibitor LOX by inhibiting fourteen active side of the LOX gene. 
Pendampingan Budidaya Hidroponik Sederhana Kepada Siswa Magang di SKM Farm Kota Palangka Raya Indahsari, Lilin Ika Nur
Mujtama Jurnal Pengabdian Masyarakat Vol 3, No 2 (2023): Mujtama’ Jurnal Pengabdian Masyarakat
Publisher : Universitas Muhammadiyah Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32528/mujtama.v3i2.19989

Abstract

Hidroponik adalah teknik budidaya pertanian tanpa menggunakan media tanah, sehingga hidroponik merupakan aktivitas pertanian yang dijalankan dengan menggunakan air sebagai medium untuk menggantikan tanah. Pertanian dengan menggunakan sistem hidroponik memang tidak memerlukan lahan yang luas dalam pelaksanaannya, tetapi dalam bisnis pertanian hidroponik hanya layak dipertimbangkan mengingat dapat dilakukan di pekarangan rumah,atap rumah, lingkungan sekolah maupun lahan lainnya. Akan tetapi, seperti lingkungan sekolah masih banyak yang belum ada yang memiliki hidroponik untuk pengetahuan siswanya. masih minimnya wawasan dan keterampilan siswa-siswa untuk mengembangkan hidroponik disekolah. Oleh karena itu, perlu adanya program pendampingan budidaya Hidroponik sederhana kepada siswa dengan memanfatkan Stryrofoam bekas, agar dapat menambah wawasan, keterampilan dan kreativitas siswa disekolah. Metode pelaksanaan dari pengabdian masyarakat adalah memberikan pemahaman teori dan praktek. Hasil kegiatan pengabdian ini akan memberikan pemahaman teori dan pengalaman budidaya hidroponik sederhana kepada siswa-siswi Sekolah Menengah Kejuruan serta menambah semangat belajar siswa.
THE EFFECT OF THE COMBINATION OF BAY LEAVES (Syzygium polyanthum) AND BREADFRUIT LEAVES (Artocarpus altilis) ON CHOLESTEROL LEVELS IN HYPERCHOLESTEROLEMIC MICE Sapitri, Nabila; Lestariningsih, Nanik; Indahsari, Lilin Ika Nur
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol. 11 No. 2 (2025): Biolink February
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v11i2.13354

Abstract

Central Kalimantan has enormous natural resource potential, particularly in the area of medicinal plants such as bay leaves and breadfruit. Although, people in Central Kalimantan have utilized herbs as medicine, there has not been any scientific study done. This study aims to determine the effect of giving a combination of bay leaf and breadfruit leaf extracts in reducing cholesterol levels in Balb/c Hypercholesterolaemia mice. This study was conducted using the Mixed Method method, namely exploratory research and experimental research. The research subjects used were 28 female Balb/c mice in Hypercholesterolaemia conditions. In this study there were 7 treatments including positive control, negative control, P1 (20)%, P2 (30)%, P3 (40)%, P4 (50)%, P5 (60)% with 4 replications. The data analysis technique used in this study was One Way ANOVA. The finding of the study indicate that the combination of Bay Leaves and Breadfruit Leaves has an effect on reducing cholesterol levels in hypercholesterolemic mice, which can be seen from the p-value α (α 0.05) which is 0.000. Additionally, the most effective concentration in reducing cholesterol levels in hypercholesterolemic mice resulting in the concentration of P6 (50%) with a decrease of 60.25 Mg/dL.
Optimalisasi Branding dan Marketing Kerajinan Menjawet Rotan Khas Dayak di Desa Sepang Simin, Gunung Mas, Kalimantan Tengah Indahsari, Lilin Ika Nur; Muawwanah, Raudatul; Hafifah, Nur; Sholekhatun, Siti; Nurhaliza, Nurhaliza; Rizkyah; Akbar, Reinaldi; Amin , Zulva Sahrul
Welfare : Jurnal Pengabdian Masyarakat Vol. 2 No. 3 (2024): Welfare : September 2024
Publisher : Fakultas Ekonomi dan Bisnis Islam, IAIN Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30762/welfare.v2i3.1612

Abstract

Jawet is a traditional weaving technique that has been passed down from generation to generation in the Dayak community of Sepang Simin Village. This handicraft has obstacles, namely the lack of human resources to help and manage the woven jawet products and market them. This community service activity aims to optimize the branding and marketing of the local heritage of jawet weaving craftsmen in Sepang Simin Village, Gunung Mas Regency, Central Kalimantan Province. This community service activity uses the ABCD model for rattan jawet craftsmen. The results of the community service activity show that jawet weaving not only functions as a handicraft product, but also as a symbol of the cultural identity of the local community. Product branding is done by naming the product "Jawetan Dayak". Product marketing is optimized through social media Instagram and Facebook to reach a wider market. Marketing is done with a contemporary promotional design so that it can reach a wider market segment. The results of this product branding and marketing have proven to have increased the market reach of jawetan products because buyers can make transactions through social media.
Pelatihan Kewirausahaan di J2 FARM Hidroponik Palangkaraya sebagai Upaya Peningkatan Life Skill Mahasiswa Indahsari, Lilin Ika Nur; Alia, Rahmah; Siammukaromah, Jamalika Bunga Nur; Meiana, Nurma Alya; fatimah, fatimah
Mujtama Jurnal Pengabdian Masyarakat Vol 4, No 2 (2024): Mujtama’ Jurnal Pengabdian Masyarakat
Publisher : Universitas Muhammadiyah Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32528/mujtama.v4i2.22664

Abstract

Perkembangan zaman yang semakin kompetitif menuntut generasi muda untuk mempersiapkan diri guna menghadapi ketatnya persaingan dalam dunia kerja yang akan mereka hadapi. Pengembangan pengetahuan, soft skill maupun hard skill dibutuhkan tentunya sangat diperlukan untuk mempersiapkan diri dalam menghadapi hal tersebut. Mengikuti kegiatan yang diadakan oleh perguruan tinggi merupakan salah satu yang dapat membangun dan memberdayakan dalam keterampilan life skill mereka. Tujuan dari pelatihan yang dilakukan untuk meningkatkan life skill mahasiswa melalui pengembangan keterampilan budidaya hidroponik pada sayur yang bersifat consumable. Kegiatan pelatihan ini menggunakan metode praktik langsung yang diberikan oleh pimpinan pelaku usaha hidroponik. Kegiatan hidroponik yang dilakukan seperti penyemaian, pindah tanam ke instalansi dan tanap panen, dengan adanya pemberian pelatihan ini mahasiswa mampu mendapatkan ilmu budidaya hidroponik yang mana menambah life skill mahasiswa.