cover
Contact Name
Kuntaman
Contact Email
jcmidpamki@gmail.com
Phone
+6281337051550
Journal Mail Official
jcmidpamki@gmail.com
Editorial Address
Departemen Mikrobiologi, Fakultas Kedoteran Universitas Airlangga, Jl. Prof. Dr. Moestopo 47 Surabaya 60286
Location
Kota surabaya,
Jawa timur
INDONESIA
Journal of Clinical Microbiology and Infectious Diseases
ISSN : -     EISSN : 28089405     DOI : https://doi.org/10.51559/jcmid
Core Subject : Science,
Journal of Clinical Microbiology and Infectious Diseases; peer-reviewed journal aiming to communicate high-quality research articles, reviews, and general articles in the field. JCMID publishes articles that encompass basic research/clinical studies related to microbiology and infectious disease. The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of medical scholarship and encourage a vigorous dialogue between medical scholars and practitioners.
Articles 6 Documents
Search results for , issue "Vol. 4 No. 2 (2024): Available online : 1 December 2024" : 6 Documents clear
Case report of Stenotrophomonas maltophilia in corneal ulcer: why is it difficult to treat? Kusumadewi, Yolanda Pitra; Karina, Stefani Melisa; Setyowati, Reny; Suhardjo; Rizki, Ludhang Pradipta
Journal of Clinical Microbiology and Infectious Diseases Vol. 4 No. 2 (2024): Available online : 1 December 2024
Publisher : Indonesian Society for Clinical Microbiology (Perhimpunan Dokter Spesialis Mikrobiologi Klinik Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jcmid.v4i2.60

Abstract

Introduction: Stenotrophomonas maltophilia is an opportunistic bacterium and has rarely been reported as a cause of infection in the cornea. Ocular infection due to Stenotrophomonas maltophilia is an opportunistic infection followed by instability of the ocular surface. Casalita et al. (2020), in their research at Cipto Mangunkusumo Hospital, Jakarta, Indonesia found two cases of infected corneal ulcers due to Stenotrophomonas maltophilia. Case description: A 57-year-old man came to the eye clinic with pain in the left eye and blurred vision. The patient was diagnosed with severe corneal ulcer and regularly came for the treatment. The patient felt that his eye suddenly got worse with visual acuity only to his hand movement. Corneal ulcer swab procedure is performed when the patient firstly visit the clinic. Samples are sent to the microbiology laboratory for culture examination. Culture results obtained were coagulase negative Staphylococcus and Stenotrophomonas maltophilia. Conclusion: Stenotrophomonas maltophilia has several virulence factors, including resistance to various antibiotics, making it difficult to treat.
Post-Bronchoscopy Infections: A Literature Review: A Literature Review Permatasari, Tri Wijayanti; Karuniawati, Anis
Journal of Clinical Microbiology and Infectious Diseases Vol. 4 No. 2 (2024): Available online : 1 December 2024
Publisher : Indonesian Society for Clinical Microbiology (Perhimpunan Dokter Spesialis Mikrobiologi Klinik Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jcmid.v4i2.61

Abstract

Post-bronchoscopy infections are a critical concern in respiratory medicine, given their potential to exacerbate patient morbidity, particularly among immunocompromised individuals or those with pre-existing lung conditions, one of which is infection. The infection arises from lower respiratory tract pathogens, and most infections originate from reprocessing practices. Infection can occur when the bronchoscope comes into contact with the mucosa and blood vessels of the respiratory tract. Bacteremia is a more often post-bronchoscopy infection complication rather than pneumonia. It is commonly involving Coagulase-negative or positive Staphylococcus, non-hemolytic or hemolytic Streptococcus, Citrobacter species, and Klebsiella. However, in general, the incidence of post-bronchoscopy infection is mainly caused by gram-negative bacteria. Various risks can affect post-bronchoscopy infection that can increase the severity of the disease to death. It is important to increase obedience and precaution against the transmission of infection. Reducing bacterial pathogens and controlling infection are important steps to reduce the post-bronchoscopy infection mortality rate. Therefore, this study aimed to review the post-bronchoscopy infections in detail.
Rare case of human Streptococcus suis purpura fulminans at Prof. Ngoerah Hospital, Denpasar, Bali Nara Dhany, Henri; Tarini, Ni Made Adi; Putrawan, Ida Bagus Putu; Pinatih, Komang Januartha Putra
Journal of Clinical Microbiology and Infectious Diseases Vol. 4 No. 2 (2024): Available online : 1 December 2024
Publisher : Indonesian Society for Clinical Microbiology (Perhimpunan Dokter Spesialis Mikrobiologi Klinik Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jcmid.v4i2.63

Abstract

Background: Streptococcus suis (S. suis) is a zoonotic bacterium capable of causing severe infections in humans, particularly those with occupational exposure to pigs or pork products. Notable manifestations include meningitis, endocarditis, sepsis, and distinct skin conditions such as purpura and necrotic lesions. Southeast Asia reports the highest incidence, correlating with prevalent pig farming practices. Though infrequent, S. suis infections can lead to severe outcomes if not promptly diagnosed and treated. Case Presentation: We present a case involving a 73-year-old Balinese man without recent exposure to pigs or pork but with a history of pork consumption six months prior. He was admitted with symptoms including skin discoloration, respiratory distress, and loss of consciousness. Physical and laboratory examinations revealed pleural effusion, pneumonia, and high procalcitonin levels. Blood cultures identified S. suis, confirmed by VITEK® 2 system with susceptibility to multiple antibiotics, except tetracycline. Despite initial treatment with ceftriaxone, azithromycin, and levofloxacin; the patient’s condition deteriorated, resulting in a fatal outcome. Conclusion: This case underscores the importance of early diagnosis and rapid antibiotic intervention in S. suis infection. Delay in hospitalization significantly impacts prognosis, and timely, targeted treatment could improve survival rates. Enhanced awareness and preventive strategies in high-risk areas are vital to reducing the incidence and mortality associated with this infection.
Non-dermatophytic onychomycosis caused by Fusarium spp. in a 58-year-old agricultural worker: a case report Aminy, Sayyidah A.; Amaia, Devika N.; Soebono, Hardyanto; Nuryastuti, Titik
Journal of Clinical Microbiology and Infectious Diseases Vol. 4 No. 2 (2024): Available online : 1 December 2024
Publisher : Indonesian Society for Clinical Microbiology (Perhimpunan Dokter Spesialis Mikrobiologi Klinik Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jcmid.v4i2.66

Abstract

Introduction: Onychomycosis is a nail infection caused by dermatophytes, non-dermatophytes, and yeast. Fusarium spp. is one of the non-dermatophyte molds that can cause onychomycosis. A superficial infection with these fungi can lead to an invasive infection. Few case reports of onychomycosis caused by Fusarium spp. in Indonesia have been documented. Case description: We present a case of a 58-year-old male patient with a history of hepatitis B, atopic dermatitis, and corticosteroid consumption. Hyperkeratosis with a yellowish color was observed, and small particles of cornified material were discovered beneath both of his great toenails. Onychomycosis is assessed based on clinical symptoms. Mycological examinations were done by KOH examination and culture. Macroscopic examination of the culture revealed a white, cottony-looking mold with a non-pigmented reverse. Microscopic examination showed the septate hyphae, the canoe-shaped macroconidia, and the oval microconidia. We diagnosed onychomycosis caused by Fusarium spp. Based on macroscopic and microscopic examination. The antifungal susceptibility test showed a high MIC against several antifungal agents. Conclusion: It is important to be cautious for onychomycosis caused by Fusarium spp. infection as superficial infection can progress to invasive disease. Given the high prevalence of Fusarium spp. resistance to the antifungal group, antifungal treatment selection should be carefully considered.
Neisseria gonorrhoeae and Chlamydia trachomatis coinfection in a 20-year-old man with recurrent urethritis: a case report Prawarni, Vidyadhari Puspa; Prameshwara, Almarissa Ajeng; Susetiati, Devi Artami; Nuryastuti, Titik
Journal of Clinical Microbiology and Infectious Diseases Vol. 4 No. 2 (2024): Available online : 1 December 2024
Publisher : Indonesian Society for Clinical Microbiology (Perhimpunan Dokter Spesialis Mikrobiologi Klinik Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jcmid.v4i2.67

Abstract

Introduction: Neisseria gonorrhoeae and Chlamydia trachomatis are the two pathogens most commonly reported to cause sexually transmitted infections (STIs) worldwide. Coinfection between these two pathogens has been widely reported, but the incidence is still rarely reported due to challenges in diagnosis to prove the involvement of the two pathogens simultaneously. The molecular diagnostic approach is an effective option for this case and optimizing this method will able to help clinicians deciding management for the patients and prevent the spreading of the disease. This study aimed to present a case of N. gonorrhoeae and C. trachomatis coinfection in a 20-year-old man with recurrent urethritis. Case Description: A 20-year-old man presented to the Dermatology and Venereology clinic at Dr. RSUP. Sardjito with purulent discharge from the penis started a week prior. From the anamnesis and physical examination, the doctors suspected this patient with N. gonorrhoeae infection. N. gonorrhoeae was detected by microscopic examination, culture, and Real-Time Polymerase Chain Reaction (RT-PCR) examination, while C. trachomatis was also detected in RT-PCR. The patient was treated with azithromycin 1-gram single dose and cefixime 400 mg single dose. Discussion: The World Health Organization (WHO) reported that the incidence of STIs is always increasing. Most STIs are usually asymptomatic, but it can be presented as urethritis in male patients. For females, it can be given as leucorrhoea, pelvic inflammatory disease (PID), or other pregnancy complications. N. gonorrhoeae and C. trachomatis are the two main pathogens always reported annually and often found as coinfection. Due to the virulence factors of these bacteria, N. gonorrhoeae and C. trachomatis are very hard to diagnose with conventional culture methods, and the molecular approach is now an effective option to detect them and help prevent recurrence. Conclusion: Coinfection of N. gonorrhoeae and C. trachomatis is a case that is quite often encountered in clinical practice, but the incidence is rarely reported due to supporting examination methods to help confirm the presence of these two microorganisms are still limited. In cases of suspected infection by N. gonorrhoeae, C. trachomatis, or both simultaneously, the most recommended microbiological examination is to use molecular diagnostics such as PCR.
Ceftriaxone-and-cefixime-resistant Neisseria gonorrhoeae in a 26-year-old-male with gonococcal urethritis: a case report Prameshwara, Almarissa Ajeng; Prawarni, Vidyadhari Puspa; Susetiati, Devi Artami; Nuryastuti, Titik
Journal of Clinical Microbiology and Infectious Diseases Vol. 4 No. 2 (2024): Available online : 1 December 2024
Publisher : Indonesian Society for Clinical Microbiology (Perhimpunan Dokter Spesialis Mikrobiologi Klinik Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jcmid.v4i2.68

Abstract

Introduction: Gonorrhoea is the most prevalent sexually transmitted infection (STI) in Indonesia. The increasing resistance of Neisseria gonorrhoeae to antibiotics has prompted the World Health Organization (WHO) to classify gonorrhoea as an urgent public health threat. Reports of resistance to third generation extended-spectrum cephalosporins (ESCs), such as cefixime and ceftriaxone, against N. gonorrhoeae are rare in Indonesia. This study aims to present a case of cefixime and ceftriaxone resistance in a 26-year-old man with gonococcal urethritis. Case Description: A 26-year-old man presented to an STI clinic with a two-week history of increased urethral discharge. He reported a history of sexual activity with multiple partners. Physical examination revealed mucopurulent exudate and thick greenish-white pus from the external genitalia. Microscopic examination of a urethral smear identified numerous polymorphonuclear cells (>10 PMN/high-power field) and Gram-negative intracellular diplococci. Bacterial culture confirmed the presence of Gram-negative diplococci consistent with N. gonorrhoeae. Polymerase chain reaction (PCR) testing further confirmed N. gonorrhoeae. Susceptibility testing revealed resistance to both cefixime and ceftriaxone. The patient was treated with dual therapy, consisting of a single oral dose of azithromycin (1 g) and cefixime (400 mg). Complete symptom resolution was achieved within one week. Conclusion: Third-generation ESCs, including injectable ceftriaxone and orally administered cefixime, are the most commonly used antibiotics for gonorrhoea treatment. Resistance to these drugs represents a significant global health threat. Discrepancies between antibiotic susceptibility test results and clinical outcomes highlight the need for further investigation into underlying factors contributing to treatment efficacy.

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